Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | affects expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | Estradiol affects the expression of KIAA1549L mRNA | CTD | PMID:14699072 | 17beta-estradiol | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of KIAA1549L mRNA | CTD | PMID:30165855 | 2-palmitoylglycerol | increases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of KIAA1549L mRNA | CTD | PMID:37199045 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of KIAA1549L mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | KIAA1549L (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of KIAA1549L gene | CTD | PMID:31601247 | acrylamide | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of KIAA1549L mRNA | CTD | PMID:32763439 | aflatoxin B1 | affects methylation | ISO | KIAA1549L (Homo sapiens) | 6480464 | Aflatoxin B1 affects the methylation of KIAA1549L intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | ISO | KIAA1549L (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of KIAA1549L intron | CTD | PMID:30157460 | aristolochic acid A | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of KIAA1549L mRNA | CTD | PMID:33212167 | atrazine | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | Atrazine results in decreased expression of KIAA1549L mRNA | CTD | PMID:22378314 | belinostat | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | belinostat results in decreased expression of KIAA1549L mRNA | CTD | PMID:26272509 | belinostat | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KIAA1549L mRNA | CTD | PMID:27188386 | benzo[a]pyrene | increases methylation | ISO | KIAA1549L (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of KIAA1549L 5' UTR and Benzo(a)pyrene results in increased methylation of KIAA1549L promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | benzo[e]pyrene | increases methylation | ISO | KIAA1549L (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of KIAA1549L intron | CTD | PMID:30157460 | bisphenol A | decreases expression | ISO | D430041D05Rikl (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of KIAA1549L mRNA | CTD | PMID:25181051 | bisphenol A | decreases methylation | ISO | KIAA1549L (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of KIAA1549L gene | CTD | PMID:31601247 | bisphenol F | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of KIAA1549L mRNA | CTD | PMID:28628672 | cadmium atom | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KIAA1549L mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of KIAA1549L mRNA | CTD | PMID:35301059 | cisplatin | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of KIAA1549L mRNA | CTD | PMID:27392435 | cisplatin | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of KIAA1549L mRNA | CTD | PMID:27392435 | dexamethasone | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of KIAA1549L mRNA | CTD | PMID:28628672 | dorsomorphin | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | affects response to substance | ISO | KIAA1549L (Homo sapiens) | 6480464 | KIAA1549L protein affects the susceptibility to Doxorubicin | CTD | PMID:16217747 | FR900359 | increases phosphorylation | ISO | KIAA1549L (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of KIAA1549L protein | CTD | PMID:37730182 | indometacin | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of KIAA1549L mRNA | CTD | PMID:28628672 | methapyrilene | increases methylation | ISO | KIAA1549L (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of KIAA1549L intron | CTD | PMID:30157460 | methylparaben | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | methylparaben results in decreased expression of KIAA1549L mRNA | CTD | PMID:31745603 | PD 0325901 | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | mirdametinib results in decreased expression of KIAA1549L mRNA | CTD | PMID:25119042 | PD 0325901 | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [(+)-JQ1 compound co-treated with mirdametinib] results in decreased expression of KIAA1549L mRNA | CTD | PMID:25119042 | permethrin | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | Permethrin results in decreased expression of KIAA1549L mRNA | CTD | PMID:37047231 | phenylmercury acetate | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of KIAA1549L mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KIAA1549L mRNA | CTD | PMID:27188386 | propanal | increases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of KIAA1549L mRNA | CTD | PMID:26079696 | resveratrol | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of KIAA1549L mRNA | CTD | PMID:23557933 | rotenone | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | Rotenone results in decreased expression of KIAA1549L mRNA | CTD | PMID:29955902 | SB 431542 | multiple interactions | ISO | KIAA1549L (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of KIAA1549L mRNA | CTD | PMID:25895662 | sodium arsenite | increases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of KIAA1549L mRNA | CTD | PMID:34032870 | temozolomide | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of KIAA1549L mRNA | CTD | PMID:31758290 | trichostatin A | increases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | trichostatin A results in increased expression of KIAA1549L mRNA | CTD | PMID:24935251 | triclosan | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | Triclosan results in decreased expression of KIAA1549L mRNA | CTD | PMID:30510588 | valproic acid | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of KIAA1549L mRNA | CTD | PMID:23179753 and PMID:27188386 | vorinostat | decreases expression | ISO | KIAA1549L (Homo sapiens) | 6480464 | vorinostat results in decreased expression of KIAA1549L mRNA | CTD | PMID:27188386 | | 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Gene Ontology Annotations Click to see Annotation Detail View
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Phenotype Annotations
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Mammalian Phenotype
References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Mouse MP Annotation Import Pipeline | RGD automated import pipeline |
| 2. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:7659517 | PMID:8889548 | PMID:10349636 | PMID:10568747 | PMID:11042159 | PMID:11076861 | PMID:11217851 | PMID:11889558 | PMID:12466851 | PMID:12477932 | PMID:16141072 | PMID:16141073 |
| PMID:18799693 | PMID:21267068 |
Genomics
Comparative Map Data
| D430041D05Rik (Mus musculus - house mouse) |
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| KIAA1549L (Homo sapiens - human) |
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| D430041D05Rikl (Rattus norvegicus - Norway rat) |
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| Kiaa1549l (Chinchilla lanigera - long-tailed chinchilla) |
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| KIAA1549L (Pan paniscus - bonobo/pygmy chimpanzee) |
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| KIAA1549L (Canis lupus familiaris - dog) |
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| Kiaa1549l (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| KIAA1549L (Sus scrofa - pig) |
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| KIAA1549L (Chlorocebus sabaeus - green monkey) |
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| Kiaa1549l (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in D430041D05Rik
9374 total Variants 
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