Rtn2 (reticulon 2) - Rat Genome Database

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Gene: Rtn2 (reticulon 2) Rattus norvegicus
Analyze
Symbol: Rtn2
Name: reticulon 2
RGD ID: 1303245
Description: Acts upstream of or within protein transport. Located in cell surface and endoplasmic reticulum. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 12. Orthologous to human RTN2 (reticulon 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: formerly RTN2w; neuroendocrine-specific protein-like 1; neuroendocrine-specific protein-like I; NSP-like 1; NSP-like protein 1; NSP-like protein I; NSPLI; reticulon 2 (Z-band associated protein); reticulon-2; RTN2-B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,063,124 - 88,076,082 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl188,063,119 - 88,076,043 (+)EnsemblGRCr8
mRatBN7.2178,935,056 - 78,948,069 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,935,104 - 78,948,069 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx184,324,335 - 84,337,063 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,881,890 - 92,894,670 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,079,422 - 86,092,150 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd186,683,240 - 86,696,028 (+)NCBI
Lyon_Normotensive191,820,261 - 91,833,045 (+)NCBI
Lyon_Hypertensive188,363,159 - 88,375,881 (+)NCBI
F344_StmMcwi186,809,192 - 86,821,984 (+)NCBI
Rnor_6.0180,195,594 - 80,208,449 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,195,532 - 80,208,448 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.0181,462,077 - 81,474,932 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4178,647,099 - 78,660,389 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera173,397,564 - 73,410,355 (+)NCBICelera
RGSC_v3.1178,725,036 - 78,738,491 (+)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bisphenol F  (EXP,ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
calcitriol  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
D-glucose  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
diisononyl phthalate  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
ethanol  (ISO)
fructose  (ISO)
gallic acid  (ISO)
gentamycin  (EXP)
glucose  (ISO)
indometacin  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (EXP)
picoxystrobin  (ISO)
pioglitazone  (ISO)
potassium dichromate  (ISO)
propanal  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sulforaphane  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thalidomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trametinib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1. Liu Y, etal., J Biol Chem. 2008 Mar 7;283(10):6561-71. doi: 10.1074/jbc.M708096200. Epub 2007 Dec 20.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12832288   PMID:19720795   PMID:22232211  


Genomics

Comparative Map Data
Rtn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,063,124 - 88,076,082 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl188,063,119 - 88,076,043 (+)EnsemblGRCr8
mRatBN7.2178,935,056 - 78,948,069 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,935,104 - 78,948,069 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx184,324,335 - 84,337,063 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,881,890 - 92,894,670 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,079,422 - 86,092,150 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd186,683,240 - 86,696,028 (+)NCBI
Lyon_Normotensive191,820,261 - 91,833,045 (+)NCBI
Lyon_Hypertensive188,363,159 - 88,375,881 (+)NCBI
F344_StmMcwi186,809,192 - 86,821,984 (+)NCBI
Rnor_6.0180,195,594 - 80,208,449 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,195,532 - 80,208,448 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.0181,462,077 - 81,474,932 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4178,647,099 - 78,660,389 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera173,397,564 - 73,410,355 (+)NCBICelera
RGSC_v3.1178,725,036 - 78,738,491 (+)NCBI
Cytogenetic Map1q21NCBI
RTN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,485,294 - 45,497,047 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,485,292 - 45,497,055 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh371945,988,552 - 46,000,305 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361950,680,390 - 50,692,153 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341950,680,389 - 50,692,153NCBI
Celera1942,794,649 - 42,806,419 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,418,168 - 42,429,756 (-)NCBIHuRef
CHM1_11945,991,794 - 46,003,559 (-)NCBICHM1_1
T2T-CHM13v2.01948,312,543 - 48,326,854 (-)NCBIT2T-CHM13v2.0
Rtn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,016,549 - 19,030,089 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,016,505 - 19,030,178 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38719,282,624 - 19,296,164 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,282,624 - 19,296,160 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37719,868,016 - 19,881,509 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36718,441,189 - 18,454,682 (+)NCBIMGSCv36mm8
Celera716,679,800 - 16,713,582 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.54NCBI
Rtn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555741,071 - 21,117 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_0049555741,543 - 11,476 (-)NCBIChiLan1.0ChiLan1.0
RTN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22051,645,690 - 51,658,924 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,517,190 - 53,530,413 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,434,085 - 42,446,862 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,030,708 - 51,043,404 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1951,030,708 - 51,043,404 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
Rtn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap11510,545,506 - 10,553,920 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_02440934917,567,224 - 17,575,639 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,913,842 - 1,922,772 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,913,852 - 1,922,982 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RTN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,854,998 - 51,875,169 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.1651,855,844 - 51,864,753 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RTN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap1612,370,854 - 12,383,977 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366607318,551,246 - 18,564,389 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1638,931,473 - 38,943,057 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl638,931,348 - 38,942,886 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Rtn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249072,345,223 - 2,350,844 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046249072,344,134 - 2,352,199 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl296,352,543 - 6,361,904 (-)Ensembl
Rtn2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12171,324,444 - 171,336,284 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in Rtn2
188 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:41
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000022528
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
266 156 730 1586 4053 810 1526 132 674 486 656 152 5124 2575 449 3970 38 1335 728 907 160 158

Sequence


Ensembl Acc Id: ENSRNOT00000022528   ⟹   ENSRNOP00000022528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl188,063,119 - 88,076,043 (+)Ensembl
mRatBN7.2 Ensembl178,935,104 - 78,948,030 (+)Ensembl
Rnor_6.0 Ensembl180,195,532 - 80,208,448 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101499   ⟹   ENSRNOP00000092461
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl188,063,782 - 88,076,043 (+)Ensembl
mRatBN7.2 Ensembl178,943,076 - 78,948,069 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115756   ⟹   ENSRNOP00000092160
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl188,071,096 - 88,075,994 (+)Ensembl
mRatBN7.2 Ensembl178,943,077 - 78,947,979 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000171374   ⟹   ENSRNOP00000112016
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl188,064,359 - 88,076,043 (+)Ensembl
RefSeq Acc Id: NM_201562   ⟹   NP_963856
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,063,292 - 88,076,082 (+)NCBI
mRatBN7.2178,935,277 - 78,948,069 (+)NCBI
Dahl_SR_JrHsd186,683,240 - 86,696,028 (+)NCBI
Lyon_Normotensive191,820,261 - 91,833,045 (+)NCBI
Lyon_Hypertensive188,363,159 - 88,375,881 (+)NCBI
F344_StmMcwi186,809,192 - 86,821,984 (+)NCBI
Rnor_6.0180,195,594 - 80,208,449 (+)NCBI
Rnor_5.0181,462,077 - 81,474,932 (+)NCBI
RGSC_v3.4178,647,099 - 78,660,389 (+)RGD
Celera173,397,564 - 73,410,355 (+)RGD
Sequence:
RefSeq Acc Id: XM_017589116   ⟹   XP_017444605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,071,002 - 88,075,996 (+)NCBI
mRatBN7.2178,942,989 - 78,948,066 (+)NCBI
Rnor_6.0180,203,409 - 80,208,367 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039111299   ⟹   XP_038967227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,063,124 - 88,071,088 (+)NCBI
mRatBN7.2178,935,056 - 78,943,030 (+)NCBI
RefSeq Acc Id: NP_963856   ⟸   NM_201562
- UniProtKB: F1LM00 (UniProtKB/Swiss-Prot),   Q6WN19 (UniProtKB/TrEMBL),   A0ABK0LZQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444605   ⟸   XM_017589116
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000022528   ⟸   ENSRNOT00000022528
RefSeq Acc Id: XP_038967227   ⟸   XM_039111299
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000092461   ⟸   ENSRNOT00000101499
Ensembl Acc Id: ENSRNOP00000092160   ⟸   ENSRNOT00000115756
Ensembl Acc Id: ENSRNOP00000112016   ⟸   ENSRNOT00000171374
Protein Domains
Reticulon

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6WN19-F1-model_v2 AlphaFold Q6WN19 1-469 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303245 AgrOrtholog
BioCyc Gene G2FUF-60516 BioCyc
Ensembl Genes ENSRNOG00000016603 Ensembl, ENTREZGENE
  ENSRNOG00055032929 UniProtKB/Swiss-Prot
  ENSRNOG00060032928 UniProtKB/Swiss-Prot
  ENSRNOG00065031307 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000101499 ENTREZGENE
  ENSRNOT00055056963 UniProtKB/Swiss-Prot
  ENSRNOT00060057097 UniProtKB/Swiss-Prot
  ENSRNOT00065054028 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.2480 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:8370402 IMAGE-MGC_LOAD
InterPro Reticulon UniProtKB/Swiss-Prot
  RTN1-4 UniProtKB/Swiss-Prot
KEGG Report rno:308410 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156538 IMAGE-MGC_LOAD
NCBI Gene 308410 ENTREZGENE
PANTHER RETICULON-2 UniProtKB/Swiss-Prot
  RETICULON-LIKE PROTEIN UniProtKB/Swiss-Prot
Pfam Reticulon UniProtKB/Swiss-Prot
PhenoGen Rtn2 PhenoGen
PROSITE RETICULON UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016603 RatGTEx
  ENSRNOG00055032929 RatGTEx
  ENSRNOG00060032928 RatGTEx
  ENSRNOG00065031307 RatGTEx
UniProt A0A8I6AD60_RAT UniProtKB/TrEMBL
  A0A8I6AVP6_RAT UniProtKB/TrEMBL
  A0ABK0LZQ6 ENTREZGENE, UniProtKB/TrEMBL
  A0ACJ1LA34_RAT UniProtKB/TrEMBL
  F1LM00 ENTREZGENE
  Q6WN19 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary F1LM00 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-30 Rtn2  reticulon 2  Rtn2  reticulon 2 (Z-band associated protein)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-30 Rtn2        Symbol and Name status set to provisional 70820 PROVISIONAL