GTF3C3 (general transcription factor IIIC subunit 3) - Rat Genome Database

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Gene: GTF3C3 (general transcription factor IIIC subunit 3) Homo sapiens
Analyze
Symbol: GTF3C3
Name: general transcription factor IIIC subunit 3
RGD ID: 1319385
HGNC Page HGNC:4666
Description: Enables RNA polymerase III general transcription initiation factor activity. Predicted to be involved in transcription by RNA polymerase III. Located in fibrillar center; nuclear membrane; and nucleoplasm. Part of transcription factor TFIIIC complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: general transcription factor 3C polypeptide 3; general transcription factor IIIC, polypeptide 3, 102kDa; TF3C-gamma; TFIIIC 102 kDa subunit; TFIIIC102; TFiiiC2-102; TFIIICgamma; transcription factor IIIC 102 kDa subunit; transcription factor IIIC subunit gamma; transcription factor IIIC, 102 kD
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382196,763,035 - 196,799,683 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2196,763,035 - 196,799,725 (-)EnsemblGRCh38hg38GRCh38
GRCh372197,627,759 - 197,664,407 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362197,337,345 - 197,372,670 (-)NCBINCBI36Build 36hg18NCBI36
Build 342197,454,606 - 197,489,931NCBI
Celera2191,384,968 - 191,420,293 (-)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2189,480,345 - 189,517,101 (-)NCBIHuRef
CHM1_12197,633,622 - 197,670,344 (-)NCBICHM1_1
T2T-CHM13v2.02197,246,743 - 197,283,354 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. A structural perspective on RNA polymerase I and RNA polymerase III transcription machineries. Vannini A Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):258-64. doi: 10.1016/j.bbagrm.2012.09.009. Epub 2012 Sep 29.
Additional References at PubMed
PMID:1403646   PMID:7729686   PMID:8573604   PMID:10373544   PMID:10523658   PMID:11965497   PMID:12477932   PMID:14702039   PMID:15231747   PMID:15489334   PMID:16344560   PMID:17314511  
PMID:17353931   PMID:17409385   PMID:17500595   PMID:17643375   PMID:18644873   PMID:18976975   PMID:19521658   PMID:19596235   PMID:20211142   PMID:20360068   PMID:20562859   PMID:21549307  
PMID:21873635   PMID:22586326   PMID:22939629   PMID:23275444   PMID:23383273   PMID:23443559   PMID:24457600   PMID:25437307   PMID:25609649   PMID:25921289   PMID:26186194   PMID:26299517  
PMID:26344197   PMID:26496610   PMID:26638075   PMID:26673895   PMID:26687479   PMID:26972000   PMID:27248496   PMID:27545878   PMID:27634302   PMID:28077445   PMID:28242625   PMID:28380382  
PMID:28514442   PMID:29180619   PMID:29229926   PMID:29378950   PMID:29467282   PMID:29507755   PMID:29509190   PMID:29564676   PMID:29568061   PMID:29656893   PMID:29802200   PMID:29844126  
PMID:29991511   PMID:30033366   PMID:30154076   PMID:30415952   PMID:30554943   PMID:30940648   PMID:30948266   PMID:31010829   PMID:31059266   PMID:31073040   PMID:31091453   PMID:31665637  
PMID:31685992   PMID:32129710   PMID:32416067   PMID:32707033   PMID:32807901   PMID:32814053   PMID:32891193   PMID:33239621   PMID:33306668   PMID:33658012   PMID:33665565   PMID:33711283  
PMID:33729478   PMID:33957083   PMID:33961781   PMID:34079125   PMID:34244565   PMID:34373451   PMID:34780483   PMID:35013218   PMID:35013556   PMID:35032548   PMID:35140242   PMID:35271311  
PMID:35439318   PMID:35446349   PMID:35509820   PMID:35563538   PMID:35696571   PMID:35831314   PMID:35844135   PMID:35850772   PMID:35944360   PMID:36089195   PMID:36215168   PMID:36244648  
PMID:36339263   PMID:36424410   PMID:36526897   PMID:36880596   PMID:36912080   PMID:37827155   PMID:38113892   PMID:38270169   PMID:38280479  


Genomics

Comparative Map Data
GTF3C3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382196,763,035 - 196,799,683 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2196,763,035 - 196,799,725 (-)EnsemblGRCh38hg38GRCh38
GRCh372197,627,759 - 197,664,407 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362197,337,345 - 197,372,670 (-)NCBINCBI36Build 36hg18NCBI36
Build 342197,454,606 - 197,489,931NCBI
Celera2191,384,968 - 191,420,293 (-)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2189,480,345 - 189,517,101 (-)NCBIHuRef
CHM1_12197,633,622 - 197,670,344 (-)NCBICHM1_1
T2T-CHM13v2.02197,246,743 - 197,283,354 (-)NCBIT2T-CHM13v2.0
Gtf3c3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39154,435,036 - 54,478,185 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl154,435,163 - 54,478,130 (-)EnsemblGRCm39 Ensembl
GRCm38154,395,877 - 54,439,026 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl154,396,004 - 54,438,971 (-)EnsemblGRCm38mm10GRCm38
MGSCv37154,454,425 - 54,495,815 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36154,342,126 - 54,383,516 (-)NCBIMGSCv36mm8
Celera154,929,203 - 54,963,747 (-)NCBICelera
Cytogenetic Map1C1.2NCBI
cM Map127.13NCBI
Gtf3c3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8963,375,860 - 63,437,475 (-)NCBIGRCr8
mRatBN7.2955,882,252 - 55,943,037 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl955,883,721 - 55,942,967 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx964,426,072 - 64,459,745 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0969,541,876 - 69,575,649 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0967,833,711 - 67,867,576 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0960,999,159 - 61,033,612 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl960,969,061 - 61,033,580 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0960,655,632 - 60,717,672 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4953,186,285 - 53,219,830 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1953,188,492 - 53,221,200 (-)NCBI
Celera953,399,209 - 53,432,756 (-)NCBICelera
Cytogenetic Map9q31NCBI
Gtf3c3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554033,610,913 - 3,641,340 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554033,610,938 - 3,637,893 (+)NCBIChiLan1.0ChiLan1.0
GTF3C3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21399,383,854 - 99,419,683 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B99,398,845 - 99,434,698 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B84,007,630 - 84,043,700 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B201,906,048 - 201,941,725 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B201,906,665 - 201,941,538 (-)Ensemblpanpan1.1panPan2
GTF3C3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1376,360,072 - 6,397,959 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl376,359,568 - 6,397,932 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha377,307,403 - 7,345,412 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0376,249,800 - 6,288,042 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl376,249,804 - 6,287,999 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1376,249,442 - 6,287,648 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0376,216,216 - 6,255,042 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0376,238,434 - 6,276,800 (-)NCBIUU_Cfam_GSD_1.0
Gtf3c3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303154,453,144 - 154,497,540 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365062,340,443 - 2,385,461 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365062,340,443 - 2,384,330 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTF3C3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15100,667,323 - 100,701,664 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115100,667,312 - 100,701,705 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215111,727,846 - 111,761,129 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GTF3C3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11082,288,845 - 82,323,768 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1082,287,880 - 82,323,716 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040117,132,984 - 117,167,886 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gtf3c3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624854333,602 - 360,994 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624854333,507 - 362,324 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GTF3C3
16 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q31.1-33.2(chr2:174898848-203941548)x1 copy number loss See cases [RCV000050980] Chr2:174898848..203941548 [GRCh38]
Chr2:175763576..204806271 [GRCh37]
Chr2:175471822..204514516 [NCBI36]
Chr2:2q31.1-33.2		 pathogenic
GRCh38/hg38 2q32.3-33.1(chr2:194515159-198545937)x1 copy number loss See cases [RCV000051092] Chr2:194515159..198545937 [GRCh38]
Chr2:195379883..199410661 [GRCh37]
Chr2:195088128..199118906 [NCBI36]
Chr2:2q32.3-33.1		 pathogenic
GRCh38/hg38 2q32.3-37.3(chr2:194898783-236473913)x3 copy number gain See cases [RCV000051119] Chr2:194898783..236473913 [GRCh38]
Chr2:195763507..237382556 [GRCh37]
Chr2:195471752..237047295 [NCBI36]
Chr2:2q32.3-37.3		 pathogenic
GRCh38/hg38 2q31.1-33.1(chr2:176304445-202039790)x1 copy number loss See cases [RCV000052558] Chr2:176304445..202039790 [GRCh38]
Chr2:177169173..202904513 [GRCh37]
Chr2:176877419..202612758 [NCBI36]
Chr2:2q31.1-33.1		 pathogenic
GRCh38/hg38 2q31.2-33.1(chr2:177874070-198525492)x1 copy number loss See cases [RCV000052559] Chr2:177874070..198525492 [GRCh38]
Chr2:178738797..199390216 [GRCh37]
Chr2:178447043..199098461 [NCBI36]
Chr2:2q31.2-33.1		 pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:188818195-242065208)x3 copy number gain See cases [RCV000052958] Chr2:188818195..242065208 [GRCh38]
Chr2:189682921..243007359 [GRCh37]
Chr2:189391166..242656032 [NCBI36]
Chr2:2q32.2-37.3		 pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:190310736-241892770)x3 copy number gain See cases [RCV000052959] Chr2:190310736..241892770 [GRCh38]
Chr2:191175462..242834921 [GRCh37]
Chr2:190883707..242483594 [NCBI36]
Chr2:2q32.2-37.3		 pathogenic
GRCh38/hg38 2q32.3-37.3(chr2:193122313-241074980)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052960]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052960]|See cases [RCV000052960] Chr2:193122313..241074980 [GRCh38]
Chr2:193987039..242014395 [GRCh37]
Chr2:193695284..241663068 [NCBI36]
Chr2:2q32.3-37.3		 pathogenic
GRCh38/hg38 2q32.3-33.2(chr2:195660594-203969488)x1 copy number loss See cases [RCV000135341] Chr2:195660594..203969488 [GRCh38]
Chr2:196525318..204834211 [GRCh37]
Chr2:196233563..204542456 [NCBI36]
Chr2:2q32.3-33.2		 pathogenic
GRCh38/hg38 2q32.3-33.1(chr2:195368551-200214331)x1 copy number loss See cases [RCV000135664] Chr2:195368551..200214331 [GRCh38]
Chr2:196233275..201079054 [GRCh37]
Chr2:195941520..200787299 [NCBI36]
Chr2:2q32.3-33.1		 pathogenic
GRCh38/hg38 2q32.1-33.1(chr2:186027472-201059372)x1 copy number loss See cases [RCV000135876] Chr2:186027472..201059372 [GRCh38]
Chr2:186892199..201924095 [GRCh37]
Chr2:186600444..201632340 [NCBI36]
Chr2:2q32.1-33.1		 pathogenic
GRCh38/hg38 2q31.3-36.2(chr2:180513793-224302848)x3 copy number gain See cases [RCV000139446] Chr2:180513793..224302848 [GRCh38]
Chr2:181378520..225167565 [GRCh37]
Chr2:181086765..224875809 [NCBI36]
Chr2:2q31.3-36.2		 pathogenic
GRCh38/hg38 2q32.3-35(chr2:192938826-215705052)x1 copy number loss See cases [RCV000141254] Chr2:192938826..215705052 [GRCh38]
Chr2:193803552..216569775 [GRCh37]
Chr2:193511797..216278020 [NCBI36]
Chr2:2q32.3-35		 pathogenic
GRCh38/hg38 2q32.2-37.3(chr2:189436149-241841232)x3 copy number gain See cases [RCV000142307] Chr2:189436149..241841232 [GRCh38]
Chr2:190300875..242783384 [GRCh37]
Chr2:190009120..242432057 [NCBI36]
Chr2:2q32.2-37.3		 pathogenic
GRCh37/hg19 2q32.3-33.1(chr2:196581377-200947041)x1 copy number loss See cases [RCV000240401] Chr2:196581377..200947041 [GRCh37]
Chr2:2q32.3-33.1		 pathogenic
GRCh37/hg19 2q32.3-33.1(chr2:194581315-201752422)x1 copy number loss See cases [RCV000446984] Chr2:194581315..201752422 [GRCh37]
Chr2:2q32.3-33.1		 pathogenic
GRCh37/hg19 2q31.1-35(chr2:169829974-215521436)x3 copy number gain See cases [RCV000448271] Chr2:169829974..215521436 [GRCh37]
Chr2:2q31.1-35		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
NM_012086.5(GTF3C3):c.2093A>G (p.Asn698Ser) single nucleotide variant not specified [RCV004314972] Chr2:196771915 [GRCh38]
Chr2:197636639 [GRCh37]
Chr2:2q33.1		 uncertain significance
GRCh37/hg19 2q32.3-33.1(chr2:197322697-198094657)x3 copy number gain not provided [RCV000682103] Chr2:197322697..198094657 [GRCh37]
Chr2:2q32.3-33.1		 likely benign
GRCh37/hg19 2q32.3-33.1(chr2:193537927-202027736)x1 copy number loss not provided [RCV000682162] Chr2:193537927..202027736 [GRCh37]
Chr2:2q32.3-33.1		 pathogenic
GRCh37/hg19 2q32.2-33.1(chr2:191750202-202297376)x1 copy number loss not provided [RCV000682165] Chr2:191750202..202297376 [GRCh37]
Chr2:2q32.2-33.1		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q32.2-33.1(chr2:189490490-200615496)x1 copy number loss not provided [RCV000740789] Chr2:189490490..200615496 [GRCh37]
Chr2:2q32.2-33.1		 pathogenic
GRCh37/hg19 2q32.1-34(chr2:185697659-213002074) copy number loss Chromosome 2q32-q33 deletion syndrome [RCV002280608] Chr2:185697659..213002074 [GRCh37]
Chr2:2q32.1-34		 pathogenic
Single allele duplication Neurodevelopmental disorder [RCV000787403] Chr2:188926928..225298653 [GRCh37]
Chr2:2q32.1-36.2		 pathogenic
GRCh37/hg19 2q32.3-33.1(chr2:195786723-200531127)x1 copy number loss not provided [RCV000849862] Chr2:195786723..200531127 [GRCh37]
Chr2:2q32.3-33.1		 pathogenic
GRCh37/hg19 2q24.2-34(chr2:163233162-211927188)x3 copy number gain not provided [RCV001005349] Chr2:163233162..211927188 [GRCh37]
Chr2:2q24.2-34		 pathogenic
NM_012086.5(GTF3C3):c.2180T>C (p.Leu727Pro) single nucleotide variant not specified [RCV004286474] Chr2:196771828 [GRCh38]
Chr2:197636552 [GRCh37]
Chr2:2q33.1		 uncertain significance
GRCh37/hg19 2q32.3-33.1(chr2:197359024-201383462)x1 copy number loss Chromosome 2q32-q33 deletion syndrome [RCV001263250] Chr2:197359024..201383462 [GRCh37]
Chr2:2q32.3-33.1		 pathogenic
GRCh37/hg19 2q32.2-33.1(chr2:190345272-200212289) copy number loss Chromosome 2q32-q33 deletion syndrome [RCV001255693] Chr2:190345272..200212289 [GRCh37]
Chr2:2q32.2-33.1		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q31.2-37.3(chr2:178397959-243007457)x3 copy number gain See cases [RCV001263052] Chr2:178397959..243007457 [GRCh37]
Chr2:2q31.2-37.3		 pathogenic
GRCh37/hg19 2q32.1-33.1(chr2:188294864-197731939)x3 copy number gain not provided [RCV001258567] Chr2:188294864..197731939 [GRCh37]
Chr2:2q32.1-33.1		 likely pathogenic
GRCh37/hg19 2q31.1-35(chr2:169829974-215521436) copy number gain not specified [RCV002053265] Chr2:169829974..215521436 [GRCh37]
Chr2:2q31.1-35		 pathogenic
GRCh37/hg19 2q33.1(chr2:197586481-200793870) copy number loss not specified [RCV002053272] Chr2:197586481..200793870 [GRCh37]
Chr2:2q33.1		 pathogenic
NM_012086.5(GTF3C3):c.1420C>T (p.Arg474Ter) single nucleotide variant Neurodevelopmental disorder [RCV002272964] Chr2:196776600 [GRCh38]
Chr2:197641324 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.2255C>G (p.Ala752Gly) single nucleotide variant not specified [RCV004312049] Chr2:196771753 [GRCh38]
Chr2:197636477 [GRCh37]
Chr2:2q33.1		 uncertain significance
GRCh37/hg19 2q32.2-34(chr2:189909904-209468383)x1 copy number loss not provided [RCV002473800] Chr2:189909904..209468383 [GRCh37]
Chr2:2q32.2-34		 pathogenic
GRCh37/hg19 2q32.1-33.1(chr2:187152754-199960525)x1 copy number loss not provided [RCV002472632] Chr2:187152754..199960525 [GRCh37]
Chr2:2q32.1-33.1		 pathogenic
NM_012086.5(GTF3C3):c.1337C>T (p.Ala446Val) single nucleotide variant not specified [RCV004123316] Chr2:196778949 [GRCh38]
Chr2:197643673 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.827G>A (p.Arg276His) single nucleotide variant not specified [RCV004071503] Chr2:196789270 [GRCh38]
Chr2:197653994 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.2315G>C (p.Cys772Ser) single nucleotide variant not specified [RCV004165382] Chr2:196769985 [GRCh38]
Chr2:197634709 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.587A>G (p.Gln196Arg) single nucleotide variant not specified [RCV004231401] Chr2:196790019 [GRCh38]
Chr2:197654743 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.1190T>C (p.Val397Ala) single nucleotide variant not specified [RCV004236311] Chr2:196780587 [GRCh38]
Chr2:197645311 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.32A>C (p.Tyr11Ser) single nucleotide variant not specified [RCV004121046] Chr2:196799580 [GRCh38]
Chr2:197664304 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.1200C>A (p.Asn400Lys) single nucleotide variant not specified [RCV004105491] Chr2:196780577 [GRCh38]
Chr2:197645301 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.119G>A (p.Gly40Asp) single nucleotide variant not specified [RCV004260202] Chr2:196797892 [GRCh38]
Chr2:197662616 [GRCh37]
Chr2:2q33.1		 uncertain significance
GRCh37/hg19 2q32.1-36.1(chr2:186698504-223918111)x3 copy number gain See cases [RCV003329558] Chr2:186698504..223918111 [GRCh37]
Chr2:2q32.1-36.1		 pathogenic
NM_012086.5(GTF3C3):c.350C>G (p.Thr117Ser) single nucleotide variant not specified [RCV004348823] Chr2:196793017 [GRCh38]
Chr2:197657741 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.353C>T (p.Ala118Val) single nucleotide variant not specified [RCV004342068] Chr2:196793014 [GRCh38]
Chr2:197657738 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.2630A>T (p.Gln877Leu) single nucleotide variant not specified [RCV004350879] Chr2:196764594 [GRCh38]
Chr2:197629318 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.358G>A (p.Asp120Asn) single nucleotide variant not specified [RCV004357502] Chr2:196793009 [GRCh38]
Chr2:197657733 [GRCh37]
Chr2:2q33.1		 uncertain significance
GRCh37/hg19 2q32.3-33.1(chr2:197241559-198122706)x3 copy number gain not provided [RCV003484083] Chr2:197241559..198122706 [GRCh37]
Chr2:2q32.3-33.1		 uncertain significance
GRCh37/hg19 2q32.3-34(chr2:194305623-215261531)x1 copy number loss not specified [RCV003986323] Chr2:194305623..215261531 [GRCh37]
Chr2:2q32.3-34		 pathogenic
NM_012086.5(GTF3C3):c.1920C>G (p.Ser640=) single nucleotide variant GTF3C3-related condition [RCV003958962] Chr2:196773065 [GRCh38]
Chr2:197637789 [GRCh37]
Chr2:2q33.1		 likely benign
NM_012086.5(GTF3C3):c.2524C>G (p.Pro842Ala) single nucleotide variant GTF3C3-related condition [RCV003914230] Chr2:196766579 [GRCh38]
Chr2:197631303 [GRCh37]
Chr2:2q33.1		 likely benign
NM_012086.5(GTF3C3):c.1854C>T (p.Ser618=) single nucleotide variant GTF3C3-related condition [RCV003922311] Chr2:196773131 [GRCh38]
Chr2:197637855 [GRCh37]
Chr2:2q33.1		 likely benign
NM_012086.5(GTF3C3):c.2069+10C>T single nucleotide variant GTF3C3-related condition [RCV003922232] Chr2:196772906 [GRCh38]
Chr2:197637630 [GRCh37]
Chr2:2q33.1		 likely benign
NM_012086.5(GTF3C3):c.338C>G (p.Pro113Arg) single nucleotide variant GTF3C3-related condition [RCV003924322] Chr2:196793029 [GRCh38]
Chr2:197657753 [GRCh37]
Chr2:2q33.1		 benign
NM_012086.5(GTF3C3):c.630G>A (p.Ala210=) single nucleotide variant GTF3C3-related condition [RCV003903851] Chr2:196789976 [GRCh38]
Chr2:197654700 [GRCh37]
Chr2:2q33.1		 likely benign
NM_012086.5(GTF3C3):c.1855G>A (p.Val619Ile) single nucleotide variant not specified [RCV004388529] Chr2:196773130 [GRCh38]
Chr2:197637854 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.1963T>C (p.Tyr655His) single nucleotide variant not specified [RCV004388530] Chr2:196773022 [GRCh38]
Chr2:197637746 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.2644A>G (p.Thr882Ala) single nucleotide variant not specified [RCV004388533] Chr2:196764580 [GRCh38]
Chr2:197629304 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.629C>T (p.Ala210Val) single nucleotide variant not specified [RCV004388534] Chr2:196789977 [GRCh38]
Chr2:197654701 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.980A>T (p.Glu327Val) single nucleotide variant not specified [RCV004388535] Chr2:196785502 [GRCh38]
Chr2:197650226 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.2098C>T (p.Pro700Ser) single nucleotide variant not specified [RCV004388532] Chr2:196771910 [GRCh38]
Chr2:197636634 [GRCh37]
Chr2:2q33.1		 uncertain significance
NM_012086.5(GTF3C3):c.209A>G (p.Asn70Ser) single nucleotide variant GTF3C3-related condition [RCV003974006] Chr2:196797802 [GRCh38]
Chr2:197662526 [GRCh37]
Chr2:2q33.1		 benign
NM_012086.5(GTF3C3):c.309GGA[8] (p.Glu111_Thr112insGlu) microsatellite GTF3C3-related condition [RCV003968968] Chr2:196793037..196793038 [GRCh38]
Chr2:197657761..197657762 [GRCh37]
Chr2:2q33.1		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2139
Count of miRNA genes:914
Interacting mature miRNAs:1089
Transcripts:ENST00000263956, ENST00000409364, ENST00000416690, ENST00000435252, ENST00000448087, ENST00000448539, ENST00000451088, ENST00000455546, ENST00000466862, ENST00000470386, ENST00000481098
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH102800  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372197,627,953 - 197,628,077UniSTSGRCh37
Build 362197,336,198 - 197,336,322RGDNCBI36
Celera2191,383,821 - 191,383,945RGD
Cytogenetic Map2q33.1UniSTS
HuRef2189,480,542 - 189,480,666UniSTS
GeneMap99-GB4 RH Map2617.0UniSTS
GTF3C3_7941  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372197,628,909 - 197,629,396UniSTSGRCh37
Build 362197,337,154 - 197,337,641RGDNCBI36
Celera2191,384,777 - 191,385,264RGD
HuRef2189,481,498 - 189,481,985UniSTS
RH12123  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372197,628,723 - 197,628,887UniSTSGRCh37
Build 362197,336,968 - 197,337,132RGDNCBI36
Celera2191,384,591 - 191,384,755RGD
Cytogenetic Map2q33.1UniSTS
HuRef2189,481,312 - 189,481,476UniSTS
GeneMap99-GB4 RH Map2617.0UniSTS
SHGC-33860  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372197,662,485 - 197,662,593UniSTSGRCh37
Build 362197,370,730 - 197,370,838RGDNCBI36
Celera2191,418,353 - 191,418,461RGD
Cytogenetic Map2q33.1UniSTS
HuRef2189,515,094 - 189,515,202UniSTS
GeneMap99-GB4 RH Map2618.38UniSTS
Whitehead-RH Map2944.7UniSTS
GeneMap99-G3 RH Map28737.0UniSTS
RH70336  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372197,629,017 - 197,629,276UniSTSGRCh37
Build 362197,337,262 - 197,337,521RGDNCBI36
Celera2191,384,885 - 191,385,144RGD
Cytogenetic Map2q33.1UniSTS
HuRef2189,481,606 - 189,481,865UniSTS
GeneMap99-GB4 RH Map2617.11UniSTS
A009K42  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372197,628,796 - 197,628,931UniSTSGRCh37
Build 362197,337,041 - 197,337,176RGDNCBI36
Celera2191,384,664 - 191,384,799RGD
Cytogenetic Map2q33.1UniSTS
HuRef2189,481,385 - 189,481,520UniSTS
GeneMap99-GB4 RH Map2617.11UniSTS
G32628  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372197,628,796 - 197,628,931UniSTSGRCh37
Celera2191,384,664 - 191,384,799UniSTS
Cytogenetic Map2q33.1UniSTS
HuRef2189,481,385 - 189,481,520UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1148 774 985 128 1025 89 3000 605 1160 212 1197 1263 57 1 836 1699 5
Low 1291 2180 741 496 891 376 1357 1590 2574 207 263 350 118 368 1089 1 2
Below cutoff 37 35 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_030373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_012086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005246965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054344614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC012486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF085850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF133123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF465407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH004836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK025560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK027050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK314718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL137453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC036952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF594763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ024746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU622956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB078021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000263956   ⟹   ENSP00000263956
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,763,035 - 196,799,683 (-)Ensembl
RefSeq Acc Id: ENST00000409364   ⟹   ENSP00000386465
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,780,089 - 196,799,659 (-)Ensembl
RefSeq Acc Id: ENST00000416690   ⟹   ENSP00000391724
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,773,007 - 196,776,445 (-)Ensembl
RefSeq Acc Id: ENST00000435252   ⟹   ENSP00000394065
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,774,989 - 196,776,588 (-)Ensembl
RefSeq Acc Id: ENST00000448087   ⟹   ENSP00000398385
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,777,639 - 196,785,536 (-)Ensembl
RefSeq Acc Id: ENST00000448539   ⟹   ENSP00000406685
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,792,955 - 196,799,725 (-)Ensembl
RefSeq Acc Id: ENST00000451088   ⟹   ENSP00000438797
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,792,951 - 196,799,628 (-)Ensembl
RefSeq Acc Id: ENST00000455546   ⟹   ENSP00000389992
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,790,033 - 196,799,515 (-)Ensembl
RefSeq Acc Id: ENST00000466862
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,778,964 - 196,780,901 (-)Ensembl
RefSeq Acc Id: ENST00000470386
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,785,444 - 196,791,897 (-)Ensembl
RefSeq Acc Id: ENST00000481098
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,764,579 - 196,767,004 (-)Ensembl
RefSeq Acc Id: ENST00000651042   ⟹   ENSP00000499170
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2196,763,729 - 196,799,706 (-)Ensembl
RefSeq Acc Id: NM_001206774   ⟹   NP_001193703
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382196,780,082 - 196,799,683 (-)NCBI
GRCh372197,627,756 - 197,664,492 (-)NCBI
HuRef2189,480,345 - 189,517,101 (-)NCBI
CHM1_12197,650,679 - 197,670,344 (-)NCBI
T2T-CHM13v2.02197,263,786 - 197,283,354 (-)NCBI
Sequence:
RefSeq Acc Id: NM_012086   ⟹   NP_036218
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382196,763,035 - 196,799,683 (-)NCBI
GRCh372197,627,756 - 197,664,492 (-)NCBI
Build 362197,337,345 - 197,372,670 (-)NCBI Archive
Celera2191,384,968 - 191,420,293 (-)RGD
HuRef2189,480,345 - 189,517,101 (-)NCBI
CHM1_12197,633,622 - 197,670,344 (-)NCBI
T2T-CHM13v2.02197,246,743 - 197,283,354 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005246965   ⟹   XP_005247022
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382196,763,035 - 196,784,856 (-)NCBI
GRCh372197,627,756 - 197,664,492 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054344614   ⟹   XP_054200589
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.02197,246,743 - 197,268,561 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_036218   ⟸   NM_012086
- Peptide Label: isoform 1
- UniProtKB: Q9H5I8 (UniProtKB/Swiss-Prot),   Q96B44 (UniProtKB/Swiss-Prot),   Q8WX84 (UniProtKB/Swiss-Prot),   Q86XJ8 (UniProtKB/Swiss-Prot),   Q4ZG48 (UniProtKB/Swiss-Prot),   Q9NT97 (UniProtKB/Swiss-Prot),   Q9Y5Q9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001193703   ⟸   NM_001206774
- Peptide Label: isoform 2
- UniProtKB: Q9Y5Q9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005247022   ⟸   XM_005246965
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000438797   ⟸   ENST00000451088
RefSeq Acc Id: ENSP00000499170   ⟸   ENST00000651042
RefSeq Acc Id: ENSP00000389992   ⟸   ENST00000455546
RefSeq Acc Id: ENSP00000391724   ⟸   ENST00000416690
RefSeq Acc Id: ENSP00000398385   ⟸   ENST00000448087
RefSeq Acc Id: ENSP00000406685   ⟸   ENST00000448539
RefSeq Acc Id: ENSP00000386465   ⟸   ENST00000409364
RefSeq Acc Id: ENSP00000263956   ⟸   ENST00000263956
RefSeq Acc Id: ENSP00000394065   ⟸   ENST00000435252
RefSeq Acc Id: XP_054200589   ⟸   XM_054344614
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Y5Q9-F1-model_v2 AlphaFold Q9Y5Q9 1-886 view protein structure

Promoters
RGD ID:6862406
Promoter ID:EPDNEW_H4368
Type:initiation region
Name:GTF3C3_1
Description:general transcription factor IIIC subunit 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382196,799,654 - 196,799,714EPDNEW
RGD ID:6797546
Promoter ID:HG_KWN:36510
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000256104,   OTTHUMT00000335035,   OTTHUMT00000336368,   UC002UTU.2
Position:
Human AssemblyChrPosition (strand)Source
Build 362197,372,331 - 197,372,831 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:4666 AgrOrtholog
COSMIC GTF3C3 COSMIC
Ensembl Genes ENSG00000119041 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000263956 ENTREZGENE
  ENST00000263956.8 UniProtKB/Swiss-Prot
  ENST00000409364 ENTREZGENE
  ENST00000409364.3 UniProtKB/Swiss-Prot
  ENST00000416690.5 UniProtKB/TrEMBL
  ENST00000435252.1 UniProtKB/TrEMBL
  ENST00000448087.5 UniProtKB/TrEMBL
  ENST00000448539.1 UniProtKB/TrEMBL
  ENST00000451088.6 UniProtKB/TrEMBL
  ENST00000651042.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000119041 GTEx
HGNC ID HGNC:4666 ENTREZGENE
Human Proteome Map GTF3C3 Human Proteome Map
InterPro Tfc4/TFIIIC-102/Sfc4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:9330 UniProtKB/Swiss-Prot
NCBI Gene 9330 ENTREZGENE
OMIM 604888 OMIM
PANTHER GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23082 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TPR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA29054 PharmGKB
PROSITE TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot
SMART TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494C1S7_HUMAN UniProtKB/TrEMBL
  F8WC64_HUMAN UniProtKB/TrEMBL
  H0YFI7_HUMAN UniProtKB/TrEMBL
  H7BZV8_HUMAN UniProtKB/TrEMBL
  H7C0C0_HUMAN UniProtKB/TrEMBL
  H7C143_HUMAN UniProtKB/TrEMBL
  Q4ZG48 ENTREZGENE
  Q86XJ8 ENTREZGENE
  Q8WX84 ENTREZGENE
  Q96B44 ENTREZGENE
  Q9H5I8 ENTREZGENE
  Q9NT97 ENTREZGENE
  Q9Y5Q9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q4ZG48 UniProtKB/Swiss-Prot
  Q86XJ8 UniProtKB/Swiss-Prot
  Q8WX84 UniProtKB/Swiss-Prot
  Q96B44 UniProtKB/Swiss-Prot
  Q9H5I8 UniProtKB/Swiss-Prot
  Q9NT97 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-17 GTF3C3  general transcription factor IIIC subunit 3  GTF3C3  general transcription factor IIIC, polypeptide 3, 102kDa  Symbol and/or name change 5135510 APPROVED