MIR18A (microRNA mir-18a) - Rat Genome Database

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Gene: MIR18A (microRNA mir-18a) Canis lupus familiaris
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Symbol: MIR18A
Name: microRNA mir-18a (Ensembl:microRNA 18a)
RGD ID: 12341122
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-18a; microRNA 18a
RGD Orthologs
Human
Mouse
Rat
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12242,478,138 - 42,478,229 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2242,478,138 - 42,478,229 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2242,333,826 - 42,333,917 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02242,879,387 - 42,879,478 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2242,879,387 - 42,879,478 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12242,561,860 - 42,561,951 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02242,616,239 - 42,616,330 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02242,617,302 - 42,617,393 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (ISO)
RISC complex  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:16381832   PMID:18215311  


Genomics

Comparative Map Data
MIR18A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12242,478,138 - 42,478,229 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2242,478,138 - 42,478,229 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2242,333,826 - 42,333,917 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02242,879,387 - 42,879,478 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2242,879,387 - 42,879,478 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12242,561,860 - 42,561,951 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02242,616,239 - 42,616,330 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02242,617,302 - 42,617,393 (+)NCBIUU_Cfam_GSD_1.0
MIR18A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381391,350,751 - 91,350,821 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1391,350,751 - 91,350,821 (+)EnsemblGRCh38hg38GRCh38
GRCh371392,003,005 - 92,003,075 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361390,801,005 - 90,801,075 (+)NCBINCBI36Build 36hg18NCBI36
Celera1372,849,976 - 72,850,046 (+)NCBICelera
Cytogenetic Map13q31.3NCBI
HuRef1372,598,840 - 72,598,910 (+)NCBIHuRef
CHM1_11391,971,645 - 91,971,715 (+)NCBICHM1_1
T2T-CHM13v2.01390,553,327 - 90,553,397 (+)NCBIT2T-CHM13v2.0
Mir18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914115,281,283 - 115,281,378 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14115,281,283 - 115,281,378 (+)EnsemblGRCm39 Ensembl
GRCm3814115,043,851 - 115,043,946 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14115,043,851 - 115,043,946 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714115,443,073 - 115,443,168 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera14113,634,419 - 113,634,514 (+)NCBICelera
Cytogenetic Map14E4NCBI
cM Map1459.4NCBI
Mir18a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81598,587,984 - 98,588,079 (+)NCBIGRCr8
mRatBN7.21592,180,765 - 92,180,860 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1592,180,765 - 92,180,860 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1596,087,554 - 96,087,649 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01597,220,420 - 97,220,515 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01594,127,826 - 94,127,921 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015100,180,015 - 100,180,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15100,180,015 - 100,180,110 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015103,641,038 - 103,641,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1591,045,445 - 91,045,540 (+)NCBICelera
Cytogenetic Map15q23NCBI
MIR18A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1160,734,791 - 60,734,882 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11160,734,791 - 60,734,882 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21166,610,195 - 66,610,286 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000032746
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2242,478,138 - 42,478,229 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845012454
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2242,879,387 - 42,879,478 (+)Ensembl
RefSeq Acc Id: NR_049418
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12242,478,138 - 42,478,229 (+)NCBI
Dog10K_Boxer_Tasha2242,333,826 - 42,333,917 (+)NCBI
ROS_Cfam_1.02242,879,387 - 42,879,478 (+)NCBI
UMICH_Zoey_3.12242,561,860 - 42,561,951 (+)NCBI
UNSW_CanFamBas_1.02242,616,239 - 42,616,330 (+)NCBI
UU_Cfam_GSD_1.02242,617,302 - 42,617,393 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020639 Ensembl
  ENSCAFG00845007015 Ensembl, ENTREZGENE
Ensembl Transcript ENSCAFT00845012454 ENTREZGENE
miRBase MI0010324 ENTREZGENE
NCBI Gene MIR18A ENTREZGENE
RNAcentral URS00000A05D9 RNACentral
  URS000075A5E6 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR18A  microRNA mir-18a    microRNA 18a  Symbol and/or name change 5135510 APPROVED