SLC12A5 (solute carrier family 12 (potassium/chloride transporter), member 5)

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Keyword

Gene: SLC12A5 (solute carrier family 12 (potassium/chloride transporter), member 5) Homo sapiens

Symbol:

SLC12A5

Name:

solute carrier family 12 (potassium/chloride transporter), member 5

Description:

K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

electroneutral potassium-chloride cotransporter 2; erythroid K-Cl cotransporter 2; hKCC2; K-Cl cotransporter 2; KCC2; KIAA1176; neuronal K-Cl cotransporter; OTTHUMP00000031197; solute carrier family 12 member 5

Orthologs:

Mus musculus : Slc12a5 (solute carrier family 12, member 5) MGI
Rattus norvegicus : Slc12a5 (solute carrier family 12 (potassium-chloride transporter), member 5)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	20	44,620,846 - 44,659,304	+	NCBI
Human Genome Assembly HuRef	20	41,391,623 - 41,430,078	+	NCBI
Human Genome Assembly GRCh37	20	44,650,329 - 44,688,789	+	NCBI
Human Genome Assembly Build 36	20	44,091,245 - 44,122,196	+	NCBI
Human Cytogenetic Map	20	q13.12		NCBI
Human Genome Assembly	20	44,091,244 - 44,122,196		NCBI