PLCD1 (phospholipase C delta 1) - Rat Genome Database

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Gene: PLCD1 (phospholipase C delta 1) Pan paniscus
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Symbol: PLCD1
Name: phospholipase C delta 1
RGD ID: 12013006
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent phospholipid binding (ortholog); enzyme binding (ortholog); INVOLVED IN angiogenesis (ortholog); G protein-coupled receptor signaling pathway (ortholog); labyrinthine layer blood vessel development (ortholog); PARTICIPATES IN G protein mediated signaling pathway; ASSOCIATED WITH alopecia (ortholog); Alzheimer's disease (ortholog); Brugada syndrome (ortholog); FOUND IN cytosol (ortholog); mitochondrial membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2237,961,770 - 37,984,008 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1337,966,534 - 37,988,753 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0337,906,359 - 37,928,564 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1338,189,496 - 38,211,784 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl338,189,496 - 38,206,886 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLCD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2237,961,770 - 37,984,008 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1337,966,534 - 37,988,753 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0337,906,359 - 37,928,564 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1338,189,496 - 38,211,784 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl338,189,496 - 38,206,886 (-)Ensemblpanpan1.1panPan2
PLCD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38338,007,496 - 38,029,642 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl338,007,496 - 38,029,642 (-)EnsemblGRCh38hg38GRCh38
GRCh37338,048,987 - 38,071,133 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36338,023,991 - 38,059,068 (-)NCBINCBI36Build 36hg18NCBI36
Build 34338,024,010 - 38,046,119NCBI
Celera337,983,370 - 38,005,535 (-)NCBICelera
Cytogenetic Map3p22.2NCBI
HuRef337,991,684 - 38,013,851 (-)NCBIHuRef
CHM1_1338,000,639 - 38,022,806 (-)NCBICHM1_1
T2T-CHM13v2.0338,011,677 - 38,033,823 (-)NCBIT2T-CHM13v2.0
Plcd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399118,900,595 - 118,922,570 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9118,900,595 - 118,922,570 (-)EnsemblGRCm39 Ensembl
GRCm389119,071,527 - 119,093,502 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,071,527 - 119,093,502 (-)EnsemblGRCm38mm10GRCm38
MGSCv379118,980,645 - 119,002,614 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369118,920,225 - 118,942,194 (-)NCBIMGSCv36mm8
Celera9119,539,423 - 119,561,381 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map971.32NCBI
Plcd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88127,672,955 - 127,695,939 (-)NCBIGRCr8
mRatBN7.28118,795,196 - 118,818,186 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8118,795,201 - 118,818,186 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8124,397,003 - 124,419,829 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08122,595,953 - 122,618,783 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08120,428,662 - 120,451,606 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08127,753,514 - 127,782,070 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8127,753,539 - 127,782,070 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08126,970,643 - 126,991,422 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,023,090 - 124,052,193 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18124,042,827 - 124,071,930 (-)NCBI
Celera8117,968,204 - 117,991,136 (-)NCBICelera
Cytogenetic Map8q32NCBI
Plcd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554214,856,366 - 4,880,309 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554214,856,366 - 4,880,309 (-)NCBIChiLan1.0ChiLan1.0
PLCD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1237,782,495 - 7,804,969 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl237,781,787 - 7,805,336 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha237,824,568 - 7,846,894 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0238,071,728 - 8,094,058 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl238,071,740 - 8,094,243 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1237,886,045 - 7,908,371 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0238,027,176 - 8,049,514 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0238,019,585 - 8,041,935 (-)NCBIUU_Cfam_GSD_1.0
Plcd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118194,225,831 - 194,248,765 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647327,364,389 - 27,387,412 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647327,364,404 - 27,387,337 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1322,851,584 - 22,872,992 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11322,851,581 - 22,872,950 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21324,826,459 - 24,847,853 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1151,372,874 - 1,395,475 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl151,373,234 - 1,395,711 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606310,103,145 - 10,125,488 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477320,108,004 - 20,130,630 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477320,108,383 - 20,130,630 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000029844   ⟹   ENSPPAP00000007461
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl338,189,496 - 38,206,886 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029850   ⟹   ENSPPAP00000007465
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl338,189,773 - 38,204,253 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029851   ⟹   ENSPPAP00000007466
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl338,189,773 - 38,202,616 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029852   ⟹   ENSPPAP00000007467
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl338,191,461 - 38,204,253 (-)Ensembl
RefSeq Acc Id: XM_003826105   ⟹   XP_003826153
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2237,961,770 - 37,984,008 (-)NCBI
NHGRI_mPanPan1337,966,534 - 37,988,753 (-)NCBI
Mhudiblu_PPA_v0337,906,359 - 37,928,564 (-)NCBI
PanPan1.1338,189,496 - 38,211,784 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003826106   ⟹   XP_003826154
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2237,961,770 - 37,979,316 (-)NCBI
NHGRI_mPanPan1337,966,534 - 37,984,002 (-)NCBI
Mhudiblu_PPA_v0337,906,359 - 37,923,696 (-)NCBI
PanPan1.1338,189,496 - 38,206,886 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063602260   ⟹   XP_063458330
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2237,961,770 - 37,979,206 (-)NCBI
RefSeq Acc Id: XM_063602261   ⟹   XP_063458331
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2237,961,770 - 37,983,974 (-)NCBI
RefSeq Acc Id: XP_003826153   ⟸   XM_003826105
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZX12 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003826154   ⟸   XM_003826106
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZR69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000007461   ⟸   ENSPPAT00000029844
RefSeq Acc Id: ENSPPAP00000007466   ⟸   ENSPPAT00000029851
RefSeq Acc Id: ENSPPAP00000007467   ⟸   ENSPPAT00000029852
RefSeq Acc Id: ENSPPAP00000007465   ⟸   ENSPPAT00000029850
RefSeq Acc Id: XP_063458331   ⟸   XM_063602261
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063458330   ⟸   XM_063602260
- Peptide Label: isoform X3
Protein Domains
C2   EF-hand   PH   PI-PLC Y-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000026688 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000029844.1 UniProtKB/TrEMBL
  ENSPPAT00000029850.1 UniProtKB/TrEMBL
  ENSPPAT00000029851.1 UniProtKB/TrEMBL
  ENSPPAT00000029852.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.20.20.190 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PI-PLC_fam UniProtKB/TrEMBL
  PLC-delta1 UniProtKB/TrEMBL
  PLC-delta1_EF UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
  PLC_EF-hand-like UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/TrEMBL
  PLipase_C_Pinositol-sp_Y UniProtKB/TrEMBL
NCBI Gene PLCD1 ENTREZGENE
PANTHER PTHR10336 UniProtKB/TrEMBL
  PTHR10336:SF80 UniProtKB/TrEMBL
Pfam EF-hand_like UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PH_12 UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/TrEMBL
PRINTS PHPHLIPASEC UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  PIPLC_X_DOMAIN UniProtKB/TrEMBL
  PIPLC_Y_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
  PLCXc UniProtKB/TrEMBL
  PLCYc UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF51695 UniProtKB/TrEMBL
UniProt A0A2R8ZR69 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZR73_PANPA UniProtKB/TrEMBL
  A0A2R8ZR74_PANPA UniProtKB/TrEMBL
  A0A2R8ZX12 ENTREZGENE, UniProtKB/TrEMBL