Txk (TXK tyrosine kinase) - Rat Genome Database

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Gene: Txk (TXK tyrosine kinase) Mus musculus
Analyze
Symbol: Txk
Name: TXK tyrosine kinase
RGD ID: 1315123
MGI Page MGI
Description: Predicted to enable non-membrane spanning protein tyrosine kinase activity. Involved in T cell receptor signaling pathway; adaptive immune response; and positive regulation of cytokine production. Acts upstream of or within NK T cell differentiation. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including hemolymphoid system; lung; male reproductive gland or organ; stomach mesentery; and vertebral axis musculature. Orthologous to human TXK (TXK tyrosine kinase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A130089B16Rik; Btk; Btkl; PTK; PTK-RL-18; PTK4; R; resting lymphocyte kinase; Rlk; tyrosine-protein kinase TXK
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39572,853,321 - 72,910,337 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl572,853,321 - 72,910,120 (-)EnsemblGRCm39 Ensembl
GRCm38572,695,978 - 72,752,992 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl572,695,978 - 72,752,777 (-)EnsemblGRCm38mm10GRCm38
MGSCv37573,087,217 - 73,144,012 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36572,975,117 - 73,015,737 (-)NCBIMGSCv36mm8
Celera569,944,742 - 70,002,864 (-)NCBICelera
Cytogenetic Map5C3.2NCBI
cM Map538.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)
membrane  (IEA)
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)
plasma membrane  (IBA,ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. MGD IEA MGD IEA
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7542761   PMID:7579892   PMID:7829530   PMID:8632917   PMID:10213685   PMID:10343129   PMID:10349636   PMID:10562318   PMID:10843805   PMID:11015440   PMID:11042159   PMID:11076861  
PMID:11114734   PMID:11217851   PMID:11702066   PMID:12477932   PMID:12798690   PMID:15662016   PMID:16141072   PMID:16141073   PMID:16237085   PMID:16424186   PMID:16602821   PMID:16860759  
PMID:16860760   PMID:17698926   PMID:18025201   PMID:18292523   PMID:18941202   PMID:19449311   PMID:19818650   PMID:20639398   PMID:20974963   PMID:21036902   PMID:21267068   PMID:21677750  
PMID:21873635   PMID:22403441   PMID:24194600   PMID:26466958   PMID:31757864   PMID:32325033   PMID:34036382   PMID:38355793  


Genomics

Comparative Map Data
Txk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39572,853,321 - 72,910,337 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl572,853,321 - 72,910,120 (-)EnsemblGRCm39 Ensembl
GRCm38572,695,978 - 72,752,992 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl572,695,978 - 72,752,777 (-)EnsemblGRCm38mm10GRCm38
MGSCv37573,087,217 - 73,144,012 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36572,975,117 - 73,015,737 (-)NCBIMGSCv36mm8
Celera569,944,742 - 70,002,864 (-)NCBICelera
Cytogenetic Map5C3.2NCBI
cM Map538.44NCBI
TXK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38448,066,393 - 48,134,250 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl448,066,393 - 48,134,250 (-)EnsemblGRCh38hg38GRCh38
GRCh37448,068,410 - 48,136,267 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36447,763,167 - 47,831,030 (-)NCBINCBI36Build 36hg18NCBI36
Build 34447,909,688 - 47,977,201NCBI
Celera448,517,268 - 48,584,988 (-)NCBICelera
Cytogenetic Map4p12NCBI
HuRef447,388,494 - 47,456,038 (-)NCBIHuRef
CHM1_1448,067,554 - 48,135,380 (-)NCBICHM1_1
T2T-CHM13v2.0448,033,459 - 48,101,082 (-)NCBIT2T-CHM13v2.0
Txk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81435,817,270 - 35,873,454 (+)NCBIGRCr8
mRatBN7.21435,463,369 - 35,519,448 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1435,463,944 - 35,519,448 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1435,828,243 - 35,884,548 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01437,132,987 - 37,189,292 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01435,621,349 - 35,677,656 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01438,029,809 - 38,085,822 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1438,030,189 - 38,085,919 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01437,840,106 - 37,896,117 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41437,867,565 - 37,923,075 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11437,870,891 - 37,926,425 (+)NCBI
Celera1434,718,226 - 34,773,309 (+)NCBICelera
Cytogenetic Map14p11NCBI
Txk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955443474,099 - 556,697 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955443474,099 - 556,697 (+)NCBIChiLan1.0ChiLan1.0
TXK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2379,730,977 - 79,801,494 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1479,992,362 - 80,063,009 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0474,039,292 - 74,086,744 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1484,750,804 - 84,818,671 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl484,750,804 - 84,818,671 (+)Ensemblpanpan1.1panPan2
TXK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11343,911,881 - 43,977,499 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1343,914,534 - 43,976,655 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1343,865,388 - 43,929,029 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01344,512,768 - 44,576,339 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1344,514,039 - 44,576,331 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11344,190,147 - 44,253,820 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01343,722,001 - 43,785,908 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01344,605,279 - 44,668,806 (-)NCBIUU_Cfam_GSD_1.0
Txk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528532,066,522 - 32,108,331 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648214,190,409 - 14,245,943 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648214,190,409 - 14,231,690 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TXK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl837,977,986 - 38,046,933 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1837,977,222 - 38,047,876 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2840,028,569 - 40,096,747 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TXK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1272,120,429 - 2,186,950 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl272,140,685 - 2,190,398 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604748,133,664 - 48,203,278 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Txk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476118,841,795 - 18,897,458 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476118,841,795 - 18,897,564 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Txk
2206 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:361
Count of miRNA genes:167
Interacting mature miRNAs:196
Transcripts:ENSMUST00000113604, ENSMUST00000169534
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
1301698Pcfm4_mperiosteal circumference and femur length 4 (mouse)Not determined54458584378585965Mouse
13207584Mwmlpt4_mMorris water maze latency to platform, training, 4 (mouse)54632260680322606Mouse
13207588Mwmlpa4_mMorris water maze latency to platform, all, 4 (mouse)54632260680322606Mouse
14746981Manh57_mmandible shape 57 (mouse)54716974281169742Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
1301243Bmd2_mbone mineral density 2 (mouse)Not determined555388334100455525Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55388334108762627Mouse
13464248Ahl13_mage related hearing loss, early onset 13 (mouse)55564587489645995Mouse
10043962Obq27_mobesity QTL 27 (mouse)Not determined55628565590285655Mouse
10044005Ahl7_mage related hearing loss 7 (mouse)Not determined55833050292330641Mouse
11040591Lmr3c_mleishmaniasis resistance 3c (mouse)55960280193602980Mouse
11040592Lmr3d_mleishmaniasis resistance 3d (mouse)55960280193602980Mouse
11040589Lmr3a_mleishmaniasis resistance 3a (mouse)55960280193602980Mouse
11040590Lmr3b_mleishmaniasis resistance 3b (mouse)55960280193602980Mouse
1301843Listr1_mlisteriosis resistance 1 (mouse)Not determined56024608194246203Mouse
13464247Ahl14_mage related hearing loss, early onset 14 (mouse)56040306294403160Mouse
11252124Modvl6_mmodifier of vacuolated lens 6 (mouse)56265056896650688Mouse
4142428Modvl1_mmodifier of vacuolated lens 1 (mouse)Not determined6265056896650688Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56265056896650688Mouse
13464250Ahl15_mage related hearing loss, early onset 15 (mouse)56265056896650688Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563705442104387065Mouse
11049560Lmr24d_mleishmaniasis resistance 24d (mouse)56437487798374996Mouse
12904739M2fscn2_mmodifier 2 of FSCN2 (mouse)566529661100529661Mouse
12904740M1fscn2_mmodifier 1 of Fscn2 (mouse)566529661100529661Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
10043993Hbnr10_mHeligmosomoides bakeri nematode resistance 10 (mouse)Not determined572418876106419011Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse

Markers in Region
D43963  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5C3.2UniSTS
Whitehead_YAC5 UniSTS
Txk  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,696,285 - 72,696,582UniSTSGRCm38
MGSCv37573,087,524 - 73,087,821UniSTSGRCm37
Celera569,945,049 - 69,945,346UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map540.0UniSTS
D5Nds2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,750,852 - 72,751,015UniSTSGRCm38
MGSCv37573,142,091 - 73,142,254UniSTSGRCm37
Celera570,000,943 - 70,001,106UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map541.0UniSTS
Txk  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38572,696,271 - 72,696,483UniSTSGRCm38
MGSCv37573,087,510 - 73,087,722UniSTSGRCm37
Celera569,945,035 - 69,945,247UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map540.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001122754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011240722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH007959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB236068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC120552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC137710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D43963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D83201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D83202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U16145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U19607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000113604   ⟹   ENSMUSP00000109234
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl572,853,321 - 72,910,120 (-)Ensembl
GRCm38.p6 Ensembl572,695,978 - 72,752,777 (-)Ensembl
RefSeq Acc Id: ENSMUST00000169534   ⟹   ENSMUSP00000129397
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl572,853,321 - 72,893,945 (-)Ensembl
GRCm38.p6 Ensembl572,695,978 - 72,736,602 (-)Ensembl
RefSeq Acc Id: ENSMUST00000197313   ⟹   ENSMUSP00000143476
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl572,853,321 - 72,910,116 (-)Ensembl
GRCm38.p6 Ensembl572,695,978 - 72,752,773 (-)Ensembl
RefSeq Acc Id: ENSMUST00000197843
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl572,860,813 - 72,910,117 (-)Ensembl
GRCm38.p6 Ensembl572,703,470 - 72,752,774 (-)Ensembl
RefSeq Acc Id: ENSMUST00000197923
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl572,905,904 - 72,910,113 (-)Ensembl
GRCm38.p6 Ensembl572,748,561 - 72,752,770 (-)Ensembl
RefSeq Acc Id: ENSMUST00000198464   ⟹   ENSMUSP00000143002
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl572,853,323 - 72,910,116 (-)Ensembl
GRCm38.p6 Ensembl572,695,980 - 72,752,773 (-)Ensembl
RefSeq Acc Id: ENSMUST00000198798
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl572,853,329 - 72,893,249 (-)Ensembl
GRCm38.p6 Ensembl572,695,986 - 72,735,906 (-)Ensembl
RefSeq Acc Id: ENSMUST00000198970
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl572,853,329 - 72,893,249 (-)Ensembl
GRCm38.p6 Ensembl572,695,986 - 72,735,906 (-)Ensembl
RefSeq Acc Id: NM_001122754   ⟹   NP_001116226
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39572,853,321 - 72,910,120 (-)NCBI
GRCm38572,695,978 - 72,752,777 (-)NCBI
MGSCv37573,087,217 - 73,144,012 (-)RGD
Celera569,944,742 - 70,002,868 (-)NCBI
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001289494   ⟹   NP_001276423
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39572,853,321 - 72,910,120 (-)NCBI
GRCm38572,695,978 - 72,752,777 (-)NCBI
Celera569,944,742 - 70,002,868 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001289495   ⟹   NP_001276424
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39572,853,321 - 72,910,120 (-)NCBI
GRCm38572,695,978 - 72,752,777 (-)NCBI
Celera569,944,742 - 70,002,868 (-)NCBI
Sequence:
RefSeq Acc Id: NM_013698   ⟹   NP_038726
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39572,853,321 - 72,893,945 (-)NCBI
GRCm38572,695,978 - 72,736,602 (-)NCBI
MGSCv37573,087,217 - 73,144,012 (-)RGD
Celera569,944,742 - 70,002,868 (-)NCBI
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011240722   ⟹   XP_011239024
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39572,853,324 - 72,910,335 (-)NCBI
GRCm38572,695,981 - 72,752,992 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164998   ⟹   XP_036020891
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39572,855,058 - 72,910,337 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_038726   ⟸   NM_013698
- Peptide Label: isoform 2
- UniProtKB: B2RQ20 (UniProtKB/TrEMBL),   Q0VBP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001116226   ⟸   NM_001122754
- Peptide Label: isoform 1
- UniProtKB: P42682 (UniProtKB/Swiss-Prot),   Q0VBP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276423   ⟸   NM_001289494
- Peptide Label: isoform 3
- UniProtKB: A0A0G2JG94 (UniProtKB/TrEMBL),   Q0VBP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001276424   ⟸   NM_001289495
- Peptide Label: isoform 4
- UniProtKB: Q0VBP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011239024   ⟸   XM_011240722
- Peptide Label: isoform X2
- UniProtKB: Q0VBP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000143002   ⟸   ENSMUST00000198464
RefSeq Acc Id: ENSMUSP00000143476   ⟸   ENSMUST00000197313
RefSeq Acc Id: ENSMUSP00000109234   ⟸   ENSMUST00000113604
RefSeq Acc Id: ENSMUSP00000129397   ⟸   ENSMUST00000169534
RefSeq Acc Id: XP_036020891   ⟸   XM_036164998
- Peptide Label: isoform X1
- UniProtKB: Q0VBP6 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase   SH2   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P42682-F1-model_v2 AlphaFold P42682 1-527 view protein structure

Promoters
RGD ID:6886860
Promoter ID:EPDNEW_M6881
Type:initiation region
Name:Txk_2
Description:Mus musculus TXK tyrosine kinase , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6882  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38572,736,605 - 72,736,665EPDNEW
RGD ID:6886862
Promoter ID:EPDNEW_M6882
Type:initiation region
Name:Txk_1
Description:Mus musculus TXK tyrosine kinase , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6881  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38572,752,773 - 72,752,833EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102960 AgrOrtholog
Ensembl Genes ENSMUSG00000054892 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000113604 ENTREZGENE
  ENSMUST00000113604.10 UniProtKB/Swiss-Prot
  ENSMUST00000169534 ENTREZGENE
  ENSMUST00000169534.6 UniProtKB/TrEMBL
  ENSMUST00000197313 ENTREZGENE
  ENSMUST00000197313.5 UniProtKB/TrEMBL
  ENSMUST00000198464 ENTREZGENE
  ENSMUST00000198464.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.505.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Txk_SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TXK_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22165 UniProtKB/Swiss-Prot
MGD MGI:102960 ENTREZGENE
NCBI Gene 22165 ENTREZGENE
PANTHER TYROSINE-PROTEIN KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE TXK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB TXK RGD
PhenoGen Txk PhenoGen
PRINTS SH2DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYRKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JG94 ENTREZGENE, UniProtKB/TrEMBL
  B2RQ20 ENTREZGENE, UniProtKB/TrEMBL
  P42682 ENTREZGENE
  Q0VBP6 ENTREZGENE, UniProtKB/TrEMBL
  TXK_MOUSE UniProtKB/Swiss-Prot