Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of FAM171A1 mRNA | CTD | PMID:28960355 | 17beta-estradiol | multiple interactions | ISO | FAM171A1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of FAM171A1 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FAM171A1 mRNA | CTD | PMID:21570461 and PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FAM171A1 mRNA | CTD | PMID:20106945 more ... | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | FAM171A1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of FAM171A1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | FAM171A1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of FAM171A1 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of FAM171A1 mRNA | CTD | PMID:28973697 | 5-fluorouracil | affects response to substance | ISO | FAM171A1 (Homo sapiens) | 6480464 | FAM171A1 protein affects the susceptibility to Fluorouracil | CTD | PMID:16217747 | 6-propyl-2-thiouracil | increases expression | ISO | Fam171a1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of FAM171A1 mRNA | CTD | PMID:24780913 | aflatoxin B1 | decreases methylation | ISO | FAM171A1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of FAM171A1 intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of FAM171A1 mRNA | CTD | PMID:16788091 | antirheumatic drug | increases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of FAM171A1 mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of FAM171A1 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | FAM171A1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of FAM171A1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | FAM171A1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of FAM171A1 gene | CTD | PMID:25304211 | arsenite(3-) | increases methylation | ISO | FAM171A1 (Homo sapiens) | 6480464 | arsenite results in increased methylation of FAM171A1 promoter | CTD | PMID:23974009 | atrazine | affects methylation | ISO | Fam171a1 (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of FAM171A1 gene | CTD | PMID:35440735 | benzo[a]pyrene | increases mutagenesis | ISO | FAM171A1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of FAM171A1 gene | CTD | PMID:25435355 | benzo[a]pyrene | affects methylation | ISO | FAM171A1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FAM171A1 intron | CTD | PMID:30157460 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of FAM171A1 mRNA | CTD | PMID:22228805 and PMID:32417428 | benzo[a]pyrene | increases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of FAM171A1 mRNA | CTD | PMID:22316170 | benzo[e]pyrene | decreases methylation | ISO | FAM171A1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of FAM171A1 intron | CTD | PMID:30157460 | bisphenol A | affects expression | ISO | Fam171a1 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of FAM171A1 mRNA | CTD | PMID:25181051 | caffeine | affects phosphorylation | ISO | FAM171A1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of FAM171A1 protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of FAM171A1 mRNA | CTD | PMID:28472532 | cisplatin | decreases expression | ISO | Fam171a1 (Rattus norvegicus) | 6480464 | Cisplatin results in decreased expression of FAM171A1 mRNA | CTD | PMID:22023808 | cisplatin | multiple interactions | ISO | FAM171A1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of FAM171A1 mRNA | CTD | PMID:27392435 | cisplatin | decreases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of FAM171A1 mRNA | CTD | PMID:19561079 | cobalt dichloride | decreases expression | ISO | Fam171a1 (Rattus norvegicus) | 6480464 | cobaltous chloride results in decreased expression of FAM171A1 mRNA | CTD | PMID:24386269 | crocidolite asbestos | decreases expression | EXP | | 6480464 | Asbestos and Crocidolite results in decreased expression of FAM171A1 mRNA | CTD | PMID:29279043 | cyclosporin A | decreases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of FAM171A1 mRNA | CTD | PMID:25562108 | dexamethasone | multiple interactions | ISO | FAM171A1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of FAM171A1 mRNA | CTD | PMID:28628672 | doxorubicin | affects response to substance | ISO | FAM171A1 (Homo sapiens) | 6480464 | FAM171A1 protein affects the susceptibility to Doxorubicin | CTD | PMID:16217747 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of FAM171A1 mRNA | CTD | PMID:35436446 | ethanol | affects expression | EXP | | 6480464 | Ethanol affects the expression of FAM171A1 mRNA | CTD | PMID:30319688 | etoposide | affects response to substance | ISO | FAM171A1 (Homo sapiens) | 6480464 | FAM171A1 protein affects the susceptibility to Etoposide | CTD | PMID:16217747 | fenvalerate | increases expression | ISO | Fam171a1 (Rattus norvegicus) | 6480464 | fenvalerate results in increased expression of FAM171A1 mRNA | CTD | PMID:30307764 | fipronil | increases expression | ISO | Fam171a1 (Rattus norvegicus) | 6480464 | fipronil results in increased expression of FAM171A1 mRNA | CTD | PMID:23962444 | FR900359 | increases phosphorylation | ISO | FAM171A1 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of FAM171A1 protein | CTD | PMID:37730182 | glyphosate | decreases methylation | ISO | Fam171a1 (Rattus norvegicus) | 6480464 | Glyphosate results in decreased methylation of FAM171A1 gene | CTD | PMID:31011160 | indometacin | multiple interactions | ISO | FAM171A1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of FAM171A1 mRNA | CTD | PMID:28628672 | leflunomide | increases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | leflunomide results in increased expression of FAM171A1 mRNA | CTD | PMID:28988120 | methapyrilene | decreases methylation | ISO | FAM171A1 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of FAM171A1 intron | CTD | PMID:30157460 | methotrexate | affects response to substance | ISO | FAM171A1 (Homo sapiens) | 6480464 | FAM171A1 protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 | methoxychlor | affects methylation | ISO | Fam171a1 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of FAM171A1 gene | CTD | PMID:35440735 | milrinone | decreases expression | ISO | Fam171a1 (Rattus norvegicus) | 6480464 | Milrinone results in decreased expression of FAM171A1 mRNA | CTD | PMID:22936366 | mitomycin C | affects response to substance | ISO | FAM171A1 (Homo sapiens) | 6480464 | FAM171A1 protein affects the susceptibility to Mitomycin | CTD | PMID:16217747 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of FAM171A1 mRNA | CTD | PMID:24535843 | paracetamol | decreases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of FAM171A1 mRNA | CTD | PMID:21420995 | phenobarbital | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of FAM171A1 mRNA and NR1I3 protein affects the reaction [Phenobarbital results in increased expression of FAM171A1 mRNA] | CTD | PMID:19482888 and PMID:24535843 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of FAM171A1 mRNA | CTD | PMID:23091169 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of FAM171A1 mRNA | CTD | PMID:19270015 and PMID:19482888 | pirinixic acid | multiple interactions | EXP | | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of FAM171A1 mRNA | CTD | PMID:19710929 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of FAM171A1 mRNA | CTD | PMID:23811191 | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of FAM171A1 mRNA | CTD | PMID:21278054 | quercetin | increases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Quercetin results in increased expression of FAM171A1 mRNA | CTD | PMID:21632981 | sodium dodecyl sulfate | increases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Sodium Dodecyl Sulfate results in increased expression of FAM171A1 mRNA | CTD | PMID:31734321 | temozolomide | decreases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of FAM171A1 mRNA | CTD | PMID:31758290 | tert-butyl hydroperoxide | decreases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of FAM171A1 mRNA | CTD | PMID:29432895 | thioacetamide | increases expression | ISO | Fam171a1 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of FAM171A1 mRNA | CTD | PMID:34492290 | topotecan | affects response to substance | ISO | FAM171A1 (Homo sapiens) | 6480464 | FAM171A1 protein affects the susceptibility to Topotecan | CTD | PMID:16217747 | trimellitic anhydride | decreases expression | EXP | | 6480464 | trimellitic anhydride results in decreased expression of FAM171A1 mRNA | CTD | PMID:19042947 | urethane | decreases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of FAM171A1 mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | ISO | FAM171A1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of FAM171A1 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of FAM171A1 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | FAM171A1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of FAM171A1 mRNA | CTD | PMID:28001369 and PMID:29154799 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 |
Welcome {{ username}}
Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{gene.symbol}}: {{ gene.description }}
|
| You must be logged in to use this feature |
| {{ loginError }} |
|
|
Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
 |
Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
|
MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
|
||||||||||
Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Gene-Chemical Interaction Annotations
Click to see Annotation Detail View
Gene Ontology Annotations
Click to see Annotation Detail View
Phenotype Annotations
Click to see Annotation Detail View
References
References - curated
| # | Reference Title | Reference Citation |
| 1. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 2. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:11125038 | PMID:11217851 | PMID:12466851 | PMID:12477932 | PMID:15782199 | PMID:16141072 | PMID:16141073 | PMID:21267068 | PMID:21677750 |
| PMID:21873635 | PMID:28671696 |
Genomics
Comparative Map Data
| Fam171a1 (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| FAM171A1 (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Fam171a1 (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Fam171a1 (Chinchilla lanigera - long-tailed chinchilla) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| FAM171A1 (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| FAM171A1 (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Fam171a1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| FAM171A1 (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| FAM171A1 (Chlorocebus sabaeus - green monkey) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Fam171a1 (Heterocephalus glaber - naked mole-rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Variants
.
Variants in Fam171a1
3005 total Variants 
|
