Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | affects expression | ISO | FGD3 (Homo sapiens) | 6480464 | Ethinyl Estradiol affects the expression of FGD3 mRNA | CTD | PMID:20170705 | 17beta-estradiol | multiple interactions | ISO | FGD3 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of FGD3 mRNA | CTD | PMID:30165855 | 17beta-estradiol | decreases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of FGD3 mRNA | CTD | PMID:31614463 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | FGD3 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fgd3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FGD3 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FGD3 mRNA | CTD | PMID:34747641 | 2,4,6-tribromophenol | decreases expression | ISO | FGD3 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | FGD3 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of FGD3 protein | CTD | PMID:31675489 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Fgd3 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of FGD3 mRNA | CTD | PMID:28973697 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of FGD3 mRNA | CTD | PMID:31881176 | aflatoxin B1 | increases methylation | ISO | FGD3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of FGD3 intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of FGD3 mRNA | CTD | PMID:33167477 | alpha-Zearalanol | increases expression | EXP | | 6480464 | Zeranol results in increased expression of FGD3 mRNA | CTD | PMID:35163327 | antirheumatic drug | decreases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of FGD3 mRNA | CTD | PMID:24449571 | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of FGD3 mRNA | CTD | PMID:36841081 | benzo[a]pyrene | decreases methylation | ISO | FGD3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of FGD3 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | FGD3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FGD3 intron | CTD | PMID:30157460 | bisphenol A | affects expression | ISO | FGD3 (Homo sapiens) | 6480464 | bisphenol A affects the expression of FGD3 mRNA | CTD | PMID:20170705 | bisphenol A | decreases expression | ISO | FGD3 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of FGD3 protein | CTD | PMID:31675489 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FGD3 mRNA | CTD | PMID:30816183 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of FGD3 mRNA | CTD | PMID:25181051 | buta-1,3-diene | decreases expression | ISO | Fgd3 (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of FGD3 mRNA | CTD | PMID:29038090 | butanal | increases expression | ISO | FGD3 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of FGD3 mRNA | CTD | PMID:26079696 | cadmium atom | multiple interactions | ISO | Fgd3 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of FGD3 mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | ISO | Fgd3 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of FGD3 mRNA | CTD | PMID:37325564 | caffeine | decreases phosphorylation | ISO | FGD3 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of FGD3 protein | CTD | PMID:35688186 | calcitriol | increases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of FGD3 mRNA | CTD | PMID:16002434 | cannabidiol | decreases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Cannabidiol results in decreased expression of FGD3 mRNA | CTD | PMID:33244087 | carbon nanotube | increases expression | ISO | Fgd3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chlorpyrifos | decreases methylation | EXP | | 6480464 | Chlorpyrifos results in decreased methylation of FGD3 gene | CTD | PMID:32905263 | chlorpyrifos | decreases expression | ISO | Fgd3 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of FGD3 mRNA | CTD | PMID:37019170 | choline | multiple interactions | ISO | Fgd3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FGD3 mRNA | CTD | PMID:20938992 | cisplatin | increases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of FGD3 mRNA | CTD | PMID:27594783 | cyclosporin A | increases methylation | ISO | FGD3 (Homo sapiens) | 6480464 | Cyclosporine results in increased methylation of FGD3 promoter | CTD | PMID:27989131 | DDT | increases methylation | EXP | | 6480464 | DDT results in increased methylation of FGD3 gene | CTD | PMID:30207508 | decabromodiphenyl ether | decreases expression | ISO | FGD3 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of FGD3 protein | CTD | PMID:31675489 | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of FGD3 mRNA | CTD | PMID:33729688 | dorsomorphin | multiple interactions | ISO | FGD3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FGD3 mRNA | CTD | PMID:27188386 | ethanol | increases expression | ISO | Fgd3 (Mus musculus) | 6480464 | Ethanol results in increased expression of FGD3 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of FGD3 mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | ISO | Fgd3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FGD3 mRNA | CTD | PMID:20938992 | formaldehyde | increases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of FGD3 mRNA | CTD | PMID:23649840 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of FGD3 mRNA | CTD | PMID:33387578 | hydrogen peroxide | affects expression | ISO | FGD3 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of FGD3 mRNA | CTD | PMID:20044591 | iron dichloride | decreases expression | ISO | FGD3 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of FGD3 mRNA | CTD | PMID:35984750 | L-methionine | multiple interactions | ISO | Fgd3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FGD3 mRNA | CTD | PMID:20938992 | lipopolysaccharide | decreases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of FGD3 mRNA | CTD | PMID:35811015 | lipopolysaccharide | multiple interactions | ISO | FGD3 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of FGD3 gene | CTD | PMID:35440735 | nickel atom | increases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Nickel results in increased expression of FGD3 mRNA | CTD | PMID:24768652 and PMID:25583101 | ozone | multiple interactions | ISO | FGD3 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of FGD3 mRNA | CTD | PMID:35430440 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FGD3 mRNA | CTD | PMID:33387578 | pentanal | increases expression | ISO | FGD3 (Homo sapiens) | 6480464 | pentanal results in increased expression of FGD3 mRNA | CTD | PMID:26079696 | perfluorohexanesulfonic acid | decreases expression | ISO | Fgd3 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of FGD3 mRNA | CTD | PMID:37995155 | propanal | increases expression | ISO | FGD3 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of FGD3 mRNA | CTD | PMID:26079696 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | FGD3 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | FGD3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FGD3 mRNA | CTD | PMID:27188386 | silver atom | increases expression | ISO | Fgd3 (Mus musculus) | 6480464 | Silver results in increased expression of FGD3 mRNA | CTD | PMID:27131904 | silver(0) | increases expression | ISO | Fgd3 (Mus musculus) | 6480464 | Silver results in increased expression of FGD3 mRNA | CTD | PMID:27131904 | succimer | multiple interactions | ISO | Fgd3 (Mus musculus) | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of FGD3 mRNA | CTD | PMID:26378955 | temozolomide | decreases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of FGD3 mRNA | CTD | PMID:31758290 | thalidomide | increases expression | ISO | Fgd3 (Mus musculus) | 6480464 | Thalidomide results in increased expression of FGD3 mRNA | CTD | PMID:26217789 | tungsten | decreases expression | ISO | Fgd3 (Mus musculus) | 6480464 | Tungsten results in decreased expression of FGD3 mRNA | CTD | PMID:30912803 | valproic acid | increases expression | ISO | FGD3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of FGD3 mRNA | CTD | PMID:26272509 | valproic acid | multiple interactions | ISO | FGD3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FGD3 mRNA | CTD | PMID:27188386 | |