TOMM7 (translocase of outer mitochondrial membrane 7) - Rat Genome Database

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Gene: TOMM7 (translocase of outer mitochondrial membrane 7) Canis lupus familiaris
Analyze
Symbol: TOMM7
Name: translocase of outer mitochondrial membrane 7
RGD ID: 12198233
Description: INVOLVED IN positive regulation of mitophagy in response to mitochondrial depolarization (ortholog); regulation of protein stability (ortholog); PARTICIPATES IN beta-barrel pathway of mitochondrial protein import; carrier pathway of mitochondrial protein import; mitochondrial autophagy pathway; ASSOCIATED WITH GARG-MISHRA PROGEROID SYNDROME (ortholog); hypomyelinating leukodystrophy 5 (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN mitochondrial outer membrane (inferred); mitochondrial outer membrane translocase complex (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mitochondrial import receptor subunit TOM7 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11436,523,707 - 36,532,180 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1436,523,707 - 36,532,291 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1436,064,815 - 36,073,285 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01436,448,151 - 36,456,622 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1436,446,035 - 36,457,537 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11436,569,183 - 36,577,658 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01436,265,841 - 36,274,316 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01436,602,729 - 36,611,207 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TOMM7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11436,523,707 - 36,532,180 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1436,523,707 - 36,532,291 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1436,064,815 - 36,073,285 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01436,448,151 - 36,456,622 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1436,446,035 - 36,457,537 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11436,569,183 - 36,577,658 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01436,265,841 - 36,274,316 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01436,602,729 - 36,611,207 (-)NCBIUU_Cfam_GSD_1.0
TOMM7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38722,812,974 - 22,822,849 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl722,812,628 - 22,822,849 (-)EnsemblGRCh38hg38GRCh38
GRCh37722,852,593 - 22,862,468 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36722,818,776 - 22,828,946 (-)NCBINCBI36Build 36hg18NCBI36
Build 34722,625,493 - 22,635,661NCBI
Celera722,837,876 - 22,848,044 (-)NCBICelera
Cytogenetic Map7p15.3NCBI
HuRef722,735,367 - 22,745,588 (-)NCBIHuRef
CHM1_1722,853,157 - 22,863,376 (-)NCBICHM1_1
T2T-CHM13v2.0722,948,907 - 22,958,779 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2722,903,376 - 22,913,595 (-)NCBI
Tomm7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39524,043,942 - 24,049,143 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl524,043,942 - 24,049,159 (-)EnsemblGRCm39 Ensembl
GRCm38523,838,944 - 23,844,145 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl523,838,944 - 23,844,161 (-)EnsemblGRCm38mm10GRCm38
MGSCv37523,344,762 - 23,349,963 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36523,349,719 - 23,354,172 (-)NCBIMGSCv36mm8
Celera520,790,590 - 20,795,798 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map510.48NCBI
Tomm7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8412,197,503 - 12,204,344 (+)NCBIGRCr8
mRatBN7.2411,305,122 - 11,311,963 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl411,305,110 - 11,311,962 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx416,456,675 - 16,463,543 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0412,281,753 - 12,288,658 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0410,628,651 - 10,635,519 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.047,835,949 - 7,842,790 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl47,835,949 - 7,842,789 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.047,844,007 - 7,850,848 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.446,675,775 - 6,682,616 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera46,919,104 - 6,925,945 (+)NCBICelera
Cytogenetic Map4q11NCBI
Tomm7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541025,157,860 - 25,166,898 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541025,157,860 - 25,166,898 (-)NCBIChiLan1.0ChiLan1.0
TOMM7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2627,679,302 - 27,689,182 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1776,004,028 - 76,013,912 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0723,501,438 - 23,511,321 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1723,112,630 - 23,122,195 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl723,112,630 - 23,122,195 (-)Ensemblpanpan1.1panPan2
Tomm7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511880,819,056 - 80,825,218 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647830,666 - 37,062 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647830,787 - 36,952 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOMM7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl991,570,065 - 91,579,015 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1991,570,069 - 91,578,991 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29100,959,712 - 100,968,629 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TOMM7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12135,485,860 - 35,496,281 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2135,485,685 - 35,497,325 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604269,090,185 - 69,100,606 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tomm7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247397,853,621 - 7,864,757 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247397,854,226 - 7,863,387 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TOMM7
100 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 5 17 1 4 1 6 3 12 8 10 6
Low 1 5 5 2 5 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000050114   ⟹   ENSCAFP00000037774
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1436,523,707 - 36,532,291 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000074735   ⟹   ENSCAFP00000058963
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1436,523,707 - 36,531,561 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845015586   ⟹   ENSCAFP00845012111
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1436,446,035 - 36,457,537 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845015624   ⟹   ENSCAFP00845012145
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1436,448,151 - 36,456,007 (-)Ensembl
RefSeq Acc Id: XM_038494805   ⟹   XP_038350733
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11436,569,183 - 36,577,658 (-)NCBI
RefSeq Acc Id: XM_038557082   ⟹   XP_038413010
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01436,602,729 - 36,611,207 (-)NCBI
RefSeq Acc Id: XM_038621022   ⟹   XP_038476950
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01436,265,841 - 36,274,316 (-)NCBI
RefSeq Acc Id: XM_038686707   ⟹   XP_038542635
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01436,448,151 - 36,456,622 (-)NCBI
RefSeq Acc Id: XM_539468   ⟹   XP_539468
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11436,523,707 - 36,532,180 (-)NCBI
Dog10K_Boxer_Tasha1436,064,815 - 36,073,285 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_539468   ⟸   XM_539468
- UniProtKB: A0A8C0PNC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000037774   ⟸   ENSCAFT00000050114
RefSeq Acc Id: ENSCAFP00000058963   ⟸   ENSCAFT00000074735
RefSeq Acc Id: XP_038350733   ⟸   XM_038494805
RefSeq Acc Id: XP_038476950   ⟸   XM_038621022
RefSeq Acc Id: XP_038542635   ⟸   XM_038686707
- UniProtKB: A0A8C0PNC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038413010   ⟸   XM_038557082
- UniProtKB: A0A8C0PNC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845012111   ⟸   ENSCAFT00845015586
RefSeq Acc Id: ENSCAFP00845012145   ⟸   ENSCAFT00845015624


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031816 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030026223 UniProtKB/TrEMBL
  ENSCAFG00040006906 UniProtKB/TrEMBL
  ENSCAFG00845008876 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000074735.2 UniProtKB/TrEMBL
  ENSCAFT00000106568.1 UniProtKB/TrEMBL
  ENSCAFT00030048522.1 UniProtKB/TrEMBL
  ENSCAFT00030048523.1 UniProtKB/TrEMBL
  ENSCAFT00040012835.1 UniProtKB/TrEMBL
  ENSCAFT00040012844.1 UniProtKB/TrEMBL
  ENSCAFT00845015586.1 UniProtKB/TrEMBL
  ENSCAFT00845015624.1 UniProtKB/TrEMBL
InterPro Tom7 UniProtKB/TrEMBL
KEGG Report cfa:482351 UniProtKB/TrEMBL
NCBI Gene TOMM7 ENTREZGENE
PANTHER MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG UniProtKB/TrEMBL
  MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM7 HOMOLOG UniProtKB/TrEMBL
Pfam Tom7 UniProtKB/TrEMBL
UniProt A0A8C0PNC9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RUB1_CANLF UniProtKB/TrEMBL
  A0A8I3N0I5_CANLF UniProtKB/TrEMBL
  A0A8I3N668_CANLF UniProtKB/TrEMBL
  A0A8P0PJR9_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:54798 ENTREZGENE