EFCAB9 (EF-hand calcium binding domain 9) - Rat Genome Database

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Gene: EFCAB9 (EF-hand calcium binding domain 9) Canis lupus familiaris
Analyze
Symbol: EFCAB9
Name: EF-hand calcium binding domain 9
RGD ID: 12338547
Description: ENCODES a protein that exhibits calcium ion binding (inferred); calcium ion sensor activity (inferred); INVOLVED IN flagellated sperm motility (inferred); sperm capacitation (inferred); spermatogenesis (inferred); FOUND IN CatSper complex (inferred); cytoplasm (inferred); sperm principal piece (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: EF-hand calcium-binding domain-containing protein 9
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1440,055,027 - 40,076,789 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl440,055,159 - 40,076,729 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha440,001,892 - 40,023,564 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0440,428,550 - 40,450,227 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl440,444,434 - 40,450,501 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1440,243,974 - 40,265,642 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0440,433,762 - 40,455,436 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0440,943,872 - 40,965,549 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EFCAB9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1440,055,027 - 40,076,789 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl440,055,159 - 40,076,729 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha440,001,892 - 40,023,564 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0440,428,550 - 40,450,227 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl440,444,434 - 40,450,501 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1440,243,974 - 40,265,642 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0440,433,762 - 40,455,436 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0440,943,872 - 40,965,549 (-)NCBIUU_Cfam_GSD_1.0
EFCAB9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385172,194,172 - 172,203,454 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5172,194,172 - 172,203,454 (+)EnsemblGRCh38hg38GRCh38
GRCh375171,621,176 - 171,630,458 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365171,553,782 - 171,570,743 (+)NCBINCBI36Build 36hg18NCBI36
Celera5167,653,587 - 167,662,872 (+)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5166,716,995 - 166,726,283 (+)NCBIHuRef
CHM1_15171,053,835 - 171,063,704 (+)NCBICHM1_1
T2T-CHM13v2.05172,734,472 - 172,743,747 (+)NCBIT2T-CHM13v2.0
Efcab9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,472,733 - 32,483,144 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,472,751 - 32,482,081 (-)EnsemblGRCm39 Ensembl
GRCm381132,522,733 - 32,533,240 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,522,751 - 32,532,081 (-)EnsemblGRCm38mm10GRCm38
MGSCv371132,422,733 - 32,427,574 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,422,751 - 32,427,579 (-)NCBIMGSCv36mm8
Celera1134,942,118 - 34,946,959 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1118.97NCBI
Efcab9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81017,611,408 - 17,616,566 (-)NCBIGRCr8
mRatBN7.21017,107,123 - 17,112,282 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,107,123 - 17,112,289 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1021,852,847 - 21,857,904 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,341,450 - 21,346,507 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01016,832,035 - 16,837,089 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01017,399,291 - 17,406,915 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1017,407,979 - 17,415,251 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01017,291,887 - 17,293,606 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41017,367,983 - 17,373,610 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1016,753,816 - 16,758,829 (-)NCBICelera
Cytogenetic Map10q12NCBI
Efcab9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540824,988,212 - 24,993,963 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540824,987,401 - 24,993,284 (+)NCBIChiLan1.0ChiLan1.0
EFCAB9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24167,333,910 - 167,359,342 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15165,473,450 - 165,483,200 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05167,545,205 - 167,554,563 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15174,461,056 - 174,470,489 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5174,461,056 - 174,470,489 (+)Ensemblpanpan1.1panPan2
Efcab9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721394,359,430 - 94,364,093 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366093,082,264 - 3,086,721 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366093,082,136 - 3,086,721 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EFCAB9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1651,987,768 - 52,007,563 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11651,987,090 - 51,996,019 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21656,427,488 - 56,437,225 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EFCAB9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12374,360,052 - 74,369,105 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2374,360,551 - 74,368,822 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660344,253,617 - 4,263,104 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Efcab9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473317,813,429 - 17,818,512 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473317,813,381 - 17,818,562 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EFCAB9
141 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 8
Low 10 2 6 8 9 4
Below cutoff 5 5 10 4 4 4 6 4 1 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005619207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022417697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038473677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038534758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038599058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038663362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_536430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000026640   ⟹   ENSCAFP00000024746
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl440,070,995 - 40,076,729 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000092028   ⟹   ENSCAFP00000055906
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl440,055,159 - 40,076,729 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845002079   ⟹   ENSCAFP00845001628
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl440,444,434 - 40,450,501 (-)Ensembl
RefSeq Acc Id: XM_005619207   ⟹   XP_005619264
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1440,070,988 - 40,076,624 (-)NCBI
Dog10K_Boxer_Tasha440,017,777 - 40,023,403 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022417697   ⟹   XP_022273405
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1440,055,027 - 40,076,789 (-)NCBI
Dog10K_Boxer_Tasha440,001,892 - 40,023,564 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038473675   ⟹   XP_038329603
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1440,259,856 - 40,265,641 (-)NCBI
RefSeq Acc Id: XM_038473676   ⟹   XP_038329604
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1440,243,974 - 40,265,642 (-)NCBI
RefSeq Acc Id: XM_038473677   ⟹   XP_038329605
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1440,259,856 - 40,265,481 (-)NCBI
RefSeq Acc Id: XM_038534756   ⟹   XP_038390684
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0440,959,756 - 40,965,548 (-)NCBI
RefSeq Acc Id: XM_038534757   ⟹   XP_038390685
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0440,943,872 - 40,965,549 (-)NCBI
RefSeq Acc Id: XM_038534758   ⟹   XP_038390686
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0440,959,756 - 40,965,388 (-)NCBI
RefSeq Acc Id: XM_038599056   ⟹   XP_038454984
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0440,449,648 - 40,455,435 (-)NCBI
RefSeq Acc Id: XM_038599057   ⟹   XP_038454985
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0440,433,762 - 40,455,436 (-)NCBI
RefSeq Acc Id: XM_038599058   ⟹   XP_038454986
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0440,449,648 - 40,455,275 (-)NCBI
RefSeq Acc Id: XM_038663360   ⟹   XP_038519288
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0440,444,439 - 40,450,226 (-)NCBI
RefSeq Acc Id: XM_038663361   ⟹   XP_038519289
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0440,428,550 - 40,450,227 (-)NCBI
RefSeq Acc Id: XM_038663362   ⟹   XP_038519290
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0440,444,439 - 40,450,066 (-)NCBI
RefSeq Acc Id: XM_536430   ⟹   XP_536430
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1440,070,993 - 40,076,788 (-)NCBI
Dog10K_Boxer_Tasha440,017,777 - 40,023,563 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_536430   ⟸   XM_536430
- Peptide Label: isoform X1
- UniProtKB: A0A8I3MY78 (UniProtKB/TrEMBL),   A0A8P0SKW2 (UniProtKB/TrEMBL),   A0A8C0PLH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005619264   ⟸   XM_005619207
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_022273405   ⟸   XM_022417697
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000055906   ⟸   ENSCAFT00000092028
RefSeq Acc Id: ENSCAFP00000024746   ⟸   ENSCAFT00000026640
RefSeq Acc Id: XP_038329604   ⟸   XM_038473676
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038329603   ⟸   XM_038473675
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038329605   ⟸   XM_038473677
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038454985   ⟸   XM_038599057
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038454984   ⟸   XM_038599056
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038454986   ⟸   XM_038599058
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038519289   ⟸   XM_038663361
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038519288   ⟸   XM_038663360
- Peptide Label: isoform X1
- UniProtKB: A0A8I3MY78 (UniProtKB/TrEMBL),   A0A8P0SKW2 (UniProtKB/TrEMBL),   A0A8C0PLH7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038519290   ⟸   XM_038663362
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038390685   ⟸   XM_038534757
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038390684   ⟸   XM_038534756
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PLH7 (UniProtKB/TrEMBL),   A0A8I3MY78 (UniProtKB/TrEMBL),   A0A8P0SKW2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038390686   ⟸   XM_038534758
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCAFP00845001628   ⟸   ENSCAFT00845002079
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016830 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030001474 UniProtKB/TrEMBL
  ENSCAFG00040000584 UniProtKB/TrEMBL
  ENSCAFG00845001213 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026640.5 UniProtKB/TrEMBL
  ENSCAFT00030002640.1 UniProtKB/TrEMBL
  ENSCAFT00040001031.1 UniProtKB/TrEMBL
  ENSCAFT00845002079 ENTREZGENE
  ENSCAFT00845002079.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  EFCAB9 UniProtKB/TrEMBL
NCBI Gene EFCAB9 ENTREZGENE
PANTHER EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9 UniProtKB/TrEMBL
  PTHR47065 UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
PROSITE EF_HAND_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A8C0PLH7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MY78 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SKW2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40219 ENTREZGENE