Smg7 (SMG7 nonsense mediated mRNA decay factor) - Rat Genome Database

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Gene: Smg7 (SMG7 nonsense mediated mRNA decay factor) Mus musculus
Analyze
Symbol: Smg7
Name: SMG7 nonsense mediated mRNA decay factor
RGD ID: 1321853
MGI Page MGI
Description: Predicted to enable protein phosphatase 2A binding activity; telomerase RNA binding activity; and telomeric DNA binding activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be located in cytosol and nucleus. Predicted to be part of telomerase holoenzyme complex. Orthologous to human SMG7 (SMG7 nonsense mediated mRNA decay factor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9430023P16Rik; EST1-like protein C; MGC91209; mKIAA0250; nonsense-mediated mRNA decay factor SMG7; Smg-7 homolog, nonsense mediated mRNA decay factor; Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391152,712,746 - 152,783,212 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1152,712,746 - 152,778,397 (-)EnsemblGRCm39 Ensembl
GRCm381152,836,995 - 152,903,130 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1152,836,995 - 152,902,646 (-)EnsemblGRCm38mm10GRCm38
MGSCv371154,684,125 - 154,749,776 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361154,599,213 - 154,664,840 (-)NCBIMGSCv36mm8
Celera1155,258,082 - 155,323,736 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map165.07NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Aug 31;10(4):167-80.
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073   PMID:18799693  
PMID:21873635   PMID:32325033   PMID:32968282   PMID:33378226   PMID:37349371  


Genomics

Comparative Map Data
Smg7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391152,712,746 - 152,783,212 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1152,712,746 - 152,778,397 (-)EnsemblGRCm39 Ensembl
GRCm381152,836,995 - 152,903,130 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1152,836,995 - 152,902,646 (-)EnsemblGRCm38mm10GRCm38
MGSCv371154,684,125 - 154,749,776 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361154,599,213 - 154,664,840 (-)NCBIMGSCv36mm8
Celera1155,258,082 - 155,323,736 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map165.07NCBI
SMG7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381183,472,499 - 183,554,191 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1183,472,216 - 183,598,246 (+)EnsemblGRCh38hg38GRCh38
GRCh371183,441,634 - 183,523,326 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361181,708,257 - 181,789,949 (+)NCBINCBI36Build 36hg18NCBI36
Build 341180,173,290 - 180,254,982NCBI
Celera1156,552,563 - 156,634,375 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1154,677,519 - 154,759,191 (+)NCBIHuRef
CHM1_11184,864,494 - 184,946,346 (+)NCBICHM1_1
T2T-CHM13v2.01182,831,784 - 182,913,482 (+)NCBIT2T-CHM13v2.0
Smg7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81367,536,016 - 67,600,624 (-)NCBIGRCr8
mRatBN7.21364,986,145 - 65,050,698 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1364,987,434 - 65,050,582 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1367,588,905 - 67,629,946 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01368,875,892 - 68,916,950 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01366,126,955 - 66,168,015 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01370,258,919 - 70,321,886 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1370,258,915 - 70,321,752 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01375,229,500 - 75,292,318 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41367,835,448 - 67,900,289 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11367,849,527 - 67,951,670 (-)NCBI
Celera1364,891,810 - 64,932,829 (-)NCBICelera
Cytogenetic Map13q21NCBI
Smg7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540622,273,298 - 22,352,782 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540622,273,298 - 22,352,782 (+)NCBIChiLan1.0ChiLan1.0
SMG7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2166,163,481 - 66,245,785 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,846,613 - 65,928,939 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01159,002,363 - 159,084,572 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11163,159,294 - 163,242,285 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1163,159,362 - 163,242,285 (+)Ensemblpanpan1.1panPan2
SMG7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1716,820,938 - 16,913,359 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl716,820,882 - 16,911,377 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha716,406,152 - 16,499,070 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0716,552,548 - 16,645,376 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl716,551,996 - 16,645,376 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1716,460,693 - 16,553,547 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0716,570,275 - 16,662,968 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0716,701,145 - 16,793,905 (+)NCBIUU_Cfam_GSD_1.0
Smg7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934488,481,369 - 88,558,329 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364816,326,010 - 6,405,074 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364816,326,211 - 6,405,067 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMG7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9124,697,093 - 124,775,964 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19124,696,432 - 124,775,739 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29137,052,343 - 137,105,730 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SMG7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12545,808,384 - 45,895,605 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2545,805,689 - 45,866,852 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605547,025,227 - 47,114,190 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smg7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462481410,137,548 - 10,224,825 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462481410,135,733 - 10,224,991 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Smg7
2653 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2587
Count of miRNA genes:545
Interacting mature miRNAs:668
Transcripts:ENSMUST00000043560, ENSMUST00000073441, ENSMUST00000111836
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121727729153775746Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121727729153875746Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121727729164827569Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122027729164827569Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1122927738156927738Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128727737181327565Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129130858163130993Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131156308165139464Mouse
14746980Manh50_mmandible shape 50 (mouse)1134131564168131564Mouse
1301458Skts8_mskin tumor susceptibility 8 (mouse)Not determined1135794822169795012Mouse
1301408Lore8_mloss of righting induced by ethanol 8 (mouse)Not determined1135877901169878015Mouse
1357434Obsty1_mobesity 1 (mouse)Not determined1136209950170210094Mouse
4141160Cq1_mcholesterol QTL 1 (mouse)Not determined1139452188173452308Mouse
1301523Ccrs1_mcorpus callosum hemisphere surface size 1 (mouse)Not determined1139602037173602216Mouse
1300696Bpq2_mblood pressure QTL 2 (mouse)Not determined1139602037173602216Mouse
1357602Vtbt2_mvertebral trabecular bone trait 2 (mouse)Not determined1139602037173602216Mouse
1301710Bmd5_mbone mineral density 5 (mouse)Not determined1139602037173602216Mouse
11049576Lmr8a_mleishmaniasis resistance 8a (mouse)1139602037173602216Mouse
1301894Skull2_mskull morphology 2 (mouse)Not determined1139602037173602216Mouse
1302193Cpfd1_mcerebellum pattern fissures (mouse)Not determined1139602037173602216Mouse
1300740Tne1_mtotal number errors (mouse)Not determined1139602037173602216Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141095010175095156Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141233173175233272Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141233173175233272Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141233173175233272Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141233173175233272Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142489543176489734Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143284665177284803Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144449142178449142Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144531347178531592Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145077630179077630Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145145207179145325Mouse
1301818Ap1q_malcohol preference 1 QTL (mouse)Not determined1146908199167586222Mouse
1301135Pas8_mpulmonary adenoma susceptibility 8 (mouse)Not determined1147125258158233272Mouse
1357567Nidd3k_mNidd3 on KK-A<y> (mouse)Not determined7147125258169038913Mouse
12910522Scgq2_mspontaneous crescentic glomerulonephritis QTL 2 (mouse)1147125258171632257Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147125258182873798Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147125258188983224Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147219390181219390Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147219390181219390Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9147875502181875616Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1147875502181875616Mouse
13452392Ity3a_mimmunity to S. typhimurium 3a (mouse)1149028612154228616Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150193673188359312Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150193673188359312Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150193673188359312Mouse
12903996Cfq5_mconditioned fear QTL 5 (mouse)1150606337159307464Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150756737184756922Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151186243185186402Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined151835111185835280Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152038741186038913Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152038741186038913Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152038741186038913Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152038741186038913Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152038741186038913Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152132744186132744Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152132744186132744Mouse

Markers in Region
D1Mit502  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381152,901,644 - 152,901,761UniSTSGRCm38
MGSCv371154,748,774 - 154,748,891UniSTSGRCm37
Celera1155,322,734 - 155,322,851UniSTS
Cytogenetic Map1G3UniSTS
cM Map177.0UniSTS
Whitehead Genetic180.9UniSTS
Whitehead_YAC1 UniSTS
UniSTS:234234  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381152,837,622 - 152,837,826UniSTSGRCm38
MGSCv371154,684,752 - 154,684,956UniSTSGRCm37
Celera1155,258,709 - 155,258,913UniSTS
Cytogenetic Map1G3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001005507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001160256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001160257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK129101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC082789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000043560   ⟹   ENSMUSP00000041241
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,712,747 - 152,753,919 (-)Ensembl
GRCm38.p6 Ensembl1152,836,996 - 152,878,168 (-)Ensembl
RefSeq Acc Id: ENSMUST00000073441   ⟹   ENSMUSP00000073144
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,712,746 - 152,778,373 (-)Ensembl
GRCm38.p6 Ensembl1152,836,995 - 152,902,622 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111836   ⟹   ENSMUSP00000107467
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,714,621 - 152,778,397 (-)Ensembl
GRCm38.p6 Ensembl1152,838,870 - 152,902,646 (-)Ensembl
RefSeq Acc Id: ENSMUST00000186692
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,721,013 - 152,746,909 (-)Ensembl
GRCm38.p6 Ensembl1152,845,262 - 152,871,158 (-)Ensembl
RefSeq Acc Id: ENSMUST00000186900
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,721,035 - 152,724,756 (-)Ensembl
GRCm38.p6 Ensembl1152,845,284 - 152,849,005 (-)Ensembl
RefSeq Acc Id: ENSMUST00000188937
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1152,721,677 - 152,724,671 (-)Ensembl
GRCm38.p6 Ensembl1152,845,926 - 152,848,920 (-)Ensembl
RefSeq Acc Id: NM_001005507   ⟹   NP_001005507
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,746 - 152,778,397 (-)NCBI
GRCm381152,836,995 - 152,902,646 (-)NCBI
MGSCv371154,684,125 - 154,749,776 (-)RGD
Celera1155,258,082 - 155,323,736 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001160256   ⟹   NP_001153728
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,746 - 152,778,397 (-)NCBI
GRCm381152,836,995 - 152,902,646 (-)NCBI
MGSCv371154,684,125 - 154,749,776 (-)RGD
Celera1155,258,082 - 155,323,736 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001160257   ⟹   NP_001153729
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,746 - 152,778,396 (-)NCBI
GRCm381152,836,995 - 152,902,645 (-)NCBI
MGSCv371154,684,125 - 154,749,776 (-)RGD
Celera1155,258,082 - 155,323,736 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001359257   ⟹   NP_001346186
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,746 - 152,778,396 (-)NCBI
GRCm381152,836,995 - 152,902,645 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006529450   ⟹   XP_006529513
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,746 - 152,783,212 (-)NCBI
GRCm381152,836,995 - 152,903,130 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006529451   ⟹   XP_006529514
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,848 - 152,783,212 (-)NCBI
GRCm381152,836,995 - 152,903,130 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253290   ⟹   XP_030109150
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,848 - 152,783,212 (-)NCBI
GRCm381152,836,995 - 152,903,129 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253292   ⟹   XP_030109152
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,848 - 152,783,212 (-)NCBI
GRCm381152,836,995 - 152,903,128 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253294   ⟹   XP_030109154
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,848 - 152,783,212 (-)NCBI
GRCm381152,836,995 - 152,903,128 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253296   ⟹   XP_030109156
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,848 - 152,778,875 (-)NCBI
GRCm381152,836,995 - 152,902,683 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030253298   ⟹   XP_030109158
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,848 - 152,733,196 (-)NCBI
GRCm381152,836,995 - 152,857,452 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036163992   ⟹   XP_036019885
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,848 - 152,778,242 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164011   ⟹   XP_036019904
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,848 - 152,778,875 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164012   ⟹   XP_036019905
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391152,712,848 - 152,778,873 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001005507   ⟸   NM_001005507
- Peptide Label: isoform 3
- UniProtKB: Q5RJH6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001153728   ⟸   NM_001160256
- Peptide Label: isoform 2
- UniProtKB: Q63ZW5 (UniProtKB/Swiss-Prot),   Q6ZQF3 (UniProtKB/Swiss-Prot),   Q5RJH6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001153729   ⟸   NM_001160257
- Peptide Label: isoform 1
- UniProtKB: Q5RJH6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006529514   ⟸   XM_006529451
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006529513   ⟸   XM_006529450
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030109150   ⟸   XM_030253290
- Peptide Label: isoform X4
RefSeq Acc Id: XP_030109154   ⟸   XM_030253294
- Peptide Label: isoform X6
RefSeq Acc Id: XP_030109152   ⟸   XM_030253292
- Peptide Label: isoform X5
RefSeq Acc Id: XP_030109156   ⟸   XM_030253296
- Peptide Label: isoform X7
RefSeq Acc Id: NP_001346186   ⟸   NM_001359257
- Peptide Label: isoform 4
RefSeq Acc Id: XP_030109158   ⟸   XM_030253298
- Peptide Label: isoform X7
RefSeq Acc Id: ENSMUSP00000107467   ⟸   ENSMUST00000111836
RefSeq Acc Id: ENSMUSP00000073144   ⟸   ENSMUST00000073441
RefSeq Acc Id: ENSMUSP00000041241   ⟸   ENSMUST00000043560
RefSeq Acc Id: XP_036019904   ⟸   XM_036164011
- Peptide Label: isoform X7
RefSeq Acc Id: XP_036019905   ⟸   XM_036164012
- Peptide Label: isoform X8
RefSeq Acc Id: XP_036019885   ⟸   XM_036163992
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5RJH6-F1-model_v2 AlphaFold Q5RJH6 1-1138 view protein structure

Promoters
RGD ID:6875252
Promoter ID:EPDNEW_M1077
Type:multiple initiation site
Name:Smg7_1
Description:Mus musculus Smg-7 homolog, nonsense mediated mRNA decay factor, transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381152,902,645 - 152,902,705EPDNEW
RGD ID:6818491
Promoter ID:MM_KWN:2433
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   Brain,   Kidney,   Lung,   MEF_B4,   Spleen
Transcripts:UC007CZO.1,   UC007CZP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361154,749,586 - 154,750,562 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2682334 AgrOrtholog
Ensembl Genes ENSMUSG00000042772 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000043560 ENTREZGENE
  ENSMUST00000043560.15 UniProtKB/Swiss-Prot
  ENSMUST00000073441 ENTREZGENE
  ENSMUST00000073441.13 UniProtKB/Swiss-Prot
  ENSMUST00000111836 ENTREZGENE
  ENSMUST00000111836.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot
InterPro DNA/RNA-bd_Est1-type UniProtKB/Swiss-Prot
  EST1 UniProtKB/Swiss-Prot
  Est1/Ebs1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:226517 UniProtKB/Swiss-Prot
MGD MGI:2682334 ENTREZGENE
NCBI Gene 226517 ENTREZGENE
PANTHER PROTEIN SMG7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15696 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EST1 UniProtKB/Swiss-Prot
  EST1_DNA_bind UniProtKB/Swiss-Prot
PhenoGen Smg7 PhenoGen
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot
UniProt Q3UKQ9_MOUSE UniProtKB/TrEMBL
  Q5RJH6 ENTREZGENE
  Q63ZW5 ENTREZGENE
  Q6ZQF3 ENTREZGENE
  SMG7_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q63ZW5 UniProtKB/Swiss-Prot
  Q6ZQF3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-05-11 Smg7  SMG7 nonsense mediated mRNA decay factor  Smg7  Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)  Symbol and/or name change 5135510 APPROVED