Sash1 (SAM and SH3 domain containing 1) - Rat Genome Database

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Gene: Sash1 (SAM and SH3 domain containing 1) Ictidomys tridecemlineatus
Analyze
Symbol: Sash1
Name: SAM and SH3 domain containing 1
RGD ID: 12443205
Description: ENCODES a protein that exhibits G-protein alpha-subunit binding (inferred); mitogen-activated protein kinase kinase kinase binding (inferred); molecular adaptor activity (inferred); INVOLVED IN positive regulation of angiogenesis (ortholog); positive regulation of endothelial cell migration (ortholog); positive regulation of lipopolysaccharide-mediated signaling pathway (ortholog); ASSOCIATED WITH Cancer, Alopecia, Pigment Dyscrasia, Onychodystrophy, and Keratoderma (ortholog); Dyschromatosis Universalis Hereditaria 1 (ortholog); genetic disease (ortholog); FOUND IN membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SAM and SH3 domain containing 1, transcript variant X1; SAM and SH3 domain containing 1, transcript variant X2; SAM and SH3 domain containing 1, transcript variant X3; SAM and SH3 domain containing 1, transcript variant X4; SAM and SH3 domain containing 1, transcript variant X5; SAM and SH3 domain containing 1, transcript variant X6; SAM and SH3 domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946134,317,060 - 134,488,406 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364891,447,885 - 1,740,400 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364891,569,143 - 1,740,398 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Sash1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946134,317,060 - 134,488,406 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364891,447,885 - 1,740,400 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364891,569,143 - 1,740,398 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SASH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386148,193,468 - 148,552,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6148,272,304 - 148,552,044 (+)EnsemblGRCh38hg38GRCh38
GRCh376148,593,464 - 148,873,180 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366148,705,422 - 148,914,877 (+)NCBINCBI36Build 36hg18NCBI36
Build 346148,705,421 - 148,914,877NCBI
Celera6149,404,636 - 149,614,083 (+)NCBICelera
Cytogenetic Map6q24.3-q25.1NCBI
HuRef6146,228,564 - 146,437,707 (+)NCBIHuRef
CHM1_16148,927,589 - 149,138,096 (+)NCBICHM1_1
T2T-CHM13v2.06149,389,474 - 149,748,326 (+)NCBIT2T-CHM13v2.0
Sash1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39108,597,981 - 8,821,290 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl108,597,983 - 8,761,814 (-)EnsemblGRCm39 Ensembl
GRCm38108,722,217 - 8,945,608 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl108,722,219 - 8,886,070 (-)EnsemblGRCm38mm10GRCm38
MGSCv37108,442,017 - 8,605,868 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36108,412,409 - 8,576,075 (-)NCBIMGSCv36mm8
Celera108,606,870 - 8,773,158 (-)NCBICelera
Cytogenetic Map10A1NCBI
cM Map102.75NCBI
Sash1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814,940,207 - 5,238,777 (-)NCBIGRCr8
mRatBN7.213,119,915 - 3,418,536 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13,121,332 - 3,439,870 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.012,782,905 - 2,950,749 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl12,782,864 - 2,846,200 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014,467,643 - 4,632,109 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413,322,905 - 3,486,748 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera11,666,679 - 1,982,045 (-)NCBICelera
Cytogenetic Map1p13NCBI
Sash1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543912,550,273 - 12,839,896 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543912,551,361 - 12,729,500 (-)NCBIChiLan1.0ChiLan1.0
SASH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25168,287,588 - 168,574,591 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16166,254,686 - 166,468,553 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06146,154,178 - 146,368,101 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16150,863,677 - 151,075,817 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6150,863,677 - 151,075,816 (+)Ensemblpanpan1.1panPan2
SASH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1139,221,243 - 39,478,057 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl139,146,020 - 39,476,914 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha140,063,060 - 40,376,699 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0139,338,888 - 39,653,867 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl139,321,449 - 39,651,475 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1139,334,532 - 39,530,859 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0139,083,215 - 39,397,497 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0139,422,669 - 39,737,198 (+)NCBIUU_Cfam_GSD_1.0
SASH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl117,306,373 - 17,511,672 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1117,306,364 - 17,663,117 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SASH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11323,147,162 - 24,240,008 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1323,147,160 - 23,369,118 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040199,128,646 - 199,411,956 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sash1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247859,553,982 - 9,854,034 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247859,555,146 - 9,795,638 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000002372   ⟹   ENSSTOP00000002122
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364891,569,537 - 1,737,329 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000031964   ⟹   ENSSTOP00000031837
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364891,569,082 - 1,740,400 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000034801   ⟹   ENSSTOP00000024604
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364891,447,885 - 1,740,400 (+)Ensembl
RefSeq Acc Id: XM_005321353   ⟹   XP_005321410
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946134,317,065 - 134,488,406 (+)NCBI
SpeTri2.0NW_0049364891,569,156 - 1,740,398 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013356911   ⟹   XP_013212365
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946134,450,134 - 134,488,406 (+)NCBI
SpeTri2.0NW_0049364891,702,051 - 1,740,398 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723893   ⟹   XP_021579568
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946134,317,060 - 134,488,406 (+)NCBI
SpeTri2.0NW_0049364891,569,143 - 1,740,398 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723895   ⟹   XP_021579570
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946134,450,126 - 134,488,406 (+)NCBI
SpeTri2.0NW_0049364891,702,043 - 1,740,398 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723896   ⟹   XP_021579571
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946134,454,879 - 134,488,406 (+)NCBI
SpeTri2.0NW_0049364891,706,439 - 1,740,398 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005321410   ⟸   XM_005321353
- Peptide Label: isoform X2
- UniProtKB: A0A287DE59 (UniProtKB/TrEMBL),   I3M0A4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013212365   ⟸   XM_013356911
- Peptide Label: isoform X5
- UniProtKB: A0A287CTK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021579568   ⟸   XM_021723893
- Peptide Label: isoform X1
- UniProtKB: I3M0A4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021579570   ⟸   XM_021723895
- Peptide Label: isoform X3
- UniProtKB: A0A287CTK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021579571   ⟸   XM_021723896
- Peptide Label: isoform X4
- UniProtKB: A0A287CTK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000031837   ⟸   ENSSTOT00000031964
RefSeq Acc Id: ENSSTOP00000024604   ⟸   ENSSTOT00000034801
RefSeq Acc Id: ENSSTOP00000002122   ⟸   ENSSTOT00000002372
Protein Domains
SAM   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002365 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000002372.3 UniProtKB/TrEMBL
  ENSSTOT00000031964.1 UniProtKB/TrEMBL
  ENSSTOT00000034801.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro rSAM/SH3_domain-containing UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  SASH1_SAM_repeat1 UniProtKB/TrEMBL
  SASH1_SAM_repeat2 UniProtKB/TrEMBL
  SASH1_SH3 UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene Sash1 ENTREZGENE
PANTHER SAM AND SH3 DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED UniProtKB/TrEMBL
Pfam SAM_1 UniProtKB/TrEMBL
  SAM_2 UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
  SLY UniProtKB/TrEMBL
PROSITE SAM_DOMAIN UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART SAM UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A287CTK5 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DE59 ENTREZGENE, UniProtKB/TrEMBL
  I3M0A4 ENTREZGENE, UniProtKB/TrEMBL