BROX (BRO1 domain and CAAX motif containing)

Gene: BROX (BRO1 domain and CAAX motif containing) Canis lupus familiaris

Analyze

Symbol:

BROX

Name:

BRO1 domain and CAAX motif containing

RGD ID:

12409137

Description:

INVOLVED IN mitotic nuclear membrane reassembly (inferred); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); Loeys-Dietz syndrome 4 (ortholog); parathyroid carcinoma (ortholog); FOUND IN nuclear envelope (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

BRO1 domain-containing protein BROX

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	16,971,449 - 16,990,673 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	16,971,504 - 16,990,372 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	17,027,790 - 17,047,007 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	17,017,951 - 17,039,102 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	17,017,765 - 17,040,508 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	17,023,182 - 17,044,114 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	17,372,045 - 17,391,207 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	17,667,450 - 17,688,535 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

gastrointestinal stromal tumor (ISO)

Loeys-Dietz syndrome 4 (ISO)

parathyroid carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mitotic nuclear membrane reassembly (IEA)

Cellular Component

nuclear envelope (IEA)

Molecular Function

protein binding (ISO)

References

Genomics

Comparative Map Data

BROX
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	16,971,449 - 16,990,673 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	16,971,504 - 16,990,372 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	17,027,790 - 17,047,007 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	17,017,951 - 17,039,102 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	17,017,765 - 17,040,508 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	17,023,182 - 17,044,114 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	17,372,045 - 17,391,207 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	17,667,450 - 17,688,535 (+)	NCBI		UU_Cfam_GSD_1.0

BROX
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	222,712,564 - 222,735,187 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	222,712,553 - 222,735,196 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	222,885,906 - 222,908,529 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	220,952,529 - 220,972,732 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	196,105,074 - 196,125,277 (+)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI
HuRef	1	193,560,289 - 193,580,492 (+)	NCBI		HuRef
CHM1_1	1	224,158,972 - 224,179,175 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	221,946,320 - 221,968,943 (+)	NCBI		T2T-CHM13v2.0

Brox
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	183,057,916 - 183,078,839 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	183,057,916 - 183,078,813 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	183,276,352 - 183,297,298 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	183,276,352 - 183,297,269 (-)	Ensembl	GRCm38		mm10	GRCm38
Celera	1	190,277,448 - 190,298,022 (-)	NCBI		Celera
Cytogenetic Map	1	H5	NCBI

Brox
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	97,451,736 - 97,471,598 (-)	NCBI		GRCr8
mRatBN7.2	13	94,920,107 - 94,940,189 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	94,920,112 - 94,940,227 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	97,425,477 - 97,445,264 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	98,825,287 - 98,845,074 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	96,007,437 - 96,027,220 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	101,677,896 - 101,697,743 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	101,677,902 - 101,697,684 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	100,886,368 - 100,906,452 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	99,319,507 - 99,339,291 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	99,508,442 - 99,528,227 (-)	NCBI
Celera	13	94,447,203 - 94,466,862 (-)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

Brox
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955520	1,797,657 - 1,818,708 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955520	1,797,657 - 1,819,359 (-)	NCBI	ChiLan1.0	ChiLan1.0

BROX
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	26,586,043 - 26,608,455 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	26,539,467 - 26,561,876 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	198,385,748 - 198,408,408 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	203,399,224 - 203,421,920 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	203,399,224 - 203,421,920 (+)	Ensembl	panpan1.1		panPan2

Brox
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	54,717,189 - 54,741,113 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	6,496 - 30,743 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	6,185 - 30,108 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BROX
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	11,466,004 - 11,486,974 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	11,466,173 - 11,486,983 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	13,621,400 - 13,636,473 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BROX
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	6,835,448 - 6,858,097 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	6,834,584 - 6,858,052 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	7,073,830 - 7,096,754 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Brox
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624835	5,240,333 - 5,261,416 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624835	5,240,643 - 5,261,299 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in BROX
305 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5	22	6	6	6	6	5	12	8	10	6
Low								1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005640838	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005640839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038448500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038448501	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038448502	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038522406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038522407	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038522408	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038586205	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038586206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038586207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038650612	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038650613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038650614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_536151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000021449 ⟹ ENSCAFP00000019917

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	38	16,971,504 - 16,990,372 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000075979 ⟹ ENSCAFP00000063984

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	38	16,971,504 - 16,989,810 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000081000 ⟹ ENSCAFP00000043541

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	38	16,971,504 - 16,990,372 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845054164 ⟹ ENSCAFP00845042557

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	38	17,017,765 - 17,040,508 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845054180 ⟹ ENSCAFP00845042569

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	38	17,017,765 - 17,036,454 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845054190 ⟹ ENSCAFP00845042574

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	38	17,017,996 - 17,039,084 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845054210 ⟹ ENSCAFP00845042589

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	38	17,017,996 - 17,039,084 (+)	Ensembl

RefSeq Acc Id:

XM_005640838 ⟹ XP_005640895

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	38	16,971,919 - 16,990,673 (+)	NCBI
Dog10K_Boxer_Tasha	38	17,028,271 - 17,047,007 (+)	NCBI

Sequence:

show sequence

GCTTTCCACGAAAATGCCTGGTGGGAGCAGAGGCGCCGAGGCTTGGCGCCTGCGCAGTATCGCC
GCGCGCCGCCCCCGGGGGTCGGGGCTCGGCCGGAAGAGGCGGGGGATAAACCGGAAGTGGGCGC
TCGGAGCTCGGGGGTGGCGCTCAGGAGACAGCTGGAGAAAATGACACATTGGTTTCATAGGAAC
CCATTAAAAGCCACAGCTCCCGTTGCTTTTAACTACTATGGTGTAGCTGCTGGTCCTGCCGCTT
CAAAAATTTGCAGTGACTTGAGATCATCCAGAGCACGACTGCTCGAACTCTTCACTGATTTGAG
CTGTAATCCAGAAATGATGAAGAATGCAGCAGATTCCTATTTTTCACTTTTACAAGGTTTCATA
AATTCATTGGATGAATCTACCCAAGAGAGCAAGTTACGATATATTCAAAATTTCAAGTGGACTG
ATACATTACAAGGACAGGTTCCAAGTGCCCAGCAGGATGCTGTTTTTGAATTAATTTCCATGGG
ATTTAATGTAGCTTTATGGTATACCAAATATGCTTCAAGACTGGCTGGAAAAGAAAACATAACA
GAAGATGAAGCAAAAGAAGTCCATCGAAGCCTAAAAATTGCAGCGGGGATTTTTAAACATTTAA
AGGAAAGTCAGATCCCAAAGCTTATTACACCTGCAGAAAAGGGGAGGGACTTAGAGGCACGACT
TCTAGAAGCTTATGTTGTCCAGTGTCAGGCTGAAGCTCAAGAAGTAACAATTGCTCGAGCCATT
GAACTGAAACATGCTCCTGGGCTTATTGCTGCCCTGGCATATGAAACTGCCAACTTCTATCAAA
AAGCTGATCATACTTTATCCAGTTTGGAGCCTGCTTATTCTGCTAAATGGAGAAAATATCTTCA
CTTGAAAATGTGTTTCTACACAGCTTATGCTTACTGTTATCATGGTCAAACTTTGTTGGCTAGT
GATAAATGTGGTGAAGCAATCAGGTCTCTCCAAGAAGCAGAAAAATTTTATGCAAAGGCAGAAG
CATTGTGCAAAGAATATGGAGAAACCAAAGGACCTGGGCCAACAGTCAAACCTTCAGGACACTT
ATTCTTTAGGAGACTTGGAAATCTTGTGAAGAATACCCTCGAGAAATGTCAGAGAGAAAATGGA
TTTATTTACTTTCAAAAAATTCCAACAGAAGCCCCACAGCTGGAACTCAAAGCAAATTATGGTC
TCGTAGAGCCAGTACCTTTTGAATTTCCTCCTACAAGTGCATACTGGACACCAGACACACTGGC
TGCATTTGATCTCACCAAAAGACCCAAGGATGACAGTACCAAATCCAAACCAGAAGAAACGGTG
AAACCTGTGAAAGAGCCAGATATCAAACCTCAGAAGGACACAGGGTGCTCCATCTCCTAAAGTA
CATTGATAAAATGTGCACTTTGAATTTCTCTACTAGTGGATGAGATAAACCGTGGAAGTTCAGT
TCCTATTTCTTGAAGTGTTTTGTCTGAAGCCTGTAGAATGATTTAGTACATTCAGAGGGAATCT
GCCTTCAGTTTATTTGTTCTTGATTTTTAATATAGTAGAGATGTCTCATGCTTTGTTTCCAGAC
TCCTTTTCAATCAGGACAACATGTAAGGATTTTATTGTGCATATTAGGTTGAAGGGCATATTAG
GTTGTTGGTTTTTGTCTCCGAACTCTGGGTAGAAATAAGTTTTGGTTAATGTATTACAGGCCAG
AATCATGTGGTTTCAGGTATCTTTTTCTGTCTTCACACACAAAAGTTTATCATCTTTTGACACC
AGAAGAATGACAGGAGTTGGTTTTTCAGAGTTTTTCCCCCCTCACCATTATGTTGTCTCACAGA
CTTGTTATGTTCTGAGTCCATTATCTTTTCTGGTGGGAAAATCATTTACAGTTAAGGATCAGAA
AATCTTCATACCAAATTCCTTACATATGTAAGAAGCTATAATTTGTTCCAGTATCACTGTTCAT
AGGTATTTTGAGGCCATTTAGGAACTTACTCCAGGGGTGCCTGGCTGGTTCAGTGGGAGGGAGC
ATGTGACTCTTGATCGTGGGGTTCTGAGTTCAAGCGCCATGTTGGACATAGAGGTAACGTAGAT
AAATAAATGAATCTTAAAAAAAAAAAAAATACTCCTCTTCTGGTAGCCCTGCACTTTATTTCAG
TCTCAATAAACATATAGTGATTTTTACAGCTA

hide sequence

RefSeq Acc Id:

XM_005640839 ⟹ XP_005640896

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	38	16,972,866 - 16,990,673 (+)	NCBI
Dog10K_Boxer_Tasha	38	17,029,209 - 17,047,007 (+)	NCBI

Sequence:

show sequence

AAGTGCATCAACAACATTGTATGATGCCTTTAAGTAAATTAAACCTTATCAGGATTTCTTGTCT
CCGACTTCCCGGAATCTACTGGCCACATTTACATGTTCTGCTAGACCTTCCTGTGTTTGCATTA
TCTACCCAAGGACTTGGAGGAGACAGCTGGAGAAAATGACACATTGGTTTCATAGGAACCCATT
AAAAGCCACAGCTCCCGTTGCTTTTAACTACTATGGTGTAGCTGCTGGTCCTGCCGCTTCAAAA
ATTTGCAGTGACTTGAGATCATCCAGAGCACGACTGCTCGAACTCTTCACTGATTTGAGCTGTA
ATCCAGAAATGATGAAGAATGCAGCAGATTCCTATTTTTCACTTTTACAAGGTTTCATAAATTC
ATTGGATGAATCTACCCAAGAGAGCAAGTTACGATATATTCAAAATTTCAAGTGGACTGATACA
TTACAAGGACAGGTTCCAAGTGCCCAGCAGGATGCTGTTTTTGAATTAATTTCCATGGGATTTA
ATGTAGCTTTATGGTATACCAAATATGCTTCAAGACTGGCTGGAAAAGAAAACATAACAGAAGA
TGAAGCAAAAGAAGTCCATCGAAGCCTAAAAATTGCAGCGGGGATTTTTAAACATTTAAAGGAA
AGTCAGATCCCAAAGCTTATTACACCTGCAGAAAAGGGGAGGGACTTAGAGGCACGACTTCTAG
AAGCTTATGTTGTCCAGTGTCAGGCTGAAGCTCAAGAAGTAACAATTGCTCGAGCCATTGAACT
GAAACATGCTCCTGGGCTTATTGCTGCCCTGGCATATGAAACTGCCAACTTCTATCAAAAAGCT
GATCATACTTTATCCAGTTTGGAGCCTGCTTATTCTGCTAAATGGAGAAAATATCTTCACTTGA
AAATGTGTTTCTACACAGCTTATGCTTACTGTTATCATGGTCAAACTTTGTTGGCTAGTGATAA
ATGTGGTGAAGCAATCAGGTCTCTCCAAGAAGCAGAAAAATTTTATGCAAAGGCAGAAGCATTG
TGCAAAGAATATGGAGAAACCAAAGGACCTGGGCCAACAGTCAAACCTTCAGGACACTTATTCT
TTAGGAGACTTGGAAATCTTGTGAAGAATACCCTCGAGAAATGTCAGAGAGAAAATGGATTTAT
TTACTTTCAAAAAATTCCAACAGAAGCCCCACAGCTGGAACTCAAAGCAAATTATGGTCTCGTA
GAGCCAGTACCTTTTGAATTTCCTCCTACAAGTGCATACTGGACACCAGACACACTGGCTGCAT
TTGATCTCACCAAAAGACCCAAGGATGACAGTACCAAATCCAAACCAGAAGAAACGGTGAAACC
TGTGAAAGAGCCAGATATCAAACCTCAGAAGGACACAGGGTGCTCCATCTCCTAAAGTACATTG
ATAAAATGTGCACTTTGAATTTCTCTACTAGTGGATGAGATAAACCGTGGAAGTTCAGTTCCTA
TTTCTTGAAGTGTTTTGTCTGAAGCCTGTAGAATGATTTAGTACATTCAGAGGGAATCTGCCTT
CAGTTTATTTGTTCTTGATTTTTAATATAGTAGAGATGTCTCATGCTTTGTTTCCAGACTCCTT
TTCAATCAGGACAACATGTAAGGATTTTATTGTGCATATTAGGTTGAAGGGCATATTAGGTTGT
TGGTTTTTGTCTCCGAACTCTGGGTAGAAATAAGTTTTGGTTAATGTATTACAGGCCAGAATCA
TGTGGTTTCAGGTATCTTTTTCTGTCTTCACACACAAAAGTTTATCATCTTTTGACACCAGAAG
AATGACAGGAGTTGGTTTTTCAGAGTTTTTCCCCCCTCACCATTATGTTGTCTCACAGACTTGT
TATGTTCTGAGTCCATTATCTTTTCTGGTGGGAAAATCATTTACAGTTAAGGATCAGAAAATCT
TCATACCAAATTCCTTACATATGTAAGAAGCTATAATTTGTTCCAGTATCACTGTTCATAGGTA
TTTTGAGGCCATTTAGGAACTTACTCCAGGGGTGCCTGGCTGGTTCAGTGGGAGGGAGCATGTG
ACTCTTGATCGTGGGGTTCTGAGTTCAAGCGCCATGTTGGACATAGAGGTAACGTAGATAAATA
AATGAATCTTAAAAAAAAAAAAAATACTCCTCTTCTGGTAGCCCTGCACTTTATTTCAGTCTCA
ATAAACATATAGTGATTTTTACAGCTA

hide sequence

RefSeq Acc Id:

XM_038448500 ⟹ XP_038304428

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	38	17,018,432 - 17,039,102 (+)	NCBI

RefSeq Acc Id:

XM_038448501 ⟹ XP_038304429

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	38	17,017,951 - 17,039,102 (+)	NCBI

RefSeq Acc Id:

XM_038448502 ⟹ XP_038304430

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	38	17,019,376 - 17,039,102 (+)	NCBI

RefSeq Acc Id:

XM_038522406 ⟹ XP_038378334

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	38	17,023,182 - 17,044,114 (+)	NCBI

RefSeq Acc Id:

XM_038522407 ⟹ XP_038378335

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	38	17,023,670 - 17,044,114 (+)	NCBI

RefSeq Acc Id:

XM_038522408 ⟹ XP_038378336

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	38	17,024,601 - 17,044,114 (+)	NCBI

RefSeq Acc Id:

XM_038586205 ⟹ XP_038442133

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	38	17,667,931 - 17,688,535 (+)	NCBI

RefSeq Acc Id:

XM_038586206 ⟹ XP_038442134

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	38	17,667,450 - 17,688,535 (+)	NCBI

RefSeq Acc Id:

XM_038586207 ⟹ XP_038442135

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	38	17,668,859 - 17,688,535 (+)	NCBI

RefSeq Acc Id:

XM_038650612 ⟹ XP_038506540

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	38	17,372,526 - 17,391,207 (+)	NCBI

RefSeq Acc Id:

XM_038650613 ⟹ XP_038506541

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	38	17,372,045 - 17,391,207 (+)	NCBI

RefSeq Acc Id:

XM_038650614 ⟹ XP_038506542

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	38	17,373,458 - 17,391,207 (+)	NCBI

RefSeq Acc Id:

XM_536151 ⟹ XP_536151

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	38	16,971,449 - 16,990,673 (+)	NCBI
Dog10K_Boxer_Tasha	38	17,027,790 - 17,047,007 (+)	NCBI

Sequence:

show sequence

TGCCGCCTCGGTAGCTGTCATGGCGGCCCGGGCCACGTGACCGCGGCTCGGCGCAGGCCGCTCG
GGCTCGGCCTCCCTCCCCTTCTCGTCCGCCGACTCGGATCCTGCCTTTCTTCCCTCCGGAAGAC
GGCCGCACCGACTCCCGAGAAACCCGGAGACAGCTGGAGAAAATGACACATTGGTTTCATAGGA
ACCCATTAAAAGCCACAGCTCCCGTTGCTTTTAACTACTATGGTGTAGCTGCTGGTCCTGCCGC
TTCAAAAATTTGCAGTGACTTGAGATCATCCAGAGCACGACTGCTCGAACTCTTCACTGATTTG
AGCTGTAATCCAGAAATGATGAAGAATGCAGCAGATTCCTATTTTTCACTTTTACAAGGTTTCA
TAAATTCATTGGATGAATCTACCCAAGAGAGCAAGTTACGATATATTCAAAATTTCAAGTGGAC
TGATACATTACAAGGACAGGTTCCAAGTGCCCAGCAGGATGCTGTTTTTGAATTAATTTCCATG
GGATTTAATGTAGCTTTATGGTATACCAAATATGCTTCAAGACTGGCTGGAAAAGAAAACATAA
CAGAAGATGAAGCAAAAGAAGTCCATCGAAGCCTAAAAATTGCAGCGGGGATTTTTAAACATTT
AAAGGAAAGTCAGATCCCAAAGCTTATTACACCTGCAGAAAAGGGGAGGGACTTAGAGGCACGA
CTTCTAGAAGCTTATGTTGTCCAGTGTCAGGCTGAAGCTCAAGAAGTAACAATTGCTCGAGCCA
TTGAACTGAAACATGCTCCTGGGCTTATTGCTGCCCTGGCATATGAAACTGCCAACTTCTATCA
AAAAGCTGATCATACTTTATCCAGTTTGGAGCCTGCTTATTCTGCTAAATGGAGAAAATATCTT
CACTTGAAAATGTGTTTCTACACAGCTTATGCTTACTGTTATCATGGTCAAACTTTGTTGGCTA
GTGATAAATGTGGTGAAGCAATCAGGTCTCTCCAAGAAGCAGAAAAATTTTATGCAAAGGCAGA
AGCATTGTGCAAAGAATATGGAGAAACCAAAGGACCTGGGCCAACAGTCAAACCTTCAGGACAC
TTATTCTTTAGGAGACTTGGAAATCTTGTGAAGAATACCCTCGAGAAATGTCAGAGAGAAAATG
GATTTATTTACTTTCAAAAAATTCCAACAGAAGCCCCACAGCTGGAACTCAAAGCAAATTATGG
TCTCGTAGAGCCAGTACCTTTTGAATTTCCTCCTACAAGTGCATACTGGACACCAGACACACTG
GCTGCATTTGATCTCACCAAAAGACCCAAGGATGACAGTACCAAATCCAAACCAGAAGAAACGG
TGAAACCTGTGAAAGAGCCAGATATCAAACCTCAGAAGGACACAGGGTGCTCCATCTCCTAAAG
TACATTGATAAAATGTGCACTTTGAATTTCTCTACTAGTGGATGAGATAAACCGTGGAAGTTCA
GTTCCTATTTCTTGAAGTGTTTTGTCTGAAGCCTGTAGAATGATTTAGTACATTCAGAGGGAAT
CTGCCTTCAGTTTATTTGTTCTTGATTTTTAATATAGTAGAGATGTCTCATGCTTTGTTTCCAG
ACTCCTTTTCAATCAGGACAACATGTAAGGATTTTATTGTGCATATTAGGTTGAAGGGCATATT
AGGTTGTTGGTTTTTGTCTCCGAACTCTGGGTAGAAATAAGTTTTGGTTAATGTATTACAGGCC
AGAATCATGTGGTTTCAGGTATCTTTTTCTGTCTTCACACACAAAAGTTTATCATCTTTTGACA
CCAGAAGAATGACAGGAGTTGGTTTTTCAGAGTTTTTCCCCCCTCACCATTATGTTGTCTCACA
GACTTGTTATGTTCTGAGTCCATTATCTTTTCTGGTGGGAAAATCATTTACAGTTAAGGATCAG
AAAATCTTCATACCAAATTCCTTACATATGTAAGAAGCTATAATTTGTTCCAGTATCACTGTTC
ATAGGTATTTTGAGGCCATTTAGGAACTTACTCCAGGGGTGCCTGGCTGGTTCAGTGGGAGGGA
GCATGTGACTCTTGATCGTGGGGTTCTGAGTTCAAGCGCCATGTTGGACATAGAGGTAACGTAG
ATAAATAAATGAATCTTAAAAAAAAAAAAAATACTCCTCTTCTGGTAGCCCTGCACTTTATTTC
AGTCTCAATAAACATATAGTGATTTTTACAGCTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005640895	(Get FASTA)	NCBI Sequence Viewer
	XP_005640896	(Get FASTA)	NCBI Sequence Viewer
	XP_038304428	(Get FASTA)	NCBI Sequence Viewer
	XP_038304429	(Get FASTA)	NCBI Sequence Viewer
	XP_038304430	(Get FASTA)	NCBI Sequence Viewer
	XP_038378334	(Get FASTA)	NCBI Sequence Viewer
	XP_038378335	(Get FASTA)	NCBI Sequence Viewer
	XP_038378336	(Get FASTA)	NCBI Sequence Viewer
	XP_038442133	(Get FASTA)	NCBI Sequence Viewer
	XP_038442134	(Get FASTA)	NCBI Sequence Viewer
	XP_038442135	(Get FASTA)	NCBI Sequence Viewer
	XP_038506540	(Get FASTA)	NCBI Sequence Viewer
	XP_038506541	(Get FASTA)	NCBI Sequence Viewer
	XP_038506542	(Get FASTA)	NCBI Sequence Viewer
	XP_536151	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000019917.4
	ENSCAFP00000043541.2
	ENSCAFP00000063984.2
	ENSCAFP00000069732.1
	ENSCAFP00030033492.1
	ENSCAFP00030033570.1
	ENSCAFP00030033657.1
	ENSCAFP00030033712.1
	ENSCAFP00040027878.1
	ENSCAFP00040027946.1
	ENSCAFP00040028025.1
	ENSCAFP00845042557.1
	ENSCAFP00845042569.1
	ENSCAFP00845042574
	ENSCAFP00845042574.1
	ENSCAFP00845042589.1

RefSeq Acc Id:

XP_536151 ⟸ XM_536151

- UniProtKB:

A0A8C0JP62 (UniProtKB/TrEMBL), A0A8C0P412 (UniProtKB/TrEMBL), A0A8P0PJ87 (UniProtKB/TrEMBL), A0A8C0PA07 (UniProtKB/TrEMBL), A0A8P0NU04 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTHWFHRNPLKATAPVAFNYYGVAAGPAASKICSDLRSSRARLLELFTDLSCNPEMMKNAADSY
FSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQVPSAQQDAVFELISMGFNVALWYTKYASR
LAGKENITEDEAKEVHRSLKIAAGIFKHLKESQIPKLITPAEKGRDLEARLLEAYVVQCQAEAQ
EVTIARAIELKHAPGLIAALAYETANFYQKADHTLSSLEPAYSAKWRKYLHLKMCFYTAYAYCY
HGQTLLASDKCGEAIRSLQEAEKFYAKAEALCKEYGETKGPGPTVKPSGHLFFRRLGNLVKNTL
EKCQRENGFIYFQKIPTEAPQLELKANYGLVEPVPFEFPPTSAYWTPDTLAAFDLTKRPKDDST
KSKPEETVKPVKEPDIKPQKDTGCSIS

hide sequence

RefSeq Acc Id:

XP_005640895 ⟸ XM_005640838

- UniProtKB:

A0A8C0JP62 (UniProtKB/TrEMBL), A0A8C0P412 (UniProtKB/TrEMBL), A0A8P0PJ87 (UniProtKB/TrEMBL), A0A8C0PA07 (UniProtKB/TrEMBL), A0A8P0NU04 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTHWFHRNPLKATAPVAFNYYGVAAGPAASKICSDLRSSRARLLELFTDLSCNPEMMKNAADSY
FSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQVPSAQQDAVFELISMGFNVALWYTKYASR
LAGKENITEDEAKEVHRSLKIAAGIFKHLKESQIPKLITPAEKGRDLEARLLEAYVVQCQAEAQ
EVTIARAIELKHAPGLIAALAYETANFYQKADHTLSSLEPAYSAKWRKYLHLKMCFYTAYAYCY
HGQTLLASDKCGEAIRSLQEAEKFYAKAEALCKEYGETKGPGPTVKPSGHLFFRRLGNLVKNTL
EKCQRENGFIYFQKIPTEAPQLELKANYGLVEPVPFEFPPTSAYWTPDTLAAFDLTKRPKDDST
KSKPEETVKPVKEPDIKPQKDTGCSIS

hide sequence

RefSeq Acc Id:

XP_005640896 ⟸ XM_005640839

- UniProtKB:

A0A8C0JP62 (UniProtKB/TrEMBL), A0A8C0P412 (UniProtKB/TrEMBL), A0A8P0PJ87 (UniProtKB/TrEMBL), A0A8C0PA07 (UniProtKB/TrEMBL), A0A8P0NU04 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTHWFHRNPLKATAPVAFNYYGVAAGPAASKICSDLRSSRARLLELFTDLSCNPEMMKNAADSY
FSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQVPSAQQDAVFELISMGFNVALWYTKYASR
LAGKENITEDEAKEVHRSLKIAAGIFKHLKESQIPKLITPAEKGRDLEARLLEAYVVQCQAEAQ
EVTIARAIELKHAPGLIAALAYETANFYQKADHTLSSLEPAYSAKWRKYLHLKMCFYTAYAYCY
HGQTLLASDKCGEAIRSLQEAEKFYAKAEALCKEYGETKGPGPTVKPSGHLFFRRLGNLVKNTL
EKCQRENGFIYFQKIPTEAPQLELKANYGLVEPVPFEFPPTSAYWTPDTLAAFDLTKRPKDDST
KSKPEETVKPVKEPDIKPQKDTGCSIS

hide sequence

RefSeq Acc Id:

ENSCAFP00000019917 ⟸ ENSCAFT00000021449

RefSeq Acc Id:

ENSCAFP00000063984 ⟸ ENSCAFT00000075979

RefSeq Acc Id:

ENSCAFP00000043541 ⟸ ENSCAFT00000081000

RefSeq Acc Id:

XP_038378334 ⟸ XM_038522406

RefSeq Acc Id:

XP_038378335 ⟸ XM_038522407

RefSeq Acc Id:

XP_038378336 ⟸ XM_038522408

RefSeq Acc Id:

XP_038506541 ⟸ XM_038650613

RefSeq Acc Id:

XP_038506540 ⟸ XM_038650612

RefSeq Acc Id:

XP_038506542 ⟸ XM_038650614

RefSeq Acc Id:	XP_038304429 ⟸ XM_038448501
- UniProtKB:	A0A8I3SCQ3 (UniProtKB/TrEMBL), A0A8I3Q4M3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038304428 ⟸ XM_038448500
- UniProtKB:	A0A8I3SCQ3 (UniProtKB/TrEMBL), A0A8I3Q4M3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038304430 ⟸ XM_038448502
- UniProtKB:	A0A8I3SCQ3 (UniProtKB/TrEMBL), A0A8I3Q4M3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038442134 ⟸ XM_038586206
- UniProtKB:	A0A8C0JP62 (UniProtKB/TrEMBL), A0A8C0P412 (UniProtKB/TrEMBL), A0A8C0PA07 (UniProtKB/TrEMBL), A0A8P0NU04 (UniProtKB/TrEMBL), A0A8P0PJ87 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038442133 ⟸ XM_038586205
- UniProtKB:	A0A8C0JP62 (UniProtKB/TrEMBL), A0A8C0P412 (UniProtKB/TrEMBL), A0A8C0PA07 (UniProtKB/TrEMBL), A0A8P0NU04 (UniProtKB/TrEMBL), A0A8P0PJ87 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038442135 ⟸ XM_038586207
- UniProtKB:	A0A8C0JP62 (UniProtKB/TrEMBL), A0A8C0P412 (UniProtKB/TrEMBL), A0A8C0PA07 (UniProtKB/TrEMBL), A0A8P0NU04 (UniProtKB/TrEMBL), A0A8P0PJ87 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845042574 ⟸ ENSCAFT00845054190

RefSeq Acc Id:

ENSCAFP00845042589 ⟸ ENSCAFT00845054210

RefSeq Acc Id:

ENSCAFP00845042569 ⟸ ENSCAFT00845054180

RefSeq Acc Id:

ENSCAFP00845042557 ⟸ ENSCAFT00845054164

Protein Domains

BRO1

Promoters

RGD ID:

13689200

Promoter ID:

EPDNEW_C7269

Type:

initiation region

Name:

BROX_1

Description:

BRO1 domain and CAAX motif containing

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	38	16,971,527 - 16,971,587	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000013516	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030020924	UniProtKB/TrEMBL
	ENSCAFG00040017364	UniProtKB/TrEMBL
	ENSCAFG00845030521	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000021449.5	UniProtKB/TrEMBL
	ENSCAFT00000075979.2	UniProtKB/TrEMBL
	ENSCAFT00000081000.2	UniProtKB/TrEMBL
	ENSCAFT00000107107.1	UniProtKB/TrEMBL
	ENSCAFT00030038391.1	UniProtKB/TrEMBL
	ENSCAFT00030038478.1	UniProtKB/TrEMBL
	ENSCAFT00030038580.1	UniProtKB/TrEMBL
	ENSCAFT00030038635.1	UniProtKB/TrEMBL
	ENSCAFT00040032074.1	UniProtKB/TrEMBL
	ENSCAFT00040032146.1	UniProtKB/TrEMBL
	ENSCAFT00040032228.1	UniProtKB/TrEMBL
	ENSCAFT00845054164.1	UniProtKB/TrEMBL
	ENSCAFT00845054180.1	UniProtKB/TrEMBL
	ENSCAFT00845054190	ENTREZGENE
	ENSCAFT00845054190.1	UniProtKB/TrEMBL
	ENSCAFT00845054210.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.280	UniProtKB/TrEMBL
InterPro	BRO1_dom	UniProtKB/TrEMBL
	BRO1_sf	UniProtKB/TrEMBL
	BROX	UniProtKB/TrEMBL
NCBI Gene	BROX	ENTREZGENE
PANTHER	BRO1 DOMAIN-CONTAINING PROTEIN BROX	UniProtKB/TrEMBL
	PTHR23032	UniProtKB/TrEMBL
Pfam	BRO1	UniProtKB/TrEMBL
PROSITE	BRO1	UniProtKB/TrEMBL
SMART	BRO1	UniProtKB/TrEMBL
UniProt	A0A8C0JP62	ENTREZGENE
	A0A8C0NZ49_CANLF	UniProtKB/TrEMBL
	A0A8C0P412	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0PA07	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0Z0L7_CANLF	UniProtKB/TrEMBL
	A0A8I3Q4M3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3QQU0_CANLF	UniProtKB/TrEMBL
	A0A8I3QR44_CANLF	UniProtKB/TrEMBL
	A0A8I3SCQ3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NU04	ENTREZGENE
	A0A8P0PJ87	ENTREZGENE
UniProt Secondary	A0A8P0NFA2	UniProtKB/TrEMBL
	A0A8P0NU04	UniProtKB/TrEMBL
	A0A8P0PCM0	UniProtKB/TrEMBL
	A0A8P0PJ87	UniProtKB/TrEMBL
VGNC ID	VGNC:38532	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar