Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | multiple interactions | ISO | MGAM (Homo sapiens) | 6480464 | [Estradiol co-treated with Norethindrone Acetate] results in increased expression of MGAM mRNA | CTD | PMID:22217510 | 17beta-estradiol | multiple interactions | ISO | Mgam (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of MGAM mRNA | CTD | PMID:32741896 | 17beta-estradiol 3-benzoate | multiple interactions | ISO | Mgam (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of MGAM mRNA | CTD | PMID:32741896 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MGAM mRNA | CTD | PMID:29704546 | 2-palmitoylglycerol | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of MGAM mRNA | CTD | PMID:37199045 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of MGAM mRNA | CTD | PMID:28973697 | acarbose | decreases activity | ISO | MGAM (Homo sapiens) | 6480464 | Acarbose results in decreased activity of MGAM protein | CTD | PMID:20349118 | acarbose | decreases activity | EXP | | 6480464 | Acarbose results in decreased activity of MGAM protein | CTD | PMID:17585022 | acrylamide | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | Acrylamide results in increased expression of MGAM mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of MGAM mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of MGAM mRNA | CTD | PMID:27153756 | Aflatoxin B2 alpha | increases methylation | ISO | MGAM (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of MGAM intron | CTD | PMID:30157460 | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | [MGAM protein results in increased metabolism of maltodextrin] which results in increased abundance of Glucose and [MGAM protein results in increased metabolism of Maltose] which results in increased abundance of Glucose | CTD | PMID:17585022 | all-trans-retinoic acid | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | Tretinoin results in increased expression of MGAM mRNA | CTD | PMID:33167477 | antirheumatic drug | decreases expression | ISO | MGAM (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of MGAM mRNA | CTD | PMID:24449571 | belinostat | decreases expression | ISO | MGAM (Homo sapiens) | 6480464 | belinostat results in decreased expression of MGAM mRNA | CTD | PMID:27188386 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of MGAM mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases methylation | ISO | MGAM (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of MGAM 5' UTR more ... | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | MGAM (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of MGAM mRNA | CTD | PMID:22178795 | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzo(b)fluoranthene results in increased expression of MGAM mRNA | CTD | PMID:26377693 | benzo[e]pyrene | increases methylation | ISO | MGAM (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of MGAM intron | CTD | PMID:30157460 | beta-maltose | increases metabolic processing | EXP | | 6480464 | MGAM protein results in increased metabolism of Maltose | CTD | PMID:17585022 | beta-maltose | multiple interactions | EXP | | 6480464 | [MGAM protein results in increased metabolism of Maltose] which results in increased abundance of Glucose | CTD | PMID:17585022 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MGAM mRNA | CTD | PMID:26063408 | bisphenol A | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | bisphenol A results in increased expression of MGAM mRNA | CTD | PMID:29275510 | cadmium dichloride | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of MGAM mRNA | CTD | PMID:26314618 | cadmium dichloride | decreases expression | ISO | MGAM (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of MGAM mRNA | CTD | PMID:26472689 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of MGAM mRNA | CTD | PMID:37019170 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of MGAM mRNA | CTD | PMID:20938992 | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of MGAM mRNA | CTD | PMID:28472532 | cisplatin | multiple interactions | ISO | MGAM (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of MGAM mRNA | CTD | PMID:27392435 | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of MGAM mRNA | CTD | PMID:23811191 | cyclosporin A | decreases expression | ISO | MGAM (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of MGAM mRNA | CTD | PMID:27989131 | D-glucose | multiple interactions | EXP | | 6480464 | [MGAM protein results in increased metabolism of maltodextrin] which results in increased abundance of Glucose and [MGAM protein results in increased metabolism of Maltose] which results in increased abundance of Glucose | CTD | PMID:17585022 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of MGAM mRNA | CTD | PMID:21266533 | dioxygen | multiple interactions | ISO | Mgam (Rattus norvegicus) | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of MGAM mRNA | CTD | PMID:33729688 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of MGAM mRNA | CTD | PMID:20938992 | glucose | multiple interactions | EXP | | 6480464 | [MGAM protein results in increased metabolism of maltodextrin] which results in increased abundance of Glucose and [MGAM protein results in increased metabolism of Maltose] which results in increased abundance of Glucose | CTD | PMID:17585022 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of MGAM mRNA | CTD | PMID:20938992 | linear maltodextrin | multiple interactions | EXP | | 6480464 | [MGAM protein results in increased metabolism of maltodextrin] which results in increased abundance of Glucose | CTD | PMID:17585022 | linear maltodextrin | increases metabolic processing | EXP | | 6480464 | MGAM protein results in increased metabolism of maltodextrin | CTD | PMID:17585022 | lipopolysaccharide | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of MGAM mRNA | CTD | PMID:35811015 | lipopolysaccharide | multiple interactions | ISO | MGAM (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of MGAM mRNA | CTD | PMID:35811015 | maltose | increases metabolic processing | EXP | | 6480464 | MGAM protein results in increased metabolism of Maltose | CTD | PMID:17585022 | maltose | multiple interactions | EXP | | 6480464 | [MGAM protein results in increased metabolism of Maltose] which results in increased abundance of Glucose | CTD | PMID:17585022 | methapyrilene | increases methylation | ISO | MGAM (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of MGAM intron | CTD | PMID:30157460 | methylisothiazolinone | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of MGAM mRNA | CTD | PMID:31629900 | ozone | multiple interactions | ISO | MGAM (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of MGAM mRNA | CTD | PMID:26035830 | permethrin | decreases expression | ISO | MGAM (Homo sapiens) | 6480464 | Permethrin results in decreased expression of MGAM mRNA | CTD | PMID:37047231 | pioglitazone | multiple interactions | EXP | | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MGAM mRNA | CTD | PMID:27935865 | potassium dichromate | increases expression | EXP | | 6480464 | Potassium Dichromate results in increased expression of MGAM mRNA | CTD | PMID:23608068 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of MGAM mRNA | CTD | PMID:28903501 | rotenone | decreases expression | ISO | Mgam (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of MGAM mRNA | CTD | PMID:28374803 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | MGAM (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of MGAM mRNA | CTD | PMID:35811015 | silicon dioxide | decreases expression | ISO | MGAM (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of MGAM mRNA | CTD | PMID:25895662 | sodium arsenite | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of MGAM mRNA | CTD | PMID:29301061 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of MGAM mRNA | CTD | PMID:37682722 | starch | increases metabolic processing | EXP | | 6480464 | MGAM protein results in increased metabolism of Starch | CTD | PMID:17585022 | sulforaphane | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | sulforaphane results in increased expression of MGAM mRNA | CTD | PMID:26833863 | testosterone | multiple interactions | ISO | Mgam (Rattus norvegicus) | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of MGAM mRNA | CTD | PMID:32741896 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of MGAM mRNA | CTD | PMID:27339419 and PMID:31919559 | Theaflavin 3,3'-digallate | affects expression | ISO | MGAM (Homo sapiens) | 6480464 | theaflavin-3 and 3'-digallate affects the expression of MGAM mRNA | CTD | PMID:34925699 | thioacetamide | decreases expression | ISO | Mgam (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of MGAM mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of MGAM mRNA | CTD | PMID:23557971 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of MGAM mRNA | CTD | PMID:33045310 | urethane | increases expression | ISO | MGAM (Homo sapiens) | 6480464 | Urethane results in increased expression of MGAM mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | MGAM (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of MGAM mRNA | CTD | PMID:29154799 | vancomycin | increases expression | EXP | | 6480464 | Vancomycin results in increased expression of MGAM mRNA | CTD | PMID:18930951 | vinclozolin | increases methylation | ISO | Mgam (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of MGAM gene | CTD | PMID:31682807 | XL147 | multiple interactions | EXP | | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of MGAM mRNA | CTD | PMID:27935865 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Molecular Pathway Annotations Click to see Annotation Detail View
Imported Annotations - SMPDB
Imported Annotations - KEGG (archival)
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Function
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Molecular Pathway Annotations
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Phenotype Annotations
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Mammalian Phenotype
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 2. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 3. | SMPDB Annotation Import Pipeline | Pipeline to import SMPDB annotations from SMPDB into RGD |
| 4. | Mouse MP Annotation Import Pipeline | RGD automated import pipeline |
| 5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:9446624 | PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:11217851 | PMID:12122147 | PMID:12150962 | PMID:12466851 | PMID:12477932 | PMID:14681479 | PMID:16141072 | PMID:16141073 |
| PMID:17585022 | PMID:19193815 | PMID:20425755 | PMID:21267068 | PMID:21873635 | PMID:25857663 | PMID:28245920 |
Genomics
Comparative Map Data
| Mgam (Mus musculus - house mouse) |
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| MGAM (Homo sapiens - human) |
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| Mgam (Rattus norvegicus - Norway rat) |
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| MGAM (Pan paniscus - bonobo/pygmy chimpanzee) |
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| MGAM (Canis lupus familiaris - dog) |
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| Mgam (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| MGAM (Sus scrofa - pig) |
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| MGAM (Chlorocebus sabaeus - green monkey) |
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| Mgam (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Mgam
4070 total Variants 
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