Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of RELL1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RELL1 mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | increases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in increased expression of RELL1 mRNA | CTD | PMID:25380136 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of RELL1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RELL1 mRNA | CTD | PMID:33387578 and PMID:34747641 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | tetrabromobisphenol A results in increased expression of RELL1 mRNA | CTD | PMID:27914987 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RELL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of RELL1 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of RELL1 mRNA | CTD | PMID:25380136 and PMID:30723492 | 4,4'-sulfonyldiphenol | increases expression | EXP | | 6480464 | bisphenol S results in increased expression of RELL1 mRNA | CTD | PMID:33297965 | 6-propyl-2-thiouracil | decreases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of RELL1 mRNA | CTD | PMID:24780913 and PMID:25825206 | acetamide | increases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | acetamide results in increased expression of RELL1 mRNA | CTD | PMID:31881176 | aflatoxin B1 | increases methylation | ISO | RELL1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of RELL1 gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | RELL1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of RELL1 mRNA | CTD | PMID:33167477 | antirheumatic drug | decreases expression | ISO | RELL1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of RELL1 mRNA | CTD | PMID:24449571 | benzo[a]pyrene | increases methylation | ISO | RELL1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of RELL1 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | RELL1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of RELL1 mRNA | CTD | PMID:32234424 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RELL1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzo(b)fluoranthene results in increased expression of RELL1 mRNA | CTD | PMID:26377693 | bisphenol A | decreases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of RELL1 mRNA | CTD | PMID:25181051 and PMID:34947998 | bisphenol A | multiple interactions | ISO | RELL1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of RELL1 gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of RELL1 mRNA | CTD | PMID:28628672 and PMID:31601247 | caffeine | affects phosphorylation | ISO | RELL1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of RELL1 protein | CTD | PMID:35688186 | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of RELL1 mRNA | CTD | PMID:23811191 | cobalt dichloride | decreases expression | ISO | RELL1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of RELL1 mRNA | CTD | PMID:19320972 | crocidolite asbestos | decreases methylation | ISO | RELL1 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in decreased methylation of RELL1 3' UTR | CTD | PMID:29523930 | Cuprizon | decreases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of RELL1 mRNA | CTD | PMID:26577399 | cyclosporin A | increases expression | ISO | RELL1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of RELL1 mRNA | CTD | PMID:20106945 | dexamethasone | multiple interactions | ISO | RELL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of RELL1 mRNA | CTD | PMID:28628672 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of RELL1 mRNA | CTD | PMID:21266533 | dorsomorphin | multiple interactions | ISO | RELL1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | RELL1 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of RELL1 mRNA | CTD | PMID:29803840 | ethyl methanesulfonate | increases expression | ISO | RELL1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of RELL1 mRNA | CTD | PMID:23649840 | fipronil | increases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | fipronil results in increased expression of RELL1 mRNA | CTD | PMID:31881178 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RELL1 mRNA | CTD | PMID:22206623 | formaldehyde | increases expression | ISO | RELL1 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of RELL1 mRNA | CTD | PMID:23649840 | FR900359 | affects phosphorylation | ISO | RELL1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of RELL1 protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | RELL1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of RELL1 gene | CTD | PMID:31601247 | furan | increases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | furan results in increased expression of RELL1 mRNA | CTD | PMID:25539665 | indole-3-methanol | affects expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | indole-3-carbinol affects the expression of RELL1 mRNA | CTD | PMID:21396975 | indometacin | multiple interactions | ISO | RELL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of RELL1 mRNA | CTD | PMID:28628672 | methapyrilene | decreases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of RELL1 mRNA | CTD | PMID:30467583 | methyl methanesulfonate | increases expression | ISO | RELL1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of RELL1 mRNA | CTD | PMID:23649840 | N-nitrosodimethylamine | increases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | Dimethylnitrosamine results in increased expression of RELL1 mRNA | CTD | PMID:25380136 | orphenadrine | affects expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | Orphenadrine affects the expression of RELL1 mRNA | CTD | PMID:23665939 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of RELL1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | RELL1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of RELL1 mRNA | CTD | PMID:21420995 | phenobarbital | multiple interactions | EXP | | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of RELL1 mRNA] | CTD | PMID:19482888 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of RELL1 mRNA | CTD | PMID:23091169 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of RELL1 mRNA | CTD | PMID:19270015 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of RELL1 mRNA | CTD | PMID:19482888 | pirinixic acid | multiple interactions | EXP | | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of RELL1 mRNA | CTD | PMID:19710929 | propiconazole | decreases expression | EXP | | 6480464 | propiconazole results in decreased expression of RELL1 mRNA | CTD | PMID:21278054 | SB 431542 | multiple interactions | ISO | RELL1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenate | decreases expression | EXP | | 6480464 | sodium arsenate results in decreased expression of RELL1 mRNA | CTD | PMID:30953684 | sodium arsenite | increases expression | ISO | RELL1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of RELL1 mRNA | CTD | PMID:28595984 | sodium arsenite | affects expression | ISO | RELL1 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of RELL1 mRNA | CTD | PMID:29319823 | Soman | increases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | Soman results in increased expression of RELL1 mRNA | CTD | PMID:19281266 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of RELL1 mRNA | CTD | PMID:31919559 | thimerosal | decreases expression | EXP | | 6480464 | Thimerosal results in decreased expression of RELL1 mRNA | CTD | PMID:24675092 | trichostatin A | increases expression | ISO | RELL1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of RELL1 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | affects expression | ISO | RELL1 (Homo sapiens) | 6480464 | trichostatin A affects the expression of RELL1 mRNA | CTD | PMID:28542535 | trichostatin A | multiple interactions | ISO | RELL1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RELL1 mRNA | CTD | PMID:27188386 | triphenyl phosphate | increases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | triphenyl phosphate results in increased expression of RELL1 mRNA | CTD | PMID:30589522 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of RELL1 mRNA | CTD | PMID:28973697 | trovafloxacin | decreases expression | EXP | | 6480464 | trovafloxacin results in decreased expression of RELL1 mRNA | CTD | PMID:35537566 | valdecoxib | increases expression | ISO | Rell1 (Rattus norvegicus) | 6480464 | valdecoxib results in increased expression of RELL1 mRNA | CTD | PMID:24136188 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of RELL1 mRNA | CTD | PMID:19136453 | valproic acid | affects expression | ISO | RELL1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RELL1 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | RELL1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RELL1 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | RELL1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of RELL1 mRNA | CTD | PMID:23179753 more ... | vinclozolin | decreases methylation | ISO | Rell1 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased methylation of RELL1 gene | CTD | PMID:31682807 | |