WDR77 (WD repeat domain 77) - Rat Genome Database

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Gene: WDR77 (WD repeat domain 77) Pan paniscus
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Symbol: WDR77
Name: WD repeat domain 77
RGD ID: 11940571
Description: ENCODES a protein that exhibits methyl-CpG binding (inferred); nuclear receptor coactivator activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN epithelial cell proliferation involved in prostate gland development (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of epithelial cell proliferation involved in prostate gland development (ortholog); ASSOCIATED WITH Ovarian Neoplasms (ortholog); FOUND IN methylosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: methylosome protein 50; methylosome protein WDR77
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21115,578,345 - 115,587,572 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11114,727,466 - 114,745,648 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01114,101,570 - 114,110,634 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11126,236,409 - 126,245,444 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1126,236,409 - 126,249,996 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
WDR77
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21115,578,345 - 115,587,572 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11114,727,466 - 114,745,648 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01114,101,570 - 114,110,634 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11126,236,409 - 126,245,444 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1126,236,409 - 126,249,996 (+)Ensemblpanpan1.1panPan2
WDR77
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381111,439,890 - 111,449,256 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1111,439,890 - 111,449,256 (-)EnsemblGRCh38hg38GRCh38
GRCh371111,982,512 - 111,991,878 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361111,784,035 - 111,793,353 (-)NCBINCBI36Build 36hg18NCBI36
Celera1110,229,435 - 110,238,753 (-)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1109,853,961 - 109,863,279 (-)NCBIHuRef
CHM1_11112,097,521 - 112,106,839 (-)NCBICHM1_1
T2T-CHM13v2.01111,454,574 - 111,463,940 (-)NCBIT2T-CHM13v2.0
Wdr77
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393105,866,814 - 105,877,076 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3105,866,685 - 105,877,353 (+)EnsemblGRCm39 Ensembl
GRCm383105,959,498 - 105,969,760 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3105,959,369 - 105,970,037 (+)EnsemblGRCm38mm10GRCm38
MGSCv373105,762,416 - 105,772,678 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363106,087,554 - 106,097,816 (+)NCBIMGSCv36mm8
Celera3108,149,918 - 108,160,180 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map346.46NCBI
Wdr77
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82196,123,882 - 196,133,853 (+)NCBIGRCr8
mRatBN7.22193,435,465 - 193,445,534 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2193,435,468 - 193,445,520 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2201,030,033 - 201,040,004 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02198,925,620 - 198,935,589 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02193,742,587 - 193,752,556 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02208,577,292 - 208,587,263 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2208,420,309 - 208,587,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2208,420,206 - 208,586,356 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02227,998,508 - 228,008,479 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42201,206,860 - 201,216,573 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12201,169,461 - 201,178,632 (+)NCBI
Celera2186,138,007 - 186,147,978 (+)NCBICelera
Cytogenetic Map2q34NCBI
Wdr77
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543514,933,243 - 14,940,438 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543514,929,202 - 14,940,439 (-)NCBIChiLan1.0ChiLan1.0
LOC479902
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1640,626,219 - 40,634,521 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl640,624,886 - 40,635,200 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1763,468,522 - 63,484,623 (+)NCBIDog10K_Boxer_Tasha
Wdr77
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505817,357,155 - 17,368,364 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936690109,359 - 121,125 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936690112,337 - 120,478 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR77
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4108,907,200 - 108,922,144 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14108,907,192 - 108,915,594 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24119,090,107 - 119,098,520 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WDR77
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12022,162,605 - 22,171,495 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2022,162,692 - 22,172,171 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603836,307,661 - 36,316,687 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr77
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247727,158,530 - 7,167,042 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247727,158,530 - 7,167,034 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000054690   ⟹   ENSPPAP00000031825
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1126,236,409 - 126,245,444 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000054717   ⟹   ENSPPAP00000031852
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1126,236,548 - 126,249,996 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000054726   ⟹   ENSPPAP00000031861
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1126,236,548 - 126,244,489 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000054732   ⟹   ENSPPAP00000031867
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1126,236,548 - 126,244,489 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000054746   ⟹   ENSPPAP00000031881
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1126,236,548 - 126,244,489 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000054748   ⟹   ENSPPAP00000031883
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1126,242,248 - 126,244,489 (+)Ensembl
RefSeq Acc Id: XM_003810679   ⟹   XP_003810727
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21115,578,345 - 115,587,572 (+)NCBI
NHGRI_mPanPan11114,727,466 - 114,745,648 (+)NCBI
Mhudiblu_PPA_v01114,101,570 - 114,110,634 (-)NCBI
PanPan1.11126,236,409 - 126,245,444 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034933546   ⟹   XP_034789437
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21115,578,653 - 115,587,572 (+)NCBI
NHGRI_mPanPan11114,727,466 - 114,745,648 (+)NCBI
Mhudiblu_PPA_v01114,102,725 - 114,110,634 (-)NCBI
RefSeq Acc Id: XM_034933547   ⟹   XP_034789438
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21115,578,653 - 115,587,572 (+)NCBI
NHGRI_mPanPan11114,727,466 - 114,745,648 (+)NCBI
Mhudiblu_PPA_v01114,101,570 - 114,110,634 (-)NCBI
RefSeq Acc Id: XP_003810727   ⟸   XM_003810679
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BQX5 (UniProtKB/TrEMBL),   A0A2R9BQB4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034789438   ⟸   XM_034933547
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BQB4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034789437   ⟸   XM_034933546
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BQB8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000031825   ⟸   ENSPPAT00000054690
RefSeq Acc Id: ENSPPAP00000031861   ⟸   ENSPPAT00000054726
RefSeq Acc Id: ENSPPAP00000031852   ⟸   ENSPPAT00000054717
RefSeq Acc Id: ENSPPAP00000031867   ⟸   ENSPPAT00000054732
RefSeq Acc Id: ENSPPAP00000031881   ⟸   ENSPPAT00000054746
RefSeq Acc Id: ENSPPAP00000031883   ⟸   ENSPPAT00000054748


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038773 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054690.1 UniProtKB/TrEMBL
  ENSPPAT00000054717.1 UniProtKB/TrEMBL
  ENSPPAT00000054726.1 UniProtKB/TrEMBL
  ENSPPAT00000054732.1 UniProtKB/TrEMBL
  ENSPPAT00000054746.1 UniProtKB/TrEMBL
  ENSPPAT00000054748.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100978868 UniProtKB/TrEMBL
NCBI Gene WDR77 ENTREZGENE
PANTHER METHYLOSOME PROTEIN 50 UniProtKB/TrEMBL
  METHYLOSOME PROTEIN 50 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A2R9BQB4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BQB8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BQD2_PANPA UniProtKB/TrEMBL
  A0A2R9BQD6_PANPA UniProtKB/TrEMBL
  A0A2R9BQX5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BZF0_PANPA UniProtKB/TrEMBL