IVD (isovaleryl-CoA dehydrogenase)

Gene: IVD (isovaleryl-CoA dehydrogenase) Canis lupus familiaris

Analyze

Symbol:

IVD (Ensembl: KNSTRN)

Name:

isovaleryl-CoA dehydrogenase

RGD ID:

12059226

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); isovaleryl-CoA dehydrogenase activity (ortholog); INVOLVED IN branched-chain amino acid catabolic process (ortholog); fatty acid beta-oxidation using acyl-CoA dehydrogenase (ortholog); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH amino acid metabolic disorder (ortholog); Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrial membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

isovaleryl Coenzyme A dehydrogenase; isovaleryl-CoA dehydrogenase, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IVD (isovaleryl-CoA dehydrogenase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ivd (isovaleryl coenzyme A dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ivd (isovaleryl-CoA dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ivd (isovaleryl-CoA dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IVD (isovaleryl-CoA dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ivd (isovaleryl-CoA dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IVD (isovaleryl-CoA dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IVD (isovaleryl-CoA dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	7,584,122 - 7,594,599 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	7,584,086 - 7,594,150 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	7,637,893 - 7,648,417 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	7,709,948 - 7,720,478 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	7,688,665 - 7,720,482 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	7,634,265 - 7,644,784 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	7,740,300 - 7,750,859 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	7,869,140 - 7,879,708 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amino acid metabolic disorder (ISO)

Bloom syndrome (ISO)

colorectal cancer (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

isovaleric acidemia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

branched-chain amino acid catabolic process (ISO)

fatty acid beta-oxidation using acyl-CoA dehydrogenase (ISO)

L-leucine catabolic process (IEA)

Cellular Component

mitochondrial matrix (ISO)

mitochondrial membrane (ISO)

mitochondrion (IEA)

nucleoplasm (IEA)

Molecular Function

acyl-CoA dehydrogenase activity (IEA)

flavin adenine dinucleotide binding (IEA)

identical protein binding (ISO)

isovaleryl-CoA dehydrogenase activity (IEA,ISO)

oxidoreductase activity (IEA)

protein binding (ISO)

short-chain fatty acyl-CoA dehydrogenase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway (ISO)

3-hydroxyisobutyric aciduria pathway (ISO)

3-methylcrotonyl CoA carboxylase 1 deficiency pathway (ISO)

3-methylglutaconic aciduria type 1 pathway (ISO)

3-methylglutaconic aciduria type 3 pathway (ISO)

isobutyryl-CoA dehydrogenase deficiency pathway (ISO)

isovaleric acidemia pathway (ISO)

maple syrup urine disease pathway (ISO)

methylmalonate semialdehyde dehydrogenase deficiency pathway (ISO)

methylmalonic acidemia pathway (ISO)

propionic acidemia pathway (ISO)

valine, leucine and isoleucine degradation pathway (ISO)

valproic acid pharmacokinetics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

IVD
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	7,584,122 - 7,594,599 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	7,584,086 - 7,594,150 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	7,637,893 - 7,648,417 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	7,709,948 - 7,720,478 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	7,688,665 - 7,720,482 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	7,634,265 - 7,644,784 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	7,740,300 - 7,750,859 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	7,869,140 - 7,879,708 (+)	NCBI		UU_Cfam_GSD_1.0

IVD
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	40,405,795 - 40,435,947 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	40,405,485 - 40,435,947 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	40,697,996 - 40,728,146 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	38,484,978 - 38,498,355 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	38,484,977 - 38,498,355	NCBI
Celera	15	17,463,670 - 17,479,493 (+)	NCBI		Celera
Cytogenetic Map	15	q15.1	NCBI
HuRef	15	17,541,064 - 17,556,886 (+)	NCBI		HuRef
CHM1_1	15	40,817,565 - 40,833,386 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	38,212,996 - 38,243,333 (+)	NCBI		T2T-CHM13v2.0

Ivd
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	118,692,475 - 118,713,388 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	118,692,435 - 118,713,390 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	118,861,959 - 118,882,909 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	118,861,954 - 118,882,909 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	118,687,736 - 118,707,093 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	118,553,441 - 118,572,798 (+)	NCBI		MGSCv36	mm8
Celera	2	120,013,107 - 120,032,696 (+)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI
cM Map	2	59.64	NCBI

Ivd
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	126,305,584 - 126,326,016 (+)	NCBI		GRCr8
mRatBN7.2	3	105,851,710 - 105,872,144 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	105,851,683 - 105,872,575 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	109,524,766 - 109,545,235 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	118,120,320 - 118,140,785 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	115,780,686 - 115,801,150 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	110,669,355 - 110,689,789 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	110,669,312 - 110,690,173 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	117,207,292 - 117,227,726 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	105,374,429 - 105,394,861 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	105,270,846 - 105,291,661 (+)	NCBI
Celera	3	104,765,745 - 104,785,979 (+)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

Ivd
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	7,327,557 - 7,346,027 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	7,327,557 - 7,341,533 (+)	NCBI	ChiLan1.0	ChiLan1.0

IVD
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	29,642,102 - 29,672,428 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	33,793,458 - 33,823,800 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	19,342,283 - 19,372,465 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	37,596,455 - 37,626,708 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	37,596,688 - 37,609,902 (+)	Ensembl	panpan1.1		panPan2

Ivd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	86,023,008 - 86,036,677 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	3,871,148 - 3,885,241 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	3,871,152 - 3,883,521 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IVD
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	130,893,984 - 130,910,586 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	130,896,488 - 130,910,582 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	145,981,544 - 145,995,640 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IVD
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	42,592,387 - 42,605,931 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	42,589,709 - 42,606,199 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	98,364,384 - 98,377,989 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in IVD
99 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5	22	6	6	6	6	6	12	8	10	6
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003640038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038441973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038441974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038461427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038516464	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038516465	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038580055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038580056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038644331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038644332	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000014516 ⟹ ENSCAFP00000013428

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	30	7,584,086 - 7,594,121 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000086648 ⟹ ENSCAFP00000059467

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	30	7,584,086 - 7,594,150 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000092068 ⟹ ENSCAFP00000059531

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	30	7,584,113 - 7,594,121 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845049932 ⟹ ENSCAFP00845039156

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	30	7,688,665 - 7,720,482 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845050048 ⟹ ENSCAFP00845039242

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	30	7,688,665 - 7,698,808 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845050093 ⟹ ENSCAFP00845039278

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	30	7,688,665 - 7,698,808 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845050132 ⟹ ENSCAFP00845039306

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	30	7,688,665 - 7,698,763 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845050165 ⟹ ENSCAFP00845039332

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	30	7,709,938 - 7,720,482 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845050193 ⟹ ENSCAFP00845039353

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	30	7,709,983 - 7,720,482 (+)	Ensembl

RefSeq Acc Id:

XM_003640038 ⟹ XP_003640086

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	30	7,584,122 - 7,594,599 (+)	NCBI
Dog10K_Boxer_Tasha	30	7,637,937 - 7,648,417 (+)	NCBI

Sequence:

show sequence

ATGGCGACTTCGGCTTGGCTCCTGGGACGGCGCGCGGCGCGCTGGAGGCTGCGGGCGCCGCTCG
GCAGCCTGACGTCCCGGCGGGCCCACTCCCTCCTGCCCGTGGACGATGCGATCAACGGGCTAAG
CGCCGAGCAGAAGCAGCTTCGTCAGACCATGGCTAAGTTTCTTCAGGAGCACCTAGCCCCCCAG
GCCCAGGAGATTGATCACTTCAATGAATTCAAGAACCTTCGAGAGTTTTGGAAGCAGCTGGGAA
ACCTGGGTGTCTTAGGTATCACTGCCCCTGCTCAGTACGGCGGCTCCGGCCTCGGCTACTTGGA
ACAAGTGCTGGTGATGGAGGAGATCTCCCGAGTTTCTGCAGCAGTGGGGCTCAGCTATGGTGCT
CACTCCAACCTCTGCCTTAACCAAATTGTGCGCAATGGAAATGAGGCCCAGAAGGAAAAGTACC
TCCCCAAGCTGATCAGCGGTGAGTACATCGGAGCCCTGGCCATGAGTGAGCCCAATGCTGGCTC
TGATGTTGTCTCTATGAAACTGAAAGCAGAGAAGAAAGGTGATTACTACATCCTAAATGGAAAC
AAGTTTTGGATTACTAATGGCCCTGATGCTGACATCCTTATCATCTATGCTAAGACAGATCTGG
CTGTTGTGCCAGCCTCTCGTGGCATCACAGCCTTTATTGTGGAGAAGAATATGCCTGGCTTTAG
CACCTCCAAGAAGCTGGACAAACTGGGGATGAGGGGCTCTAACACCTGTGAGCTAATCTTTGAA
GACTGCAAGGTTCCTGCTGCCAACATCCTGGGCCATCTAAGTAAGGGCGTCTACGTGCTGATGA
GTGGGCTGGACCTGGAACGGCTCGTGCTGTCTGGTGGGCCCCTTGGGCTCATGCAGGCCGTCCT
CGACCACACCATTCCCTACCTACACACAAGGGAAGCCTTTGGCCAGAAGATCGGCCACTTCCAG
CTGATGCAGGGGAAGATGGCCGACATGTACACCCGCCTCATGGCGTGCCGGCAGTATGTCTACA
ACGTCGCCAAGGCCTGTGATCAAGGCCACTGCACTGCCAAGGACTGCGCGGGGGTGATTCTTTA
CTCAGCTGAGTGCGCCACACGGGTTGCCCTGGATGGCATTCAGTGCTTCGGTGCCAATGGCTAC
ATCAACGACTTTCCCATGGGCCGCTTTCTGCGAGATGCCAAGCTGTATGAGATTGGGGCTGGGA
CCAGTGAGGTGAGGCGACTGGTCATCGGCAGGGCCTTCAACGCAGACTTCCACTAACCCCAGGA
CCTTTCACCCCCTTTCTCAGCACCTAGAGGCCTTTCTTTGGGAGTAGAGATACAGCAGCCCTTC
TGCTGCCCAGCTGCACTTGTGTCAGCCCTTGGCCTCTGCATGAGGTTGAGGTCTCTACTACGGC
TGGCAAGTGCTGTGGGCCTCAGAGCCTGCCCCCCGAGATGCTGCAAGTTGAAGGCGGGCCTGGG
GGAAAGGGAGCAACACTTCCAGTCACAACTTCTGGTCTGAAGATACTGTAGGACATTAATGGGA
GTTGTGGTGCGTGGAGGGCCTACCTGAAAAGTGTTCCATGGGTTCAGATGAACTCAGCAAGGGA
TGCCTGGGTGGCTCAACAGTTGAGCGAGTATCTGCTTTCAGCTCAGGGCATGATCCCGGACTCC
CGGGATCGAGTCCCACATCGGGCACCCTGTGAGTAGCCTGCTTCTTCCTCTGCCAGTGTCTCTG
CCTCTCTCTCTGTATCTCTCATGAATAAATAAATACAATCTAAAAAAA

hide sequence

RefSeq Acc Id:

XM_038441973 ⟹ XP_038297901

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	30	7,709,992 - 7,720,478 (+)	NCBI

RefSeq Acc Id:

XM_038441974 ⟹ XP_038297902

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	30	7,709,948 - 7,720,000 (+)	NCBI

RefSeq Acc Id:

XM_038461427 ⟹ XP_038317355

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	30	7,637,893 - 7,647,939 (+)	NCBI

RefSeq Acc Id:

XM_038516464 ⟹ XP_038372392

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	30	7,634,309 - 7,644,784 (+)	NCBI

RefSeq Acc Id:

XM_038516465 ⟹ XP_038372393

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	30	7,634,265 - 7,644,306 (+)	NCBI

RefSeq Acc Id:

XM_038580055 ⟹ XP_038435983

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	30	7,869,184 - 7,879,708 (+)	NCBI

RefSeq Acc Id:

XM_038580056 ⟹ XP_038435984

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	30	7,869,140 - 7,879,230 (+)	NCBI

RefSeq Acc Id:

XM_038644331 ⟹ XP_038500259

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	30	7,740,344 - 7,750,859 (+)	NCBI

RefSeq Acc Id:

XM_038644332 ⟹ XP_038500260

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	30	7,740,300 - 7,750,381 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003640086	(Get FASTA)	NCBI Sequence Viewer
	XP_038297901	(Get FASTA)	NCBI Sequence Viewer
	XP_038297902	(Get FASTA)	NCBI Sequence Viewer
	XP_038317355	(Get FASTA)	NCBI Sequence Viewer
	XP_038372392	(Get FASTA)	NCBI Sequence Viewer
	XP_038372393	(Get FASTA)	NCBI Sequence Viewer
	XP_038435983	(Get FASTA)	NCBI Sequence Viewer
	XP_038435984	(Get FASTA)	NCBI Sequence Viewer
	XP_038500259	(Get FASTA)	NCBI Sequence Viewer
	XP_038500260	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000013428.5
	ENSCAFP00000059467.2
	ENSCAFP00000059531.1
	ENSCAFP00030038540.1
	ENSCAFP00030038560.1
	ENSCAFP00040041737.1
	ENSCAFP00040041744.1
	ENSCAFP00845039156.1
	ENSCAFP00845039332
	ENSCAFP00845039332.1
	ENSCAFP00845039353.1

RefSeq Acc Id:	XP_003640086 ⟸ XM_003640038
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JWB9 (UniProtKB/TrEMBL), A0A8C0PI17 (UniProtKB/TrEMBL), A0A8I3QGH5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MATSAWLLGRRAARWRLRAPLGSLTSRRAHSLLPVDDAINGLSAEQKQLRQTMAKFLQEHLAPQ AQEIDHFNEFKNLREFWKQLGNLGVLGITAPAQYGGSGLGYLEQVLVMEEISRVSAAVGLSYGA HSNLCLNQIVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGDYYILNGN KFWITNGPDADILIIYAKTDLAVVPASRGITAFIVEKNMPGFSTSKKLDKLGMRGSNTCELIFE DCKVPAANILGHLSKGVYVLMSGLDLERLVLSGGPLGLMQAVLDHTIPYLHTREAFGQKIGHFQ LMQGKMADMYTRLMACRQYVYNVAKACDQGHCTAKDCAGVILYSAECATRVALDGIQCFGANGY INDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH hide sequence

RefSeq Acc Id:

ENSCAFP00000013428 ⟸ ENSCAFT00000014516

RefSeq Acc Id:

ENSCAFP00000059467 ⟸ ENSCAFT00000086648

RefSeq Acc Id:

ENSCAFP00000059531 ⟸ ENSCAFT00000092068

RefSeq Acc Id:	XP_038372393 ⟸ XM_038516465
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038372392 ⟸ XM_038516464
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038500260 ⟸ XM_038644332
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038500259 ⟸ XM_038644331
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038297902 ⟸ XM_038441974
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0PI17 (UniProtKB/TrEMBL), A0A8I3QGH5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038297901 ⟸ XM_038441973
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JWB9 (UniProtKB/TrEMBL), A0A8C0PI17 (UniProtKB/TrEMBL), A0A8I3QGH5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038317355 ⟸ XM_038461427
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0PI17 (UniProtKB/TrEMBL), A0A8I3QGH5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038435984 ⟸ XM_038580056
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0PI17 (UniProtKB/TrEMBL), A0A8I3QGH5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038435983 ⟸ XM_038580055
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0JWB9 (UniProtKB/TrEMBL), A0A8C0PI17 (UniProtKB/TrEMBL), A0A8I3QGH5 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845039156 ⟸ ENSCAFT00845049932

RefSeq Acc Id:

ENSCAFP00845039353 ⟸ ENSCAFT00845050193

RefSeq Acc Id:

ENSCAFP00845039242 ⟸ ENSCAFT00845050048

RefSeq Acc Id:

ENSCAFP00845039278 ⟸ ENSCAFT00845050093

RefSeq Acc Id:

ENSCAFP00845039332 ⟸ ENSCAFT00845050165

RefSeq Acc Id:

ENSCAFP00845039306 ⟸ ENSCAFT00845050132

Protein Domains

Acyl-CoA dehydrogenase/oxidase C-terminal Acyl-CoA dehydrogenase/oxidase N-terminal Acyl-CoA oxidase/dehydrogenase middle

Promoters

RGD ID:

13688475

Promoter ID:

EPDNEW_C6543

Type:

initiation region

Name:

IVD_1

Description:

isovaleryl-CoA dehydrogenase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	30	7,584,088 - 7,584,148	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000009116	Ensembl
	ENSCAFG00000050619	UniProtKB/TrEMBL
	ENSCAFG00030023927	UniProtKB/TrEMBL
	ENSCAFG00040025596	UniProtKB/TrEMBL
	ENSCAFG00845028164	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000014516.5	UniProtKB/TrEMBL
	ENSCAFT00000086648.2	UniProtKB/TrEMBL
	ENSCAFT00000092068.2	UniProtKB/TrEMBL
	ENSCAFT00030044163.1	UniProtKB/TrEMBL
	ENSCAFT00030044186.1	UniProtKB/TrEMBL
	ENSCAFT00040047805.1	UniProtKB/TrEMBL
	ENSCAFT00040047812.1	UniProtKB/TrEMBL
	ENSCAFT00845049932.1	UniProtKB/TrEMBL
	ENSCAFT00845050165	ENTREZGENE
	ENSCAFT00845050165.1	UniProtKB/TrEMBL
	ENSCAFT00845050193.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.540.10	UniProtKB/TrEMBL
	2.40.110.10	UniProtKB/TrEMBL
	Butyryl-CoA Dehydrogenase, subunit A, domain 3	UniProtKB/TrEMBL
InterPro	Acyl-CoA_DH_CS	UniProtKB/TrEMBL
	Acyl-CoA_Oxase/DH_mid-dom	UniProtKB/TrEMBL
	Acyl-CoA_Oxase/DH_mid-dom_sf	UniProtKB/TrEMBL
	AcylCo_DH-like_C	UniProtKB/TrEMBL
	AcylCo_DH/oxidase_C	UniProtKB/TrEMBL
	AcylCoA_DH/ox_N	UniProtKB/TrEMBL
	AcylCoA_DH/ox_N_sf	UniProtKB/TrEMBL
	AcylCoA_DH/oxidase_NM_dom	UniProtKB/TrEMBL
	IVD	UniProtKB/TrEMBL
NCBI Gene	IVD	ENTREZGENE
PANTHER	ACYL-COA DEHYDROGENASE	UniProtKB/TrEMBL
	ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED	UniProtKB/TrEMBL
Pfam	Acyl-CoA_dh_1	UniProtKB/TrEMBL
	Acyl-CoA_dh_M	UniProtKB/TrEMBL
	Acyl-CoA_dh_N	UniProtKB/TrEMBL
PROSITE	ACYL_COA_DH_1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47203	UniProtKB/TrEMBL
	SSF56645	UniProtKB/TrEMBL
UniProt	A0A8C0JWB9	ENTREZGENE
	A0A8C0PG77_CANLF	UniProtKB/TrEMBL
	A0A8C0PI17	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3Q046_CANLF	UniProtKB/TrEMBL
	A0A8I3Q4T2_CANLF	UniProtKB/TrEMBL
	A0A8I3QGH5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SE91_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:54961	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

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