MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3) - Rat Genome Database

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Gene: MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3) Pan paniscus
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Symbol: MAPK8IP3
Name: mitogen-activated protein kinase 8 interacting protein 3
RGD ID: 11935877
Description: ENCODES a protein that exhibits mitogen-activated protein kinase kinase binding (ortholog); INVOLVED IN axon guidance (ortholog); axon regeneration (ortholog); forebrain development (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 4 (ortholog); Developmental Disabilities (ortholog); FOUND IN cell body (ortholog); perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C-Jun-amino-terminal kinase-interacting protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2181,972,062 - 2,036,951 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,753,961 - 5,818,396 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016327,995 - 392,691 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1161,777,038 - 1,822,716 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl161,759,171 - 1,821,246 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MAPK8IP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2181,972,062 - 2,036,951 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,753,961 - 5,818,396 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016327,995 - 392,691 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1161,777,038 - 1,822,716 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl161,759,171 - 1,821,246 (+)Ensemblpanpan1.1panPan2
MAPK8IP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,706,195 - 1,770,351 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl161,706,166 - 1,770,351 (+)EnsemblGRCh38hg38GRCh38
GRCh37161,756,196 - 1,820,352 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,696,222 - 1,760,319 (+)NCBINCBI36Build 36hg18NCBI36
Build 34161,696,221 - 1,760,318NCBI
Celera161,968,494 - 2,032,593 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef161,681,212 - 1,743,210 (+)NCBIHuRef
CHM1_1161,756,194 - 1,820,266 (+)NCBICHM1_1
T2T-CHM13v2.0161,722,043 - 1,786,181 (+)NCBIT2T-CHM13v2.0
Mapk8ip3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,116,480 - 25,155,951 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1725,111,127 - 25,155,942 (-)EnsemblGRCm39 Ensembl
GRCm381724,897,506 - 24,936,977 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,892,153 - 24,936,977 (-)EnsemblGRCm38mm10GRCm38
MGSCv371725,034,451 - 25,073,922 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,625,154 - 24,664,568 (-)NCBIMGSCv36mm8
Celera1725,424,206 - 25,463,501 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.53NCBI
Mapk8ip3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,422,936 - 14,463,387 (-)NCBIGRCr8
mRatBN7.21013,918,417 - 13,958,335 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,918,400 - 13,958,273 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,666,921 - 18,705,192 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,155,781 - 18,194,055 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,654,998 - 13,693,274 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,259,394 - 14,299,276 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,260,787 - 14,299,167 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01014,075,410 - 14,115,275 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,147,895 - 14,186,277 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1013,599,018 - 13,637,404 (-)NCBICelera
Cytogenetic Map10q12NCBI
Mapk8ip3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,498,909 - 15,545,298 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,498,909 - 15,545,298 (-)NCBIChiLan1.0ChiLan1.0
MAPK8IP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,132,746 - 39,179,427 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,133,965 - 39,179,505 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,371,384 - 40,417,498 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,448,926 - 39,495,054 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,448,928 - 39,494,994 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1639,125,612 - 39,172,242 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,098,192 - 39,144,487 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,576,641 - 39,622,760 (-)NCBIUU_Cfam_GSD_1.0
Mapk8ip3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,446,068 - 104,486,444 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366942,222,996 - 2,263,390 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366942,223,020 - 2,263,388 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAPK8IP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,196,875 - 40,241,291 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1340,196,873 - 40,241,453 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,660,821 - 41,705,647 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAPK8IP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,616,672 - 1,679,350 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl51,616,668 - 1,677,721 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606829,406,891 - 29,469,206 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mapk8ip3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913481,207 - 529,070 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624913481,236 - 529,083 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000046420   ⟹   ENSPPAP00000023595
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl161,759,171 - 1,821,246 (+)Ensembl
RefSeq Acc Id: XM_063598204   ⟹   XP_063454274
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2181,972,062 - 2,036,951 (+)NCBI
RefSeq Acc Id: XM_063598205   ⟹   XP_063454275
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2181,972,062 - 2,036,951 (+)NCBI
RefSeq Acc Id: XM_063598206   ⟹   XP_063454276
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2181,972,062 - 2,036,951 (+)NCBI
RefSeq Acc Id: XM_063598207   ⟹   XP_063454277
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2181,972,062 - 2,036,951 (+)NCBI
RefSeq Acc Id: XM_063598208   ⟹   XP_063454278
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2181,972,062 - 2,036,951 (+)NCBI
RefSeq Acc Id: XM_063598209   ⟹   XP_063454279
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2181,972,062 - 2,036,951 (+)NCBI
RefSeq Acc Id: XM_063598210   ⟹   XP_063454280
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2181,972,062 - 2,036,951 (+)NCBI
RefSeq Acc Id: XM_063598211   ⟹   XP_063454281
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2182,008,736 - 2,036,951 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000023595   ⟸   ENSPPAT00000046420
RefSeq Acc Id: XP_063454277   ⟸   XM_063598207
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063454276   ⟸   XM_063598206
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063454280   ⟸   XM_063598210
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063454274   ⟸   XM_063598204
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063454278   ⟸   XM_063598208
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063454275   ⟸   XM_063598205
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063454279   ⟸   XM_063598209
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063454281   ⟸   XM_063598211
- Peptide Label: isoform X8
Protein Domains
RH1   RH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034790 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046420.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.1770 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
  arf6 gtpase in complex with a specific effector, jip4 UniProtKB/TrEMBL
InterPro JIP3/JIP4 UniProtKB/TrEMBL
  JIP_LZII UniProtKB/TrEMBL
  JNK/Rab-associated_protein-1_N UniProtKB/TrEMBL
  RH1 UniProtKB/TrEMBL
  RH2 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene MAPK8IP3 ENTREZGENE
PANTHER C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 3 UniProtKB/TrEMBL
  PTHR13886 UniProtKB/TrEMBL
Pfam JIP_LZII UniProtKB/TrEMBL
  Jnk-SapK_ap_N UniProtKB/TrEMBL
  WD40_2 UniProtKB/TrEMBL
PROSITE RH1 UniProtKB/TrEMBL
  RH2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A2R9B1W9_PANPA UniProtKB/TrEMBL