Mybpc2 (myosin binding protein C, fast-type)

Gene: Mybpc2 (myosin binding protein C, fast-type) Mus musculus

Analyze

Symbol:

Mybpc2

Name:

myosin binding protein C, fast-type

RGD ID:

1323137

MGI Page

MGI

Description:

Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in sarcomere organization. Predicted to act upstream of or within cytoskeleton organization and muscle contraction. Predicted to be located in cytoskeleton. Predicted to be active in M band. Is expressed in diaphragm; extensor digitorum longus; hindlimb; rectus femoris; and soleus. Orthologous to human MYBPC2 (myosin binding protein C2).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

C-protein, skeletal muscle fast isoform; fast MyBP-C; fast-type C-protein; MGC28149; myosin-binding protein C, fast-type

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MYBPC2 (myosin binding protein C2)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Mybpc2 (myosin binding protein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mybpc2 (myosin binding protein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MYBPC2 (myosin binding protein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MYBPC2 (myosin binding protein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mybpc2 (myosin binding protein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MYBPC2 (myosin binding protein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MYBPC2 (myosin binding protein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mybpc2 (myosin binding protein C2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MYBPC3 (myosin binding protein C3)	HGNC	OrthoMCL
Homo sapiens (human):	MYBPC1 (myosin binding protein C1)	HGNC	OrthoMCL
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Mybpc2 (myosin binding protein C2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MYBPC2 (myosin binding protein C2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mybpc2a (myosin binding protein C, fast type a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Danio rerio (zebrafish):	mybpc2b (myosin binding protein C, fast type b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	CG14964	Alliance	DIOPT (Ensembl Compara\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,151,123 - 44,174,093 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,151,123 - 44,174,080 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	44,501,699 - 44,524,715 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	44,501,699 - 44,524,656 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	51,757,069 - 51,780,039 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	44,369,741 - 44,392,696 (-)	NCBI		MGSCv36	mm8
Celera	7	39,951,620 - 39,974,810 (-)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	28.83	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Contracture (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (EXP)

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

6-propyl-2-thiouracil (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (EXP)

alpha-Zearalanol (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (EXP,ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

carbon nanotube (EXP)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

dextran sulfate (EXP)

dichloroacetic acid (EXP)

disodium selenite (EXP)

dorsomorphin (ISO)

doxorubicin (EXP,ISO)

entinostat (ISO)

ethyl methanesulfonate (ISO)

genistein (EXP)

GW 4064 (EXP)

imidacloprid (ISO)

lidocaine (ISO)

methyl methanesulfonate (ISO)

mono(2-ethylhexyl) phthalate (EXP)

ozone (EXP)

paracetamol (ISO)

paraquat (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (ISO)

progesterone (EXP)

SB 431542 (ISO)

stigmasterol (EXP)

tamoxifen (EXP)

titanium dioxide (EXP)

trichloroethene (ISO)

triptonide (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IEA)

cytoskeleton organization (TAS)

muscle contraction (TAS)

sarcomere organization (IBA)

Cellular Component

cytoskeleton (TAS)

M band (IBA)

myosin filament (IEA)

Molecular Function

actin binding (IEA)

protein binding (ISO)

structural constituent of cytoskeleton (TAS)

References

References - curated

#	Reference Title	Reference Citation
1.	MGDs mouse GO annotations	MGD data from the GO Consortium
2.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8618961	PMID:9440711	PMID:9493956	PMID:10024132	PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12477932	PMID:15489334	PMID:16141072	PMID:16141073
PMID:19506036	PMID:21267068	PMID:21565611	PMID:21873635	PMID:23236519	PMID:26075897	PMID:29543863	PMID:30410445	PMID:32325033	PMID:32434143	PMID:33888578	PMID:36409445
PMID:37468485

Genomics

Comparative Map Data

Mybpc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,151,123 - 44,174,093 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,151,123 - 44,174,080 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	44,501,699 - 44,524,715 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	44,501,699 - 44,524,656 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	51,757,069 - 51,780,039 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	44,369,741 - 44,392,696 (-)	NCBI		MGSCv36	mm8
Celera	7	39,951,620 - 39,974,810 (-)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	28.83	NCBI

MYBPC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	50,432,892 - 50,466,321 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	50,432,892 - 50,466,321 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	50,936,149 - 50,969,578 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	55,627,972 - 55,661,395 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	55,628,003 - 55,661,389	NCBI
Celera	19	47,986,406 - 48,019,748 (+)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	47,274,410 - 47,307,386 (+)	NCBI		HuRef
CHM1_1	19	50,937,951 - 50,971,330 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	53,520,453 - 53,553,838 (+)	NCBI		T2T-CHM13v2.0

Mybpc2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,130,642 - 104,154,101 (-)	NCBI		GRCr8
mRatBN7.2	1	94,994,121 - 95,017,584 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	94,994,104 - 95,017,584 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	100,379,523 - 100,402,988 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	108,852,171 - 108,875,632 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,142,596 - 102,166,053 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	100,506,704 - 100,530,201 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,506,704 - 100,530,183 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	101,572,091 - 101,595,585 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	94,979,308 - 95,002,804 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	95,057,418 - 95,080,913 (-)	NCBI
Celera	1	89,256,672 - 89,280,050 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Mybpc2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	681,112 - 703,026 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	681,004 - 703,163 (-)	NCBI	ChiLan1.0	ChiLan1.0

MYBPC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	56,497,928 - 56,533,047 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	58,419,366 - 58,453,802 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	47,395,971 - 47,430,399 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	56,301,775 - 56,331,384 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	56,299,518 - 56,331,268 (+)	Ensembl	panpan1.1		panPan2

MYBPC2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	106,266,817 - 106,292,740 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	106,266,817 - 106,301,686 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	105,839,919 - 105,865,862 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	106,777,885 - 106,803,838 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	106,777,890 - 106,803,762 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	106,450,080 - 106,475,987 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	106,091,553 - 106,117,489 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	106,932,214 - 106,958,160 (-)	NCBI		UU_Cfam_GSD_1.0

Mybpc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	22,383,065 - 22,407,039 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936889	265,047 - 283,020 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936889	259,055 - 283,023 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MYBPC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	55,281,803 - 55,310,295 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	55,281,991 - 55,310,184 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	51,131,387 - 51,159,090 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MYBPC2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	43,493,862 - 43,530,931 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	43,494,619 - 43,531,554 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	23,480,872 - 23,519,107 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mybpc2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	4,084,678 - 4,109,515 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	4,089,361 - 4,109,182 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mybpc2
568 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	87
Count of miRNA genes:	76
Interacting mature miRNAs:	86
Transcripts:	ENSMUST00000165208
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300722	Sle3_m	systemic lupus erythmatosus susceptibility 3 (mouse)			Not determined		7	3511728	87142720	Mouse
38501068	Tip1_m	tuberculosis immunophenotype 1, spleen CFU (mouse)					7	3602999	72549748	Mouse
25314307	Mlh1fc2_m	MLH1 foci count 2 (mouse)					7	6502999	133501729	Mouse
12792978	Fbmd3_m	femoral bone mineral density 3, females only (mouse)					7	7050288	142367832	Mouse
1558893	Spir1_m	Streptococcus pneumoniae infection resistance 1 (mouse)			Not determined		7	10305798	44305936	Mouse
10449139	Eosn1_m	eosinophil differential 1 (mouse)					7	12480877	46480877	Mouse
10449158	Eosn3_m	eosinophil differential 3 (mouse)					7	12480877	46480877	Mouse
4141566	Femwf8_m	femur work to failure 8 (mouse)			Not determined			13032485	47032621	Mouse
11522751	Cocia17_m	cocaine-induced activity, QTL 17 (mouse)					7	13135204	47135204	Mouse
25314314	Sccor1_m	synaptonemal complex length to mean MLH1 count ratio 1 (mouse)					7	13333925	47349748	Mouse
1559016	Drsi_m	DCC-related Spp1 induction (mouse)			Not determined		7	16637293	49159331	Mouse
10412199	Sst2_m	susceptibility to tuberculosis 2 (mouse)			Not determined		7	18728794	119485380	Mouse
1301158	Eae4_m	susceptibility to experimental allergic encephalomyelitis 4 (mouse)			Not determined		7	19147398	141919804	Mouse
1301622	Eae12_m	susceptibility to experimental allergic encephalomyelitis 12 (mouse)			Not determined		7	19280015	53280104	Mouse
1301052	Bhr6_m	bronchial hyperresponsiveness 6 (mouse)			Not determined		7	19842250	53842367	Mouse
12904742	Litsq2_m	litter size QTL 2 (mouse)					7	22673887	56674033	Mouse
1301709	Bdt4_m	bone density traits 4 (mouse)			Not determined		7	22888572	56888716	Mouse
11354952	Pdcc1_m	plasmacytoid dentritic cell compartment 1 (mouse)					7	23066531	57066531	Mouse
1301969	Lbw5_m	lupus NZB x NZW 5 (mouse)			Not determined		7	26847615	60851775	Mouse
12790989	Tgl6_m	triglyceride 6 (mouse)					7	27540549	61540549	Mouse
4141805	Sle19_m	systematic lupus erythematosus susceptibility 19 (mouse)			Not determined			30032485	81135653	Mouse
26884404	Huml1_m	humerus length 1, 5 week (mouse)					7	30199425	108999207	Mouse
1301175	Ap7q_m	alcohol preference 7 QTL (mouse)			Not determined		7	31714845	65715077	Mouse
1300996	Aorls2_m	aortic lesion size 2 (mouse)			Not determined		7	32394532	66394681	Mouse
4142003	W3q10_m	weight 3 weeks QTL 10 (mouse)			Not determined			33497727	58148965	Mouse
4142102	Tailq5_m	tail length QTL 5 (mouse)			Not determined			33497727	58148965	Mouse
4142218	W6q17_m	weight 6 weeks QTL 17 (mouse)			Not determined			33497727	58148965	Mouse
4141909	W10q18_m	weight 10 weeks QTL 18 (mouse)			Not determined			33497727	58148965	Mouse
1357883	Epfq5_m	epididymal fat pad weight QTL 5 (mouse)			Not determined		7	33497727	58148965	Mouse
1357634	Splq7_m	spleen weight QTL 7 (mouse)			Not determined		7	33497727	58148965	Mouse
39128210	Lwq19_m	liver weight QTL 19 (mouse)					7	33497727	58148965	Mouse
1357469	Kidq5_m	kidney weight QTL 5 (mouse)			Not determined		7	33497727	58148965	Mouse
1559000	Ossc1_m	osteosarcoma susceptibility 1 (mouse)			Not determined		7	34053025	68053223	Mouse
38501071	Stsl6_m	Salmonella typhimurium susceptibility locus 6 (mouse)					7	34199425	51149748	Mouse
10045622	Heal20_m	wound healing/regeneration 20 (mouse)			Not determined		7	34316887	68317043	Mouse
1357586	Mdmsc3_m	modifier of muscularity 3 (mouse)			Not determined		7	34447869	68448018	Mouse
1301514	Rigs1_m	radiation induced gastroschisis 1 (mouse)			Not determined		7	36280015	92394346	Mouse
1301082	Bbaa16_m	B.burgdorferi-associated arthritis 16 (mouse)			Not determined		7	36280015	116416877	Mouse
25314301	Vmm3_m	variable multisystem mineralization 3, lung (mouse)					7	37299425	72049748	Mouse
25314303	Vmm4_m	variable multisystem mineralization 4, kidney (mouse)					7	37299425	87049208	Mouse
1300878	Skts1_m	skin tumor susceptibility 1 (mouse)			Not determined		7	37891386	71891582	Mouse
10402488	Dipa2_m	drug induced psychomotor activation 2 (mouse)			Not determined		7	38421548	72421684	Mouse
1300791	Abbp3_m	A/J and C57BL/6 blood pressure 3 (mouse)			Not determined		7	39673887	103510010	Mouse
11252140	Fdr1_m	fat response to dietary restriction 1 (mouse)					7	41148820	75148965	Mouse
4141929	Chlq18_m	circulating hormone level QTL 18 (mouse)			Not determined		7	41148820	75148965	Mouse

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_146189	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC149607	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK029282	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK132563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK161146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC029762	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC038869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC039184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466603	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK787764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000165208 ⟹ ENSMUSP00000130127

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	44,151,123 - 44,174,080 (-)	Ensembl
GRCm38.p6 Ensembl	7	44,501,699 - 44,524,656 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000207516 ⟹ ENSMUSP00000146698

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	44,155,632 - 44,158,502 (-)	Ensembl
GRCm38.p6 Ensembl	7	44,506,208 - 44,509,078 (-)	Ensembl

RefSeq Acc Id:

NM_146189 ⟹ NP_666301

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	44,151,123 - 44,174,093 (-)	NCBI
GRCm38	7	44,501,699 - 44,524,669 (-)	NCBI
MGSCv37	7	51,757,069 - 51,780,039 (-)	RGD
Celera	7	39,951,620 - 39,974,810 (-)	RGD
cM Map	7		ENTREZGENE

Sequence:

show sequence

TGGAGACCCACCTGTCCCTGCTAGGGCCTGGTTAGAGCCACTGCGGTCCCAAGTCCTGGGAGCA
GGAGAAGGTCGCCGACATGCCTGAGGCTAAACCAGCGGCCAAAAAGGCCTCCAAAGGCAAAGAT
GCCCCAAAGGAAGCCCCTGCAAAGCAGACTCCTGAAGAGCCCCCCAAAGAGGCCCCACCTGAGG
ACCAATCCCCAACTGCGGAGGAGCCCACAGGCATCTTCCTGAAAAAGCCGGACTCTGTGTCAGT
GGAGACTGGGAAAGACGCGGTGATTCTGGCCAAGGTGAACGGGAAGGAGCTCCCAGGCAAGCCG
ACCATCAAGTGGTTCAAGGGGAAGTGGCAGGAGCTGGGCAGCAAGAGCGGAGCCCGGTTCATCT
TCAAGGAATCTCATGACTCTACCAGCAATGTGTACACCGTGGAGCTCCACATTGGGAAGGTGGT
CCTAGGGGACCGCGGGGATTACCGTCTAGAGATCAAAGCCAAGGATGTCTGCGACAGCTGCTCG
TTCAACGTGGATGTGGAGGCACCCCGTCAGGACTCATCCGGTCAGAGCCTCGAGAGCTTCAAGC
GTTCGGGTGACGGGAAGTCAGAAGATGCAGGCGAGCTGGATTTCAGTGGCTTGTTGAAGAAGAG
GGAAGTAGTTGAGGAGGAGAAGAAGAAGAAGAAAGATGATGATGATCTGGGTATACCTCCGGAG
ATTTGGGAGCTCCTGAAAGGGGCCAAGAAGAGCGAGTACGAGAAGATCGCCTTCCAGTACGGCA
TCACTGACCTCCGTGGCATGCTGAAGCGGCTCAAGAAGGCCAAGGTGGAGGTCAAGAAGAGTGC
AGCCTTCACTAAGAAGTTGGACCCAGCCTACCAAGTAGACAGGGGCAACAAGATCAAGCTGGTG
GTGGAGATCAGTGACCCAGACCTTCCTCTCAAGTGGTTCAAGAATGGCCAGGAGATCAAACCAA
GCAGCAAGTATGTGTTTGAGAACGTTGGGAAGAAACGAATTCTTACCATCAACAAGTGCACGCT
GGCGGATGATGCTGCATACGAGGTGGCAGTCCAAGATGAGAAGTGTTTCACTGAACTCTTTGTC
AAAGAGCCCCCAGTCTTGATTGTCACCCCACTGGAGGACCAGCAGGTATTCGTAGGTGACCGAG
TGGAAATGTCGGTAGAGGTGTCAGAAGAGGGTGCACAGGTTATGTGGATGAAAGATGGTGTGGA
GATGACTCGGGAGGATTCCTACAAGGCGCGCTACCGCTTCAAGAAGGACGGGAAACGGCACATC
CTCATCTACTCTGATGTGGCCCAGGAGGATGGGGGCCGCTACCAGGTCATAACCAATGGTGGCC
AGTGTGAGGCTGAACTCATTGTGGAAGAGAAGCAACTGGAGGTCCTGCAGGACATTGCTGACCT
GACAGTGAAGGCTGCAGAGCAGGCTGTGTTCAAGTGTGAAGTGTCTGATGAGAAGGTGACAGGC
AAATGGTACAAGAACGGCGTGGAGGTACGACCCAGCAAGAGGATCACCATCTCCCATGTGGGCA
GATTCCACAAGCTGGTGATTGATGACGTCCGCCCTGAGGATGAGGGAGACTACACATTCGTGCC
CGATGGCTATGCCCTATCCCTCTCAGCCAAGCTCAACTTTTTGGAAATCAAAGTGGAGTATGTA
CCTAAGCAAGAGCCCCCGAAGATCCACCTGGACTGCTCAGGGAAGACCTCAGATAACTCAATTG
TTGTGGTGGCTGGAAACAAGCTGCGGCTGGATGTGGCCATCACAGGGGAACCACCTCCCACTGC
TACCTGGCTAAGGGGAGATGAGGTGTTCACAGCCACAGAAGGCAGGACACACATCGAGCAGAGG
CCAGACTGCAGCAGCTTTGTGATCGAGAGTGCGGAGCGGTCGGATGAGGGCCGCTACACCATCA
AAGTCACCAATCCTGTGGGCGAGGACGTGGCCTCCATTTTCCTGCGGGTTGTGGATGTTCCTGA
TCCTCCAGAGGCTGTCCGTGTCACCTCAGTTGGAGAAGACTGGGCCATTCTGGTCTGGGAGCCA
CCCAAGTATGATGGAGGACAGCCAGTGACTGGGTACTTGATGGAGCGGAAGAAGAAAGGCTCCC
AGCGCTGGATGAAGATCAACTTTGAGGTCTTCACTGACACCACCTACGAGTCCACAAAGATGAT
CGAGGGCGTCCTTTATGAGATGCGGGTCTTCGCTGTCAACGCCATTGGGGTCTCACAGCCCAGC
ATGAACACCAAGCCCTTCATGCCCATTGCTCCCACGAGTGCACCACAACACCTCACCGTGGAGG
ATGTGACGGACACCACCACCACACTTAAGTGGAGACCTCCAGATCGGATTGGTGCTGGTGGCAT
TGATGGCTACCTGGTGGAGTACTGCCTGGAGGGCTCTGAGGAATGGGTACCAGCTAACAAGGAG
CCAGTGGAACGCTGTGGCTTCACTGTCAAGGATCTCCCAACTGGAGCCAGGATCCTCTTCCGGG
TTGTTGGGGTCAACATCGCAGGGCGCAGTGAACCAGCCACCCTCCTTCAGCCAGTCACTATCAG
GGAGATTGTGGAGCAACCTAAGATCCGCCTTCCCCGCCATCTTCGTCAGACTTATATCCGAAAA
GTTGGGGAGGCCCTCAACCTCGTCATCCCCTTCCAGGGCAAGCCCCGGCCTCAGGTGGTGTGGA
CCAAGGGTGGGGCTCCCTTGGATACCTCCCGTGTGAATGTGCGGACTAGTGACTTCGACACAGT
GTTCTTCGTGCGACAGGCGGCCCGCTCTGACTCCGGAGAGTATGAGCTGAGTGTGCAGATTGAA
AACATGAAGGACACTGCTACCATACGCATCCGGGTCGTGGAAAAGGCAGGGCCAGCAGAGAATG
TGATGGTGAAGGAGGTGTGGGGCACAAATGCTCTGGTGGAGTGGCAGCCGCCCAAGGATGACGG
GAACAGTGAGATCACAGGCTACTTTGTCCAGAAGGCTGACAAAAAGACCATGGAGTGGTTCAAT
GTCTACGAACACAATCGCCACACCAGCTGTACGGTGTCTGACCTCATTGTGGGTAATGAGTACT
ACTTCCGTATCTTCAGCGAGAACATCTGCGGTCTCAGTGACTCGCCAGGTGTCTCCAAGAACAC
AGCTCGAATTCTCAAGACAGGAATCACCTTAAAACCACTGGAGTACAAGGAGCATGATTTCCGG
ACGGCTCCCAAGTTCCTGACCCCGCTGATGGACCGGGTCGTGGTGGCGGGATATACCGCAGCTC
TCAACTGTGCCGTCAGAGGCCACCCTAAGCCAAAGGTGGTGTGGATGAAGAACAAGATGGAAAT
CCATGAAGATCCCAAATTCCTCATAACCAACTACCAGGGCATCCTGACACTGAACATCCGCCGA
CCGTCACCCTTTGATGCAGGGACCTATTCCTGCCGCGCCTTCAATGAGCTGGGGGAAGCCCTGG
CTGAATGCAAACTGGATGTCCGAGTGCCACAGTGACAGCTCATCACCTGCTAAATAAGTCATCA
GAACCCGGACACCAGCGCTGCAACTCTTGGGATGGCAGTCATCTTTCCAGAATGATCACTGTGA
TAAAGAACTGTTGCTCAAATTATCATGTGTCCATCTTTCC

hide sequence

Protein Sequences


Protein RefSeqs	NP_666301	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH29762	(Get FASTA)	NCBI Sequence Viewer
	AAH39184	(Get FASTA)	NCBI Sequence Viewer
	BAC26371	(Get FASTA)	NCBI Sequence Viewer
	EDL22726	(Get FASTA)	NCBI Sequence Viewer
	EDL22727	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000130127
	ENSMUSP00000130127.3
	ENSMUSP00000146698.2
GenBank Protein	Q5XKE0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_666301 ⟸ NM_146189

- UniProtKB:

Q8C109 (UniProtKB/Swiss-Prot), Q8K2V0 (UniProtKB/Swiss-Prot), Q5XKE0 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MPEAKPAAKKASKGKDAPKEAPAKQTPEEPPKEAPPEDQSPTAEEPTGIFLKKPDSVSVETGKD
AVILAKVNGKELPGKPTIKWFKGKWQELGSKSGARFIFKESHDSTSNVYTVELHIGKVVLGDRG
DYRLEIKAKDVCDSCSFNVDVEAPRQDSSGQSLESFKRSGDGKSEDAGELDFSGLLKKREVVEE
EKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKK
LDPAYQVDRGNKIKLVVEISDPDLPLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAA
YEVAVQDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMSVEVSEEGAQVMWMKDGVEMTRED
SYKARYRFKKDGKRHILIYSDVAQEDGGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKAA
EQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYAL
SLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSDNSIVVVAGNKLRLDVAITGEPPPTATWLRG
DEVFTATEGRTHIEQRPDCSSFVIESAERSDEGRYTIKVTNPVGEDVASIFLRVVDVPDPPEAV
RVTSVGEDWAILVWEPPKYDGGQPVTGYLMERKKKGSQRWMKINFEVFTDTTYESTKMIEGVLY
EMRVFAVNAIGVSQPSMNTKPFMPIAPTSAPQHLTVEDVTDTTTTLKWRPPDRIGAGGIDGYLV
EYCLEGSEEWVPANKEPVERCGFTVKDLPTGARILFRVVGVNIAGRSEPATLLQPVTIREIVEQ
PKIRLPRHLRQTYIRKVGEALNLVIPFQGKPRPQVVWTKGGAPLDTSRVNVRTSDFDTVFFVRQ
AARSDSGEYELSVQIENMKDTATIRIRVVEKAGPAENVMVKEVWGTNALVEWQPPKDDGNSEIT
GYFVQKADKKTMEWFNVYEHNRHTSCTVSDLIVGNEYYFRIFSENICGLSDSPGVSKNTARILK
TGITLKPLEYKEHDFRTAPKFLTPLMDRVVVAGYTAALNCAVRGHPKPKVVWMKNKMEIHEDPK
FLITNYQGILTLNIRRPSPFDAGTYSCRAFNELGEALAECKLDVRVPQ

hide sequence

RefSeq Acc Id:

ENSMUSP00000130127 ⟸ ENSMUST00000165208

RefSeq Acc Id:

ENSMUSP00000146698 ⟸ ENSMUST00000207516

Protein Domains

Fibronectin type-III Ig-like C2-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XKE0-F1-model_v2	AlphaFold	Q5XKE0	1-1136	view protein structure

Promoters

RGD ID:

8663871

Promoter ID:

EPDNEW_M9967

Type:

multiple initiation site

Name:

Mybpc2_1

Description:

Mus musculus myosin binding protein C, fast-type , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	7	44,524,656 - 44,524,716	EPDNEW

RGD ID:

6841595

Promoter ID:

MM_KWN:50265

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Spleen

Transcripts:

ENSMUST00000064089, NM_146189

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	7	51,780,641 - 51,781,141 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1336170	AgrOrtholog
Ensembl Genes	ENSMUSG00000038670	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000165208	ENTREZGENE
	ENSMUST00000165208.4	UniProtKB/Swiss-Prot
	ENSMUST00000207516.2	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	FN3_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FN3_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom	UniProtKB/Swiss-Prot
	Ig-like_dom_sf	UniProtKB/Swiss-Prot
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/Swiss-Prot
	Ig_sub	UniProtKB/Swiss-Prot
	Ig_sub2	UniProtKB/Swiss-Prot
	MyBP-C_THB	UniProtKB/Swiss-Prot
KEGG Report	mmu:233199	UniProtKB/Swiss-Prot
MGD	MGI:1336170	ENTREZGENE
NCBI Gene	233199	ENTREZGENE
PANTHER	MYOSIN-BINDING PROTEIN C, FAST-TYPE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TITIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	fn3	UniProtKB/Swiss-Prot
	I-set	UniProtKB/Swiss-Prot
	THB	UniProtKB/Swiss-Prot
PhenoGen	Mybpc2	PhenoGen
PRINTS	FNTYPEIII	UniProtKB/Swiss-Prot
PROSITE	FN3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IG_LIKE	UniProtKB/Swiss-Prot
SMART	FN3	UniProtKB/Swiss-Prot
	IGc2	UniProtKB/Swiss-Prot
	SM00409	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot
	SSF49265	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A140LI70_MOUSE	UniProtKB/TrEMBL
	MYPC2_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q8C109	ENTREZGENE
	Q8K2V0	ENTREZGENE
UniProt Secondary	Q8C109	UniProtKB/Swiss-Prot
	Q8K2V0	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar