Abat (4-aminobutyrate aminotransferase) - Rat Genome Database

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Gene: Abat (4-aminobutyrate aminotransferase) Ictidomys tridecemlineatus
Analyze
Symbol: Abat
Name: 4-aminobutyrate aminotransferase
RGD ID: 12609130
Description: ENCODES a protein that exhibits 4-aminobutyrate transaminase activity (ortholog); protein homodimerization activity (ortholog); succinate-semialdehyde dehydrogenase binding (ortholog); INVOLVED IN cerebellum development (ortholog); copulation (ortholog); exploration behavior (ortholog); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; ASSOCIATED WITH Abnormal Reflexes (ortholog); Alzheimer's disease (ortholog); Anorexia (ortholog); FOUND IN mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 4-aminobutyrate aminotransferase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344109,698,256 - 109,775,982 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365307,543,682 - 7,622,667 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365307,543,743 - 7,621,392 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Abat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344109,698,256 - 109,775,982 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365307,543,682 - 7,622,667 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365307,543,743 - 7,621,392 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABAT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38168,674,617 - 8,784,570 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl168,674,596 - 8,784,575 (+)EnsemblGRCh38hg38GRCh38
GRCh37168,768,474 - 8,878,427 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36168,675,928 - 8,785,933 (+)NCBINCBI36Build 36hg18NCBI36
Build 34168,675,945 - 8,785,932NCBI
Celera168,937,805 - 9,047,806 (+)NCBICelera
Cytogenetic Map16p13.2NCBI
HuRef168,691,116 - 8,800,895 (+)NCBIHuRef
CHM1_1168,768,357 - 8,878,342 (+)NCBICHM1_1
T2T-CHM13v2.0168,707,289 - 8,817,330 (+)NCBIT2T-CHM13v2.0
Abat
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39168,331,293 - 8,439,432 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl168,331,293 - 8,439,432 (+)EnsemblGRCm39 Ensembl
GRCm38168,513,429 - 8,621,568 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl168,513,429 - 8,621,568 (+)EnsemblGRCm38mm10GRCm38
MGSCv37168,513,522 - 8,621,661 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36168,428,810 - 8,536,889 (+)NCBIMGSCv36mm8
Celera169,158,444 - 9,266,822 (+)NCBICelera
Cytogenetic Map16A1NCBI
cM Map164.06NCBI
Abat
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8107,503,351 - 7,599,474 (-)NCBIGRCr8
mRatBN7.2106,996,688 - 7,092,835 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl106,999,819 - 7,092,835 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1011,705,905 - 11,800,150 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01011,202,332 - 11,296,694 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0106,853,860 - 6,945,716 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0107,093,406 - 7,200,439 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl107,093,405 - 7,200,499 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0105,894,187 - 6,002,068 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4107,040,725 - 7,137,154 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1107,040,724 - 7,137,154 (-)NCBI
Celera105,995,207 - 6,088,218 (-)NCBICelera
Cytogenetic Map10q12NCBI
Abat
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554429,422,849 - 9,516,103 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554429,422,849 - 9,516,054 (-)NCBIChiLan1.0ChiLan1.0
ABAT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2189,201,692 - 9,323,956 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11612,999,815 - 13,108,612 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0167,609,282 - 7,718,049 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1168,850,010 - 8,958,420 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl168,888,178 - 8,958,420 (+)Ensemblpanpan1.1panPan2
ABAT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1633,385,779 - 33,471,348 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl633,376,996 - 33,471,326 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha634,776,452 - 34,862,027 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0633,584,479 - 33,670,069 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl633,584,487 - 33,670,052 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1633,386,823 - 33,472,421 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0633,256,654 - 33,342,147 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0633,678,493 - 33,764,059 (-)NCBIUU_Cfam_GSD_1.0
ABAT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl333,908,970 - 34,015,474 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1333,913,068 - 33,960,804 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2334,642,449 - 34,682,257 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ABAT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.158,274,310 - 8,380,973 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl58,315,952 - 8,379,549 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606821,840,065 - 21,946,865 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abat
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248246,141,213 - 6,202,936 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248246,112,644 - 6,202,936 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000004964   ⟹   ENSSTOP00000004452
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365307,584,660 - 7,618,511 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000036309   ⟹   ENSSTOP00000025501
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365307,543,682 - 7,622,667 (+)Ensembl
RefSeq Acc Id: XM_005327163   ⟹   XP_005327220
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344109,698,256 - 109,775,982 (+)NCBI
SpeTri2.0NW_0049365307,543,743 - 7,621,392 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040278014   ⟹   XP_040133948
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344109,723,709 - 109,775,982 (+)NCBI
RefSeq Acc Id: XM_040278015   ⟹   XP_040133949
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344109,723,709 - 109,775,982 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005327220 (Get FASTA)   NCBI Sequence Viewer  
  XP_040133948 (Get FASTA)   NCBI Sequence Viewer  
  XP_040133949 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000004452.3
  ENSSTOP00000025501.1
GenBank Protein KAG3259199 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005327220   ⟸   XM_005327163
- UniProtKB: A0A287CW46 (UniProtKB/TrEMBL),   I3M573 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040133948   ⟸   XM_040278014
- UniProtKB: A0A287CW46 (UniProtKB/TrEMBL),   I3M573 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040133949   ⟸   XM_040278015
- UniProtKB: A0A287CW46 (UniProtKB/TrEMBL),   I3M573 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000004452   ⟸   ENSSTOT00000004964
RefSeq Acc Id: ENSSTOP00000025501   ⟸   ENSSTOT00000036309


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004949 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004964.3 UniProtKB/TrEMBL
  ENSSTOT00000036309.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/TrEMBL
InterPro 4NH2But_aminotransferase_euk UniProtKB/TrEMBL
  Aminotrans_3 UniProtKB/TrEMBL
  Aminotrans_3_PPA_site UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_small UniProtKB/TrEMBL
NCBI Gene Abat ENTREZGENE
PANTHER 4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL UniProtKB/TrEMBL
  AMINOTRANSFERASE UniProtKB/TrEMBL
Pfam Aminotran_3 UniProtKB/TrEMBL
PIRSF Transaminase_4ab_Lys_Orn UniProtKB/TrEMBL
PROSITE AA_TRANSFER_CLASS_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF53383 UniProtKB/TrEMBL
UniProt A0A287CW46 ENTREZGENE, UniProtKB/TrEMBL
  I3M573 ENTREZGENE, UniProtKB/TrEMBL