Man2b1 (mannosidase alpha class 2B member 1)

Gene: Man2b1 (mannosidase alpha class 2B member 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Man2b1

Name:

mannosidase alpha class 2B member 1

RGD ID:

12576852

Description:

ENCODES a protein that exhibits alpha-mannosidase activity (ortholog); mannose binding (ortholog); INVOLVED IN learning or memory (ortholog); mannose metabolic process (ortholog); ASSOCIATED WITH alpha-mannosidosis (ortholog); Charcot-Marie-Tooth disease dominant intermediate B (ortholog); Craniosynostosis Syndrome, Autosomal Recessive (ortholog); FOUND IN lysosomal lumen (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lysosomal alpha-mannosidase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	208,561,069 - 208,578,396 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936659	1,774,773 - 1,793,670 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936659	1,776,212 - 1,793,651 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alpha-mannosidosis (ISO)

Charcot-Marie-Tooth disease dominant intermediate B (ISO)

Craniosynostosis Syndrome, Autosomal Recessive (ISO)

episodic ataxia type 2 (ISO)

genetic disease (ISO)

glutaric acidemia I (ISO)

IgA glomerulonephritis (ISO)

intellectual disability (ISO)

methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency (ISO)

myoepithelioma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

learning or memory (IEA,ISO)

mannose metabolic process (IEA,ISO)

N-glycan processing (IEA)

oligosaccharide catabolic process (IEA)

protein modification process (IEA)

Cellular Component

extracellular space (IEA)

Golgi membrane (IEA)

intracellular membrane-bounded organelle (IEA)

lysosomal lumen (IEA,ISO)

lysosome (IEA)

nucleoplasm (IEA)

Molecular Function

alpha-mannosidase activity (IEA,ISO)

carbohydrate binding (IEA)

hydrolase activity, acting on glycosyl bonds (IEA)

mannose binding (ISO)

metal ion binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Man2b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	208,561,069 - 208,578,396 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936659	1,774,773 - 1,793,670 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936659	1,776,212 - 1,793,651 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAN2B1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	12,646,512 - 12,666,742 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	12,646,511 - 12,666,742 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	12,757,326 - 12,777,556 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	12,618,322 - 12,638,828 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	12,618,321 - 12,638,828	NCBI
Celera	19	12,647,038 - 12,667,305 (-)	NCBI		Celera
Cytogenetic Map	19	p13.13	NCBI
HuRef	19	12,330,278 - 12,350,679 (-)	NCBI		HuRef
CHM1_1	19	12,757,826 - 12,778,096 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	12,771,019 - 12,791,240 (-)	NCBI		T2T-CHM13v2.0

Man2b1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	85,809,941 - 85,824,215 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	85,809,899 - 85,824,911 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	85,082,730 - 85,098,739 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	85,083,270 - 85,098,282 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	87,607,168 - 87,622,638 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	87,973,435 - 87,987,622 (+)	NCBI		MGSCv36	mm8
Celera	8	89,377,736 - 89,392,568 (+)	NCBI		Celera
Cytogenetic Map	8	C3	NCBI
cM Map	8	41.55	NCBI

Man2b1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	39,959,964 - 39,979,299 (-)	NCBI		GRCr8
mRatBN7.2	19	23,055,092 - 23,074,398 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	23,055,097 - 23,074,389 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	29,877,660 - 29,896,989 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	30,532,022 - 30,551,353 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	32,754,699 - 32,774,034 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	26,196,797 - 26,216,981 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	26,196,837 - 26,216,267 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	37,172,434 - 37,191,891 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	24,711,378 - 24,730,659 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	24,716,204 - 24,735,485 (-)	NCBI
Celera	19	22,613,060 - 22,632,343 (-)	NCBI		Celera
Cytogenetic Map	19	q11	NCBI

Man2b1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	31,743,812 - 31,770,284 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	31,743,813 - 31,770,560 (-)	NCBI	ChiLan1.0	ChiLan1.0

MAN2B1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	17,575,076 - 17,595,722 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	16,575,673 - 16,596,297 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	12,208,319 - 12,228,934 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	12,954,103 - 12,974,056 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	12,954,103 - 12,974,056 (-)	Ensembl	panpan1.1		panPan2

MAN2B1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	49,446,162 - 49,461,812 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	49,319,770 - 49,335,161 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	49,964,867 - 49,980,270 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	49,964,838 - 49,985,978 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	49,175,662 - 49,191,234 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	49,602,404 - 49,618,026 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	49,844,716 - 49,860,091 (+)	NCBI		UU_Cfam_GSD_1.0

MAN2B1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	66,329,045 - 66,348,056 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	66,329,051 - 66,347,051 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	66,706,800 - 66,724,791 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAN2B1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	11,334,639 - 11,355,391 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	11,334,752 - 11,355,334 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	8,442,103 - 8,462,838 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Man2b1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624901	285,978 - 307,249 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624901	285,981 - 307,177 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005336186	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021733890	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000033737 ⟹ ENSSTOP00000024795

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936659	1,774,773 - 1,793,670 (-)	Ensembl

RefSeq Acc Id:

XM_005336186 ⟹ XP_005336243

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	208,561,070 - 208,578,396 (+)	NCBI
SpeTri2.0	NW_004936659	1,776,212 - 1,793,651 (-)	NCBI

Sequence:

show sequence

ATTGGAGGCGTCCGGGAAGCCCCCAGGAGACCGCGGCGGTGGCGGAGCTATGGGTCGCCGCGCG
CAGGCTTCGTGGGTCTGCGCTGGCGGCTGCCAGGACGCCGCCGAGCCCTGGGTGAACTCCCGCG
CCCTGCGTGCGCCGCTCCTGCCTGTCTTTCTCTTTTTGCTGCTGCTGGCGGCTCCGGGCGCTCG
AGCCGCCGGATACGAGACATGCCCGAGAGTGAAGCCAAACAAGCTCAATGTACACTTGGTGGCC
CACACACATGACGACGTGGGCTGGCTCAAGACCGTGGACCAGTATTTCTATGGCATCCACAATG
AAATCCAGCACGCGGGTGTGCAGTACATCCTAGACTCGGTGATCTCCGCTCTCCAGGAGGATCC
CAACCGTCGCTTCATCTATGTGGAAATTGCTTTCTTCTCTCGTTGGTGGCACCAACAGACAAAT
GCAACACAGGAAATCGTGAGGAATCTGGTGCGTCAGGGGCGCCTGGAGTTTGTCAACGGTGGCT
GGGTGATGAACGATGAGGCCACCACATACTACGGGGCCATCGTGGACCAGATGACACTTGGGCT
GCGCTTTCTAAAAGATACTTTCGGCAATGACGGGCGTCCCCATGTGGCCTGGCACATCGACCCC
TTTGGCCACTCTCGGGAACAGGCCTCCTTGTTCGCCCAGATGGGCTTCGATGGCTTCTTCTTGG
GGCGCATTGATTATGAAGATAAACAGATCCGGGTTGAAAGACGGGAGATGGAGCAGATGTGGAG
GGGCAGCACCAGCCTGAAGCCTCCCACCGCTGACCTCTTCACTGGTGTACTCCCCAACAATTAC
AACCCACCGGAAAAACTATGCTGGGATATGTTGTGTACCGACAGTCCTGTGGTAGAGGATCCCC
GCAGCCCTGAATACAATGCCAAGAGCCTGGTCGATTACTTCCTGAAGCTGGCCACTAGCCAGGG
CCAGCAGTACCGCACCAACCACACCATTATGACCATGGGCTCAGACTTCCAGTATGAGAACGCC
AACCTGTGGTTCAAGAACCTTGACAAGCTCATCCGGCTGGTCAATGCTCAGCAGGCAAACGGGA
GCGGGATCCATGTTCTCTACTCCACCCCGGCTTGTTACCTCTGGGAGCTGCACAAGGCCAACCT
CACCTGGTCGGTGAAAAAGGACGACTTCTTCCCTTACGCTGACGGCCCGCACATGTTCTGGACT
GGCTTTTATACCAGCAGGCCGGCCCTCAAACGCTTCGAGCGCCTCAGTTACAAATTCCTGCAGG
TGTGCAACCAGCTGGAGGCGCTGGCGGGTCCTGCGGCCAGCCAAGGACCCTATGGCTCGGGAAA
CTGTGCGCCTCTGAATGAGGCGATGGCGGTGCTCCAGCACCACGACGCAGTCACCGGCACCGCT
AGGCAACTCGTGGCGGAGGATTATGCGCGGCAGCTGTCCGAAGGCTGGGGTCCCAGCGAGGTTC
TCCTGAGCAATGCGTTGGCGCGGCTCAGCGGCTCCAAGAAGACCTTCACGTTCTGCCGCGACCT
CAACATCAGCATCTGCCCGCTCAGCCAGAAGTCAGCGAGTTTCCAGGTCATCCTTTATAACCCC
CTGGGGCGGAAGGTGGATCATATGGTGCGGCTGCCAGTCAGCAAGAGCAGTTTCCACGTGAAGG
ATCCCAGTGGCCAGACTGTGCCCAATAGTGTGGTGGTGGTTCCCAGTGCTGAGCCTCAGGAGCA
CTACCCAGAGCTAGTTTTCTCTGCATCAGTGCCTGCCTTGGGCTTCAGCATCTACTCAGTAACC
AAGATTTCTCACCAGAAGCCCTCGATCCCTCTTCCAAATTCTATTTCCCGGAAGTTCAGGTCCC
GGTTCCGTGTCTTAGCAATTGAAAATGAGTACATTCGGGCCACATTCAACCCTGACACAGGGTT
CTTGACAGAGATCAGGAACAAGGACAAGAATCTCCTGTTACCTGTGAACCAATCCTTCTTCTGG
TATGGTGCCAGTTCAGGTGATCTGGAAAGCTGGCAGACCTCTGGGGCCTACATCTTCAGACCTG
AAGGACGGAAACCATATCCTGTGAGCCACTATGCTCAGATCCGCCTGGTGAAGACACCTTTGGT
GCAGGAGCTACACCAGAATTTTTCAGCCTGGTGTTCCCAGGTGGTTCGCCTGTACCAGGGACAG
CGTCACCTGGAGCTGGAGTGGACAGTGGGGCCGATACCTGTGGGTGAAGGCTGGGGAAAGGAGG
TCATCAGTCGCTTTGACACACCGCTGAAGACAAATGGGCTCTTCTACACAGACAGCAATGGCCG
GGAGATACTGCAGAGAAAGCGGGATTATCGGCCCACCTGGGAACTGGACCTGTGGGAGCCTGTG
GCCGGAAACTACTATCCTGTCAACACTCGGATTTACATCAAGGATAGGAATATGCAGCTGACAG
TGCTCACTGACCGCTCCCAGGGGGGCAGCAGCTTGGGAAATGGCTCGCTGGAGCTCATGGTGCA
CCGAAGGCTGGTGAAAGATGACGGTCGTGGGTTACAGGAGCCACTGAAAGAGAACGGGTCTGGA
CTGGTGGCACGAGGGCGCCACCTCGTGCTGCTGGACAGGGTGGGTGAGGCGGCCGCTGGGCACC
GGCTGCTGGCGGAGAAAGAGGTCCTAGCTCCGCAGGTGGTGTTAGCCCCAGATGGCGGAGCCCT
CTACCACCCCCAGGCCACCCCACGCATGCAGTTCTCAGGACTGCGCCGAGAGCTGCCGCCCTCA
GTGCACCTGCTCACGCTGGCCCGCTGGGGCCTCAACAAGCTGCTGCTGCGCTTTGAACATCAGT
TCACAGTGTGGGAGGATTCAGGCCGCAACCTGAGCGCCCCTGTCACCTTGGACTTGCGGGATCT
GTTCTCCAGCTTCACCATTACCCACGTGCAAGAGACCACGCTGGCAGCCAACCAGCCCCGTGCC
AGTGCCTCGAGGCTCCAGTGGACAGTAAAGGATGGTCCCACTCCCCACCCTGCACCATTCACAC
TGGACCCATCCTCCATCACCCTACAGCCCATGGAGATCCGCACCTTTGTGGCCTTAGTCCAATG
GAAGGGCGGCTGGACCCTCTAGGAGGGCCCCTTCAGTACCTGAACCCCAGCTCTGGGGGAGAGG
GCAGACTCCCTTCTCAATCTGCTGCTGCCGCCTACAACTGCCATTAAAATGCCACCACTGCCTG
GTACAGTGGTGCACGCCTGTAATCCCAGTAGCTCAGGAGTCTGAGTCAGGAGGATGGCAAGTTC
AAATCTAGCCTCAGCAACTTGGCAAGGCCCTAAGCAACTTAGTGACACCCTGTTTTAAAATAAA
AAGTTTTTTTTAAAAAAAAAATGGGCAAGGGATGTGGCTCAGTGATTAAGCACCCCTGGGTTCA
ATCTGATACAACCTAATAAATTAAAATAT

hide sequence

RefSeq Acc Id:

XM_021733890 ⟹ XP_021589565

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	208,561,069 - 208,578,396 (+)	NCBI
SpeTri2.0	NW_004936659	1,776,212 - 1,793,651 (-)	NCBI

Sequence:

show sequence

ATTGGAGGCGTCCGGGAAGCCCCCAGGAGACCGCGGCGGTGGCGGAGCTATGGGTCGCCGCGCG
CAGGCTTCGTGGGTCTGCGCTGGCGGCTGCCAGGACGCCGCCGAGCCCTGGGTGAACTCCCGCG
CCCTGCGTGCGCCGCTCCTGCCTGTCTTTCTCTTTTTGCTGCTGCTGGCGGCTCCGGGCGCTCG
AGCCGCCGGATACGAGACATGCCCGAGAGTGAAGCCAAACAAGCTCAATGTACACTTGGTGGCC
CACACACATGACGACGTGGGCTGGCTCAAGACCGTGGACCAGTATTTCTATGGCATCCACAATG
AAATCCAGCACGCGGGTGTGCAGTACATCCTAGACTCGGTGATCTCCGCTCTCCAGGAGGATCC
CAACCGTCGCTTCATCTATGTGGAAATTGCTTTCTTCTCTCGTTGGTGGCACCAACAGACAAAT
GCAACACAGGAAATCGTGAGGAATCTGGTGCGTCAGGGGCGCCTGGAGTTTGTCAACGGTGGCT
GGGTGATGAACGATGAGGCCACCACATACTACGGGGCCATCGTGGACCAGATGACACTTGGGCT
GCGCTTTCTAAAAGATACTTTCGGCAATGACGGGCGTCCCCATGTGGCCTGGCACATCGACCCC
TTTGGCCACTCTCGGGAACAGGCCTCCTTGTTCGCCCAGATGGGCTTCGATGGCTTCTTCTTGG
GGCGCATTGATTATGAAGATAAACAGATCCGGGTTGAAAGACGGGAGATGGAGCAGATGTGGAG
GGGCAGCACCAGCCTGAAGCCTCCCACCGCTGACCTCTTCACTGGTGTACTCCCCAACAATTAC
AACCCACCGGAAAAACTATGCTGGGATATGTTGTGTACCGACAGTCCTGTGGTAGAGGATCCCC
GCAGCCCTGAATACAATGCCAAGAGCCTGGTCGATTACTTCCTGAAGCTGGCCACTAGCCAGGG
CCAGCAGTACCGCACCAACCACACCATTATGACCATGGGCTCAGACTTCCAGTATGAGAACGCC
AACCTGTGGTTCAAGAACCTTGACAAGCTCATCCGGCTGGTCAATGCTCAGCAGGCAAACGGGA
GCGGGATCCATGTTCTCTACTCCACCCCGGCTTGTTACCTCTGGGAGCTGCACAAGGCCAACCT
CACCTGGTCGGTGAAAAAGGACGACTTCTTCCCTTACGCTGACGGCCCGCACATGTTCTGGACT
GGCTTTTATACCAGCAGGCCGGCCCTCAAACGCTTCGAGCGCCTCAGTTACAAATTCCTGCAGG
TGTGCAACCAGCTGGAGGCGCTGGCGGGTCCTGCGGCCAGCCAAGGACCCTATGGCTCGGGAAA
CTGTGCGCCTCTGAATGAGGCGATGGCGGTGCTCCAGCACCACGACGCAGTCACCGGCACCGCT
AGGCAACTCGTGGCGGAGGATTATGCGCGGCAGCTGTCCGAAGGCTGGGGTCCCAGCGAGGTTC
TCCTGAGCAATGCGTTGGCGCGGCTCAGCGGCTCCAAGAAGACCTTCACGTTCTGCCGCGACCT
CAACATCAGCATCTGCCCGCTCAGCCAGAAGTCAGCGAGTTTCCAGGTCATCCTTTATAACCCC
CTGGGGCGGAAGGTGGATCATATGGTGCGGCTGCCAGTCAGCAAGAGCAGTTTCCACGTGAAGG
ATCCCAGTGGCCAGACTGTGCCCAATAGTGTGGTGGTGGTTCCCAGTGCTGAGCCTCAGGAGCA
CTACCCAGAGCTAGTTTTCTCTGCATCAGTGCCTGCCTTGGGCTTCAGCATCTACTCAGTAACC
AAGATTTCTCACCAGAAGCCCTCGATCCCTCTTCCAAATTCTATTTCCCGGAAGTTCAGGTCCC
GGTTCCGTGTCTTAGCAATTGAAAATGAGTACATTCGGGCCACATTCAACCCTGACACAGGGTT
CTTGACAGAGATCAGGAACAAGGACAAGAATCTCCTGTTACCTGTGAACCAATCCTTCTTCTGG
TATGGTGCCAGTTCAGGTGATCTGGAAAGCTGGCAGACCTCTGGGGCCTACATCTTCAGACCTG
AAGGACGGAAACCATATCCTACACCTTTGGTGCAGGAGCTACACCAGAATTTTTCAGCCTGGTG
TTCCCAGGTGGTTCGCCTGTACCAGGGACAGCGTCACCTGGAGCTGGAGTGGACAGTGGGGCCG
ATACCTGTGGGTGAAGGCTGGGGAAAGGAGGTCATCAGTCGCTTTGACACACCGCTGAAGACAA
ATGGGCTCTTCTACACAGACAGCAATGGCCGGGAGATACTGCAGAGAAAGCGGGATTATCGGCC
CACCTGGGAACTGGACCTGTGGGAGCCTGTGGCCGGAAACTACTATCCTGTCAACACTCGGATT
TACATCAAGGATAGGAATATGCAGCTGACAGTGCTCACTGACCGCTCCCAGGGGGGCAGCAGCT
TGGGAAATGGCTCGCTGGAGCTCATGGTGCACCGAAGGCTGGTGAAAGATGACGGTCGTGGGTT
ACAGGAGCCACTGAAAGAGAACGGGTCTGGACTGGTGGCACGAGGGCGCCACCTCGTGCTGCTG
GACAGGGTGGGTGAGGCGGCCGCTGGGCACCGGCTGCTGGCGGAGAAAGAGGTCCTAGCTCCGC
AGGTGGTGTTAGCCCCAGATGGCGGAGCCCTCTACCACCCCCAGGCCACCCCACGCATGCAGTT
CTCAGGACTGCGCCGAGAGCTGCCGCCCTCAGTGCACCTGCTCACGCTGGCCCGCTGGGGCCTC
AACAAGCTGCTGCTGCGCTTTGAACATCAGTTCACAGTGTGGGAGGATTCAGGCCGCAACCTGA
GCGCCCCTGTCACCTTGGACTTGCGGGATCTGTTCTCCAGCTTCACCATTACCCACGTGCAAGA
GACCACGCTGGCAGCCAACCAGCCCCGTGCCAGTGCCTCGAGGCTCCAGTGGACAGTAAAGGAT
GGTCCCACTCCCCACCCTGCACCATTCACACTGGACCCATCCTCCATCACCCTACAGCCCATGG
AGATCCGCACCTTTGTGGCCTTAGTCCAATGGAAGGGCGGCTGGACCCTCTAGGAGGGCCCCTT
CAGTACCTGAACCCCAGCTCTGGGGGAGAGGGCAGACTCCCTTCTCAATCTGCTGCTGCCGCCT
ACAACTGCCATTAAAATGCCACCACTGCCTGGTACAGTGGTGCACGCCTGTAATCCCAGTAGCT
CAGGAGTCTGAGTCAGGAGGATGGCAAGTTCAAATCTAGCCTCAGCAACTTGGCAAGGCCCTAA
GCAACTTAGTGACACCCTGTTTTAAAATAAAAAGTTTTTTTTAAAAAAAAAATGGGCAAGGGAT
GTGGCTCAGTGATTAAGCACCCCTGGGTTCAATCTGATACAACCTAATAAATTAAAATAT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005336243	(Get FASTA)	NCBI Sequence Viewer
	XP_021589565	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000024795.1

RefSeq Acc Id:	XP_005336243 ⟸ XM_005336186
- Peptide Label:	isoform X1
- UniProtKB:	A0A287CTY8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGRRAQASWVCAGGCQDAAEPWVNSRALRAPLLPVFLFLLLLAAPGARAAGYETCPRVKPNKLN VHLVAHTHDDVGWLKTVDQYFYGIHNEIQHAGVQYILDSVISALQEDPNRRFIYVEIAFFSRWW HQQTNATQEIVRNLVRQGRLEFVNGGWVMNDEATTYYGAIVDQMTLGLRFLKDTFGNDGRPHVA WHIDPFGHSREQASLFAQMGFDGFFLGRIDYEDKQIRVERREMEQMWRGSTSLKPPTADLFTGV LPNNYNPPEKLCWDMLCTDSPVVEDPRSPEYNAKSLVDYFLKLATSQGQQYRTNHTIMTMGSDF QYENANLWFKNLDKLIRLVNAQQANGSGIHVLYSTPACYLWELHKANLTWSVKKDDFFPYADGP HMFWTGFYTSRPALKRFERLSYKFLQVCNQLEALAGPAASQGPYGSGNCAPLNEAMAVLQHHDA VTGTARQLVAEDYARQLSEGWGPSEVLLSNALARLSGSKKTFTFCRDLNISICPLSQKSASFQV ILYNPLGRKVDHMVRLPVSKSSFHVKDPSGQTVPNSVVVVPSAEPQEHYPELVFSASVPALGFS IYSVTKISHQKPSIPLPNSISRKFRSRFRVLAIENEYIRATFNPDTGFLTEIRNKDKNLLLPVN QSFFWYGASSGDLESWQTSGAYIFRPEGRKPYPVSHYAQIRLVKTPLVQELHQNFSAWCSQVVR LYQGQRHLELEWTVGPIPVGEGWGKEVISRFDTPLKTNGLFYTDSNGREILQRKRDYRPTWELD LWEPVAGNYYPVNTRIYIKDRNMQLTVLTDRSQGGSSLGNGSLELMVHRRLVKDDGRGLQEPLK ENGSGLVARGRHLVLLDRVGEAAAGHRLLAEKEVLAPQVVLAPDGGALYHPQATPRMQFSGLRR ELPPSVHLLTLARWGLNKLLLRFEHQFTVWEDSGRNLSAPVTLDLRDLFSSFTITHVQETTLAA NQPRASASRLQWTVKDGPTPHPAPFTLDPSSITLQPMEIRTFVALVQWKGGWTL hide sequence

RefSeq Acc Id:

XP_021589565 ⟸ XM_021733890

- Peptide Label:

isoform X2

- Sequence:

show sequence

MGRRAQASWVCAGGCQDAAEPWVNSRALRAPLLPVFLFLLLLAAPGARAAGYETCPRVKPNKLN
VHLVAHTHDDVGWLKTVDQYFYGIHNEIQHAGVQYILDSVISALQEDPNRRFIYVEIAFFSRWW
HQQTNATQEIVRNLVRQGRLEFVNGGWVMNDEATTYYGAIVDQMTLGLRFLKDTFGNDGRPHVA
WHIDPFGHSREQASLFAQMGFDGFFLGRIDYEDKQIRVERREMEQMWRGSTSLKPPTADLFTGV
LPNNYNPPEKLCWDMLCTDSPVVEDPRSPEYNAKSLVDYFLKLATSQGQQYRTNHTIMTMGSDF
QYENANLWFKNLDKLIRLVNAQQANGSGIHVLYSTPACYLWELHKANLTWSVKKDDFFPYADGP
HMFWTGFYTSRPALKRFERLSYKFLQVCNQLEALAGPAASQGPYGSGNCAPLNEAMAVLQHHDA
VTGTARQLVAEDYARQLSEGWGPSEVLLSNALARLSGSKKTFTFCRDLNISICPLSQKSASFQV
ILYNPLGRKVDHMVRLPVSKSSFHVKDPSGQTVPNSVVVVPSAEPQEHYPELVFSASVPALGFS
IYSVTKISHQKPSIPLPNSISRKFRSRFRVLAIENEYIRATFNPDTGFLTEIRNKDKNLLLPVN
QSFFWYGASSGDLESWQTSGAYIFRPEGRKPYPTPLVQELHQNFSAWCSQVVRLYQGQRHLELE
WTVGPIPVGEGWGKEVISRFDTPLKTNGLFYTDSNGREILQRKRDYRPTWELDLWEPVAGNYYP
VNTRIYIKDRNMQLTVLTDRSQGGSSLGNGSLELMVHRRLVKDDGRGLQEPLKENGSGLVARGR
HLVLLDRVGEAAAGHRLLAEKEVLAPQVVLAPDGGALYHPQATPRMQFSGLRRELPPSVHLLTL
ARWGLNKLLLRFEHQFTVWEDSGRNLSAPVTLDLRDLFSSFTITHVQETTLAANQPRASASRLQ
WTVKDGPTPHPAPFTLDPSSITLQPMEIRTFVALVQWKGGWTL

hide sequence

RefSeq Acc Id:

ENSSTOP00000024795 ⟸ ENSSTOT00000033737

Protein Domains

Glycoside hydrolase family 38 central

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000029598	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000033737.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1270.50	UniProtKB/TrEMBL
	2.60.40.1180	UniProtKB/TrEMBL
	2.60.40.1360	UniProtKB/TrEMBL
	3.20.110.10	UniProtKB/TrEMBL
InterPro	Gal_mutarotase_sf_dom	UniProtKB/TrEMBL
	Glyco_hydro/deAcase_b/a-brl	UniProtKB/TrEMBL
	Glyco_hydro_38_C	UniProtKB/TrEMBL
	Glyco_hydro_38_cen	UniProtKB/TrEMBL
	Glyco_hydro_38_cen_sf	UniProtKB/TrEMBL
	Glyco_hydro_38_N	UniProtKB/TrEMBL
	Glyco_hydro_38_N_sf	UniProtKB/TrEMBL
	Glyco_hydro_57/38_cen_sf	UniProtKB/TrEMBL
	Glyco_hydro_b	UniProtKB/TrEMBL
	Man2a1-like_dom	UniProtKB/TrEMBL
NCBI Gene	Man2b1	ENTREZGENE
PANTHER	ALPHA-MANNOSIDASE	UniProtKB/TrEMBL
	ALPHA-MANNOSIDASE 2-RELATED	UniProtKB/TrEMBL
Pfam	Alpha-mann_mid	UniProtKB/TrEMBL
	Glyco_hydro_38C	UniProtKB/TrEMBL
	Glyco_hydro_38N	UniProtKB/TrEMBL
	Laman-like_dom	UniProtKB/TrEMBL
SMART	Alpha-mann_mid	UniProtKB/TrEMBL
Superfamily-SCOP	SSF74650	UniProtKB/TrEMBL
	SSF88688	UniProtKB/TrEMBL
	SSF88713	UniProtKB/TrEMBL
UniProt	A0A287CTY8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM