Sec22a (SEC22 homolog A, vesicle trafficking protein) - Rat Genome Database

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Gene: Sec22a (SEC22 homolog A, vesicle trafficking protein) Ictidomys tridecemlineatus
Analyze
Symbol: Sec22a
Name: SEC22 homolog A, vesicle trafficking protein
RGD ID: 12690621
Description: INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); ASSOCIATED WITH alkaptonuria (ortholog); familial hypocalciuric hypercalcemia (ortholog); Primary Lymphedema with Myelodysplasia (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SEC22 vesicle trafficking protein homolog A; vesicle-trafficking protein SEC22a
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602127,998,029 - 128,073,994 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367251,906,362 - 1,975,567 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367251,906,304 - 1,982,413 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Sec22a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602127,998,029 - 128,073,994 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367251,906,362 - 1,975,567 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367251,906,304 - 1,982,413 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC22A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383123,201,943 - 123,274,136 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3123,201,927 - 123,274,136 (+)EnsemblGRCh38hg38GRCh38
GRCh373122,920,790 - 122,992,983 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363124,403,465 - 124,474,050 (+)NCBINCBI36Build 36hg18NCBI36
Build 343124,403,498 - 124,474,043NCBI
Celera3121,327,594 - 121,400,083 (+)NCBICelera
Cytogenetic Map3q21.1NCBI
HuRef3120,294,056 - 120,366,197 (+)NCBIHuRef
CHM1_13122,884,472 - 122,956,673 (+)NCBICHM1_1
T2T-CHM13v2.03125,922,006 - 125,994,223 (+)NCBIT2T-CHM13v2.0
Sec22a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391635,131,505 - 35,184,222 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1635,131,501 - 35,184,288 (-)EnsemblGRCm39 Ensembl
GRCm381635,311,131 - 35,363,929 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1635,311,131 - 35,363,918 (-)EnsemblGRCm38mm10GRCm38
MGSCv371635,311,217 - 35,364,004 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361635,230,878 - 35,283,665 (-)NCBIMGSCv36mm8
Celera1635,780,189 - 35,832,978 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1625.21NCBI
Sec22a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81178,907,552 - 78,967,575 (+)NCBIGRCr8
mRatBN7.21165,402,583 - 65,462,329 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1165,402,684 - 65,462,319 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1174,224,928 - 74,284,604 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01166,887,201 - 66,946,879 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01165,918,478 - 65,978,160 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01168,633,080 - 68,686,553 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,633,160 - 68,686,548 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,720,693 - 71,777,816 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,267,960 - 67,281,677 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11167,325,548 - 67,338,768 (+)NCBI
Celera1164,862,976 - 64,921,131 (+)NCBICelera
Cytogenetic Map11q22NCBI
Sec22a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542722,388,827 - 22,456,149 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542722,389,552 - 22,456,149 (+)NCBIChiLan1.0ChiLan1.0
SEC22A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22121,156,424 - 121,227,462 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13121,161,201 - 121,230,169 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03120,299,636 - 120,370,517 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13127,202,974 - 127,273,475 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3127,203,060 - 127,271,841 (+)Ensemblpanpan1.1panPan2
SEC22A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13326,266,476 - 26,336,544 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3326,267,429 - 26,333,831 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3326,288,952 - 26,357,789 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03326,499,748 - 26,568,641 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3326,499,814 - 26,573,932 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13326,295,295 - 26,364,254 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03326,339,641 - 26,408,888 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03326,898,550 - 26,967,635 (+)NCBIUU_Cfam_GSD_1.0
SEC22A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13137,170,961 - 137,250,550 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113137,175,790 - 137,250,698 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213146,719,530 - 146,793,673 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEC22A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12257,597,146 - 57,666,370 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2257,597,880 - 57,669,151 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041108,675,852 - 108,760,936 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec22a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249121,531,620 - 1,628,265 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000000042   ⟹   ENSSTOP00000000036
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367251,906,362 - 1,975,567 (-)Ensembl
RefSeq Acc Id: XM_013364568   ⟹   XP_013220022
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602127,998,029 - 128,073,994 (-)NCBI
SpeTri2.0NW_0049367251,906,304 - 1,982,413 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735637   ⟹   XP_021591312
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602127,998,029 - 128,073,994 (-)NCBI
SpeTri2.0NW_0049367251,906,304 - 1,982,413 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013220022 (Get FASTA)   NCBI Sequence Viewer  
  XP_021591312 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000000036.3
GenBank Protein KAG3271328 (Get FASTA)   NCBI Sequence Viewer  
  KAG3271329 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_013220022   ⟸   XM_013364568
- Peptide Label: isoform X1
- UniProtKB: I3LVV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021591312   ⟸   XM_021735637
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSTOP00000000036   ⟸   ENSSTOT00000000042
Protein Domains
Longin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000042 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000042.3 UniProtKB/TrEMBL
Gene3D-CATH Longin domain UniProtKB/TrEMBL
InterPro Longin-like_dom_sf UniProtKB/TrEMBL
  Longin_dom UniProtKB/TrEMBL
  Sec22a/c UniProtKB/TrEMBL
NCBI Gene Sec22a ENTREZGENE
PANTHER PTHR46258 UniProtKB/TrEMBL
  PTHR46258:SF3 UniProtKB/TrEMBL
Pfam Longin UniProtKB/TrEMBL
PROSITE LONGIN UniProtKB/TrEMBL
SMART Longin UniProtKB/TrEMBL
Superfamily-SCOP SSF64356 UniProtKB/TrEMBL
UniProt I3LVV9 ENTREZGENE, UniProtKB/TrEMBL