RAPGEFL1 (Rap guanine nucleotide exchange factor like 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: RAPGEFL1 (Rap guanine nucleotide exchange factor like 1) Canis lupus familiaris
Analyze
Symbol: RAPGEFL1
Name: Rap guanine nucleotide exchange factor like 1
RGD ID: 12353637
Description: ENCODES a protein that exhibits growth factor binding (inferred); guanyl-nucleotide exchange factor activity (inferred); insulin-like growth factor binding (inferred); INVOLVED IN Ras protein signal transduction (inferred); regulation of insulin-like growth factor receptor signaling pathway (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH familial cold autoinflammatory syndrome 2 (ortholog); genetic disease (ortholog); hypertrophic cardiomyopathy 25 (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC106559290; rap guanine nucleotide exchange factor-like 1; uncharacterized LOC106559290
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1922,385,970 - 22,399,584 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl922,387,786 - 22,394,887 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha921,846,496 - 21,871,864 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0923,166,995 - 23,192,372 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl923,167,166 - 23,192,844 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1921,940,814 - 21,966,167 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0922,199,543 - 22,224,894 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0922,324,485 - 22,349,849 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RAPGEFL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1922,385,970 - 22,399,584 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl922,387,786 - 22,394,887 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha921,846,496 - 21,871,864 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0923,166,995 - 23,192,372 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl923,167,166 - 23,192,844 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1921,940,814 - 21,966,167 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0922,199,543 - 22,224,894 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0922,324,485 - 22,349,849 (-)NCBIUU_Cfam_GSD_1.0
RAPGEFL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381740,177,010 - 40,195,650 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1740,177,010 - 40,195,656 (+)EnsemblGRCh38hg38GRCh38
GRCh371738,333,263 - 38,351,902 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361735,591,394 - 35,605,426 (+)NCBINCBI36Build 36hg18NCBI36
Build 341735,588,138 - 35,605,426NCBI
Celera1734,994,758 - 35,012,421 (+)NCBICelera
Cytogenetic Map17q21.1NCBI
HuRef1734,127,434 - 34,145,100 (+)NCBIHuRef
CHM1_11738,569,927 - 38,587,592 (+)NCBICHM1_1
T2T-CHM13v2.01741,040,889 - 41,059,520 (+)NCBIT2T-CHM13v2.0
Rapgefl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391198,727,611 - 98,744,519 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1198,727,611 - 98,744,523 (+)EnsemblGRCm39 Ensembl
GRCm381198,836,785 - 98,853,009 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1198,836,785 - 98,853,697 (+)EnsemblGRCm38mm10GRCm38
MGSCv371198,698,099 - 98,714,319 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361198,653,244 - 98,669,095 (+)NCBIMGSCv36mm8
Celera11108,491,920 - 108,508,404 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1162.7NCBI
Rapgefl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81084,289,980 - 84,306,614 (+)NCBIGRCr8
mRatBN7.21083,793,711 - 83,810,373 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1083,793,694 - 83,810,371 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01086,749,220 - 86,765,677 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1086,763,117 - 86,765,675 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01086,545,478 - 86,561,332 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41087,607,651 - 87,620,668 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1082,541,374 - 82,554,813 (+)NCBICelera
Cytogenetic Map10q31NCBI
Rapgefl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545114,809,630 - 14,816,762 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545114,802,094 - 14,818,096 (+)NCBIChiLan1.0ChiLan1.0
RAPGEFL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21924,759,538 - 24,777,374 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11726,654,350 - 26,672,187 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01717,093,714 - 17,111,187 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11717,315,114 - 17,335,258 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1717,315,114 - 17,335,258 (-)Ensemblpanpan1.1panPan2
Rapgefl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560221,779,660 - 21,793,695 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649015,281,433 - 15,296,636 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649015,281,462 - 15,295,479 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAPGEFL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1222,181,849 - 22,195,840 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11222,180,928 - 22,195,841 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21222,546,729 - 22,561,648 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAPGEFL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11665,978,561 - 65,995,738 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607736,883,727 - 36,901,319 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rapgefl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247953,036,543 - 3,045,595 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247953,036,245 - 3,045,610 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RAPGEFL1
87 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 2 6 6
Low 3 11 1 1 6 8 5
Below cutoff 5 11 5 6 5 6 5 6

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_038485625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038603385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038603394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038603413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038603423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_548135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000043469   ⟹   ENSCAFP00000036923
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl922,387,786 - 22,394,887 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845016406   ⟹   ENSCAFP00845012762
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl923,167,166 - 23,192,447 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845016515   ⟹   ENSCAFP00845012845
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl923,178,753 - 23,192,844 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845016575   ⟹   ENSCAFP00845012894
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl923,178,753 - 23,192,664 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845016615   ⟹   ENSCAFP00845012925
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl923,178,753 - 23,192,447 (-)Ensembl
RefSeq Acc Id: XM_038485625   ⟹   XP_038341553
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1921,940,814 - 21,966,167 (-)NCBI
RefSeq Acc Id: XM_038485626   ⟹   XP_038341554
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1921,940,814 - 21,966,167 (-)NCBI
RefSeq Acc Id: XM_038485627   ⟹   XP_038341555
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1921,940,814 - 21,966,167 (-)NCBI
RefSeq Acc Id: XM_038485628   ⟹   XP_038341556
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1921,940,814 - 21,966,167 (-)NCBI
RefSeq Acc Id: XM_038485629   ⟹   XP_038341557
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1921,940,814 - 21,966,167 (-)NCBI
RefSeq Acc Id: XM_038547392   ⟹   XP_038403320
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0922,324,485 - 22,349,849 (-)NCBI
RefSeq Acc Id: XM_038547393   ⟹   XP_038403321
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0922,324,485 - 22,349,849 (-)NCBI
RefSeq Acc Id: XM_038547394   ⟹   XP_038403322
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0922,324,485 - 22,349,849 (-)NCBI
RefSeq Acc Id: XM_038547395   ⟹   XP_038403323
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0922,324,485 - 22,349,849 (-)NCBI
RefSeq Acc Id: XM_038547396   ⟹   XP_038403324
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0922,324,485 - 22,349,849 (-)NCBI
RefSeq Acc Id: XM_038603385   ⟹   XP_038459313
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha921,846,496 - 21,871,864 (-)NCBI
RefSeq Acc Id: XM_038603394   ⟹   XP_038459322
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha921,846,496 - 21,871,864 (-)NCBI
RefSeq Acc Id: XM_038603413   ⟹   XP_038459341
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha921,846,496 - 21,871,864 (-)NCBI
RefSeq Acc Id: XM_038603423   ⟹   XP_038459351
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha921,846,496 - 21,871,864 (-)NCBI
RefSeq Acc Id: XM_038611376   ⟹   XP_038467304
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0922,199,543 - 22,224,894 (-)NCBI
RefSeq Acc Id: XM_038611377   ⟹   XP_038467305
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0922,199,543 - 22,224,894 (-)NCBI
RefSeq Acc Id: XM_038611378   ⟹   XP_038467306
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0922,199,543 - 22,224,894 (-)NCBI
RefSeq Acc Id: XM_038611379   ⟹   XP_038467307
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0922,199,543 - 22,224,894 (-)NCBI
RefSeq Acc Id: XM_038611380   ⟹   XP_038467308
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0922,199,543 - 22,224,894 (-)NCBI
RefSeq Acc Id: XM_038676569   ⟹   XP_038532497
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0923,166,995 - 23,192,372 (-)NCBI
RefSeq Acc Id: XM_038676570   ⟹   XP_038532498
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0923,166,995 - 23,192,372 (-)NCBI
RefSeq Acc Id: XM_038676571   ⟹   XP_038532499
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0923,166,995 - 23,192,372 (-)NCBI
RefSeq Acc Id: XM_038676572   ⟹   XP_038532500
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0923,166,995 - 23,192,372 (-)NCBI
RefSeq Acc Id: XM_038676573   ⟹   XP_038532501
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0923,166,995 - 23,192,372 (-)NCBI
RefSeq Acc Id: XM_548135   ⟹   XP_548135
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1922,385,970 - 22,399,584 (-)NCBI
Dog10K_Boxer_Tasha921,846,496 - 21,871,864 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038341553 (Get FASTA)   NCBI Sequence Viewer  
  XP_038341554 (Get FASTA)   NCBI Sequence Viewer  
  XP_038341555 (Get FASTA)   NCBI Sequence Viewer  
  XP_038341556 (Get FASTA)   NCBI Sequence Viewer  
  XP_038341557 (Get FASTA)   NCBI Sequence Viewer  
  XP_038403320 (Get FASTA)   NCBI Sequence Viewer  
  XP_038403321 (Get FASTA)   NCBI Sequence Viewer  
  XP_038403322 (Get FASTA)   NCBI Sequence Viewer  
  XP_038403323 (Get FASTA)   NCBI Sequence Viewer  
  XP_038403324 (Get FASTA)   NCBI Sequence Viewer  
  XP_038459313 (Get FASTA)   NCBI Sequence Viewer  
  XP_038459322 (Get FASTA)   NCBI Sequence Viewer  
  XP_038459341 (Get FASTA)   NCBI Sequence Viewer  
  XP_038459351 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467304 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467305 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467306 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467307 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467308 (Get FASTA)   NCBI Sequence Viewer  
  XP_038532497 (Get FASTA)   NCBI Sequence Viewer  
  XP_038532498 (Get FASTA)   NCBI Sequence Viewer  
  XP_038532499 (Get FASTA)   NCBI Sequence Viewer  
  XP_038532500 (Get FASTA)   NCBI Sequence Viewer  
  XP_038532501 (Get FASTA)   NCBI Sequence Viewer  
  XP_548135 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000036923.3
  ENSCAFP00000068539.1
  ENSCAFP00000070711.1
  ENSCAFP00000073350.1
  ENSCAFP00000074562.1
  ENSCAFP00030023994.1
  ENSCAFP00030024068.1
  ENSCAFP00030024180.1
  ENSCAFP00030024253.1
  ENSCAFP00040000593.1
  ENSCAFP00040000627.1
  ENSCAFP00040000634.1
  ENSCAFP00845012762
  ENSCAFP00845012762.1
  ENSCAFP00845012845.1
  ENSCAFP00845012894.1
  ENSCAFP00845012925
  ENSCAFP00845012925.1
Reference Protein Sequences
RefSeq Acc Id: XP_548135   ⟸   XM_548135
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RKM4 (UniProtKB/TrEMBL),   A0A8I3NN70 (UniProtKB/TrEMBL),   A0A8C0KXX7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000036923   ⟸   ENSCAFT00000043469
RefSeq Acc Id: XP_038341557   ⟸   XM_038485629
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038341555   ⟸   XM_038485627
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038341556   ⟸   XM_038485628
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038341554   ⟸   XM_038485626
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038341553   ⟸   XM_038485625
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038467308   ⟸   XM_038611380
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038467306   ⟸   XM_038611378
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038467307   ⟸   XM_038611379
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038467305   ⟸   XM_038611377
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038467304   ⟸   XM_038611376
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038532501   ⟸   XM_038676573
- Peptide Label: isoform X4
- UniProtKB: A0A8I3N7I9 (UniProtKB/TrEMBL),   A0A8P0TNV2 (UniProtKB/TrEMBL),   A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038532499   ⟸   XM_038676571
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RKM4 (UniProtKB/TrEMBL),   A0A8I3NN70 (UniProtKB/TrEMBL),   A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038532500   ⟸   XM_038676572
- Peptide Label: isoform X3
- UniProtKB: A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038532498   ⟸   XM_038676570
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038532497   ⟸   XM_038676569
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038459351   ⟸   XM_038603423
- Peptide Label: isoform X4
- UniProtKB: A0A8I3N7I9 (UniProtKB/TrEMBL),   A0A8P0TNV2 (UniProtKB/TrEMBL),   A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038459341   ⟸   XM_038603413
- Peptide Label: isoform X3
- UniProtKB: A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038459322   ⟸   XM_038603394
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038459313   ⟸   XM_038603385
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403324   ⟸   XM_038547396
- Peptide Label: isoform X4
- UniProtKB: A0A8C0KXX7 (UniProtKB/TrEMBL),   A0A8I3N7I9 (UniProtKB/TrEMBL),   A0A8P0TNV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403322   ⟸   XM_038547394
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KXX7 (UniProtKB/TrEMBL),   A0A8C0RKM4 (UniProtKB/TrEMBL),   A0A8I3NN70 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403323   ⟸   XM_038547395
- Peptide Label: isoform X3
- UniProtKB: A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403321   ⟸   XM_038547393
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403320   ⟸   XM_038547392
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KXX7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845012925   ⟸   ENSCAFT00845016615
RefSeq Acc Id: ENSCAFP00845012894   ⟸   ENSCAFT00845016575
RefSeq Acc Id: ENSCAFP00845012845   ⟸   ENSCAFT00845016515
RefSeq Acc Id: ENSCAFP00845012762   ⟸   ENSCAFT00845016406
Protein Domains
IGFBP N-terminal   Ras-GEF   Thyroglobulin type-1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000032290 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030014759 UniProtKB/TrEMBL
  ENSCAFG00040000334 UniProtKB/TrEMBL
  ENSCAFG00845009161 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000043469.3 UniProtKB/TrEMBL
  ENSCAFT00000094924.1 UniProtKB/TrEMBL
  ENSCAFT00000102062.1 UniProtKB/TrEMBL
  ENSCAFT00000104477.1 UniProtKB/TrEMBL
  ENSCAFT00000109877.1 UniProtKB/TrEMBL
  ENSCAFT00030027499.1 UniProtKB/TrEMBL
  ENSCAFT00030027582.1 UniProtKB/TrEMBL
  ENSCAFT00030027707.1 UniProtKB/TrEMBL
  ENSCAFT00030027791.1 UniProtKB/TrEMBL
  ENSCAFT00040000705.1 UniProtKB/TrEMBL
  ENSCAFT00040000745.1 UniProtKB/TrEMBL
  ENSCAFT00040000753.1 UniProtKB/TrEMBL
  ENSCAFT00845016406 ENTREZGENE
  ENSCAFT00845016406.1 UniProtKB/TrEMBL
  ENSCAFT00845016515.1 UniProtKB/TrEMBL
  ENSCAFT00845016575.1 UniProtKB/TrEMBL
  ENSCAFT00845016615 ENTREZGENE
  ENSCAFT00845016615.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.840.10 UniProtKB/TrEMBL
  4.10.40.20 UniProtKB/TrEMBL
  Son of sevenless (SoS) protein Chain: S domain 1 UniProtKB/TrEMBL
  Thyroglobulin type-1 UniProtKB/TrEMBL
InterPro Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  IGFBP-4 UniProtKB/TrEMBL
  IGFBP-like UniProtKB/TrEMBL
  IGFBP_1-6_chordata UniProtKB/TrEMBL
  Insulin_GF-bd_Cys-rich_CS UniProtKB/TrEMBL
  Ras-like_GEF UniProtKB/TrEMBL
  Ras_GEF_dom_sf UniProtKB/TrEMBL
  RASGEF_cat_dom UniProtKB/TrEMBL
  RASGEF_cat_dom_sf UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
  Thyroglobulin_1_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene RAPGEFL1 ENTREZGENE
PANTHER INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN UniProtKB/TrEMBL
  INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 4 UniProtKB/TrEMBL
  PTHR23113 UniProtKB/TrEMBL
  RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR-LIKE 1 UniProtKB/TrEMBL
Pfam IGFBP UniProtKB/TrEMBL
  RasGEF UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
PRINTS IGFBPFAMILY UniProtKB/TrEMBL
  IGFBPFAMILY4 UniProtKB/TrEMBL
PROSITE IGFBP_N_1 UniProtKB/TrEMBL
  IGFBP_N_2 UniProtKB/TrEMBL
  RASGEF_CAT UniProtKB/TrEMBL
  THYROGLOBULIN_1_2 UniProtKB/TrEMBL
SMART RasGEF UniProtKB/TrEMBL
  SM00121 UniProtKB/TrEMBL
  SM00211 UniProtKB/TrEMBL
Superfamily-SCOP Growth factor receptor domain UniProtKB/TrEMBL
  SSF48366 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
  Thyroglobulin type-1 domain UniProtKB/TrEMBL
UniProt A0A8C0KXX7 ENTREZGENE
  A0A8C0NGH5_CANLF UniProtKB/TrEMBL
  A0A8C0PMI7_CANLF UniProtKB/TrEMBL
  A0A8C0Q1X2_CANLF UniProtKB/TrEMBL
  A0A8C0RKM4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RUP5_CANLF UniProtKB/TrEMBL
  A0A8I3N113_CANLF UniProtKB/TrEMBL
  A0A8I3N149_CANLF UniProtKB/TrEMBL
  A0A8I3N7I9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NN70 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TKH0_CANLF UniProtKB/TrEMBL
  A0A8P0TNV2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8P0SRS2 UniProtKB/TrEMBL
VGNC ID VGNC:111691 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-14 RAPGEFL1  Rap guanine nucleotide exchange factor like 1  LOC106559290  uncharacterized LOC106559290  Data merged from RGD:12293674 737654 PROVISIONAL