Rab8b (RAB8B, member RAS oncogene family) - Rat Genome Database

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Gene: Rab8b (RAB8B, member RAS oncogene family) Ictidomys tridecemlineatus
Analyze
Symbol: Rab8b
Name: RAB8B, member RAS oncogene family
RGD ID: 12463439
Description: ENCODES a protein that exhibits TPR domain binding (ortholog); INVOLVED IN cell-substrate junction organization (ortholog); cilium assembly (ortholog); positive regulation of cell projection organization (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cell tip (ortholog); perinuclear region of cytoplasm (ortholog); presynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rab-8B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640105,920,372 - 105,983,602 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647123,768,415 - 23,834,129 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647123,768,460 - 23,832,072 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rab8b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640105,920,372 - 105,983,602 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647123,768,415 - 23,834,129 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647123,768,460 - 23,832,072 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB8B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381563,189,606 - 63,267,776 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1563,189,560 - 63,267,776 (+)EnsemblGRCh38hg38GRCh38
GRCh371563,481,805 - 63,559,975 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361561,268,781 - 61,347,028 (+)NCBINCBI36Build 36hg18NCBI36
Build 341561,268,785 - 61,343,422NCBI
Celera1540,361,335 - 40,438,724 (+)NCBICelera
Cytogenetic Map15q22.2NCBI
HuRef1540,304,775 - 40,382,999 (+)NCBIHuRef
CHM1_11563,600,874 - 63,679,075 (+)NCBICHM1_1
T2T-CHM13v2.01560,994,386 - 61,072,552 (+)NCBIT2T-CHM13v2.0
Rab8b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39966,750,891 - 66,826,987 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl966,750,946 - 66,826,969 (-)EnsemblGRCm39 Ensembl
GRCm38966,843,609 - 66,919,705 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl966,843,664 - 66,919,687 (-)EnsemblGRCm38mm10GRCm38
MGSCv37966,691,471 - 66,767,512 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36966,642,808 - 66,718,831 (-)NCBIMGSCv36mm8
Celera964,077,884 - 64,154,033 (-)NCBICelera
Cytogenetic Map9CNCBI
cM Map936.17NCBI
Rab8b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8876,340,106 - 76,417,638 (-)NCBIGRCr8
mRatBN7.2867,458,921 - 67,536,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl867,458,923 - 67,536,384 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx872,992,995 - 73,067,789 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0871,265,830 - 71,340,724 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0869,100,711 - 69,178,108 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0872,641,680 - 72,714,646 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl872,638,003 - 72,714,664 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0876,975,899 - 77,047,482 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4871,156,502 - 71,231,807 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1871,175,555 - 71,250,861 (-)NCBI
Celera874,168,077 - 74,238,512 (+)NCBICelera
Cytogenetic Map8q24NCBI
Rab8b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545012,026,784 - 12,095,422 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545012,026,784 - 12,095,332 (-)NCBIChiLan1.0ChiLan1.0
RAB8B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21652,438,265 - 52,516,306 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11556,614,260 - 56,692,351 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01542,136,776 - 42,214,792 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11560,432,749 - 60,510,547 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1560,432,749 - 60,510,547 (+)Ensemblpanpan1.1panPan2
RAB8B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13027,784,298 - 27,845,901 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3027,784,387 - 27,842,065 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3027,703,275 - 27,764,927 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03027,955,859 - 28,017,574 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3027,955,891 - 28,017,579 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13027,893,427 - 27,955,069 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03027,955,252 - 28,016,926 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03028,198,967 - 28,260,665 (+)NCBIUU_Cfam_GSD_1.0
RAB8B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1108,772,851 - 108,840,227 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11108,772,851 - 108,840,222 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21119,998,446 - 120,063,398 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAB8B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12620,275,555 - 20,354,298 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2620,275,258 - 20,354,202 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048121,045,683 - 121,125,449 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab8b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247819,251,212 - 9,325,642 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247819,253,039 - 9,324,873 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005316658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010003700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000016047   ⟹   ENSSTOP00000014361
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647123,768,415 - 23,834,129 (+)Ensembl
RefSeq Acc Id: XM_005316658   ⟹   XP_005316715
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640105,920,372 - 105,983,602 (+)NCBI
SpeTri2.0NW_00493647123,768,460 - 23,832,072 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005316715 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000014361.2
GenBank Protein KAG3262008 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005316715   ⟸   XM_005316658
- UniProtKB: I3MQU0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000014361   ⟸   ENSSTOT00000016047


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000016046 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000016047.3 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
NCBI Gene Rab8b ENTREZGENE
PANTHER LD44762P UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-8B UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART ARF UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt I3MQU0 ENTREZGENE, UniProtKB/TrEMBL