Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of UBE2G2 mRNA] | CTD | PMID:31150632 | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of UBE2G2 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of UBE2G2 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBE2G2 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of UBE2G2 mRNA | CTD | PMID:17942748 | 17beta-estradiol | increases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Estradiol results in increased expression of UBE2G2 mRNA | CTD | PMID:31614463 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBE2G2 mRNA and [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of UBE2G2 mRNA | CTD | PMID:17942748 and PMID:25975270 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of UBE2G2 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of UBE2G2 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of UBE2G2 mRNA | CTD | PMID:22903824 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of UBE2G2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of UBE2G2 mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of UBE2G2 mRNA] | CTD | PMID:21215274 | 2,4-dinitrotoluene | affects expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of UBE2G2 mRNA | CTD | PMID:21346803 | 2,6-di-tert-butyl-4-methylphenol | increases expression | EXP | | 6480464 | Butylated Hydroxytoluene results in increased expression of UBE2G2 mRNA | CTD | PMID:19925653 | acrylamide | increases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of UBE2G2 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of UBE2G2 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of UBE2G2 mRNA | CTD | PMID:33167477 | antirheumatic drug | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of UBE2G2 mRNA | CTD | PMID:24449571 | arsane | multiple interactions | ISO | UBE2G2 (Homo sapiens) | 6480464 | [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to UBE2G2 promoter] and [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of UBE2G2 protein | CTD | PMID:35625704 | arsenic atom | multiple interactions | ISO | UBE2G2 (Homo sapiens) | 6480464 | [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to UBE2G2 promoter] and [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of UBE2G2 protein | CTD | PMID:35625704 | arsenic trichloride | multiple interactions | ISO | UBE2G2 (Homo sapiens) | 6480464 | [arsenic trichloride results in increased abundance of Arsenic] promotes the reaction [NFE2L2 protein binds to UBE2G2 promoter] and [arsenic trichloride results in increased abundance of Arsenic] which results in increased expression of UBE2G2 protein | CTD | PMID:35625704 | atrazine | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of UBE2G2 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of UBE2G2 mRNA | CTD | PMID:21569818 | benzo[a]pyrene | decreases methylation | ISO | UBE2G2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of UBE2G2 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of UBE2G2 mRNA | CTD | PMID:22228805 | bisphenol A | increases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of UBE2G2 mRNA | CTD | PMID:25181051 more ... | bisphenol A | multiple interactions | ISO | UBE2G2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of UBE2G2 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of UBE2G2 mRNA | CTD | PMID:32145629 | bisphenol A | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of UBE2G2 mRNA | CTD | PMID:29275510 | Bisphenol B | increases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of UBE2G2 protein | CTD | PMID:34186270 | cadmium dichloride | decreases methylation | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased methylation of UBE2G2 promoter | CTD | PMID:22457795 | cadmium dichloride | increases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of UBE2G2 mRNA | CTD | PMID:26472689 | cadmium dichloride | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of UBE2G2 mRNA | CTD | PMID:25596134 | cadmium dichloride | increases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased expression of UBE2G2 mRNA | CTD | PMID:33453195 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon results in increased expression of UBE2G2 mRNA | CTD | PMID:25554681 and PMID:25620056 | CGP 52608 | multiple interactions | ISO | UBE2G2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to UBE2G2 gene] | CTD | PMID:28238834 | cidofovir anhydrous | increases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Cidofovir results in increased expression of UBE2G2 mRNA | CTD | PMID:25596134 | cisplatin | increases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of UBE2G2 mRNA | CTD | PMID:25596134 | clobetasol | increases expression | EXP | | 6480464 | Clobetasol results in increased expression of UBE2G2 mRNA | CTD | PMID:27462272 | clodronic acid | increases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Clodronic Acid results in increased expression of UBE2G2 mRNA | CTD | PMID:25596134 | cobalt dichloride | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of UBE2G2 mRNA | CTD | PMID:19320972 | crocidolite asbestos | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in decreased expression of UBE2G2 mRNA | CTD | PMID:29523930 | cyclosporin A | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of UBE2G2 mRNA | CTD | PMID:25596134 | Di-n-octyl phthalate | decreases expression | EXP | | 6480464 | di-n-octyl phthalate results in decreased expression of UBE2G2 mRNA | CTD | PMID:37810885 | dicrotophos | increases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of UBE2G2 mRNA | CTD | PMID:28302478 | dimethylarsinic acid | decreases expression | EXP | | 6480464 | Cacodylic Acid results in decreased expression of UBE2G2 mRNA | CTD | PMID:22246474 | dioxygen | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of UBE2G2 mRNA | CTD | PMID:25596134 | endosulfan | increases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of UBE2G2 mRNA | CTD | PMID:29391264 and PMID:31464424 | ethyl methanesulfonate | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of UBE2G2 mRNA | CTD | PMID:23649840 | fenofibrate | affects expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Fenofibrate affects the expression of UBE2G2 mRNA | CTD | PMID:25596134 | flutamide | increases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of UBE2G2 mRNA | CTD | PMID:24136188 | fulvestrant | multiple interactions | ISO | UBE2G2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of UBE2G2 gene | CTD | PMID:31601247 | gentamycin | increases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of UBE2G2 mRNA | CTD | PMID:33387578 | glafenine | increases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Glafenine results in increased expression of UBE2G2 mRNA | CTD | PMID:24136188 | gold atom | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Gold analog results in decreased expression of UBE2G2 mRNA | CTD | PMID:36057382 | gold(0) | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Gold analog results in decreased expression of UBE2G2 mRNA | CTD | PMID:36057382 | ifosfamide | increases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Ifosfamide results in increased expression of UBE2G2 mRNA | CTD | PMID:25596134 | L-serine | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Serine results in decreased expression of UBE2G2 mRNA | CTD | PMID:29098664 | metformin | decreases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Metformin results in decreased expression of UBE2G2 mRNA | CTD | PMID:25596134 | methyl methanesulfonate | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of UBE2G2 mRNA | CTD | PMID:23649840 | N-methyl-4-phenylpyridinium | affects expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium affects the expression of UBE2G2 mRNA | CTD | PMID:25234470 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of UBE2G2 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of UBE2G2 mRNA | CTD | PMID:33387578 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of UBE2G2 mRNA | CTD | PMID:18445702 | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of UBE2G2 mRNA | CTD | PMID:22610192 | tetrachloromethane | increases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of UBE2G2 mRNA | CTD | PMID:31150632 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of UBE2G2 mRNA | CTD | PMID:31919559 | tetrachloromethane | multiple interactions | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of UBE2G2 mRNA] | CTD | PMID:31150632 | thioacetamide | increases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of UBE2G2 mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of UBE2G2 mRNA | CTD | PMID:29128614 and PMID:29264374 | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of UBE2G2 mRNA | CTD | PMID:28973697 | trovafloxacin | increases expression | EXP | | 6480464 | trovafloxacin results in increased expression of UBE2G2 mRNA | CTD | PMID:35537566 | urethane | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Urethane results in decreased expression of UBE2G2 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of UBE2G2 mRNA | CTD | PMID:17292431 | valproic acid | increases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of UBE2G2 mRNA | CTD | PMID:23179753 and PMID:27188386 | valproic acid | decreases methylation | ISO | UBE2G2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of UBE2G2 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of UBE2G2 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of UBE2G2 mRNA | CTD | PMID:23527032 | vinclozolin | decreases expression | ISO | Ube2g2 (Rattus norvegicus) | 6480464 | vinclozolin results in decreased expression of UBE2G2 mRNA | CTD | PMID:18042343 | zinc sulfate | decreases expression | ISO | UBE2G2 (Homo sapiens) | 6480464 | Zinc Sulfate results in decreased expression of UBE2G2 mRNA | CTD | PMID:12756304 | |