Sim1 (single-minded family bHLH transcription factor 1) - Rat Genome Database

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Gene: Sim1 (single-minded family bHLH transcription factor 1) Mus musculus
Analyze
Symbol: Sim1
Name: single-minded family bHLH transcription factor 1
RGD ID: 1320568
MGI Page MGI
Description: Enables protein heterodimerization activity. Involved in ureteric bud development. Acts upstream of or within regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; future brain; genitourinary system; and sensory organ. Used to study obesity. Human ortholog(s) of this gene implicated in obesity. Orthologous to human SIM1 (SIM bHLH transcription factor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bHLHe1; bHLHe14; mSIM1; single-minded 1; single-minded homolog 1; single-minded homolog 1 (Drosophila)
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391050,770,794 - 50,865,252 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1050,770,850 - 50,865,248 (+)EnsemblGRCm39 Ensembl
GRCm381050,894,698 - 50,989,156 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1050,894,754 - 50,989,152 (+)EnsemblGRCm38mm10GRCm38
MGSCv371050,615,457 - 50,708,958 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361050,584,066 - 50,677,567 (+)NCBIMGSCv36mm8
Celera1051,744,683 - 51,838,475 (+)NCBICelera
Cytogenetic Map10B3NCBI
cM Map1024.87NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IDA)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Profound obesity associated with a balanced translocation that disrupts the SIM1 gene. Holder JL Jr, etal., Hum Mol Genet. 2000 Jan 1;9(1):101-8.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7485157   PMID:8221886   PMID:8561800   PMID:8631247   PMID:8661115   PMID:8812055   PMID:8875433   PMID:8927054   PMID:9020169   PMID:9199929   PMID:9199934   PMID:9230312  
PMID:9510020   PMID:9585504   PMID:9655799   PMID:9784500   PMID:9811581   PMID:10217145   PMID:10457014   PMID:10557207   PMID:10575223   PMID:10603349   PMID:10640708   PMID:10837894  
PMID:11023872   PMID:11071765   PMID:11381139   PMID:11448938   PMID:11455436   PMID:11566099   PMID:11782478   PMID:11830575   PMID:11955448   PMID:12024028   PMID:12086465   PMID:12490199  
PMID:12571110   PMID:12948657   PMID:14602680   PMID:14660629   PMID:14678827   PMID:14681479   PMID:14982752   PMID:14988428   PMID:15075292   PMID:15134635   PMID:15162501   PMID:15496443  
PMID:15576403   PMID:15604102   PMID:15618518   PMID:15629702   PMID:15649943   PMID:15789444   PMID:15976074   PMID:16269339   PMID:16284245   PMID:16291793   PMID:16319112   PMID:16357211  
PMID:16545622   PMID:16602821   PMID:16728530   PMID:16807340   PMID:16860307   PMID:16951257   PMID:17356169   PMID:17611227   PMID:17826745   PMID:18056790   PMID:18162531   PMID:18287559  
PMID:18451093   PMID:18557763   PMID:18617019   PMID:18817733   PMID:18940590   PMID:19123137   PMID:19386638   PMID:19474326   PMID:19521566   PMID:19666821   PMID:20035737   PMID:20059953  
PMID:20092566   PMID:20092567   PMID:20211142   PMID:20220015   PMID:20436479   PMID:20460368   PMID:20495559   PMID:21048120   PMID:21062862   PMID:21068056   PMID:21211521   PMID:21239438  
PMID:21267068   PMID:21525287   PMID:21541283   PMID:21689430   PMID:21752929   PMID:21873635   PMID:22264356   PMID:22558467   PMID:22988430   PMID:23595746   PMID:23988635   PMID:24259577  
PMID:24260538   PMID:24485459   PMID:24514266   PMID:24698273   PMID:24773343   PMID:24952961   PMID:25392491   PMID:25392496   PMID:25456065   PMID:25607894   PMID:25652362   PMID:25864637  
PMID:26187199   PMID:26460719   PMID:26680198   PMID:26839365   PMID:27209204   PMID:27782878   PMID:27806288   PMID:27866798   PMID:28195039   PMID:28262664   PMID:28706241   PMID:28807781  
PMID:28916788   PMID:29059347   PMID:29679559   PMID:30063881   PMID:30177510   PMID:30282024   PMID:30545847   PMID:30802281   PMID:30879785   PMID:31291587   PMID:31336385   PMID:31427287  
PMID:31824266   PMID:31826942   PMID:32325033   PMID:33298461   PMID:33492553   PMID:33591268   PMID:33887179   PMID:34095148   PMID:34321664   PMID:34705510   PMID:35476640   PMID:37081156  
PMID:37364986  


Genomics

Comparative Map Data
Sim1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391050,770,794 - 50,865,252 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1050,770,850 - 50,865,248 (+)EnsemblGRCm39 Ensembl
GRCm381050,894,698 - 50,989,156 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1050,894,754 - 50,989,152 (+)EnsemblGRCm38mm10GRCm38
MGSCv371050,615,457 - 50,708,958 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361050,584,066 - 50,677,567 (+)NCBIMGSCv36mm8
Celera1051,744,683 - 51,838,475 (+)NCBICelera
Cytogenetic Map10B3NCBI
cM Map1024.87NCBI
SIM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386100,385,009 - 100,464,921 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6100,385,009 - 100,464,921 (-)EnsemblGRCh38hg38GRCh38
GRCh376100,832,885 - 100,912,797 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366100,943,471 - 101,018,272 (-)NCBINCBI36Build 36hg18NCBI36
Build 346100,943,470 - 101,018,272NCBI
Celera6101,480,981 - 101,555,761 (-)NCBICelera
Cytogenetic Map6q16.3NCBI
HuRef698,275,663 - 98,350,456 (-)NCBIHuRef
CHM1_16101,098,793 - 101,173,570 (-)NCBICHM1_1
T2T-CHM13v2.06101,558,767 - 101,638,670 (-)NCBIT2T-CHM13v2.0
Sim1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82055,409,814 - 55,489,450 (+)NCBIGRCr8
mRatBN7.22053,827,601 - 53,907,219 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2053,828,364 - 53,907,212 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2055,543,215 - 55,626,456 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02055,192,931 - 55,276,173 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02055,885,015 - 55,963,896 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02055,590,810 - 55,674,002 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2055,594,676 - 55,673,995 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02057,192,734 - 57,274,564 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42054,908,178 - 54,988,099 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12054,937,202 - 55,012,573 (+)NCBI
Celera2046,257,466 - 46,336,238 (-)NCBICelera
Cytogenetic Map20q13NCBI
Sim1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541126,173,009 - 26,259,752 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541126,173,009 - 26,256,545 (-)NCBIChiLan1.0ChiLan1.0
SIM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25120,431,444 - 120,506,816 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16118,308,628 - 118,388,705 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0698,221,476 - 98,301,215 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16102,104,462 - 102,181,062 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6102,104,783 - 102,181,062 (-)Ensemblpanpan1.1panPan2
SIM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11258,480,744 - 58,552,126 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1258,485,823 - 58,553,192 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1258,239,464 - 58,312,667 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01259,313,324 - 59,386,528 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1259,319,037 - 59,386,575 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11258,666,215 - 58,739,215 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01258,507,210 - 58,580,362 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01258,747,572 - 58,820,839 (-)NCBIUU_Cfam_GSD_1.0
Sim1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494693,381,896 - 93,456,539 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366511,841,054 - 1,911,944 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366511,841,040 - 1,911,944 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SIM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl167,214,337 - 67,294,397 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1167,213,685 - 67,294,455 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2176,000,269 - 76,071,230 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SIM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11373,451,838 - 73,527,733 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1373,453,800 - 73,527,198 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604045,749,767 - 45,824,784 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sim1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248104,479,589 - 4,558,434 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248104,479,589 - 4,558,735 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sim1
2257 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1421
Count of miRNA genes:617
Interacting mature miRNAs:799
Transcripts:ENSMUST00000020071
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302092Ath11_matherosclerosis 11 (mouse)Not determined10615194558693521Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
10755518Chol16_mcholesterol 16 (mouse)101891504352915043Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102028318556031223Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102159119268091639Mouse
26884394Humsd3_mhumerus midshaft diameter 3, 10 week (mouse)102237589951076096Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
1300898Cfid_mcystic fibrosis intestinal distress (mouse)Not determined102972040363720483Mouse
10045632Heal16_mwound healing/regeneration 16 (mouse)Not determined103097449964974630Mouse
1357558Bmch4_mbone mechanical trait 4 (mouse)Not determined103157713665577284Mouse
27095920Pglq9_mpelvic girdle length QTL 9, 10 week (mouse)103377599670835830Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
21079434Bdym5_mbody mass QTL 5 (mouse)104054599654836096Mouse
4141070Ltgq1_mliver triglyceride QTL 1 (mouse)Not determined4123732675237326Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
26884421Cvht5_mcranial vault height 5, 10 week (mouse)104557609669135830Mouse
14697707Stsl2_mSalmonella typhimurium susceptibility locus 2 (mouse)104627609653876096Mouse
26884400Huml5_mhumerus length 5, 16 week (mouse)104627609669235830Mouse
4142313Angvq1_mangiogenesis by VEGF QTL 1 (mouse)Not determined4672040382491121Mouse
4141159Phl2_mprogressive hearing loss 2 (mouse)Not determined104797449970112651Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104933801283338157Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined104984818783848412Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined104984818783848412Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined104984818783848412Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined104984822283848397Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined104984822283848397Mouse

Markers in Region
Sim1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10B3UniSTS
cM Map1026.5UniSTS
cM Map1026.5UniSTS
UniSTS:236348  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381050,987,962 - 50,988,162UniSTSGRCm38
MGSCv371050,707,768 - 50,707,968UniSTSGRCm37
Celera1051,837,285 - 51,837,485UniSTS
Cytogenetic Map10B3UniSTS
cM Map1026.5UniSTS
PMC317216P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381050,895,350 - 50,895,637UniSTSGRCm38
MGSCv371050,615,156 - 50,615,443UniSTSGRCm37
Celera1051,744,382 - 51,744,669UniSTS
Cytogenetic Map10B3UniSTS
cM Map1026.5UniSTS
Sim1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10B3UniSTS
cM Map1026.5UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000020071   ⟹   ENSMUSP00000020071
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1050,771,747 - 50,865,248 (+)Ensembl
GRCm38.p6 Ensembl1050,895,651 - 50,989,152 (+)Ensembl
RefSeq Acc Id: ENSMUST00000219436   ⟹   ENSMUSP00000151816
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1050,770,850 - 50,776,094 (+)Ensembl
GRCm38.p6 Ensembl1050,894,754 - 50,899,998 (+)Ensembl
RefSeq Acc Id: NM_011376   ⟹   NP_035506
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391050,771,747 - 50,865,248 (+)NCBI
GRCm381050,895,651 - 50,989,152 (+)NCBI
MGSCv371050,615,457 - 50,708,958 (+)RGD
Celera1051,744,683 - 51,838,475 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006512626   ⟹   XP_006512689
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391050,770,794 - 50,865,252 (+)NCBI
GRCm381050,894,698 - 50,989,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006512627   ⟹   XP_006512690
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391050,770,794 - 50,865,252 (+)NCBI
GRCm381050,894,698 - 50,989,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006512630   ⟹   XP_006512693
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391050,784,036 - 50,865,252 (+)NCBI
GRCm381050,907,940 - 50,989,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006512631   ⟹   XP_006512694
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391050,784,612 - 50,865,252 (+)NCBI
GRCm381050,908,516 - 50,989,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006512632   ⟹   XP_006512695
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391050,770,794 - 50,798,130 (+)NCBI
GRCm381050,894,698 - 50,922,034 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_035506   ⟸   NM_011376
- UniProtKB: O70284 (UniProtKB/Swiss-Prot),   P70183 (UniProtKB/Swiss-Prot),   Q61045 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006512689   ⟸   XM_006512626
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006512690   ⟸   XM_006512627
- Peptide Label: isoform X2
- UniProtKB: O70284 (UniProtKB/Swiss-Prot),   P70183 (UniProtKB/Swiss-Prot),   Q61045 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006512695   ⟸   XM_006512632
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006512693   ⟸   XM_006512630
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006512694   ⟸   XM_006512631
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSMUSP00000020071   ⟸   ENSMUST00000020071
RefSeq Acc Id: ENSMUSP00000151816   ⟸   ENSMUST00000219436
Protein Domains
bHLH   PAC   PAS   Single-minded C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61045-F1-model_v2 AlphaFold Q61045 1-765 view protein structure

Promoters
RGD ID:6819911
Promoter ID:MM_KWN:4107
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:NM_011376
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361050,614,551 - 50,615,707 (+)MPROMDB
RGD ID:8671944
Promoter ID:EPDNEW_M14003
Type:single initiation site
Name:Sim1_1
Description:Mus musculus single-minded family bHLH transcription factor 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381050,895,749 - 50,895,809EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98306 AgrOrtholog
Ensembl Genes ENSMUSG00000019913 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020071 ENTREZGENE
  ENSMUST00000020071.4 UniProtKB/Swiss-Prot
  ENSMUST00000219436.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS domain UniProtKB/Swiss-Prot
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAC UniProtKB/Swiss-Prot
  PAS UniProtKB/Swiss-Prot
  PAS-like_dom_sf UniProtKB/Swiss-Prot
  PAS_fold UniProtKB/Swiss-Prot
  PAS_fold_3 UniProtKB/Swiss-Prot
  SIM_C UniProtKB/Swiss-Prot
KEGG Report mmu:20464 UniProtKB/Swiss-Prot
MGD MGI:98306 ENTREZGENE
NCBI Gene 20464 ENTREZGENE
PANTHER HYPOXIA-INDUCIBLE FACTOR 1 ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SINGLE-MINDED HOMOLOG 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS UniProtKB/Swiss-Prot
  PAS_3 UniProtKB/Swiss-Prot
  SIM_C UniProtKB/Swiss-Prot
PhenoGen Sim1 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAS UniProtKB/Swiss-Prot
  SIM_C UniProtKB/Swiss-Prot
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAC UniProtKB/Swiss-Prot
  PAS UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55785 UniProtKB/Swiss-Prot
UniProt A0A1W2P7V8_MOUSE UniProtKB/TrEMBL
  O70284 ENTREZGENE
  P70183 ENTREZGENE
  Q61045 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O70284 UniProtKB/Swiss-Prot
  P70183 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-31 Sim1  single-minded family bHLH transcription factor 1    single-minded homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED