Cwc15 (CWC15 spliceosome associated protein homolog)

Gene: Cwc15 (CWC15 spliceosome associated protein homolog) Ictidomys tridecemlineatus

Analyze

Symbol:

Cwc15

Name:

CWC15 spliceosome associated protein homolog

RGD ID:

12540871

Description:

ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN mRNA cis splicing, via spliceosome (inferred); mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH ataxia telangiectasia (ortholog); intellectual disability (ortholog); FOUND IN Prp19 complex (ortholog); spliceosomal complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

spliceosome-associated protein CWC15 homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	79,808,542 - 79,815,403 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936674	76,016 - 83,225 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936674	76,022 - 83,110 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

ataxia telangiectasia (ISO)

intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mRNA cis splicing, via spliceosome (IEA)

mRNA processing (IEA)

mRNA splicing, via spliceosome (IEA)

RNA splicing (IEA)

Cellular Component

catalytic step 2 spliceosome (IEA)

mitochondrion (IEA)

nuclear speck (IEA)

nucleus (IEA)

Prp19 complex (IEA,ISO)

spliceosomal complex (IEA,ISO)

U2-type catalytic step 2 spliceosome (IEA)

Molecular Function

protein binding (ISO)

RNA binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

spliceosome pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Cwc15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	79,808,542 - 79,815,403 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936674	76,016 - 83,225 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936674	76,022 - 83,110 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CWC15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	94,962,620 - 94,973,556 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	94,962,620 - 94,973,586 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	94,695,785 - 94,706,720 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	94,335,435 - 94,346,424 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	91,983,570 - 91,994,563 (-)	NCBI		Celera
Cytogenetic Map	11	q21	NCBI
HuRef	11	90,760,716 - 90,771,717 (-)	NCBI		HuRef
CHM1_1	11	94,578,834 - 94,589,825 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	94,969,625 - 94,980,574 (-)	NCBI		T2T-CHM13v2.0

Cwc15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	14,411,876 - 14,421,920 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	14,411,913 - 14,421,873 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	14,500,604 - 14,510,620 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	14,500,617 - 14,510,577 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	14,305,063 - 14,315,064 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	14,251,080 - 14,260,974 (+)	NCBI		MGSCv36	mm8
Celera	9	11,781,357 - 11,791,358 (+)	NCBI		Celera
Cytogenetic Map	9	A2	NCBI
cM Map	9	4.09	NCBI

Cwc15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	19,586,900 - 19,597,817 (+)	NCBI		GRCr8
mRatBN7.2	8	11,305,401 - 11,316,326 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	11,305,424 - 11,316,325 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	15,297,745 - 15,308,545 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	13,595,496 - 13,606,296 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	11,584,554 - 11,595,317 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	12,994,131 - 13,004,958 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	12,994,155 - 13,004,957 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	12,939,478 - 12,950,304 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	11,248,219 - 11,259,120 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	11,248,218 - 11,259,119 (+)	NCBI
Celera	8	12,799,213 - 12,810,079 (+)	NCBI		Celera
Cytogenetic Map	8	q12	NCBI

Cwc15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955605	32,721 - 46,182 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955605	32,721 - 42,981 (+)	NCBI	ChiLan1.0	ChiLan1.0

CWC15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	95,817,527 - 95,827,897 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	96,908,951 - 96,919,321 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	89,977,104 - 89,987,495 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	93,499,411 - 93,509,895 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	93,499,406 - 93,509,827 (-)	Ensembl	panpan1.1		panPan2

CWC15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	6,037,305 - 6,049,124 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	6,038,656 - 6,048,400 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	6,048,475 - 6,059,902 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	6,218,012 - 6,229,451 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	6,218,145 - 6,229,871 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	6,005,692 - 6,017,131 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	6,068,610 - 6,080,048 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	6,116,456 - 6,127,895 (+)	NCBI		UU_Cfam_GSD_1.0

CWC15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	27,035,510 - 27,047,224 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	27,035,501 - 27,047,280 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	30,788,882 - 30,800,635 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CWC15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	86,180,225 - 86,190,445 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	86,179,366 - 86,190,439 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	39,600,706 - 39,611,067 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cwc15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	39,626,956 - 39,663,347 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624735	39,629,120 - 39,640,059 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005337183	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000002480 ⟹ ENSSTOP00000002218

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936674	76,016 - 83,225 (+)	Ensembl

RefSeq Acc Id:

XM_005337183 ⟹ XP_005337240

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	79,808,542 - 79,815,403 (-)	NCBI
SpeTri2.0	NW_004936674	76,022 - 83,110 (+)	NCBI

Sequence:

show sequence

AAGATGACAACAGCAGCCAGGCCGACTTTTGAACCTGCAAGAGGTGGAAGAGGAAAAGGAGAAG
GTGATTTGAGCCAACTCTCAAAGCAGTATTCAAGCAGAGATCTTCCCTCTCATACAAAGATAAA
ATACAGACAAACTACTCAGGATGCCCCTGAAGAGGTTCGTAACCGGGACTTCAGGAGGGAGTTG
GAAGAAAGAGAGAGAGCTGCTGCACGAGAAAAAAATAGAGATCGTCCAACCCGAGAACATACAA
CCTCCTCTTCAGTGTCAAAGAAGCCTCGGCTAGATCAGATTCCTGCTGCCAACCTTGATGCAGA
TGATCCTCTAACAGATGAGGAAGATGAAGATTTTGAAGAGGAGAGTGATGATGATGATACTGCA
GCTCTCCTTGCAGAACTAGAAAAAATTAAAAAAGAAAGAGCAGAAGAGCAGGCCAGGAAGGAAC
AAGAACAAAAAGCTGAAGAAGAGAGAATTCGTATGGAGAACATTCTGAGTGGAAACCCTCTTCT
TAATCTCACTGGCCCTTCCCAGCCTCAGGCCAACTTCAAAGTTAAAAGAAGGTGGGATGACGAT
GTTGTGTTCAAGAACTGCGCAAAAGGTGTAGATGATCAAAAGAAAGACAAAAGATTTGTAAACG
ATACACTTCGATCTGAATTTCACAAAAAATTCATGGAGAAATATATTAAGTAGTACAGTTTTAT
GTGCTTAATTAAAGACTGTAAAATGTTAAGGATCATTTTGATGTTTTTTTTTTTCCTTTTCCGC
CGTCTAAATGGTATATAATAGACTTCCCTAATTTTAAGTTCCAAAGTATCTTTTTCTTTATTGA
GACCTTATTGATAATGGACTTGGGAATAGGTTTAACTCCGTTTCTATTCTCTGAATGTTTTCAA
TCATGTTTTTTTTTTTTAATATGGGAAAAAAGAACCTGCTTGTAATAAATGATTTTAATCTAAA
TAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005337240	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000002218.2
GenBank Protein	KAG3286384	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005337240 ⟸ XM_005337183

- UniProtKB:

I3M0I0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYRQTTQDAPEEVRNRDFRRELE
ERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAANLDADDPLTDEEDEDFEEESDDDDTAA
LLAELEKIKKERAEEQARKEQEQKAEEERIRMENILSGNPLLNLTGPSQPQANFKVKRRWDDDV
VFKNCAKGVDDQKKDKRFVNDTLRSEFHKKFMEKYIK

hide sequence

RefSeq Acc Id:

ENSSTOP00000002218 ⟸ ENSSTOT00000002480

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000002485	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000002480.3	UniProtKB/TrEMBL
InterPro	Cwf_Cwc_15	UniProtKB/TrEMBL
NCBI Gene	Cwc15	ENTREZGENE
PANTHER	PTHR12718	UniProtKB/TrEMBL
	SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG	UniProtKB/TrEMBL
Pfam	Cwf_Cwc_15	UniProtKB/TrEMBL
UniProt	I3M0I0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Send us a Message

Imported Disease Annotations - ClinVar

RGD Manual Annotations