Slc12a5 (solute carrier family 12 member 5) - Rat Genome Database

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Gene: Slc12a5 (solute carrier family 12 member 5) Ictidomys tridecemlineatus
Analyze
Symbol: Slc12a5
Name: solute carrier family 12 member 5
RGD ID: 12544185
Description: ENCODES a protein that exhibits ammonium channel activity (ortholog); potassium:chloride symporter activity (ortholog); protein kinase binding (ortholog); INVOLVED IN ammonium transmembrane transport (ortholog); chemical synaptic transmission (ortholog); chloride transport (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 34 (ortholog); epilepsy (ortholog); focal epilepsy (ortholog); FOUND IN dendrite membrane (ortholog); glutamatergic synapse (ortholog); perikaryon (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,546,150 - 191,573,184 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365146,998,044 - 7,026,767 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365146,999,793 - 7,027,094 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Slc12a5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,546,150 - 191,573,184 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365146,998,044 - 7,026,767 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365146,999,793 - 7,027,094 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC12A5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382046,021,686 - 46,060,150 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2046,021,690 - 46,060,150 (+)EnsemblGRCh38hg38GRCh38
GRCh372044,650,325 - 44,688,789 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362044,091,245 - 44,122,196 (+)NCBINCBI36Build 36hg18NCBI36
Build 342044,091,244 - 44,122,196NCBI
Celera2041,361,790 - 41,400,248 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2041,391,623 - 41,430,078 (+)NCBIHuRef
CHM1_12044,552,972 - 44,591,426 (+)NCBICHM1_1
T2T-CHM13v2.02047,757,715 - 47,796,165 (+)NCBIT2T-CHM13v2.0
Slc12a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,802,766 - 164,841,651 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,802,722 - 164,841,651 (+)EnsemblGRCm39 Ensembl
GRCm382164,960,846 - 164,999,731 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,960,802 - 164,999,731 (+)EnsemblGRCm38mm10GRCm38
MGSCv372164,793,488 - 164,825,231 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362164,659,524 - 164,690,936 (+)NCBIMGSCv36mm8
Celera2170,905,292 - 170,937,000 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.28NCBI
Slc12a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83174,115,833 - 174,155,112 (+)NCBIGRCr8
mRatBN7.23153,696,517 - 153,735,801 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,696,517 - 153,735,765 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,505,210 - 157,544,609 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03166,004,181 - 166,043,578 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,747,957 - 163,787,354 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,433,303 - 161,465,078 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,425,988 - 161,462,879 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,617,776 - 167,649,551 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43156,006,017 - 156,037,915 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13155,912,052 - 155,943,951 (+)NCBI
Celera3152,309,197 - 152,341,061 (+)NCBICelera
Cytogenetic Map3q42NCBI
Slc12a5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544511,252,732 - 11,291,501 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544511,252,732 - 11,290,890 (-)NCBIChiLan1.0ChiLan1.0
SLC12A5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22151,761,634 - 51,800,013 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12051,754,742 - 51,793,119 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02042,359,005 - 42,397,412 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12043,445,193 - 43,483,132 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,445,182 - 43,483,132 (+)Ensemblpanpan1.1panPan2
SLC12A5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,285,773 - 33,322,885 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,285,852 - 33,321,567 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,812,617 - 32,849,088 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02433,996,109 - 34,032,786 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2433,996,183 - 34,031,468 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,254,354 - 33,290,810 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,369,649 - 33,406,360 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02433,908,853 - 33,945,337 (+)NCBIUU_Cfam_GSD_1.0
SLC12A5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,192,075 - 48,230,661 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11748,192,072 - 48,230,674 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21753,839,701 - 53,876,239 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC12A5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,823,141 - 17,854,996 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl217,825,676 - 17,854,950 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605066,458,116 - 66,497,517 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc12a5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247908,537,185 - 8,576,861 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247908,539,103 - 8,576,877 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021726313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010003700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000006434   ⟹   ENSSTOP00000005751
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365147,000,217 - 7,021,094 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000037888   ⟹   ENSSTOP00000029860
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365146,999,801 - 7,026,767 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000040708   ⟹   ENSSTOP00000024266
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365146,998,044 - 7,026,674 (-)Ensembl
RefSeq Acc Id: XM_021726313   ⟹   XP_021581988
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640191,546,150 - 191,573,184 (-)NCBI
SpeTri2.0NW_0049365146,999,793 - 7,027,094 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021581988 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000005751.3
  ENSSTOP00000024266.1
  ENSSTOP00000029860.1
GenBank Protein KAG3263526 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021581988   ⟸   XM_021726313
- UniProtKB: A0A287D8H9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000005751   ⟸   ENSSTOT00000006434
RefSeq Acc Id: ENSSTOP00000024266   ⟸   ENSSTOT00000040708
RefSeq Acc Id: ENSSTOP00000029860   ⟸   ENSSTOT00000037888
Protein Domains
Amino acid permease/ SLC12A   SLC12A transporter C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000006405 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000006434.3 UniProtKB/TrEMBL
  ENSSTOT00000037888.1 UniProtKB/TrEMBL
  ENSSTOT00000040708.1 UniProtKB/TrEMBL
Gene3D-CATH Amino acid/polyamine transporter I UniProtKB/TrEMBL
InterPro AA-permease/SLC12A_dom UniProtKB/TrEMBL
  KCL_cotranspt UniProtKB/TrEMBL
  SLC12_C UniProtKB/TrEMBL
  SLC12A_fam UniProtKB/TrEMBL
NCBI Gene Slc12a5 ENTREZGENE
PANTHER PTHR11827 UniProtKB/TrEMBL
  PTHR11827:SF54 UniProtKB/TrEMBL
Pfam AA_permease UniProtKB/TrEMBL
  SLC12 UniProtKB/TrEMBL
PRINTS KCLTRNSPORT UniProtKB/TrEMBL
UniProt A0A287CSJ9_ICTTR UniProtKB/TrEMBL
  A0A287D8H9 ENTREZGENE, UniProtKB/TrEMBL
  I3M7X0_ICTTR UniProtKB/TrEMBL