Ckap2 (cytoskeleton associated protein 2)

Gene: Ckap2 (cytoskeleton associated protein 2) Rattus norvegicus

Analyze

Symbol:

Ckap2

Name:

cytoskeleton associated protein 2

RGD ID:

1311631

Description:

Predicted to be involved in negative regulation of microtubule depolymerization. Predicted to act upstream of or within mitotic cytokinesis and positive regulation of transcription by RNA polymerase II. Predicted to be located in centrosome and mitotic spindle. Predicted to be active in microtubule cytoskeleton. Orthologous to human CKAP2 (cytoskeleton associated protein 2); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cytoskeleton-associated protein 2; LOC306575

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Related Pseudogenes:

Ckap2-ps3

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	76,542,114 - 76,567,297 (+)	NCBI		GRCr8
mRatBN7.2	16	69,839,668 - 69,864,852 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	69,839,630 - 69,864,913 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	75,113,349 - 75,138,530 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	78,552,184 - 78,576,964 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	73,801,472 - 73,826,252 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	74,752,655 - 74,779,184 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	74,752,655 - 74,779,184 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	74,383,677 - 74,410,206 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	74,492,221 - 74,518,743 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	74,492,485 - 74,519,006 (+)	NCBI
Celera	16	67,729,052 - 67,749,485 (+)	NCBI		Celera
Cytogenetic Map	16	q12.5	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 13q14 deletion syndrome (ISO)

genetic disease (ISO)

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-diaminotoluene (ISO)

2-amino-2-deoxy-D-glucopyranose (EXP)

2-methylcholine (ISO)

2-palmitoylglycerol (ISO)

3-methylcholanthrene (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

7,12-dimethyltetraphene (ISO)

acetamide (EXP)

acrylamide (EXP)

aflatoxin B1 (EXP,ISO)

Aflatoxin B2 alpha (ISO)

aldehydo-D-glucosamine (EXP)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[b]fluoranthene (ISO)

benzo[e]pyrene (ISO)

beta-D-glucosamine (EXP)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

cadmium dichloride (EXP)

caffeine (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

cefaloridine (EXP)

choline (ISO)

chrysene (ISO)

cisplatin (ISO)

clofibrate (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

coumestrol (ISO)

CU-O LINKAGE (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

D-glucose (ISO)

deoxynivalenol (ISO)

diallyl trisulfide (ISO)

diarsenic trioxide (ISO)

dibenz[a,h]anthracene (ISO)

dibutyl phthalate (ISO)

dichloroacetic acid (ISO)

dicrotophos (ISO)

dioxygen (ISO)

diquat (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

Echimidine (EXP)

elemental selenium (ISO)

endosulfan (EXP)

enzyme inhibitor (ISO)

ethyl methanesulfonate (ISO)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

fructose (ISO)

furan (EXP)

gentamycin (EXP)

glucose (ISO)

glycidol (EXP)

glyphosate (ISO)

Heliotrine (EXP)

hydrogen peroxide (ISO)

L-methionine (ISO)

leflunomide (ISO)

lidocaine (EXP)

metformin (ISO)

methamphetamine (EXP)

methapyrilene (EXP,ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

mitomycin C (ISO)

N-nitrosodiethylamine (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (ISO)

PCB138 (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenformin (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

PhIP (EXP)

pirinixic acid (ISO)

progesterone (ISO)

resveratrol (ISO)

rotenone (EXP)

SB 431542 (ISO)

selenium atom (ISO)

senecionine (EXP)

Senkirkine (EXP)

serpentine asbestos (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

sodium fluoride (ISO)

sunitinib (ISO)

tacrolimus hydrate (ISO)

testosterone (EXP,ISO)

testosterone enanthate (ISO)

tetrachloromethane (ISO)

tetraphene (ISO)

thioacetamide (EXP)

titanium dioxide (EXP)

topotecan (EXP,ISO)

trimellitic anhydride (ISO)

Triptolide (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

vincaleukoblastine (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mitotic cytokinesis (ISO)

negative regulation of microtubule depolymerization (IBA,ISO)

positive regulation of transcription by RNA polymerase II (ISO)

Cellular Component

centrosome (ISO)

cytoplasm (IEA)

microtubule cytoskeleton (IBA,ISO)

mitotic spindle (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:16061649	PMID:21399614

Genomics

Comparative Map Data

Ckap2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	76,542,114 - 76,567,297 (+)	NCBI		GRCr8
mRatBN7.2	16	69,839,668 - 69,864,852 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	69,839,630 - 69,864,913 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	75,113,349 - 75,138,530 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	78,552,184 - 78,576,964 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	73,801,472 - 73,826,252 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	74,752,655 - 74,779,184 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	74,752,655 - 74,779,184 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	74,383,677 - 74,410,206 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	74,492,221 - 74,518,743 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	74,492,485 - 74,519,006 (+)	NCBI
Celera	16	67,729,052 - 67,749,485 (+)	NCBI		Celera
Cytogenetic Map	16	q12.5	NCBI

CKAP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	52,455,478 - 52,476,627 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	52,455,429 - 52,476,628 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	53,029,613 - 53,050,762 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	51,927,496 - 51,948,764 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	13	51,927,596 - 51,948,758	NCBI
Celera	13	33,946,444 - 33,967,702 (-)	NCBI		Celera
Cytogenetic Map	13	q14.3	NCBI
HuRef	13	33,768,646 - 33,789,294 (+)	NCBI		HuRef
CHM1_1	13	52,997,571 - 53,018,839 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	13	51,670,301 - 51,692,112 (+)	NCBI		T2T-CHM13v2.0

Ckap2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	22,658,168 - 22,675,835 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	22,658,176 - 22,675,835 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	22,168,149 - 22,185,819 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	22,168,160 - 22,185,819 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	23,278,624 - 23,296,291 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	23,633,994 - 23,651,364 (-)	NCBI		MGSCv36	mm8
Celera	8	23,660,804 - 23,678,492 (-)	NCBI		Celera
Cytogenetic Map	8	A2	NCBI
cM Map	8	11.13	NCBI

Ckap2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955431	5,418,103 - 5,427,463 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955431	5,416,596 - 5,429,465 (-)	NCBI	ChiLan1.0	ChiLan1.0

CKAP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	53,674,979 - 53,699,456 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	52,319,243 - 52,343,729 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	33,371,744 - 33,393,483 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	52,378,273 - 52,399,604 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	52,378,278 - 52,399,608 (+)	Ensembl	panpan1.1		panPan2

CKAP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	134,914 - 190,810 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	135,586 - 150,835 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	254,102 - 309,766 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	237,711 - 293,381 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	237,629 - 253,620 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	118,567 - 174,268 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	133,250 - 188,931 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	201,092 - 256,747 (-)	NCBI		UU_Cfam_GSD_1.0

Ckap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	161,386,331 - 161,397,634 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936565	4,871,414 - 4,881,597 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936565	4,872,142 - 4,896,449 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CKAP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	15,751,808 - 15,768,046 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	11	15,751,717 - 15,767,068 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	16,074,832 - 16,090,294 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CKAP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	30,086,068 - 30,107,491 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	30,086,073 - 30,107,463 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666057	13,705,765 - 13,727,131 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Ckap2
184 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	457
Count of miRNA genes:	233
Interacting mature miRNAs:	274
Transcripts:	ENSRNOT00000029266
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	380245	80345693	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	19004435	75226532	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	25152793	70152793	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	35288870	80288870	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	37752156	82752156	Rat
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	37752156	82752156	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	42396345	84729064	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	52726464	84729064	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	52726464	84729064	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	52726464	84729064	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	55711087	83402471	Rat
1298527	Arunc2	Aerobic running capacity QTL 2	2.9		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	68532716	75029966	Rat

Markers in Region

BE103463

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	69,864,355 - 69,864,510 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	74,778,690 - 74,778,844	NCBI	Rnor6.0
Rnor_5.0	16	74,409,712 - 74,409,866	UniSTS	Rnor5.0
RGSC_v3.4	16	74,518,249 - 74,518,403	UniSTS	RGSC3.4
Celera	16	67,748,991 - 67,749,145	UniSTS
Cytogenetic Map	16	q12.5	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	26	29	22	14	22			51	20	37	1
Low		17	26	17	5	17	4	6	20	14	4	10	4
Below cutoff			2	2		2	4	5	3	1			4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001169139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094590	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094591	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CK596035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EV774137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EV778235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000029266 ⟹ ENSRNOP00000037955

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	69,839,630 - 69,864,913 (+)	Ensembl
Rnor_6.0 Ensembl	16	74,752,655 - 74,779,184 (+)	Ensembl

RefSeq Acc Id:

NM_001169139 ⟹ NP_001162610

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	76,542,114 - 76,567,295 (+)	NCBI
mRatBN7.2	16	69,839,668 - 69,864,850 (+)	NCBI
Rnor_6.0	16	74,752,655 - 74,779,184 (+)	NCBI
Rnor_5.0	16	74,383,677 - 74,410,206 (+)	NCBI
RGSC_v3.4	16	74,492,221 - 74,518,743 (+)	RGD
Celera	16	67,729,052 - 67,749,485 (+)	RGD

Sequence:

show sequence

ATGGCAGAGTCCAGGAAACGCTCCCTTGGCCGGCCTGCGAGGAGTACCTTGCGGGTTCCTCGGG
ACCTGCAGCTGCCCCCGACCAAGAGAGACCAGCCGGCCTTCAGAGAACAAAGAAAAGAAAAACT
CAAGGAATATCTGTTAATACGAAAAACAACGTTTCCATACAAACAAGAGAATCAGATATCCAGA
GATCAGAAAATGGTGACATCTGAGGATCAGGTCCAAGAAGGGAAAAAAGTTGTGAAACTCAAAA
CAGAAGTGGCTGATAAAGAAAATATTGGAAGTATAGTTGAAAAAAACTGCGTTCCATTAAAGGC
TGAAGAAGTAGCCAGCTCAGAAACGCACCACCCAAAGGGTGATGTGCAAGCCGTGCAGCTGTTA
TCCACCGGAGCGGATTTCCCAGGTCAGCCCGTGATGTTAGACCAGGCTTGTCACCATAAAGACA
GTGCAGGGACGCAAGTGACGGCAGAGAAGACGAAGCAAGACACTAACATGTCTAAAAAACGAGT
GCTTGGCTATTATCACGGCCAGATTGTTCAGTCTAAGATCAATTCATTCAGAAAGCTTCCCAGT
GTCAAAGACGAGAGTCTCGCAGCAACCAAGAAACTCCCCACTACTGTGTCTAAAGCCAGGAAGG
CTCACATTGAGCCTGGGAAGGCCGTCAGTGTCAGAGCCTCAAATACAGCTGCTGCCACCAGGTC
TACAGACACTAACTCCGGGAGCGCCTTGTCCAAGAACACACTTGTGCGACCACCTATCCGAAGT
CTCCACAGTAGAACCCACGGCGGGACCCTCGGTGCTGTGAAGCAAGGCCTCGGCGGGACCCTTG
ACAGTGTTACAGTCAGAAAAGAGTCGCTTGAAAAGGAGTCACATCGACCAGAACCGGTCATGTC
TGTTGTCAAAACCAGTTCTTCTCAGGACACAAAAAGAGGCAAGGCCCCACCAAGAAGCATAGCA
TGTAAAGATGTAACCAGGACTAACTCATCTAATGCCAGGCTGACAGGAAAGTCCAGAGATCCTG
ACCAGCGCAGATACACGATCGCAGGAGCGGCTGTCCTTAGATCAGCTCAGCCCAAAGATACCAC
AGCAGACAGGAAAGCTCAGATGACCGACTGGAGAACTGGCAAAGGGAAGGGGCTAAAAAGGCCT
CCTCATTCAGAGGTCACCCAGGCTGAGCCCAAGAGACAAAACGAAAACGCAGTTGGGTCCTTTT
GGACCACCATGGCAGAAGAAGACGAGCAGAGATTATTCACTGAAAAAGTAAACAAAACGATTTC
TGAGTGCCTGAACCTCATTAATAAGGGATGCCCAAAAGAAGAAATTTTAGCTACACTGAATGAC
CTGATTCATAATATTCCAGATGCCAAGAAACTTGTTAAATATTGGATATGTCTTGTACGTATTG
AACCAATCACAAGTCCTATTGAAAATATTATTTCAATCTACGAGAAGGCCATTCTGGCAGGGGC
TCAGCCTATTGAAGAGATGCGACATATAATCATAGATATTCTAACAACGAAGAATCAAGAAAAA
GCCAATTTGGGAGAAAATATTGAGGAGGCTCATGCAACCAAGGAACATATCCAAGAAGTAAATG
TTGAAACTAATCTCGGGTCAGGAAAACCAGAAGAGGAGAATGAACATCATAGAAAAGTTGAGGT
TTACGAAGACAATCAGGACAGCAAAACAGAAGATCCAACCAATGATCTAACAACCCCAGACTCA
AAAGCCGAGGCAGGTTGCCTGATTCGATATAATGTATCTTCTACACCACGCTTGCAAAGTATGA
AAAAGACGCAACATGATAAAAATTCCACATTTAAAGAGCTAAAGTTTCTGACACCCGTGAGACG
TTCGCGCCGCATTCAAGAGAAGACTTTACGACTGCCAGACATGTTAAAAGACCATGACCCTTCC
GTGTCTTCCCTGGAGCAGTTGTCGGAGTTGGGAGGGGATGCTTTTGTTTGCCGCCCTAATGCAG
CCCTGTGCCCTCTGTTCTGTGAGACCGACGTCGTGGAGGAGGAATAGCACTCCTGAGGCCTCAG
CAGTTATGGTTGCCTTGTGTACAACTTTACAATAGGTCTGATGCTGTCTGCATGCCTAAGTATG
ATACAGGTGAACACCAATAGCCTGTTTATTGTGTTTTAAAAATATGTTAGCTATTTCACTTTAC
TAACTACTTTCCGTAAAGAAGCGTAATCAGAAAACGTAGCCTATATAAATTTATATTTTTACAT
TGACTTTGTTCCTAATATGTTTATAATAAATATGTGTGTATAAATATGTATGATGTTCCAATGA
CATTTCATTAATTGAGTGACTTATTTAACGATGGAACTGACTTTAGGACCCAACTGTGGGGCTG
TAGCCAGCTGCCTATGGCGTTTATTTCAACAAATATGTTCTGGGGCTCTCAGATGTGCTCCTAG
TAGAGCACTTGCCTAATGTACAAGGCCCTGGATCTAGTCCTTAGCACCACAAGAAAAACTACTT
TGTAAAATGTCCTTTAACCACAGTAACCAAATATAAACTTAGTTTTTGAAATA

hide sequence

RefSeq Acc Id:

XM_039094590 ⟹ XP_038950518

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	76,542,508 - 76,567,297 (+)	NCBI
mRatBN7.2	16	69,840,023 - 69,864,852 (+)	NCBI

RefSeq Acc Id:

XM_039094591 ⟹ XP_038950519

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	76,542,634 - 76,567,297 (+)	NCBI
mRatBN7.2	16	69,840,203 - 69,864,852 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001162610	(Get FASTA)	NCBI Sequence Viewer
	XP_038950518	(Get FASTA)	NCBI Sequence Viewer
	XP_038950519	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000037955
	ENSRNOP00000037955.4

RefSeq Acc Id:

NP_001162610 ⟸ NM_001169139

- UniProtKB:

D3ZPD0 (UniProtKB/TrEMBL), A6IW82 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAESRKRSLGRPARSTLRVPRDLQLPPTKRDQPAFREQRKEKLKEYLLIRKTTFPYKQENQISR
DQKMVTSEDQVQEGKKVVKLKTEVADKENIGSIVEKNCVPLKAEEVASSETHHPKGDVQAVQLL
STGADFPGQPVMLDQACHHKDSAGTQVTAEKTKQDTNMSKKRVLGYYHGQIVQSKINSFRKLPS
VKDESLAATKKLPTTVSKARKAHIEPGKAVSVRASNTAAATRSTDTNSGSALSKNTLVRPPIRS
LHSRTHGGTLGAVKQGLGGTLDSVTVRKESLEKESHRPEPVMSVVKTSSSQDTKRGKAPPRSIA
CKDVTRTNSSNARLTGKSRDPDQRRYTIAGAAVLRSAQPKDTTADRKAQMTDWRTGKGKGLKRP
PHSEVTQAEPKRQNENAVGSFWTTMAEEDEQRLFTEKVNKTISECLNLINKGCPKEEILATLND
LIHNIPDAKKLVKYWICLVRIEPITSPIENIISIYEKAILAGAQPIEEMRHIIIDILTTKNQEK
ANLGENIEEAHATKEHIQEVNVETNLGSGKPEEENEHHRKVEVYEDNQDSKTEDPTNDLTTPDS
KAEAGCLIRYNVSSTPRLQSMKKTQHDKNSTFKELKFLTPVRRSRRIQEKTLRLPDMLKDHDPS
VSSLEQLSELGGDAFVCRPNAALCPLFCETDVVEEE

hide sequence

RefSeq Acc Id:

ENSRNOP00000037955 ⟸ ENSRNOT00000029266

RefSeq Acc Id:	XP_038950518 ⟸ XM_039094590
- Peptide Label:	isoform X1
- UniProtKB:	A6IW82 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038950519 ⟸ XM_039094591
- Peptide Label:	isoform X1
- UniProtKB:	A6IW82 (UniProtKB/TrEMBL)

Protein Domains

Cytoskeleton-associated protein 2 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZPD0-F1-model_v2	AlphaFold	D3ZPD0	1-676	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700193

Promoter ID:

EPDNEW_R10717

Type:

initiation region

Name:

Ckap2_1

Description:

cytoskeleton associated protein 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	74,752,677 - 74,752,737	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311631	AgrOrtholog
BioCyc Gene	G2FUF-10862	BioCyc
Ensembl Genes	ENSRNOG00000024650	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000029266	ENTREZGENE
	ENSRNOT00000029266.6	UniProtKB/TrEMBL
InterPro	CKAP2_C	UniProtKB/TrEMBL
	CKAP2_fam	UniProtKB/TrEMBL
KEGG Report	rno:306575	UniProtKB/TrEMBL
NCBI Gene	306575	ENTREZGENE
PANTHER	CYTOSKELETON-ASSOCIATED PROTEIN 2	UniProtKB/TrEMBL
	PTHR16076	UniProtKB/TrEMBL
Pfam	CKAP2_C	UniProtKB/TrEMBL
PhenoGen	Ckap2	PhenoGen
RatGTEx	ENSRNOG00000024650	RatGTEx
UniProt	A6IW82	ENTREZGENE, UniProtKB/TrEMBL
	D3ZPD0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Ckap2	cytoskeleton associated protein 2	Ckap2_predicted	cytoskeleton associated protein 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Ckap2_predicted	cytoskeleton associated protein 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar