Slc22a7 (solute carrier family 22 member 7)

Gene: Slc22a7 (solute carrier family 22 member 7) Ictidomys tridecemlineatus

Analyze

Symbol:

Slc22a7

Name:

solute carrier family 22 member 7

RGD ID:

12514217

Description:

ENCODES a protein that exhibits organic anion transmembrane transporter activity (ortholog); sodium-independent organic anion transmembrane transporter activity (ortholog); INVOLVED IN organic anion transport (ortholog); response to stilbenoid (ortholog); PARTICIPATES IN multispecific organic anion transporter mediated transport pathway; ASSOCIATED WITH Drug-Related Side Effects and Adverse Reactions (ortholog); infantile Refsum disease (ortholog); Zellweger syndrome (ortholog); FOUND IN apical plasma membrane (inferred); basal plasma membrane (inferred); basolateral plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	47,279,993 - 47,284,825 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	16,675,026 - 16,680,209 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	16,675,377 - 16,680,209 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

infantile Refsum disease (ISO)

Zellweger syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

alpha-ketoglutarate transport (IEA)

organic anion transport (ISO)

organic substance transport (IEA)

prostaglandin transport (IEA)

response to stilbenoid (ISO)

transmembrane transport (IEA)

Cellular Component

apical plasma membrane (IEA)

basal plasma membrane (IEA)

basolateral plasma membrane (IEA)

membrane (IEA)

plasma membrane (IEA)

Molecular Function

alpha-ketoglutarate transmembrane transporter activity (IEA)

organic anion transmembrane transporter activity (IEA,ISO)

prostaglandin transmembrane transporter activity (IEA)

protein binding (ISO)

sodium-independent organic anion transmembrane transporter activity (ISO)

transmembrane transporter activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

multispecific organic anion transporter mediated transport pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Slc22a7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	47,279,993 - 47,284,825 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	16,675,026 - 16,680,209 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	16,675,377 - 16,680,209 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC22A7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	43,295,714 - 43,305,538 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	43,295,694 - 43,305,538 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	43,265,998 - 43,273,276 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	43,373,976 - 43,381,254 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	43,373,979 - 43,381,252	NCBI
Celera	6	44,817,758 - 44,825,036 (+)	NCBI		Celera
Cytogenetic Map	6	p21.1	NCBI
HuRef	6	42,984,503 - 42,991,781 (+)	NCBI		HuRef
CHM1_1	6	43,268,944 - 43,276,222 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	43,127,200 - 43,134,478 (+)	NCBI		T2T-CHM13v2.0

Slc22a7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	46,743,111 - 46,749,403 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	46,743,109 - 46,749,383 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	46,432,185 - 46,438,477 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	46,432,183 - 46,438,457 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	46,569,134 - 46,575,426 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	45,895,372 - 45,901,620 (-)	NCBI		MGSCv36	mm8
Celera	17	49,867,036 - 49,874,196 (-)	NCBI		Celera
Cytogenetic Map	17	C	NCBI
cM Map	17	22.9	NCBI

Slc22a7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	22,044,672 - 22,052,051 (+)	NCBI		GRCr8
mRatBN7.2	9	14,547,073 - 14,554,354 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	14,547,849 - 14,553,921 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	23,131,122 - 23,136,904 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	28,194,555 - 28,200,325 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	26,494,501 - 26,500,283 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	16,925,321 - 16,931,119 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	16,924,520 - 16,931,766 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	15,822,368 - 15,828,166 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	9,934,309 - 9,940,107 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	9,931,570 - 9,937,643 (+)	NCBI
Celera	9	12,295,095 - 12,300,893 (+)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

Slc22a7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	9,204,322 - 9,210,086 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	9,204,414 - 9,210,350 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC22A7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	57,798,445 - 57,805,672 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	53,668,286 - 53,675,511 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	42,888,110 - 42,897,556 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	44,182,287 - 44,189,567 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	44,182,288 - 44,189,097 (+)	Ensembl	panpan1.1		panPan2

SLC22A7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	11,781,623 - 11,788,256 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	11,808,639 - 11,814,376 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	12,265,706 - 12,271,443 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	12	11,791,445 - 11,797,183 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	11,875,644 - 11,881,384 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	11,970,737 - 11,976,476 (+)	NCBI		UU_Cfam_GSD_1.0

SLC22A7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	38,328,419 - 38,334,878 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	38,328,474 - 38,334,879 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	43,828,928 - 43,834,428 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC22A7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	28,848,115 - 28,856,298 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	28,846,791 - 28,855,355 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	43,359,183 - 43,366,555 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc22a7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	16,276,437 - 16,281,741 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624754	16,275,689 - 16,282,141 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013366608	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000027628 ⟹ ENSSTOP00000021367

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936476	16,675,026 - 16,680,200 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000042806 ⟹ ENSSTOP00000031289

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936476	16,675,377 - 16,680,209 (-)	Ensembl

RefSeq Acc Id:

XM_013366608 ⟹ XP_013222062

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	47,279,993 - 47,284,825 (+)	NCBI
SpeTri2.0	NW_004936476	16,675,377 - 16,680,209 (-)	NCBI

Sequence:

show sequence

GTGGGCAGCATGGGCTTTGAGGAACTGCTGGATGAAGTGGGTGGCTTTGGATCCTTCCAACTGC
GGAATCTGGCACTAATGGCCCTGCCCCGAGTGATACTACCCCTGAATTTTCTCCTGCCTATCTT
CCTGGCTGCTGTGCCTGCCCACCACTGTGCCCTGCCTGGCACCCTTGACAACTTCAGTCACCAG
GAGGCATGGCTGGAGACCCATCTGCCCCGGGAGCCCGATGGCAGGTTTAGCTCCTGCCTCCGCT
TTGCTCACCCCCAGACTCTCCCCAACACCACACTGGGGAGAGAGGCACCGAGTCCTGGGGAGCT
GGAAGGAGAACCCTCAACCGTGCCCTGCTCTCAGGGCTGGGAATACGATCGCTCAGAATTCTCC
TCCACCATTGCAACTGAGTGGGATCTGGTATGTGAACGGAAAGGCCTGAACAGAGTTGCATCCA
CCTTGTTCTTCATTGGTGTGCTGATGGGGGCTGTGGTCTTTGGATACCTGTCTGACAGGTTTGG
ACGGCGCCGTCTACTGCTGGTGGCCTATGTGAGTACCCTAGTGCTGGGCCTGACATCTGCAGCC
TCAGTCAACTATGTCATGTTTGCCATCACCCGCACCCTCACTGGCTCAACCCTGGCTGGTTTCA
CCATTATTGTGTTGCCACTTGAGCTGGAGTGGCTGGATGTGGAACACCGTGAAGTGGCCGGCAT
CCTGGGCTCCACCTTCTGGACAGGAGGCGTGCTGCTGCTGGCTTTGGCTGGGTACCTGATAAGG
GACTGGCGATGGCTCCTGATGGCTGTTACTTTGCCTTGTGTCATAGGCATCCTCAGCATACGGT
GGGTGCCTGAATCTGCACGCTGGCTTCTGACTCAGGGCCGAGTGGAGGAGGCCCAAAGGTATTT
GCTCCACTGTGCCAGGCTCAATGGGCGGCCTGTGGGTGAGGACAGCCTGAGCCAGGAGGCCCTG
AACAAAGTGTCCACGGGGGAACAGGTGTTCCCAAGACCCTCCTACCTAGACCTATTCCGAACAC
CACAGATCCGGCACATCTCATTGTGCTGCATGGTGATGTGGTTTTCAGTAAACTTCTCCTATTA
CGGCTTGAGCCTGGACTTGTCGGGGCTGAGGCTGAACGTGTACCAGACGCAGCTGCTGTTCGGG
GCGGTGGAGCTGCCCTCCAAGCTGGTGGTCTATCTGTTGGTGCGCCGTGCGGGGCGCCGGCTCA
CGCAGGCCGGAGCACTGCTGGGCACGGCCTTGACCTTCGGCATCAGATTGCTGGTGTCCTCGGA
GACGAGTTCCTGGAGCACGGCCCTGGCGGTGATAGGGAAAGGTTTCAGTGAAGCCGCCTTCACA
ACTGCCTACCTGTTCACTTCAGAATTGTACCCTACAGTGCTCAGACCAACAGGTATAGGGCTGA
CTTCACTAGTGGGCCGACTGGGGGGCTCTTTGGCCCCACTGGCAGCCTTGCTGGATGGAGTATG
GCTGTCATTGCCCAAGCTTGCTTATGGGGGCATTGCCCTGCTGGCTACCTGCACTACCTTCCTG
CTGCCAGAGACGAGGCAAGCACAGCTGCCAGAGACCATCCAGGATGTGGAGAGAAAGAGGTGTG
TATATAGGACTGTGTATGTGTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013222062	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000021367.2
	ENSSTOP00000031289.1

RefSeq Acc Id:

XP_013222062 ⟸ XM_013366608

- UniProtKB:

A0A287DCM9 (UniProtKB/TrEMBL), I3NAH0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGFEELLDEVGGFGSFQLRNLALMALPRVILPLNFLLPIFLAAVPAHHCALPGTLDNFSHQEAW
LETHLPREPDGRFSSCLRFAHPQTLPNTTLGREAPSPGELEGEPSTVPCSQGWEYDRSEFSSTI
ATEWDLVCERKGLNRVASTLFFIGVLMGAVVFGYLSDRFGRRRLLLVAYVSTLVLGLTSAASVN
YVMFAITRTLTGSTLAGFTIIVLPLELEWLDVEHREVAGILGSTFWTGGVLLLALAGYLIRDWR
WLLMAVTLPCVIGILSIRWVPESARWLLTQGRVEEAQRYLLHCARLNGRPVGEDSLSQEALNKV
STGEQVFPRPSYLDLFRTPQIRHISLCCMVMWFSVNFSYYGLSLDLSGLRLNVYQTQLLFGAVE
LPSKLVVYLLVRRAGRRLTQAGALLGTALTFGIRLLVSSETSSWSTALAVIGKGFSEAAFTTAY
LFTSELYPTVLRPTGIGLTSLVGRLGGSLAPLAALLDGVWLSLPKLAYGGIALLATCTTFLLPE
TRQAQLPETIQDVERKRCVYRTVYV

hide sequence

RefSeq Acc Id:

ENSSTOP00000021367 ⟸ ENSSTOT00000027628

RefSeq Acc Id:

ENSSTOP00000031289 ⟸ ENSSTOT00000042806

Protein Domains

Major facilitator superfamily (MFS) profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000024272	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000027628.2	UniProtKB/TrEMBL
	ENSSTOT00000042806.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1250.20	UniProtKB/TrEMBL
InterPro	MFS	UniProtKB/TrEMBL
	MFS_dom	UniProtKB/TrEMBL
	MFS_trans_sf	UniProtKB/TrEMBL
	Orgcat_transp/SVOP	UniProtKB/TrEMBL
NCBI Gene	Slc22a7	ENTREZGENE
PANTHER	SOLUTE CARRIER FAMILY 22 MEMBER	UniProtKB/TrEMBL
	SOLUTE CARRIER FAMILY 22 MEMBER 7	UniProtKB/TrEMBL
Pfam	MFS_1	UniProtKB/TrEMBL
PROSITE	MFS	UniProtKB/TrEMBL
Superfamily-SCOP	SSF103473	UniProtKB/TrEMBL
UniProt	A0A287DCM9	ENTREZGENE, UniProtKB/TrEMBL
	I3NAH0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

RGD Manual Annotations