BRSK1 (BR serine/threonine kinase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: BRSK1 (BR serine/threonine kinase 1) Pan paniscus
Analyze
Symbol: BRSK1
Name: BR serine/threonine kinase 1
RGD ID: 12000263
Description: ENCODES a protein that exhibits molecular function inhibitor activity (ortholog); INVOLVED IN establishment of cell polarity (ortholog); G2/M transition of mitotic cell cycle (ortholog); neuron differentiation (ortholog); FOUND IN cholinergic synapse (ortholog); distal axon (ortholog); postsynaptic density (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase BRSK1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,421,716 - 61,450,169 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,150,814 - 63,179,322 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,326,538 - 52,355,060 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11961,021,479 - 61,046,190 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1961,021,493 - 61,045,659 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BRSK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22061,421,716 - 61,450,169 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11963,150,814 - 63,179,322 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01952,326,538 - 52,355,060 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11961,021,479 - 61,046,190 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1961,021,493 - 61,045,659 (+)Ensemblpanpan1.1panPan2
BRSK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381955,283,997 - 55,312,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1955,282,072 - 55,312,562 (+)EnsemblGRCh38hg38GRCh38
GRCh371955,795,365 - 55,823,930 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361960,487,346 - 60,515,742 (+)NCBINCBI36Build 36hg18NCBI36
Build 341960,487,345 - 60,515,713NCBI
Celera1952,836,546 - 52,864,920 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1952,118,294 - 52,145,956 (+)NCBIHuRef
CHM1_11955,789,481 - 55,817,759 (+)NCBICHM1_1
T2T-CHM13v2.01958,379,535 - 58,408,087 (+)NCBIT2T-CHM13v2.0
Brsk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3974,693,635 - 4,718,996 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl74,693,603 - 4,718,996 (+)EnsemblGRCm39 Ensembl
GRCm3874,690,636 - 4,715,999 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl74,690,604 - 4,715,997 (+)EnsemblGRCm38mm10GRCm38
MGSCv3774,642,530 - 4,667,599 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3674,294,015 - 4,319,084 (+)NCBIMGSCv36mm8
MGSCv3674,044,979 - 4,071,504 (+)NCBIMGSCv36mm8
Celera74,421,153 - 4,445,975 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map72.71NCBI
Brsk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,162,944 - 78,193,598 (-)NCBIGRCr8
mRatBN7.2169,134,166 - 69,159,947 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,134,565 - 69,160,365 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx174,479,595 - 74,504,981 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0183,043,896 - 83,069,282 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,196,377 - 76,221,930 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0172,701,281 - 72,727,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,701,610 - 72,727,112 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0175,808,536 - 75,834,327 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,851,020 - 67,876,360 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera167,964,521 - 67,990,006 (+)NCBICelera
Cytogenetic Map1q12NCBI
Brsk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955567924,734 - 943,701 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955567924,728 - 943,092 (-)NCBIChiLan1.0ChiLan1.0
BRSK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11102,367,050 - 102,384,942 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1102,367,581 - 102,385,466 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1102,423,618 - 102,441,538 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01103,020,112 - 103,038,041 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1103,020,112 - 103,038,435 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11102,657,351 - 102,675,041 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01102,369,126 - 102,386,822 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01103,132,673 - 103,150,595 (-)NCBIUU_Cfam_GSD_1.0
Brsk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093491,992,067 - 2,013,003 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936886546,222 - 570,521 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936886541,831 - 567,197 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRSK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl659,468,733 - 59,499,059 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1659,468,289 - 59,499,062 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2654,372,199 - 54,377,541 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BRSK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1647,888,813 - 47,915,019 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl647,888,920 - 47,917,920 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045520,043 - 548,751 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Brsk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248321,975,314 - 1,995,056 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248321,975,448 - 1,995,102 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000056795   ⟹   ENSPPAP00000033914
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1961,021,493 - 61,045,659 (+)Ensembl
RefSeq Acc Id: XM_034946835   ⟹   XP_034802726
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22061,421,716 - 61,450,169 (+)NCBI
NHGRI_mPanPan11963,150,814 - 63,179,322 (+)NCBI
Mhudiblu_PPA_v01952,326,538 - 52,355,060 (+)NCBI
RefSeq Acc Id: XM_034946836   ⟹   XP_034802727
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22061,425,168 - 61,450,169 (+)NCBI
NHGRI_mPanPan11963,154,266 - 63,179,322 (+)NCBI
Mhudiblu_PPA_v01952,329,989 - 52,355,060 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034802726 (Get FASTA)   NCBI Sequence Viewer  
  XP_034802727 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000033914.1
Reference Protein Sequences
RefSeq Acc Id: XP_034802726   ⟸   XM_034946835
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C5T8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034802727   ⟸   XM_034946836
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C5T8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000033914   ⟸   ENSPPAT00000056795
Protein Domains
Protein kinase   UBA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039809 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000056795.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro BRSK1_2-like_UBA UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
NCBI Gene BRSK1 ENTREZGENE
PANTHER MAP/MICROTUBULE AFFINITY-REGULATING KINASE UniProtKB/TrEMBL
  SERINE_THREONINE-PROTEIN KINASE BRSK1 ISOFORM X1-RELATED UniProtKB/TrEMBL
Pfam KA1_BRSK UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
  UBA_BRSK UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A2R9C5T8 ENTREZGENE, UniProtKB/TrEMBL