Mettl25 (methyltransferase like 25) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Mettl25 (methyltransferase like 25) Mus musculus
Analyze
Symbol: Mettl25
Name: methyltransferase like 25
RGD ID: 1321072
MGI Page MGI
Description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to act upstream of or within methylation. Is expressed in adrenal gland; ganglia; telencephalon; and testis. Orthologous to human METTL25 (methyltransferase like 25).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC216292; methyltransferase-like protein 25; probable methyltransferase-like protein 25; uncharacterized protein C12orf26 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910105,599,052 - 105,677,246 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10105,599,050 - 105,677,241 (-)EnsemblGRCm39 Ensembl
GRCm3810105,763,185 - 105,841,380 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10105,763,189 - 105,841,380 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710105,200,241 - 105,278,436 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610105,167,357 - 105,245,464 (-)NCBIMGSCv36mm8
Celera10107,712,287 - 107,790,727 (-)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1055.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12520002   PMID:15489334   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21677750  


Genomics

Comparative Map Data
Mettl25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910105,599,052 - 105,677,246 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10105,599,050 - 105,677,241 (-)EnsemblGRCm39 Ensembl
GRCm3810105,763,185 - 105,841,380 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10105,763,189 - 105,841,380 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710105,200,241 - 105,278,436 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610105,167,357 - 105,245,464 (-)NCBIMGSCv36mm8
Celera10107,712,287 - 107,790,727 (-)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1055.12NCBI
METTL25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381282,358,529 - 82,479,239 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1282,358,528 - 82,479,239 (+)EnsemblGRCh38hg38GRCh38
GRCh371282,752,308 - 82,873,018 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361281,276,455 - 81,397,076 (+)NCBINCBI36Build 36hg18NCBI36
Celera1282,419,836 - 82,540,592 (+)NCBICelera
Cytogenetic Map12q21.31NCBI
HuRef1279,809,513 - 79,930,276 (+)NCBIHuRef
CHM1_11282,718,129 - 82,838,893 (+)NCBICHM1_1
T2T-CHM13v2.01282,337,989 - 82,458,720 (+)NCBIT2T-CHM13v2.0
Mettl25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8742,948,934 - 43,029,610 (-)NCBIGRCr8
mRatBN7.2741,062,276 - 41,143,056 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl741,062,276 - 41,143,423 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx742,961,799 - 43,042,744 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0745,164,858 - 45,245,808 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0744,920,977 - 45,000,197 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0747,847,812 - 47,928,495 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl747,847,822 - 47,928,674 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0747,862,494 - 47,942,777 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4744,415,537 - 44,496,537 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1744,435,864 - 44,516,850 (-)NCBI
Celera737,938,606 - 38,019,225 (-)NCBICelera
Cytogenetic Map7q21NCBI
Mettl25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540520,738,842 - 20,822,262 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540520,738,822 - 20,821,256 (+)NCBIChiLan1.0ChiLan1.0
METTL25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21090,402,756 - 90,523,334 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11290,399,087 - 90,519,783 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01279,873,181 - 79,993,799 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11282,981,718 - 83,102,110 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1282,981,718 - 83,102,115 (+)Ensemblpanpan1.1panPan2
METTL25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11524,373,574 - 24,501,226 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1524,373,603 - 24,481,583 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1524,804,479 - 24,932,177 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01524,752,404 - 24,880,103 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1524,752,453 - 24,869,047 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11524,329,749 - 24,457,556 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01524,378,610 - 24,506,344 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01524,619,632 - 24,727,755 (+)NCBIUU_Cfam_GSD_1.0
Mettl25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494535,633,834 - 35,897,488 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936507337,332 - 448,009 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936507337,943 - 448,148 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
METTL25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl599,227,750 - 99,358,587 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1599,216,635 - 99,358,585 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25104,179,077 - 104,213,187 (+)NCBISscrofa10.2Sscrofa10.2susScr3
METTL25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11177,798,362 - 77,934,452 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1177,798,393 - 77,868,464 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037167,467,480 - 167,593,494 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mettl25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248371,693,608 - 1,811,941 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248371,693,562 - 1,811,110 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mettl25
2700 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:740
Count of miRNA genes:422
Interacting mature miRNAs:492
Transcripts:ENSMUST00000046638, ENSMUST00000176040, ENSMUST00000176830, ENSMUST00000176924
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1063935779115935905Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067335830111735905Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073506901107507047Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075338568109338767Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75338568109338767Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075338568109338767Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078381268112381268Mouse
14747004Mancz8_mmandible centroid size 8 (mouse)1082078412116078412Mouse
11059554Lmr32e_mleishmaniasis resistance 32e (mouse)1082309418116309657Mouse
11059555Lmr32f_mleishmaniasis resistance 32f (mouse)1082309418116309657Mouse
11059550Lmr32a_mleishmaniasis resistance 32a (mouse)1082309418116309657Mouse
11059551Lmr32b_mleishmaniasis resistance 32b (mouse)1082309418116309657Mouse
11059553Lmr32d_mleishmaniasis resistance 32d (mouse)1082309418116309657Mouse
1301165Lith7_mlithogenic gene 7 (mouse)Not determined1082309418116309657Mouse
10043881Adip24_madiposity 24 (mouse)Not determined1082392803116392952Mouse
4141054mwfh_mmodifier of white forlock hypopigmentation (mouse)Not determined83017003117017136Mouse
1357594Estoq3_membryo survival total QTL 3 (mouse)Not determined1084079650122041528Mouse
1357622Espq3_membryo survival preimplantation QTL 3 (mouse)Not determined1084079650122041528Mouse
4141479W10q8_mweight 10 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
4142496W6q8_mweight 6 weeks QTL 8 (mouse)Not determined84079650122041528Mouse
4141387Lgaq5_mlate growth adjusted QTL 5 (mouse)Not determined84079650122041528Mouse
4142365Egq9_mearly growth QTL 9 (mouse)Not determined84079650122041528Mouse
1357779Tesq3_mtestis weight QTL 3 (mouse)Not determined1084079650122041528Mouse
1357638Cia29_mcollagen induced arthritis 29 (mouse)Not determined1085454982118497353Mouse
1300797Sluc22_msusceptibility to lung cancer 22 (mouse)Not determined1086713608120713756Mouse
1300908Insq4_minsulin QTL 4 (mouse)Not determined1086909085120909229Mouse
1301520Uvbi1_mUVB induced immunosuppression 1 (mouse)Not determined1086909085120909229Mouse
1300921Skl4_mskeletal size (tail length) 4 (mouse)Not determined1088088254122088391Mouse
4142386Tgq20_mtriglyceride QTL 20 (mouse)Not determined88836456122836456Mouse
1301758Fcsa3_mfemoral cross-sectional area 3 (mouse)Not determined1089927651123927754Mouse
11039516Ltpr5_mLeishmania tropica response 5 (mouse)1090506901125575232Mouse
13208554Lgth11_mbody length 11 (mouse)1090835862120835905Mouse
12910821Ogrq4_moverall growth rate QTL 4 (mouse)1092169056107319989Mouse
4142074Tmevp2_mTheiler's murine encephalomyelitis virus persistence 2 (mouse)Not determined92729941111568319Mouse
1357544Vtbt10_mvertebral trabecular bone trait 10 (mouse)Not determined1097217101130530862Mouse
4142461Bmd25_mbone mineral density 25 (mouse)Not determined1097217101130530862Mouse
11533919Mvb4_mmodifier of vibrator 4 (mouse)397217101130530862Mouse
11533921Mvb2_mmodifier of vibrator 2 (mouse)1097217101130530862Mouse
12880413V125Dq9_mvitamin D active form serum level QTL 9 (mouse)1097535905130530862Mouse
4141402T2dm1sa_mtype 2 diabetes mellitus 1 in SMXA RI mice (mouse)Not determined97758644130530862Mouse
11040593Lmr5e_mleishmaniasis resistance 5e (mouse)1099220635130530862Mouse
11040595Lmr5c_mleishmaniasis resistance 5c (mouse)1099220635130530862Mouse
11040597Lmr5a_mleishmaniasis resistance 5a (mouse)1099220635130530862Mouse
11059552Lmr32c_mleishmaniasis resistance 32c (mouse)1099309418116220862Mouse
11059544Lmr32_mleishmaniasis resistance 32 (mouse)1099309418116220862Mouse
1357744Cfbw4_mcystic fibrosis body weight 4 (mouse)Not determined10100986516130530862Mouse
1301968Estq4_mestradiol regulated response QTL 4 (mouse)Not determined10100986516130530862Mouse
1301901Im5_mimmunoregulatory 5 (mouse)Not determined10101497164130530862Mouse
4141361Cfmq3_mcystic fibrosis modifier QTL 3 (mouse)Not determined10101497164130530862Mouse
26884388Skwq7_mskull length QTL 7, 10 week (mouse)10101735861113735905Mouse
1300678Leg2_mlongevity extending gene 2 (mouse)Not determined10102506908130530862Mouse
27226725Tibw1_mtibia width 1, proximal, 5 week (mouse)10102735861123235905Mouse
1301895Exq1_mexploratory and excitability QTL 1 (mouse)Not determined10102847852130530862Mouse
14696727Kidrq2_mkidney weight, right QTL 2 (mouse)10102902508130530862Mouse
4141007Obrq10_mobesity resistance QTL 10 (mouse)Not determined103243727130530862Mouse
4141487Tgq21_mtriglyceride QTL 21 (mouse)Not determined104110021130530862Mouse
14746996Manh69_mmandible shape 69 (mouse)10104763638130530862Mouse
1302200Sle12_msystematic lupus erythematosus susceptibility 12 (mouse)Not determined10105041304130530862Mouse
1357482Nhdlq4_mnon-HDL QTL 4 (mouse)Not determined10105041304130530862Mouse
1300679Nociq2_mnociceptive sensitivity inflammatory QTL 2 (mouse)Not determined10105041304130530862Mouse
4141269Ipng2_mimprinted postnatal growth 2 (mouse)Not determined105088254118497353Mouse
11040594Lmr5f_mleishmaniasis resistance 5f (mouse)10105179713130530862Mouse
11040596Lmr5d_mleishmaniasis resistance 5d (mouse)10105179713130530862Mouse
11040598Lmr5b_mleishmaniasis resistance 5b (mouse)10105179713130530862Mouse

Markers in Region
D10Wsu1e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810105,839,409 - 105,839,578UniSTSGRCm38
MGSCv3710105,276,465 - 105,276,634UniSTSGRCm37
Celera10107,788,756 - 107,788,925UniSTS
Cytogenetic Map10D1UniSTS
cM Map1059.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001359640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_207522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001779503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001779504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003948672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003948673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_871709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_871710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC125108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV286383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB345676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC067068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK618051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000046638   ⟹   ENSMUSP00000038665
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10105,599,050 - 105,677,239 (-)Ensembl
GRCm38.p6 Ensembl10105,763,189 - 105,841,378 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176040   ⟹   ENSMUSP00000135255
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10105,662,434 - 105,677,232 (-)Ensembl
GRCm38.p6 Ensembl10105,826,573 - 105,841,371 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10105,675,066 - 105,677,072 (-)Ensembl
GRCm38.p6 Ensembl10105,839,205 - 105,841,211 (-)Ensembl
RefSeq Acc Id: ENSMUST00000176924   ⟹   ENSMUSP00000134888
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10105,599,116 - 105,677,241 (-)Ensembl
GRCm38.p6 Ensembl10105,763,255 - 105,841,380 (-)Ensembl
RefSeq Acc Id: NM_001359640   ⟹   NP_001346569
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,052 - 105,677,241 (-)NCBI
GRCm3810105,763,191 - 105,841,380 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359642   ⟹   NP_001346571
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,052 - 105,677,241 (-)NCBI
GRCm3810105,763,191 - 105,841,380 (-)NCBI
Sequence:
RefSeq Acc Id: NM_207522   ⟹   NP_997405
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,054 - 105,677,208 (-)NCBI
GRCm3810105,763,185 - 105,841,380 (-)ENTREZGENE
MGSCv3710105,200,241 - 105,278,436 (-)RGD
Celera10107,712,287 - 107,790,727 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011243411   ⟹   XP_011241713
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,235 (-)NCBI
GRCm3810105,763,247 - 105,841,374 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243412   ⟹   XP_011241714
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,235 (-)NCBI
GRCm3810105,763,247 - 105,841,374 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243414   ⟹   XP_011241716
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,221 (-)NCBI
GRCm3810105,763,247 - 105,841,327 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313903   ⟹   XP_017169392
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,052 - 105,677,235 (-)NCBI
GRCm3810105,763,191 - 105,841,374 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313904   ⟹   XP_017169393
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,019 (-)NCBI
GRCm3810105,763,247 - 105,841,158 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245031   ⟹   XP_030100891
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,239 (-)NCBI
GRCm3810105,763,247 - 105,841,378 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245032   ⟹   XP_030100892
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,239 (-)NCBI
GRCm3810105,763,247 - 105,841,378 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245033   ⟹   XP_030100893
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,239 (-)NCBI
GRCm3810105,763,247 - 105,841,378 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245035   ⟹   XP_030100895
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,025 (-)NCBI
GRCm3810105,763,247 - 105,841,164 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245037   ⟹   XP_030100897
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,052 - 105,677,239 (-)NCBI
GRCm3810105,763,191 - 105,841,378 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245038   ⟹   XP_030100898
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,052 - 105,677,246 (-)NCBI
GRCm3810105,763,191 - 105,841,336 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245039   ⟹   XP_030100899
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,052 - 105,677,222 (-)NCBI
GRCm3810105,763,191 - 105,841,361 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036155755   ⟹   XP_036011648
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,022 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036155756   ⟹   XP_036011649
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,025 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036155757   ⟹   XP_036011650
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,052 - 105,676,773 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001779503
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,235 (-)NCBI
GRCm3810105,763,247 - 105,841,374 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001779504
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,235 (-)NCBI
GRCm3810105,763,247 - 105,841,374 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003948672
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,235 (-)NCBI
GRCm3810105,763,247 - 105,841,374 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003948673
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,633,092 - 105,677,235 (-)NCBI
GRCm3810105,797,231 - 105,841,374 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004936161
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,235 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004936162
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,235 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004936163
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,235 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004936164
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,601,825 - 105,677,235 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004936165
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,599,108 - 105,677,226 (-)NCBI
Sequence:
RefSeq Acc Id: XR_871709
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,633,092 - 105,677,235 (-)NCBI
GRCm3810105,797,231 - 105,841,374 (-)NCBI
Sequence:
RefSeq Acc Id: XR_871710
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910105,633,091 - 105,677,235 (-)NCBI
GRCm3810105,797,230 - 105,841,374 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_997405   ⟸   NM_207522
- Peptide Label: isoform 1
- UniProtKB: A0A0R4J0G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241714   ⟸   XM_011243412
- Peptide Label: isoform X2
- UniProtKB: Q6NXH8 (UniProtKB/Swiss-Prot),   Q3UMX5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011241713   ⟸   XM_011243411
- Peptide Label: isoform X1
- UniProtKB: Q6NXH8 (UniProtKB/Swiss-Prot),   Q3UMX5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011241716   ⟸   XM_011243414
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017169392   ⟸   XM_017313903
- Peptide Label: isoform X3
- UniProtKB: Q6NXH8 (UniProtKB/Swiss-Prot),   Q3UMX5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017169393   ⟸   XM_017313904
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001346571   ⟸   NM_001359642
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001346569   ⟸   NM_001359640
- Peptide Label: isoform 2
RefSeq Acc Id: XP_030100897   ⟸   XM_030245037
- Peptide Label: isoform X6
RefSeq Acc Id: XP_030100899   ⟸   XM_030245039
- Peptide Label: isoform X7
RefSeq Acc Id: XP_030100898   ⟸   XM_030245038
- Peptide Label: isoform X6
RefSeq Acc Id: XP_030100891   ⟸   XM_030245031
- Peptide Label: isoform X4
RefSeq Acc Id: XP_030100893   ⟸   XM_030245033
- Peptide Label: isoform X4
RefSeq Acc Id: XP_030100892   ⟸   XM_030245032
- Peptide Label: isoform X4
RefSeq Acc Id: XP_030100895   ⟸   XM_030245035
- Peptide Label: isoform X5
RefSeq Acc Id: ENSMUSP00000038665   ⟸   ENSMUST00000046638
RefSeq Acc Id: ENSMUSP00000134888   ⟸   ENSMUST00000176924
RefSeq Acc Id: ENSMUSP00000135255   ⟸   ENSMUST00000176040
RefSeq Acc Id: XP_036011650   ⟸   XM_036155757
- Peptide Label: isoform X6
RefSeq Acc Id: XP_036011649   ⟸   XM_036155756
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036011648   ⟸   XM_036155755
- Peptide Label: isoform X4
Protein Domains
Methyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6NXH8-F1-model_v2 AlphaFold Q6NXH8 1-597 view protein structure

Promoters
RGD ID:6819048
Promoter ID:MM_KWN:5554
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day4,   BoneMarrow_2Hour,   Brain,   Liver,   MEF_B4,   Spleen
Transcripts:NM_207522
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610105,278,079 - 105,278,579 (-)MPROMDB
RGD ID:8673200
Promoter ID:EPDNEW_M14631
Type:multiple initiation site
Name:Mettl25_1
Description:Mus musculus methyltransferase like 25 , transcript variant 3,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3810105,841,347 - 105,841,407EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3041259 AgrOrtholog
Ensembl Genes ENSMUSG00000036009 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000046638 ENTREZGENE
  ENSMUST00000046638.10 UniProtKB/TrEMBL
  ENSMUST00000176040.2 UniProtKB/TrEMBL
  ENSMUST00000176924 ENTREZGENE
  ENSMUST00000176924.8 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Methyltranfer_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:216292 UniProtKB/Swiss-Prot
MGD MGI:3041259 ENTREZGENE
NCBI Gene 216292 ENTREZGENE
PANTHER CGI-41 METHYLTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  METHYLTRANSFERASE-LIKE PROTEIN 25-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Methyltransf_32 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mettl25 PhenoGen
Superfamily-SCOP SSF53335 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J0G2 ENTREZGENE, UniProtKB/TrEMBL
  H3BJ85_MOUSE UniProtKB/TrEMBL
  H3BK52_MOUSE UniProtKB/TrEMBL
  MET25_MOUSE UniProtKB/Swiss-Prot
  Q3UMX5 ENTREZGENE
  Q6NXH8 ENTREZGENE
UniProt Secondary Q3UMX5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-11-20 Mettl25  methyltransferase like 25  BC067068  cDNA sequence BC067068  Symbol and/or name change 5135510 APPROVED