Kin (Kin17 DNA and RNA binding protein)

Gene: Kin (Kin17 DNA and RNA binding protein) Mus musculus

Analyze

Symbol:

Kin

Name:

Kin17 DNA and RNA binding protein

RGD ID:

1315718

MGI Page

MGI

Description:

Enables double-stranded DNA binding activity. Involved in DNA damage response and DNA replication. Located in nucleus. Is expressed in several structures, including branchial arch; inner ear; limb; liver; and midgut. Orthologous to human KIN (Kin17 DNA and RNA binding protein).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

binding to curved DNA; DNA/RNA-binding protein KIN17; KIN, antigenic determinant of recA protein homolog; Kin17

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KIN (Kin17 DNA and RNA binding protein)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Kin (Kin17 DNA and RNA binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Kin (Kin17 DNA and RNA binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KIN (Kin17 DNA and RNA binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KIN (Kin17 DNA and RNA binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Kin (Kin17 DNA and RNA binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KIN (Kin17 DNA and RNA binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KIN (Kin17 DNA and RNA binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Kin (Kin17 DNA and RNA binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	KIN (Kin17 DNA and RNA binding protein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Kin (Kin17 DNA and RNA binding protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	kin (Kin17 DNA and RNA binding protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	dxbp-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RTS2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	kin17	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Related Pseudogenes:

Gm20945 Gm9586

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	10,085,397 - 10,097,512 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	10,085,404 - 10,097,617 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	10,080,551 - 10,092,701 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	10,080,593 - 10,092,806 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	10,002,239 - 10,014,328 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	9,998,465 - 10,010,554 (+)	NCBI		MGSCv36	mm8
Celera	2	10,019,685 - 10,031,776 (+)	NCBI		Celera
Cytogenetic Map	2	A1	NCBI
cM Map	2	6.88	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

hypoparathyroidism-deafness-renal disease syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-hydroxypropanoic acid (ISO)

2-palmitoylglycerol (ISO)

6-propyl-2-thiouracil (ISO)

aconitine (ISO)

amitrole (ISO)

benzo[a]pyrene (EXP)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

caffeine (ISO)

clofibrate (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dicrotophos (ISO)

folic acid (EXP)

formaldehyde (ISO)

furan (ISO)

gold atom (ISO)

gold(0) (ISO)

hydrogen peroxide (ISO)

inulin (EXP)

methimazole (ISO)

paracetamol (EXP)

PCB138 (EXP)

perfluorooctane-1-sulfonic acid (EXP)

rac-lactic acid (ISO)

sodium arsenite (EXP)

sulfadimethoxine (ISO)

theophylline (ISO)

trichostatin A (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA damage response (IBA,IEP)

DNA recombination (IEA)

DNA repair (IEA)

DNA replication (IBA,IDA,ISO)

mRNA processing (IEA)

Cellular Component

cytoplasm (IEA)

intracellular membrane-bounded organelle (ISO)

nuclear matrix (ISO)

nucleoplasm (ISO)

nucleus (IBA,IDA)

protein-containing complex (ISO)

Molecular Function

DNA binding (IEA)

double-stranded DNA binding (IBA,IDA)

metal ion binding (IEA)

protein binding (ISO)

RNA binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased circulating calcium level (IEA)

embryonic lethality prior to organogenesis (IEA)

increased heart rate (IEA)

preweaning lethality, complete penetrance (IEA)

shortened RR interval (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:795416	PMID:1378530	PMID:1447303	PMID:1715759	PMID:1923796	PMID:2493134	PMID:7937163	PMID:8078469	PMID:8824764	PMID:8954809	PMID:10349636	PMID:10964102
PMID:11042159	PMID:11076861	PMID:11544199	PMID:12477932	PMID:15252136	PMID:16141072	PMID:16141073	PMID:20059953	PMID:21267068	PMID:21510876	PMID:21677750	PMID:21873635
PMID:21909369	PMID:27853268	PMID:34321999

Genomics

Comparative Map Data

Kin
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	10,085,397 - 10,097,512 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	10,085,404 - 10,097,617 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	10,080,551 - 10,092,701 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	10,080,593 - 10,092,806 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	10,002,239 - 10,014,328 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	9,998,465 - 10,010,554 (+)	NCBI		MGSCv36	mm8
Celera	2	10,019,685 - 10,031,776 (+)	NCBI		Celera
Cytogenetic Map	2	A1	NCBI
cM Map	2	6.88	NCBI

KIN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	7,750,962 - 7,787,993 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	7,750,962 - 7,787,993 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	7,792,925 - 7,829,956 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	7,837,373 - 7,869,950 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	7,837,372 - 7,869,950	NCBI
Celera	10	7,723,177 - 7,755,764 (-)	NCBI		Celera
Cytogenetic Map	10	p14	NCBI
HuRef	10	7,711,272 - 7,748,358 (-)	NCBI		HuRef
CHM1_1	10	7,792,885 - 7,829,730 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	7,751,725 - 7,788,763 (-)	NCBI		T2T-CHM13v2.0

Kin
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	73,323,189 - 73,333,542 (-)	NCBI		GRCr8
mRatBN7.2	17	68,413,483 - 68,431,392 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	68,413,486 - 68,423,845 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	71,895,970 - 71,906,291 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	75,724,704 - 75,735,025 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	69,767,757 - 69,778,078 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	72,198,882 - 72,216,780 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	72,198,866 - 72,209,279 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	73,884,586 - 73,902,539 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	79,728,511 - 79,738,856 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	17	67,899,986 - 67,910,331 (-)	NCBI		Celera
Cytogenetic Map	17	q12.3	NCBI

Kin
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955421	24,196,909 - 24,234,320 (-)	NCBI	ChiLan1.0	ChiLan1.0

KIN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	20,299,905 - 20,339,559 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	20,307,073 - 20,344,886 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	7,783,842 - 7,820,778 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	7,764,233 - 7,801,350 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	7,768,263 - 7,801,350 (-)	Ensembl	panpan1.1		panPan2

KIN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	28,325,243 - 28,360,790 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	28,324,723 - 28,360,773 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	25,366,091 - 25,401,647 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	28,706,828 - 28,742,388 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	28,706,316 - 28,742,371 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	25,813,254 - 25,848,818 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	26,655,185 - 26,690,736 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	27,373,305 - 27,408,834 (+)	NCBI		UU_Cfam_GSD_1.0

Kin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	30,865,976 - 30,893,520 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936484	7,030,862 - 7,060,125 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936484	7,031,160 - 7,058,696 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KIN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	63,599,632 - 63,631,001 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	63,599,612 - 63,634,844 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

KIN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	7,801,716 - 7,836,958 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	7,799,492 - 7,836,719 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666051	13,197,734 - 13,232,609 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kin
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624775	2,716,150 - 2,745,442 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624775	2,715,748 - 2,745,524 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Kin
454 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	277
Count of miRNA genes:	214
Interacting mature miRNAs:	243
Transcripts:	ENSMUST00000042512, ENSMUST00000142599, ENSMUST00000142773
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10045633	Heal15_m	wound healing/regeneration 15 (mouse)			Not determined		2	1	21989642	Mouse
4141836	Tgq11_m	triglyceride QTL 11 (mouse)			Not determined			1	25324559	Mouse
4142333	Tgq10_m	triglyceride QTL 10 (mouse)			Not determined			1	25324559	Mouse
1301838	Sluc16_m	susceptibility to lung cancer 16 (mouse)			Not determined		2	1	26529589	Mouse
12904743	Carcdq3_m	cardiac collagen deposition QTL 3 (mouse)					2	3234940	28179150	Mouse
1301769	Orgwq2_m	organ weight QTL 2 (mouse)			Not determined		2	3887126	93421651	Mouse
1301980	Fcsa5_m	femoral cross-sectional area 5 (mouse)			Not determined		2	7679115	41679261	Mouse
1301790	Pcfm1_m	periosteal circumference and femur length 1 (mouse)			Not determined		2	8236296	42236396	Mouse
10043876	Adip22_m	adiposity 22 (mouse)			Not determined		2	8308051	42308240	Mouse
1300624	Insq7_m	insulin QTL 7 (mouse)			Not determined		2	9384446	43384575	Mouse
10755513	Amzn4_m	anatomical modifier of Zfp423 4 (mouse)					2	9384446	43384575	Mouse
12903993	Opfaq1_m	open field activity QTL 1 (mouse)					2	9676691	27022642	Mouse

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001420343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001420344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_025280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_185163	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AK009429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK132548	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK167740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL772367	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC028860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC058169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X58472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92450	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000042512 ⟹ ENSMUSP00000043614

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	10,085,435 - 10,097,617 (+)	Ensembl
GRCm38.p6 Ensembl	2	10,080,624 - 10,092,806 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000142599

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	10,085,404 - 10,096,630 (+)	Ensembl
GRCm38.p6 Ensembl	2	10,080,593 - 10,091,819 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000142773

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	10,095,108 - 10,096,990 (+)	Ensembl
GRCm38.p6 Ensembl	2	10,090,297 - 10,092,179 (+)	Ensembl

RefSeq Acc Id:

NM_001420343 ⟹ NP_001407272

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	2	10,085,397 - 10,097,512 (+)	NCBI

RefSeq Acc Id:

NM_001420344 ⟹ NP_001407273

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	2	10,085,397 - 10,097,512 (+)	NCBI

RefSeq Acc Id:

NM_025280 ⟹ NP_079556

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	2	10,085,397 - 10,097,512 (+)	NCBI
GRCm38	2	10,080,612 - 10,092,701 (+)	NCBI
MGSCv37	2	10,002,239 - 10,014,328 (+)	RGD
Celera	2	10,019,685 - 10,031,776 (+)	RGD
cM Map	2		ENTREZGENE

Sequence:

show sequence

TGTAGCGCTCAGGGTCGCCATGGGCAAGTCGGATTTTCTGAGCCCCAAGGCCATCGCCAATAGA
ATTAAGTCCAAAGGGCTCCAGAAGCTTCGCTGGTACTGCCAGATGTGCCAAAAGCAATGCCGCG
ACGAGAATGGCTTTAAGTGTCACTGTATGTCTGAATCTCATCAAAGACAACTGTTGCTGGCTTC
AGAAAACCCTCAGCAGTTTATGGATTATTTTTCAGAGGAATTCCGAAATGACTTTCTGGAACTT
CTGAGGCGACGCTTTGGCACTAAAAGGGTCCACAACAACATTGTCTACAATGAATACATCAGCC
ACCGAGAGCACATCCACATGAACGCTACCCAGTGGGAGACACTGACCGACTTTACCAAGTGGCT
GGGCAGAGAGGGCTTGTGTAAAGTGGATGAGACACCGAAAGGCTGGTACATTCAGTACATAGAC
AGAGACCCAGAAACCATCCGTCGGCAACTGGAATTAGAAAAAAAGAAGAAGCAAGATCTGGACG
ATGAAGAAAAAACTGCCAAGTTCATTGAGGAGCAGGTGAGAAGAGGCCTGGAAGGGAAAGAGCA
GGAGACACCTGTTTTTACAGAACTTAGCCGAGAAAATGAGGAAGAAAAAGTTACGTTCAATCTG
AATAAAGGAGCGGGTGGCTCAGCGGGAGCTACAACATCCAAGTCAAGCTCTTTGGGACCAAGTG
CACTGAAGCTGCTGGGGAGCGCAGCATCCGGGAAACGGAAAGAGTCTTCACAGAGCTCCGCCCA
GCCTGCGAAGAAGAAGAAGTCGGCCCTGGATGAGATCATGGAGCTCGAAGAGGAAAAGAAAAGG
ACCGCACGGACAGACGCCTGGTTACAGCCGGGGATCGTTGTGAAAATTATAACGAAGAAGCTTG
GGGAGAAATATCACAAGAAGAAAGGGGTCGTTAAGGAAGTGATTGACAGGTACACAGCTGTGGT
AAAGATGACTGACTCTGGAGACAGGCTGAAACTGGACCAGACTCATTTAGAGACAGTCATTCCG
GCCCCGGGGAAAAGGGTTCTAGTTTTAAATGGAGGCTACAGAGGAAATGAAGGCACTCTCGAAT
CCATCAATGAGAAGGCTTTTTCAGCCACGATAGTCATTGAAACTGGACCTTTGAAAGGACGCAG
AGTTGAAGGTATTCAATATGAAGACATATCTAAACTTGCTTGAGTTTGAAAATTTGATAACAAC
ACATTGAAACTGTGAAGCATCAAATTGGTGTTAGCCAAGGCACTGTGTAACTCTACTGTGTTAG
GGGATTTGTTTTGTATTAAAAAAAAAAAAATCATCTATTTAAATACTAGTGAATAGTTGGGTAA
ATTTATAATAAAATCTATGTTTTTTTTAAGTGTCA

hide sequence

RefSeq Acc Id:

NR_185163

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	2	10,085,397 - 10,097,512 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001407272	(Get FASTA)	NCBI Sequence Viewer
	NP_001407273	(Get FASTA)	NCBI Sequence Viewer
	NP_079556	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH28860	(Get FASTA)	NCBI Sequence Viewer
	BAB26281	(Get FASTA)	NCBI Sequence Viewer
	BAE39778	(Get FASTA)	NCBI Sequence Viewer
	EDL08002	(Get FASTA)	NCBI Sequence Viewer
	EDL08003	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000043614
	ENSMUSP00000043614.8
GenBank Protein	Q8K339	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_079556 ⟸ NM_025280
- Peptide Label:	isoform 1
- UniProtKB:	Q9CV58 (UniProtKB/Swiss-Prot), Q8K339 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQF MDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLC KVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVRRGLEGKEQETPVFT ELSRENEEEKVTFNLNKGAGGSAGATTSKSSSLGPSALKLLGSAASGKRKESSQSSAQPAKKKK SALDEIMELEEEKKRTARTDAWLQPGIVVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMTDSG DRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKAFSATIVIETGPLKGRRVEGIQY EDISKLA hide sequence

RefSeq Acc Id:

ENSMUSP00000043614 ⟸ ENSMUST00000042512

RefSeq Acc Id:	NP_001407273 ⟸ NM_001420344
- Peptide Label:	isoform 3

RefSeq Acc Id:	NP_001407272 ⟸ NM_001420343
- Peptide Label:	isoform 2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8K339-F1-model_v2	AlphaFold	Q8K339	1-391	view protein structure

Promoters

RGD ID:

6830846

Promoter ID:

MM_KWN:27679

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

ENSMUST00000026887, ENSMUST00000114896, OTTMUST00000026255, OTTMUST00000026256, OTTMUST00000026264, OTTMUST00000026265, OTTMUST00000042198, OTTMUST00000042199, OTTMUST00000042200, UC008IHO.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	2	10,001,851 - 10,002,351 (-)	MPROMDB

RGD ID:

6831671

Promoter ID:

MM_KWN:27680

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Liver

Transcripts:

OTTMUST00000026266

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	2	10,011,566 - 10,012,066 (+)	MPROMDB

RGD ID:

6876316

Promoter ID:

EPDNEW_M1609

Type:

initiation region

Name:

Kin_1

Description:

Mus musculus Kin17 DNA and RNA binding protein , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	2	10,080,586 - 10,080,646	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:96676	AgrOrtholog
Ensembl Genes	ENSMUSG00000037262	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000042512	ENTREZGENE
	ENSMUST00000042512.8	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.10.2030	UniProtKB/Swiss-Prot
	2.30.30.140	UniProtKB/Swiss-Prot
	2.30.30.30	UniProtKB/Swiss-Prot
InterPro	DNA/RNA-bd_Kin17_cons_domain	UniProtKB/Swiss-Prot
	KIN17-like	UniProtKB/Swiss-Prot
	KIN17_WH-like_sf	UniProtKB/Swiss-Prot
	KN17_SH3	UniProtKB/Swiss-Prot
	KOW_KIN17	UniProtKB/Swiss-Prot
	Rib_L2_dom2	UniProtKB/Swiss-Prot
	Znf_C2H2_sf	UniProtKB/Swiss-Prot
KEGG Report	mmu:16588	UniProtKB/Swiss-Prot
MGD	MGI:96676	ENTREZGENE
NCBI Gene	16588	ENTREZGENE
PANTHER	DNA/RNA-BINDING PROTEIN KIN17	UniProtKB/Swiss-Prot
	PTHR12805	UniProtKB/Swiss-Prot
Pfam	Kin17_mid	UniProtKB/Swiss-Prot
	KN17_SH3	UniProtKB/Swiss-Prot
PhenoGen	Kin	PhenoGen
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/Swiss-Prot
SMART	Kin17_mid	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF57667	UniProtKB/Swiss-Prot
UniProt	KIN17_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q9CV58	ENTREZGENE
UniProt Secondary	Q9CV58	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-02	Kin	Kin17 DNA and RNA binding protein		antigenic determinant of rec-A protein	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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