CYSLTR1 (cysteinyl leukotriene receptor 1) - Rat Genome Database

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Gene: CYSLTR1 (cysteinyl leukotriene receptor 1) Canis lupus familiaris
Analyze
Symbol: CYSLTR1
Name: cysteinyl leukotriene receptor 1
RGD ID: 12227133
Description: ENCODES a protein that exhibits leukotriene receptor activity (ortholog); INVOLVED IN calcium ion transport (ortholog); cell surface receptor signaling pathway (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN endothelin signaling pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); allergic asthma (ortholog); allergic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X60,462,290 - 60,513,155 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX60,463,526 - 60,464,548 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX51,475,377 - 51,526,196 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X61,701,015 - 61,766,649 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX61,701,032 - 61,766,592 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X59,407,128 - 59,457,919 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X61,017,129 - 61,067,958 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X60,605,215 - 60,656,035 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CYSLTR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X60,462,290 - 60,513,155 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX60,463,526 - 60,464,548 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX51,475,377 - 51,526,196 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X61,701,015 - 61,766,649 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX61,701,032 - 61,766,592 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X59,407,128 - 59,457,919 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X61,017,129 - 61,067,958 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X60,605,215 - 60,656,035 (-)NCBIUU_Cfam_GSD_1.0
CYSLTR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X78,271,468 - 78,327,611 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX78,271,468 - 78,327,691 (-)EnsemblGRCh38hg38GRCh38
GRCh37X77,526,965 - 77,583,108 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X77,414,786 - 77,469,743 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X77,334,275 - 77,389,232NCBI
CeleraX77,768,935 - 77,823,895 (-)NCBICelera
Cytogenetic MapXq21.1NCBI
HuRefX71,107,425 - 71,162,464 (-)NCBIHuRef
CHM1_1X77,421,213 - 77,476,168 (-)NCBICHM1_1
T2T-CHM13v2.0X76,708,793 - 76,764,940 (-)NCBIT2T-CHM13v2.0
Cysltr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X105,617,952 - 105,647,329 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX105,617,952 - 105,647,285 (-)EnsemblGRCm39 Ensembl
GRCm38X106,576,509 - 106,603,679 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX106,574,346 - 106,603,679 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X103,771,856 - 103,798,801 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X102,779,236 - 102,806,181 (-)NCBIMGSCv36mm8
CeleraX93,425,096 - 93,451,782 (-)NCBICelera
Cytogenetic MapXDNCBI
cM MapX47.36NCBI
Cysltr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X75,734,281 - 75,762,873 (-)NCBIGRCr8
mRatBN7.2X71,661,421 - 71,690,012 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX71,663,821 - 71,690,121 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX73,181,064 - 73,182,083 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X76,680,942 - 76,681,961 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X74,236,459 - 74,237,478 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X77,671,028 - 77,700,491 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX77,674,150 - 77,700,269 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X77,868,476 - 77,895,363 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X94,802,078 - 94,803,097 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X94,875,510 - 94,876,530 (-)NCBI
CeleraX72,975,213 - 72,976,232 (-)NCBICelera
Cytogenetic MapXq22NCBI
Cysltr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555571,667,518 - 1,702,272 (-)NCBIChiLan1.0ChiLan1.0
CYSLTR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X77,810,414 - 77,868,764 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X77,813,609 - 77,872,375 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X67,412,410 - 67,469,366 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X77,523,188 - 77,579,350 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX77,524,455 - 77,525,468 (-)Ensemblpanpan1.1panPan2
Cysltr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X54,157,074 - 54,184,386 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936547479,261 - 504,757 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYSLTR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX62,380,780 - 62,456,689 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X62,380,778 - 62,407,736 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X71,478,976 - 71,505,912 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103232241
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X67,218,777 - 67,300,655 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX67,220,048 - 67,221,061 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236680982,664 - 5,209 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cysltr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248362,556,269 - 2,597,008 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CYSLTR1
474 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 4 8 3 6 3 6 4 7 6
Below cutoff 1 5 14 3 3 6 8 6 3

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003435590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005641524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022416178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022416180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038448997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038464503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038524969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038524970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038586538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000027376   ⟹   ENSCAFP00000037233
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX60,463,526 - 60,464,548 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845036890   ⟹   ENSCAFP00845028881
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX61,701,032 - 61,766,592 (-)Ensembl
RefSeq Acc Id: XM_005641524   ⟹   XP_005641581
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X60,462,290 - 60,513,155 (-)NCBI
Dog10K_Boxer_TashaX51,475,377 - 51,526,196 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038448996   ⟹   XP_038304924
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X61,701,015 - 61,766,649 (-)NCBI
RefSeq Acc Id: XM_038448997   ⟹   XP_038304925
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X61,701,015 - 61,766,649 (-)NCBI
RefSeq Acc Id: XM_038464503   ⟹   XP_038320431
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_TashaX51,475,377 - 51,526,196 (-)NCBI
RefSeq Acc Id: XM_038524969   ⟹   XP_038380897
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X59,407,128 - 59,457,919 (-)NCBI
RefSeq Acc Id: XM_038524970   ⟹   XP_038380898
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X59,407,128 - 59,457,919 (-)NCBI
RefSeq Acc Id: XM_038586537   ⟹   XP_038442465
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X60,605,215 - 60,656,035 (-)NCBI
RefSeq Acc Id: XM_038586538   ⟹   XP_038442466
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X60,605,215 - 60,656,035 (-)NCBI
RefSeq Acc Id: XM_038650954   ⟹   XP_038506882
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X61,017,129 - 61,067,958 (-)NCBI
RefSeq Acc Id: XM_038650955   ⟹   XP_038506883
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X61,017,129 - 61,067,958 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005641581   ⟸   XM_005641524
- UniProtKB: A0A8C0Z0K5 (UniProtKB/TrEMBL),   A0A8C0R7G1 (UniProtKB/TrEMBL),   A0A8I3PED5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000037233   ⟸   ENSCAFT00000027376
RefSeq Acc Id: XP_038380897   ⟸   XM_038524969
RefSeq Acc Id: XP_038380898   ⟸   XM_038524970
RefSeq Acc Id: XP_038506882   ⟸   XM_038650954
RefSeq Acc Id: XP_038506883   ⟸   XM_038650955
RefSeq Acc Id: XP_038304924   ⟸   XM_038448996
- UniProtKB: A0A8C0Z0K5 (UniProtKB/TrEMBL),   A0A8C0R7G1 (UniProtKB/TrEMBL),   A0A8I3PED5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038304925   ⟸   XM_038448997
- UniProtKB: A0A8C0Z0K5 (UniProtKB/TrEMBL),   A0A8C0R7G1 (UniProtKB/TrEMBL),   A0A8I3PED5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038320431   ⟸   XM_038464503
- UniProtKB: A0A8C0Z0K5 (UniProtKB/TrEMBL),   A0A8C0R7G1 (UniProtKB/TrEMBL),   A0A8I3PED5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442465   ⟸   XM_038586537
- UniProtKB: A0A8C0R7G1 (UniProtKB/TrEMBL),   A0A8C0Z0K5 (UniProtKB/TrEMBL),   A0A8I3PED5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038442466   ⟸   XM_038586538
- UniProtKB: A0A8C0R7G1 (UniProtKB/TrEMBL),   A0A8C0Z0K5 (UniProtKB/TrEMBL),   A0A8I3PED5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845028881   ⟸   ENSCAFT00845036890
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017282 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010191 UniProtKB/TrEMBL
  ENSCAFG00040017420 UniProtKB/TrEMBL
  ENSCAFG00845020915 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000027376.3 UniProtKB/TrEMBL
  ENSCAFT00030018840.1 UniProtKB/TrEMBL
  ENSCAFT00040032153.1 UniProtKB/TrEMBL
  ENSCAFT00845036890 ENTREZGENE
  ENSCAFT00845036890.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro CLT1_recept UniProtKB/TrEMBL
  Cyst_leuk_rcpt UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
KEGG Report cfa:100686426 UniProtKB/TrEMBL
NCBI Gene CYSLTR1 ENTREZGENE
PANTHER CYSTEINYL LEUKOTRIENE RECEPTOR 1 UniProtKB/TrEMBL
  PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS CYSLT1RECPTR UniProtKB/TrEMBL
  CYSLTRECPTR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0R7G1 ENTREZGENE
  A0A8C0Z0K5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PED5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:50295 ENTREZGENE