GDF10 (growth differentiation factor 10) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: GDF10 (growth differentiation factor 10) Pan paniscus
Analyze
Symbol: GDF10
Name: growth differentiation factor 10
RGD ID: 11935413
Description: ENCODES a protein that exhibits cytokine activity (inferred); growth factor activity (inferred); INVOLVED IN cerebellum development (ortholog); osteoblast differentiation (ortholog); ovulation cycle (ortholog); ASSOCIATED WITH Arterial Occlusive Diseases (ortholog); Breast Neoplasms (ortholog); genetic disease (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: growth/differentiation factor 10
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2859,997,778 - 60,011,111 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11060,003,095 - 60,016,428 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01046,498,600 - 46,511,933 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GDF10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2859,997,778 - 60,011,111 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11060,003,095 - 60,016,428 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01046,498,600 - 46,511,933 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GDF10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381047,300,197 - 47,313,577 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1047,300,197 - 47,313,577 (+)EnsemblGRCh38hg38GRCh38
GRCh371048,425,785 - 48,439,165 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361048,045,795 - 48,059,172 (-)NCBINCBI36Build 36hg18NCBI36
Build 341048,045,794 - 48,059,172NCBI
Celera1044,850,007 - 44,863,384 (-)NCBICelera
Cytogenetic Map10q11.22NCBI
HuRef1043,178,553 - 43,191,903 (-)NCBIHuRef
CHM1_11048,590,851 - 48,604,204 (-)NCBICHM1_1
T2T-CHM13v2.01048,191,293 - 48,204,673 (+)NCBIT2T-CHM13v2.0
Gdf10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391433,645,544 - 33,658,471 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1433,645,544 - 33,659,940 (+)EnsemblGRCm39 Ensembl
GRCm381433,923,587 - 33,936,514 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1433,923,587 - 33,937,983 (+)EnsemblGRCm38mm10GRCm38
MGSCv371434,736,773 - 34,748,471 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361432,752,679 - 32,764,377 (+)NCBIMGSCv36mm8
Celera1430,189,682 - 30,201,380 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.8NCBI
Gdf10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8169,243,434 - 9,256,788 (+)NCBIGRCr8
mRatBN7.2169,237,182 - 9,250,537 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,237,261 - 9,249,343 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx169,256,689 - 9,268,770 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01610,401,395 - 10,413,477 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0169,251,785 - 9,263,853 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01610,250,508 - 10,262,383 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1610,250,404 - 10,263,150 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0168,571,370 - 8,583,245 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4169,558,781 - 9,570,656 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1169,558,727 - 9,570,654 (+)NCBI
Celera165,961,266 - 5,973,147 (-)NCBICelera
Cytogenetic Map16p16NCBI
Gdf10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555562,185,121 - 2,196,502 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555562,185,121 - 2,195,150 (+)NCBIChiLan1.0ChiLan1.0
GDF10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1435,008,204 - 35,017,476 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl435,008,983 - 35,018,166 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha434,972,559 - 34,981,749 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0435,368,659 - 35,377,901 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl435,368,660 - 35,378,771 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1435,200,361 - 35,209,442 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0435,381,596 - 35,390,831 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0435,889,219 - 35,898,460 (-)NCBIUU_Cfam_GSD_1.0
Gdf10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721381,283,121 - 81,297,318 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365547,292,767 - 7,307,009 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365547,292,805 - 7,307,001 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GDF10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1488,522,948 - 88,534,709 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11488,522,956 - 88,534,719 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21496,148,673 - 96,160,426 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GDF10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1944,066,979 - 44,080,319 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl944,067,469 - 44,079,522 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660483,837,123 - 3,850,490 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003809047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_003809047   ⟹   XP_003809095
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2859,997,778 - 60,011,111 (-)NCBI
NHGRI_mPanPan11060,003,095 - 60,016,428 (-)NCBI
Mhudiblu_PPA_v01046,498,600 - 46,511,933 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003809095 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000037149
  ENSPPAP00000037149.1
Reference Protein Sequences
RefSeq Acc Id: XP_003809095   ⟸   XM_003809047
- UniProtKB: A0A2R9C5P7 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
TGF-beta family profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041322 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060047.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
InterPro BMP3/BMP3B UniProtKB/TrEMBL
  Cystine-knot_cytokine UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
KEGG Report pps:100984274 UniProtKB/TrEMBL
NCBI Gene GDF10 ENTREZGENE
PANTHER GROWTH/DIFFERENTIATION FACTOR 10 UniProtKB/TrEMBL
  PTHR11848 UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
PIRSF BMP3/GDF10 UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A2R9C5P7 ENTREZGENE, UniProtKB/TrEMBL