FRMPD2 (FERM and PDZ domain containing 2) - Rat Genome Database

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Gene: FRMPD2 (FERM and PDZ domain containing 2) Canis lupus familiaris
Analyze
Symbol: FRMPD2
Name: FERM and PDZ domain containing 2
RGD ID: 12097704
Description: ENCODES a protein that exhibits 1-phosphatidylinositol binding (ortholog); INVOLVED IN bicellular tight junction assembly (ortholog); ASSOCIATED WITH Cockayne syndrome B (ortholog); megacolon (ortholog); schizophrenia (ortholog); FOUND IN basolateral plasma membrane (ortholog); bicellular tight junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FERM and PDZ domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.128196,839 - 309,998 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha28421,044 - 539,662 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.028365,830 - 485,905 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.128172,901 - 285,653 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.028214,130 - 326,655 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.028300,201 - 420,038 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
FRMPD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.128196,839 - 309,998 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha28421,044 - 539,662 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.028365,830 - 485,905 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.128172,901 - 285,653 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.028214,130 - 326,655 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.028300,201 - 420,038 (-)NCBIUU_Cfam_GSD_1.0
FRMPD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381048,156,559 - 48,274,895 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1048,153,088 - 48,274,696 (-)EnsemblGRCh38hg38GRCh38
GRCh371049,364,602 - 49,482,739 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361049,034,611 - 49,152,723 (-)NCBINCBI36Build 36hg18NCBI36
Build 341049,034,607 - 49,129,806NCBI
Celera1042,962,487 - 43,068,811 (-)NCBICelera
Cytogenetic Map10q11.22NCBI
HuRef1043,635,981 - 43,747,566 (-)NCBIHuRef
HuRef1043,629,288 - 43,630,117 (-)NCBIHuRef
CHM1_11049,646,437 - 49,764,818 (-)NCBICHM1_1
T2T-CHM13v2.01048,998,450 - 49,123,638 (-)NCBIT2T-CHM13v2.0
Frmpd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391433,193,475 - 33,297,226 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1433,193,653 - 33,297,226 (+)EnsemblGRCm39 Ensembl
GRCm381433,483,501 - 33,575,269 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1433,471,696 - 33,575,269 (+)EnsemblGRCm38mm10GRCm38
MGSCv371434,284,882 - 34,384,044 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361432,300,788 - 32,404,360 (+)NCBIMGSCv36mm8
Celera1429,752,836 - 29,825,439 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.46NCBI
Frmpd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8168,763,889 - 8,883,558 (+)NCBIGRCr8
mRatBN7.2168,757,642 - 8,877,307 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl168,757,705 - 8,877,303 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0169,745,171 - 9,879,490 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl169,772,688 - 9,847,444 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01611,793,571 - 11,832,623 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01611,698,696 - 11,750,655 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4169,068,307 - 9,141,670 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera166,330,578 - 6,450,050 (-)NCBICelera
Cytogenetic Map16p16NCBI
Frmpd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555561,732,134 - 1,837,060 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555561,732,140 - 1,847,956 (+)NCBIChiLan1.0ChiLan1.0
FRMPD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2860,415,130 - 60,542,431 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11060,423,765 - 60,547,732 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01045,968,125 - 46,094,690 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
Frmpd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721380,716,359 - 80,851,521 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367281,919,128 - 2,050,930 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367281,919,161 - 2,053,794 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRMPD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1488,864,884 - 88,966,188 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11488,847,972 - 88,966,206 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21496,575,803 - 96,625,004 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FRMPD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1943,520,355 - 43,650,045 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl943,544,323 - 43,644,831 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660483,290,194 - 3,421,723 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in FRMPD2
1208 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_038439738   ⟹   XP_038295666
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.028365,830 - 485,905 (-)NCBI
RefSeq Acc Id: XM_038460724   ⟹   XP_038316652
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha28421,044 - 539,662 (-)NCBI
RefSeq Acc Id: XM_038514360   ⟹   XP_038370288
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.128172,901 - 285,653 (-)NCBI
RefSeq Acc Id: XM_038578012   ⟹   XP_038433940
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.028300,201 - 420,038 (-)NCBI
RefSeq Acc Id: XM_038642172   ⟹   XP_038498100
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.028214,130 - 326,655 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038370288   ⟸   XM_038514360
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038498100   ⟸   XM_038642172
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038295666   ⟸   XM_038439738
- Peptide Label: isoform X1
- UniProtKB: A0A8I3P932 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038316652   ⟸   XM_038460724
- Peptide Label: isoform X1
- UniProtKB: A0A8P0PNA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038433940   ⟸   XM_038578012
- Peptide Label: isoform X1
- UniProtKB: A0A8I3P932 (UniProtKB/TrEMBL)
Protein Domains
FERM   KIND   PDZ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000053207 UniProtKB/TrEMBL
  ENSCAFG00845019027 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000096434.1 UniProtKB/TrEMBL
  ENSCAFT00845033610.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
  FERM_PH-like_C UniProtKB/TrEMBL
  KIND_dom UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene FRMPD2 ENTREZGENE
PANTHER NON-SPECIFIC PROTEIN-TYROSINE KINASE UniProtKB/TrEMBL
  TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13 UniProtKB/TrEMBL
Pfam FERM_C UniProtKB/TrEMBL
  FERM_M UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PRINTS BAND41 UniProtKB/TrEMBL
PROSITE FERM_3 UniProtKB/TrEMBL
  KIND UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
SMART B41 UniProtKB/TrEMBL
  FERM_C UniProtKB/TrEMBL
  KIND UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47031 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A8I3P932 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PNA6 ENTREZGENE, UniProtKB/TrEMBL