FUCA1 (alpha-L-fucosidase 1) - Rat Genome Database

Name: FUCA1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: FUCA1 (alpha-L-fucosidase 1) Canis lupus familiaris

Analyze

Symbol:

FUCA1

Name:

alpha-L-fucosidase 1

RGD ID:

12350565

Description:

ENCODES a protein that exhibits carbohydrate binding (ortholog); fucosidase activity (ortholog); INVOLVED IN fucose metabolic process (inferred); glycoside catabolic process (inferred); lipid metabolic process (inferred); ASSOCIATED WITH fucosidosis; 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (ortholog); diabetes mellitus (ortholog); FOUND IN intracellular membrane-bounded organelle (inferred); lysosome (inferred)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

alpha-L-fucosidase I; alpha-L-fucoside fucohydrolase 1; fucosidase, alpha-L- 1, tissue; tissue alpha-L-fucosidase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FUCA1 (alpha-L-fucosidase 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Fuca1 (fucosidase, alpha-L- 1, tissue)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Fuca1 (alpha-L-fucosidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Fuca1 (alpha-L-fucosidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FUCA1 (alpha-L-fucosidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fuca1 (alpha-L-fucosidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FUCA1 (alpha-L-fucosidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOC103225962 (alpha-L-fucosidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Fuca1 (alpha-L-fucosidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	75,665,473 - 75,677,087 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	75,665,469 - 75,688,629 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	72,235,627 - 72,247,237 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	76,224,732 - 76,236,351 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	76,224,694 - 76,243,380 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	73,047,152 - 73,058,769 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	74,053,782 - 74,065,389 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	75,059,639 - 75,071,248 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (ISO)

diabetes mellitus (ISO)

Diabetic Nephropathies (ISO)

diabetic retinopathy (ISO)

Experimental Diabetes Mellitus (ISO)

fucosidosis (IAGP,ISO)

genetic disease (ISO)

intellectual disability (ISO)

Nervous System Malformations (ISO)

type 1 diabetes mellitus (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fucose metabolic process (IBA,IEA)

glycoside catabolic process (IBA,IEA)

lipid metabolic process (IEA)

Cellular Component

intracellular membrane-bounded organelle (IEA)

lysosome (IBA,IEA)

Molecular Function

alpha-L-fucosidase activity (IBA,IEA)

carbohydrate binding (ISO)

fucosidase activity (IEA,ISO)

hydrolase activity, acting on glycosyl bonds (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:8661697	PMID:8730282	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

FUCA1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	75,665,473 - 75,677,087 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	75,665,469 - 75,688,629 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	72,235,627 - 72,247,237 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	76,224,732 - 76,236,351 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	76,224,694 - 76,243,380 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	73,047,152 - 73,058,769 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	74,053,782 - 74,065,389 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	75,059,639 - 75,071,248 (+)	NCBI		UU_Cfam_GSD_1.0

FUCA1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	23,845,077 - 23,868,290 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	23,845,077 - 23,868,290 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	24,171,567 - 24,194,780 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	24,044,154 - 24,067,408 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	23,916,879 - 23,940,079	NCBI
Celera	1	22,500,442 - 22,523,489 (-)	NCBI		Celera
Cytogenetic Map	1	p36.11	NCBI
HuRef	1	22,423,234 - 22,446,489 (-)	NCBI		HuRef
CHM1_1	1	24,284,300 - 24,307,588 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	23,680,157 - 23,703,377 (-)	NCBI		T2T-CHM13v2.0

Fuca1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	135,648,037 - 135,667,611 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	135,648,046 - 135,667,622 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	135,920,726 - 135,940,300 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	135,920,735 - 135,940,311 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	135,476,641 - 135,496,215 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	135,192,833 - 135,212,389 (+)	NCBI		MGSCv36	mm8
Celera	4	134,121,527 - 134,141,456 (+)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	68.01	NCBI

Fuca1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	153,436,262 - 153,453,512 (+)	NCBI		GRCr8
mRatBN7.2	5	148,152,718 - 148,169,972 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	148,152,700 - 148,169,972 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	150,851,447 - 150,868,992 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	152,625,717 - 152,643,262 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	152,607,730 - 152,625,275 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	154,269,296 - 154,286,545 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	154,269,118 - 154,286,544 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	158,034,147 - 158,051,397 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	154,703,722 - 154,720,971 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	154,713,770 - 154,731,009 (+)	NCBI
Celera	5	146,559,858 - 146,577,113 (+)	NCBI		Celera
RH 3.4 Map	5	1003.4	RGD
Cytogenetic Map	5	q36	NCBI

Fuca1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	3,744,755 - 3,759,676 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	3,744,071 - 3,759,776 (-)	NCBI	ChiLan1.0	ChiLan1.0

FUCA1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	203,072,184 - 203,093,659 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	202,175,209 - 202,196,548 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	23,039,126 - 23,060,514 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	24,022,960 - 24,043,850 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	24,022,967 - 24,043,850 (-)	Ensembl	panpan1.1		panPan2

Fuca1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	43,170,743 - 43,187,687 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	8,996,129 - 9,012,310 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	8,995,525 - 9,012,396 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FUCA1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	81,637,994 - 81,656,068 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	81,638,213 - 81,655,993 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	75,370,073 - 75,388,852 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103225962
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	108,823,047 - 108,832,926 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666482	24,561 - 46,953 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fuca1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	8,371,167 - 8,386,134 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	8,371,251 - 8,385,855 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in FUCA1
91 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5	22	6	6	6	6	1	12	8	10	6
Low								5
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001003250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF083034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U29765	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U29766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92672	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92677	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92678	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000020742 ⟹ ENSCAFP00000019256

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	75,665,469 - 75,677,097 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000061803 ⟹ ENSCAFP00000050680

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	75,665,469 - 75,688,629 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000069935 ⟹ ENSCAFP00000052105

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	75,665,469 - 75,688,573 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000071829 ⟹ ENSCAFP00000063934

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	75,665,469 - 75,684,086 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000079131 ⟹ ENSCAFP00000046134

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	75,665,488 - 75,676,464 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000083320 ⟹ ENSCAFP00000045494

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	75,665,469 - 75,676,799 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845026369 ⟹ ENSCAFP00845020785

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	76,224,694 - 76,243,380 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845026404 ⟹ ENSCAFP00845020812

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	76,224,694 - 76,236,366 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845026412 ⟹ ENSCAFP00845020816

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	76,224,694 - 76,236,353 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845026440 ⟹ ENSCAFP00845020837

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	76,224,694 - 76,235,728 (+)	Ensembl

RefSeq Acc Id:

NM_001003250 ⟹ NP_001003250

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	75,665,473 - 75,677,087 (+)	NCBI
Dog10K_Boxer_Tasha	2	72,235,627 - 72,247,237 (+)	NCBI
ROS_Cfam_1.0	2	76,224,732 - 76,236,351 (+)	NCBI
UMICH_Zoey_3.1	2	73,047,152 - 73,058,769 (+)	NCBI
UNSW_CanFamBas_1.0	2	74,053,782 - 74,065,389 (+)	NCBI
UU_Cfam_GSD_1.0	2	75,059,639 - 75,071,248 (+)	NCBI

Sequence:

show sequence

ACGCGGCCTTCGGCGATGAAGCCCTGGGCGGTGGGCCTCGGGCCGCCGCCGCCGCTGCCGCTGC
CGCTGCTGCTGCTGCTGCTGCTCGGCGCGGCGTTGGTGCGCGGGCCGCCGCCTCCGCGCCGCTA
CACCCCGGACTGGCAGAGTCTGGACTCGCGGCCGCTGCCGGACTGGTTCGACAAGGCCAAGTTC
GGGGTGTTCGTGCACTGGGGCGTGTTCGCGGTGCCGGCCTGGGGCAGCGAGTGGTTCTGGTGGC
ACTGGAAGGGCGAGGGGCTGCCGCAGTACGAGCAGTTCATGAGCGAGAACTACCCGCCCGGCTT
CAGCTACGCCGACTTCGGGCCGCAGTTCACGGCGCGCTTCTTCCACCCCGACACCTGGGCCGAC
CTCTTCCAGGCGGCGGGGGCCCGGTATGTAGTCCTGACGACAAAGCACCACGAAGGCTTCACAA
ACTGGCCAAGTTCTGTGTCTTGGAATTGGAACTCTAATGATGTGGGTCCCCATCGTGATTTGGT
TGGTGAGTTGGGAAGAGCCCTCCGGAAGAGGAACATACGTTATGGACTCTACCACTCACTTTTA
GAATGGTTCCACCCACTGTACCTACTTGATAAGAAAAACAACTTCAAAACACAGTTTTTTGTCC
GTGCAAAAACAATGCCAGAACTATATGACCTTGTTAACAGGTATGAACCTGACTTGATTTGGTC
TGATGGAGAGTGGGAATGTCCTGATACTTACTGGAACTCTACAGAGTTTCTTTCTTGGCTCTAC
AATGATAGTCCAGTCAAGGATCACGTAGTGGTAAATGACCGGTGGGGTCAGAACTGTTCCTGTC
ACCATGGAGGATACTACAACTGTCAAGATAAATACAAGCCAGAGAGCTTGCCAGACCACAAGTG
GGAAATGTGTACCTCCATAGACAAGGTCTCCTGGGGCTATCGTCGTAACATGGTGATGTCGGAC
GTTGCAAGTGAATGTGAAATCATCTCGGAACTGGTTCAGACAGTGAGCTTGGGAGGCAACTACC
TCCTCAACATTGGACCAACTAAAGATGGACTGATTGTCCCCATCTTCCAAGAAAGGCTTCTTTC
CATTGGGAAGTGGCTAAGCATCAATGGGGAGGCTATCTATGCCTCTAAACCGTGGAGGGTACAA
CTGGAAAAGAACACGACGTCTGTGTGGTATACCTCAAGAGGAATGACTGTTTATGCCATTTTCC
TGCGCTGGCCAGAAAATGGAGTCTTAAGCCTTAAATCCCCAGTAACTACCTCGACTACACAGAT
AACGATGCTGGGGATCCAGAAAGATCTGAAGTGGTCCACGGAACCAGAAGGTCTGCTCATTTAT
CTGCCCCAGTTATCACTCTTTACTCTGCCAGTTGAGTTTGGTTGGACTATAAAGCTGACAGGAG
TGGAATGATTGTTGGAGTTCAGGAGGAACTGCCTCCTGTTGGCTGCTTTGGTTTTCCTCTTATA
GCACCATCGTTGTAATAAACTACTTCTCTATTCAGAGATGGCTTTTCCAACACATTTTAATCAA
AGGAACTGAGTGCATTATACTGACGTCTCAATGGATCAGAGATCTGAGATCCATTGCTAGCATA
CCTCTCTCTGATCAGCAAGAGGCACTAGCTGGTTAAGCTCTGCGTTCATCCTTCTATTCCTAAC
TTGGGGAATTATCTACCCCAGAAACTTCCCCCCATTACCTTGTGTATGAAACCTATTTCCTTAC
TCAATGACTTCAGATAAAGAATGAGCCAAGTCACCCCATTGCCTATGGAAGAAGGTGAAGAGGA
TCTGGCAATCTCAACCATACGCTGTGTGTTTAGCATCAGTTGTCACCAGCACCCCTCCAAGAGG
AGGAGATCCTGGAAGGGAAGCAAGAGGCTAGCAAGGGCTGCCAATGGTCAGCTCTTTGGAAGTT
TCCATAGCAAACTAGGTGCTCAGAAATTCAGTCTGTTTACAGTGATAGGATGAAGAAAATGAAT
GTGATTCTGCCCTGCTTTTTAAAATATAATCAAATAAATAAATTTTTATGTCAAAT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001003250	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB17401	(Get FASTA)	NCBI Sequence Viewer
	AAB17403	(Get FASTA)	NCBI Sequence Viewer
	AAC32603	(Get FASTA)	NCBI Sequence Viewer
	CAA63197	(Get FASTA)	NCBI Sequence Viewer
	CAA63362	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000019256.3
	ENSCAFP00000046134.1
	ENSCAFP00000063934.1
	ENSCAFP00030001766.1
	ENSCAFP00030001777.1
	ENSCAFP00030001806.1
	ENSCAFP00040002306.1
	ENSCAFP00040002337.1
	ENSCAFP00040002344.1
	ENSCAFP00040002384.1
	ENSCAFP00845020785.1
	ENSCAFP00845020812
	ENSCAFP00845020812.1
	ENSCAFP00845020816.1
	ENSCAFP00845020837.1
GenBank Protein	P48300	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001003250 ⟸ NM_001003250
- Peptide Label:	precursor
- UniProtKB:	A0A8C0PPZ9 (UniProtKB/TrEMBL), A0A8P0SHP0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKPWAVGLGPPPPLPLPLLLLLLLGAALVRGPPPPRRYTPDWQSLDSRPLPDWFDKAKFGVFVH WGVFAVPAWGSEWFWWHWKGEGLPQYEQFMSENYPPGFSYADFGPQFTARFFHPDTWADLFQAA GARYVVLTTKHHEGFTNWPSSVSWNWNSNDVGPHRDLVGELGRALRKRNIRYGLYHSLLEWFHP LYLLDKKNNFKTQFFVRAKTMPELYDLVNRYEPDLIWSDGEWECPDTYWNSTEFLSWLYNDSPV KDHVVVNDRWGQNCSCHHGGYYNCQDKYKPESLPDHKWEMCTSIDKVSWGYRRNMVMSDVASEC EIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLSIGKWLSINGEAIYASKPWRVQLEKNT TSVWYTSRGMTVYAIFLRWPENGVLSLKSPVTTSTTQITMLGIQKDLKWSTEPEGLLIYLPQLS LFTLPVEFGWTIKLTGVE hide sequence

RefSeq Acc Id:

ENSCAFP00000052105 ⟸ ENSCAFT00000069935

RefSeq Acc Id:

ENSCAFP00000046134 ⟸ ENSCAFT00000079131

RefSeq Acc Id:

ENSCAFP00000045494 ⟸ ENSCAFT00000083320

RefSeq Acc Id:

ENSCAFP00000019256 ⟸ ENSCAFT00000020742

RefSeq Acc Id:

ENSCAFP00000050680 ⟸ ENSCAFT00000061803

RefSeq Acc Id:

ENSCAFP00000063934 ⟸ ENSCAFT00000071829

RefSeq Acc Id:

ENSCAFP00845020812 ⟸ ENSCAFT00845026404

RefSeq Acc Id:

ENSCAFP00845020816 ⟸ ENSCAFT00845026412

RefSeq Acc Id:

ENSCAFP00845020837 ⟸ ENSCAFT00845026440

RefSeq Acc Id:

ENSCAFP00845020785 ⟸ ENSCAFT00845026369

Protein Domains

Alpha-L-fucosidase C-terminal

Promoters

RGD ID:

13682601

Promoter ID:

EPDNEW_C670

Type:

initiation region

Name:

FUCA1_1

Description:

alpha-L-fucosidase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	75,665,455 - 75,665,515	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000013073	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030001143	UniProtKB/TrEMBL
	ENSCAFG00040001387	UniProtKB/TrEMBL
	ENSCAFG00845014722	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000020742.5	UniProtKB/TrEMBL
	ENSCAFT00000071829.2	UniProtKB/TrEMBL
	ENSCAFT00000079131.2	UniProtKB/TrEMBL
	ENSCAFT00030001994.1	UniProtKB/TrEMBL
	ENSCAFT00030002005.1	UniProtKB/TrEMBL
	ENSCAFT00030002039.1	UniProtKB/TrEMBL
	ENSCAFT00040002673.1	UniProtKB/TrEMBL
	ENSCAFT00040002708.1	UniProtKB/TrEMBL
	ENSCAFT00040002716.1	UniProtKB/TrEMBL
	ENSCAFT00040002758.1	UniProtKB/TrEMBL
	ENSCAFT00845026369.1	UniProtKB/TrEMBL
	ENSCAFT00845026404	ENTREZGENE
	ENSCAFT00845026404.1	UniProtKB/TrEMBL
	ENSCAFT00845026412.1	UniProtKB/TrEMBL
	ENSCAFT00845026440.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.1180	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glycosidases	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	FUC_metazoa-typ	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Fucosidase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_29	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_29_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glyco_hydro_b	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glycoside_hydrolase_SF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	cfa:403929	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	FUCA1	ENTREZGENE
PANTHER	PTHR10030	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10030:SF2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Alpha_L_fucos	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Fucosidase_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF	Alpha-L-fucosidase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	GLHYDRLASE29	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	ALPHA_L_FUCOSIDASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	Alpha_L_fucos	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF51445	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8C0LUE0_CANLF	UniProtKB/TrEMBL
	A0A8C0PPZ9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0PR47_CANLF	UniProtKB/TrEMBL
	A0A8C0PYG2_CANLF	UniProtKB/TrEMBL
	A0A8C0RA00_CANLF	UniProtKB/TrEMBL
	A0A8I3NUL2_CANLF	UniProtKB/TrEMBL
	A0A8I3NVI8_CANLF	UniProtKB/TrEMBL
	A0A8I3NVK8_CANLF	UniProtKB/TrEMBL
	A0A8I3P3M7_CANLF	UniProtKB/TrEMBL
	A0A8P0PCM6_CANLF	UniProtKB/TrEMBL
	A0A8P0SHP0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SZ35_CANLF	UniProtKB/TrEMBL
	FUCO_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE
	Q71UI1_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:41005	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-07-04	FUCA1	alpha-L-fucosidase 1		fucosidase, alpha-L- 1, tissue	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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