Garnl3 (GTPase activating Rap/RanGAP domain like 3) - Rat Genome Database

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Gene: Garnl3 (GTPase activating Rap/RanGAP domain like 3) Ictidomys tridecemlineatus
Analyze
Symbol: Garnl3
Name: GTPase activating Rap/RanGAP domain like 3
RGD ID: 12474748
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of small GTPase mediated signal transduction (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy (ortholog); developmental and epileptic encephalopathy 31A (ortholog); early infantile epileptic encephalopathy (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GTPase activating Rap/RanGAP domain like 3, transcript variant X1; GTPase activating Rap/RanGAP domain like 3, transcript variant X2; GTPase activating Rap/RanGAP domain like 3, transcript variant X3; GTPase activating Rap/RanGAP domain like 3, transcript variant X4; GTPase activating Rap/RanGAP domain like 3, transcript variant X5; GTPase activating Rap/RanGAP domain like 3, transcript variant X6; GTPase-activating Rap/Ran-GAP domain-like protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,237,098 - 195,384,304 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,005,575 - 15,152,953 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,017,587 - 15,151,647 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Garnl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,237,098 - 195,384,304 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,005,575 - 15,152,953 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,017,587 - 15,151,647 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GARNL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,224,613 - 127,393,660 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9127,224,265 - 127,393,660 (+)EnsemblGRCh38hg38GRCh38
GRCh379130,026,178 - 130,155,939 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,066,967 - 129,195,649 (+)NCBINCBI36Build 36hg18NCBI36
Build 349127,106,699 - 127,235,380NCBI
Celera9100,681,389 - 100,810,468 (+)NCBICelera
Cytogenetic Map9q33.3NCBI
HuRef999,642,408 - 99,771,209 (+)NCBIHuRef
CHM1_19130,177,442 - 130,306,494 (+)NCBICHM1_1
T2T-CHM13v2.09139,431,005 - 139,600,139 (+)NCBIT2T-CHM13v2.0
Garnl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,876,237 - 33,021,871 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,876,236 - 33,021,666 (-)EnsemblGRCm39 Ensembl
GRCm38232,986,225 - 33,131,859 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,986,224 - 33,131,654 (-)EnsemblGRCm38mm10GRCm38
MGSCv37232,841,886 - 32,942,724 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,808,375 - 32,909,213 (-)NCBIMGSCv36mm8
Celera232,693,353 - 32,794,303 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Garnl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,686,388 - 36,830,011 (-)NCBIGRCr8
mRatBN7.2316,288,718 - 16,432,308 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl316,288,719 - 16,430,837 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0312,034,131 - 12,176,591 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl312,034,413 - 12,155,098 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0317,370,764 - 17,464,230 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,976,369 - 12,076,318 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera311,027,567 - 11,168,914 (-)NCBICelera
Cytogenetic Map3p11NCBI
Garnl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554191,190,344 - 1,332,553 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554191,190,059 - 1,332,553 (-)NCBIChiLan1.0ChiLan1.0
GARNL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,960,249 - 12,130,724 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,962,596 - 12,133,074 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,343,954 - 98,514,381 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19126,998,418 - 127,168,056 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,038,457 - 127,168,056 (+)Ensemblpanpan1.1panPan2
GARNL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,931,995 - 56,078,521 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,932,016 - 56,078,391 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha955,135,764 - 55,282,398 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,853,507 - 57,000,577 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,853,514 - 57,000,891 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1955,613,247 - 55,760,021 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,928,572 - 56,075,173 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0956,019,498 - 56,166,262 (-)NCBIUU_Cfam_GSD_1.0
GARNL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1267,772,347 - 267,923,390 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11267,772,408 - 267,922,731 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21301,693,696 - 301,833,904 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GARNL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,734,969 - 10,911,786 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,734,798 - 10,911,816 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660795,305,259 - 5,480,301 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Garnl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247608,069,606 - 8,235,443 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247608,069,321 - 8,235,409 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000005360   ⟹   ENSSTOP00000004802
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648715,036,411 - 15,151,351 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000037023   ⟹   ENSSTOP00000028152
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648715,005,575 - 15,152,953 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000038156   ⟹   ENSSTOP00000032674
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648715,017,606 - 15,152,953 (+)Ensembl
RefSeq Acc Id: XM_005320982   ⟹   XP_005321039
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947195,249,735 - 195,383,407 (+)NCBI
SpeTri2.0NW_00493648715,017,587 - 15,151,647 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723559   ⟹   XP_021579234
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947195,237,098 - 195,384,304 (+)NCBI
SpeTri2.0NW_00493648715,017,587 - 15,151,637 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723560   ⟹   XP_021579235
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947195,249,735 - 195,383,407 (+)NCBI
SpeTri2.0NW_00493648715,017,587 - 15,151,647 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723561   ⟹   XP_021579236
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947195,249,735 - 195,383,407 (+)NCBI
SpeTri2.0NW_00493648715,017,587 - 15,151,637 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723562   ⟹   XP_021579237
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947195,249,735 - 195,366,658 (+)NCBI
SpeTri2.0NW_00493648715,017,587 - 15,135,065 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723563   ⟹   XP_021579238
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947195,249,771 - 195,383,407 (+)NCBI
SpeTri2.0NW_00493648715,018,349 - 15,151,647 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040286340   ⟹   XP_040142274
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947195,268,592 - 195,384,304 (+)NCBI
RefSeq Acc Id: XM_040286341   ⟹   XP_040142275
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947195,267,734 - 195,384,304 (+)NCBI
RefSeq Acc Id: XM_040286342   ⟹   XP_040142276
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947195,267,559 - 195,384,304 (+)NCBI
RefSeq Acc Id: XM_040286343   ⟹   XP_040142277
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947195,268,549 - 195,384,304 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005321039   ⟸   XM_005320982
- Peptide Label: isoform X5
- UniProtKB: A0A287D3Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021579235   ⟸   XM_021723560
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021579234   ⟸   XM_021723559
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021579236   ⟸   XM_021723561
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_021579237   ⟸   XM_021723562
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_021579238   ⟸   XM_021723563
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_040142276   ⟸   XM_040286342
- Peptide Label: isoform X7
- UniProtKB: I3M5X9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040142275   ⟸   XM_040286341
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040142277   ⟸   XM_040286343
- Peptide Label: isoform X9
RefSeq Acc Id: XP_040142274   ⟸   XM_040286340
- Peptide Label: isoform X4
RefSeq Acc Id: ENSSTOP00000028152   ⟸   ENSSTOT00000037023
RefSeq Acc Id: ENSSTOP00000032674   ⟸   ENSSTOT00000038156
RefSeq Acc Id: ENSSTOP00000004802   ⟸   ENSSTOT00000005360
Protein Domains
CNH   Rap-GAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000005340 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000005360.3 UniProtKB/TrEMBL
  ENSSTOT00000037023.1 UniProtKB/TrEMBL
  ENSSTOT00000038156.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.11210 UniProtKB/TrEMBL
InterPro CNH_dom UniProtKB/TrEMBL
  Rap/Ran-GAP_sf UniProtKB/TrEMBL
  Rap/Ran_GAP_dom UniProtKB/TrEMBL
NCBI Gene Garnl3 ENTREZGENE
PANTHER GTPASE-ACTIVATING RAP/RAN-GAP DOMAIN-LIKE PROTEIN 3 UniProtKB/TrEMBL
  RAP GTPASE-ACTIVATING PROTEIN UniProtKB/TrEMBL
Pfam CNH UniProtKB/TrEMBL
  Rap_GAP UniProtKB/TrEMBL
PROSITE CNH UniProtKB/TrEMBL
  RAPGAP UniProtKB/TrEMBL
Superfamily-SCOP SSF111347 UniProtKB/TrEMBL
UniProt A0A287D3Q4 ENTREZGENE, UniProtKB/TrEMBL
  I3M5X9 ENTREZGENE, UniProtKB/TrEMBL