PSMD14 (proteasome 26S subunit, non-ATPase 14) - Rat Genome Database

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Gene: PSMD14 (proteasome 26S subunit, non-ATPase 14) Pan paniscus
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Symbol: PSMD14
Name: proteasome 26S subunit, non-ATPase 14
RGD ID: 11960234
Description: ENCODES a protein that exhibits endopeptidase activator activity (inferred); metal-dependent deubiquitinase activity (inferred); metallopeptidase activity (inferred); INVOLVED IN protein K63-linked deubiquitination (ortholog); response to ethanol (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ASSOCIATED WITH Alcoholic Liver Diseases (ortholog); autistic disorder (ortholog); Disease Progression (ortholog); FOUND IN cytosolic proteasome complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 26S proteasome non-ATPase regulatory subunit 14; proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21363,997,127 - 64,103,767 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B64,014,080 - 64,118,739 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B48,602,395 - 48,705,229 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B165,972,229 - 166,074,879 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B165,972,229 - 166,074,879 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PSMD14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21363,997,127 - 64,103,767 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B64,014,080 - 64,118,739 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B48,602,395 - 48,705,229 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B165,972,229 - 166,074,879 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B165,972,229 - 166,074,879 (+)Ensemblpanpan1.1panPan2
PSMD14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382161,308,425 - 161,411,717 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2161,308,425 - 161,411,717 (+)EnsemblGRCh38hg38GRCh38
GRCh372162,164,936 - 162,268,228 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362161,873,186 - 161,976,172 (+)NCBINCBI36Build 36hg18NCBI36
Build 342161,990,446 - 162,093,433NCBI
Celera2155,776,557 - 155,880,315 (+)NCBICelera
Cytogenetic Map2q24.2NCBI
HuRef2154,049,213 - 154,152,684 (+)NCBIHuRef
CHM1_12162,170,938 - 162,274,393 (+)NCBICHM1_1
T2T-CHM13v2.02161,766,719 - 161,870,044 (+)NCBIT2T-CHM13v2.0
Psmd14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39261,542,038 - 61,630,720 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl261,542,038 - 61,630,720 (+)EnsemblGRCm39 Ensembl
GRCm38261,711,694 - 61,800,376 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl261,711,694 - 61,800,376 (+)EnsemblGRCm38mm10GRCm38
MGSCv37261,549,751 - 61,638,433 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36261,512,608 - 61,601,215 (+)NCBIMGSCv36mm8
Celera263,413,313 - 63,502,325 (+)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map235.56NCBI
Psmd14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8366,662,933 - 66,755,666 (+)NCBIGRCr8
mRatBN7.2346,254,338 - 46,347,076 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl346,254,330 - 46,347,076 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx349,600,021 - 49,692,757 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0358,183,542 - 58,276,273 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0355,966,122 - 56,058,875 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0347,578,449 - 47,673,330 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl347,578,384 - 47,673,338 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0354,249,938 - 54,344,886 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4343,660,136 - 43,699,412 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera345,922,238 - 46,014,721 (+)NCBICelera
Cytogenetic Map3q21NCBI
Psmd14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544912,306,026 - 12,400,908 (-)NCBIChiLan1.0ChiLan1.0
PSMD14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1366,883,612 - 6,985,291 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl366,889,622 - 6,984,974 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha367,019,712 - 7,122,412 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0367,006,841 - 7,109,577 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl367,006,840 - 7,117,492 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1367,023,304 - 7,125,998 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0367,067,598 - 7,170,265 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0367,175,451 - 7,278,173 (+)NCBIUU_Cfam_GSD_1.0
Psmd14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303124,016,680 - 124,123,583 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646917,494,134 - 17,601,045 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646917,494,137 - 17,601,045 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSMD14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1568,162,532 - 68,208,883 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11568,107,379 - 68,208,884 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21575,585,422 - 75,707,658 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PSMD14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11046,703,876 - 46,814,938 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1046,704,098 - 46,815,132 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040152,727,806 - 152,837,708 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psmd14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247324,057,810 - 4,150,209 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247324,057,519 - 4,150,178 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000039671   ⟹   ENSPPAP00000016972
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B165,972,229 - 166,074,879 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000039677   ⟹   ENSPPAP00000016978
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B166,027,452 - 166,074,562 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000039682   ⟹   ENSPPAP00000016983
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B166,029,307 - 166,074,562 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000039683   ⟹   ENSPPAP00000016984
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B166,029,899 - 166,074,562 (+)Ensembl
RefSeq Acc Id: XM_003820943   ⟹   XP_003820991
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21363,997,127 - 64,103,767 (+)NCBI
NHGRI_mPanPan12B64,014,080 - 64,118,739 (+)NCBI
Mhudiblu_PPA_v02B48,602,395 - 48,705,229 (+)NCBI
PanPan1.12B165,972,229 - 166,074,879 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008974415   ⟹   XP_008972663
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21363,997,127 - 64,103,767 (+)NCBI
NHGRI_mPanPan12B64,016,331 - 64,118,739 (+)NCBI
Mhudiblu_PPA_v02B48,602,796 - 48,705,229 (+)NCBI
PanPan1.12B165,972,432 - 166,074,879 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034954380   ⟹   XP_034810271
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21363,997,127 - 64,103,767 (+)NCBI
NHGRI_mPanPan12B64,016,295 - 64,118,739 (+)NCBI
Mhudiblu_PPA_v02B48,602,793 - 48,705,229 (+)NCBI
RefSeq Acc Id: XM_063595201   ⟹   XP_063451271
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21364,038,753 - 64,103,767 (+)NCBI
RefSeq Acc Id: XP_003820991   ⟸   XM_003820943
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AHY8 (UniProtKB/TrEMBL),   A0A2R9AIV7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008972663   ⟸   XM_008974415
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AHY8 (UniProtKB/TrEMBL),   A0A2R9AIV7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034810271   ⟸   XM_034954380
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AIV7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000016984   ⟸   ENSPPAT00000039683
RefSeq Acc Id: ENSPPAP00000016983   ⟸   ENSPPAT00000039682
RefSeq Acc Id: ENSPPAP00000016978   ⟸   ENSPPAT00000039677
RefSeq Acc Id: ENSPPAP00000016972   ⟸   ENSPPAT00000039671
RefSeq Acc Id: XP_063451271   ⟸   XM_063595201
- Peptide Label: isoform X3
Protein Domains
MPN


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031549 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000039671.1 UniProtKB/TrEMBL
  ENSPPAT00000039677.1 UniProtKB/TrEMBL
  ENSPPAT00000039682.1 UniProtKB/TrEMBL
  ENSPPAT00000039683.1 UniProtKB/TrEMBL
Gene3D-CATH Cytidine Deaminase, domain 2 UniProtKB/TrEMBL
InterPro JAMM/MPN+_dom UniProtKB/TrEMBL
  MPN UniProtKB/TrEMBL
KEGG Report pps:100984914 UniProtKB/TrEMBL
NCBI Gene PSMD14 ENTREZGENE
PANTHER 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 14 UniProtKB/TrEMBL
  EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED UniProtKB/TrEMBL
Pfam JAB UniProtKB/TrEMBL
PROSITE MPN UniProtKB/TrEMBL
SMART JAB_MPN UniProtKB/TrEMBL
Superfamily-SCOP JAB1/MPN domain UniProtKB/TrEMBL
UniProt A0A2R9AHY8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AIV7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AIW2_PANPA UniProtKB/TrEMBL
  A0A2R9AQ38_PANPA UniProtKB/TrEMBL