CPXM2 (carboxypeptidase X, M14 family member 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: CPXM2 (carboxypeptidase X, M14 family member 2) Pan paniscus
Analyze
Symbol: CPXM2
Name: carboxypeptidase X, M14 family member 2
RGD ID: 11881539
Description: ENCODES a protein that exhibits carboxypeptidase activity (ortholog); INVOLVED IN proteolysis (ortholog); ASSOCIATED WITH breast ductal carcinoma (ortholog); invasive ductal carcinoma (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inactive carboxypeptidase-like protein X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28135,588,322 - 135,735,921 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110135,593,728 - 135,741,271 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010120,302,984 - 120,449,022 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110124,576,161 - 124,721,359 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10124,576,161 - 124,721,359 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CPXM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28135,588,322 - 135,735,921 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110135,593,728 - 135,741,271 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010120,302,984 - 120,449,022 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110124,576,161 - 124,721,359 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10124,576,161 - 124,721,359 (-)Ensemblpanpan1.1panPan2
CPXM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810123,745,639 - 123,944,104 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10123,706,207 - 123,940,267 (-)EnsemblGRCh38hg38GRCh38
GRCh3710125,505,155 - 125,651,323 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610125,495,142 - 125,641,490 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410125,495,141 - 125,641,490NCBI
Celera10119,210,810 - 119,357,101 (-)NCBICelera
Cytogenetic Map10q26.13NCBI
HuRef10119,120,570 - 119,266,868 (-)NCBIHuRef
CHM1_110125,787,211 - 125,933,512 (-)NCBICHM1_1
T2T-CHM13v2.010124,622,492 - 124,821,277 (-)NCBIT2T-CHM13v2.0
Cpxm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397131,634,416 - 131,756,483 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7131,634,416 - 131,756,468 (-)EnsemblGRCm39 Ensembl
GRCm387132,032,687 - 132,154,765 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7132,032,687 - 132,154,739 (-)EnsemblGRCm38mm10GRCm38
MGSCv377139,234,493 - 139,346,424 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367131,881,159 - 131,993,082 (-)NCBIMGSCv36mm8
Celera7131,849,272 - 131,959,301 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map775.6NCBI
Cpxm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,266,930 - 196,377,350 (-)NCBIGRCr8
mRatBN7.21186,836,797 - 186,947,222 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1186,836,797 - 186,947,220 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1195,186,954 - 195,297,381 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01202,365,897 - 202,476,322 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01195,039,012 - 195,149,430 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01204,048,785 - 204,161,090 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1204,048,785 - 204,087,001 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01211,049,000 - 211,158,115 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41191,510,790 - 191,624,219 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11191,661,676 - 191,773,964 (-)NCBI
Celera1184,585,401 - 184,694,851 (-)NCBICelera
Cytogenetic Map1q41NCBI
Cpxm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554771,840,606 - 1,975,531 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554771,840,642 - 1,975,531 (-)NCBIChiLan1.0ChiLan1.0
CPXM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12833,219,823 - 33,380,852 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2833,220,890 - 33,467,746 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2833,284,486 - 33,412,252 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02833,776,621 - 33,904,851 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2833,776,640 - 34,059,105 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12833,333,240 - 33,461,276 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02833,325,593 - 33,454,253 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02833,575,878 - 33,705,412 (-)NCBIUU_Cfam_GSD_1.0
Cpxm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721313,225,717 - 13,311,170 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648612,251,199 - 12,345,542 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648612,250,128 - 12,335,578 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPXM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14133,246,526 - 133,376,489 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114133,246,521 - 133,376,378 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214144,880,552 - 145,027,128 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CPXM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19116,410,136 - 116,555,770 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9116,410,128 - 116,555,511 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604877,723,484 - 77,869,318 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cpxm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473723,156,028 - 23,299,522 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473723,156,008 - 23,299,312 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000052648   ⟹   ENSPPAP00000029797
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10124,576,161 - 124,721,359 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000052652   ⟹   ENSPPAP00000029801
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10124,576,962 - 124,721,277 (-)Ensembl
RefSeq Acc Id: XM_003816302   ⟹   XP_003816350
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28135,588,322 - 135,735,921 (-)NCBI
NHGRI_mPanPan110135,593,728 - 135,741,271 (-)NCBI
Mhudiblu_PPA_v010120,302,984 - 120,449,022 (-)NCBI
PanPan1.110124,576,161 - 124,721,359 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034931651   ⟹   XP_034787542
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28135,591,606 - 135,735,893 (-)NCBI
NHGRI_mPanPan110135,596,956 - 135,741,266 (-)NCBI
Mhudiblu_PPA_v010120,305,270 - 120,448,704 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003816350 (Get FASTA)   NCBI Sequence Viewer  
  XP_034787542 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000029797
  ENSPPAP00000029797.1
  ENSPPAP00000029801.1
Reference Protein Sequences
RefSeq Acc Id: XP_003816350   ⟸   XM_003816302
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BN00 (UniProtKB/TrEMBL),   A0A2R9BT97 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034787542   ⟸   XM_034931651
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BT97 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000029801   ⟸   ENSPPAT00000052652
RefSeq Acc Id: ENSPPAP00000029797   ⟸   ENSPPAT00000052648
Protein Domains
F5/8 type C


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037917 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000052648.1 UniProtKB/TrEMBL
  ENSPPAT00000052652.1 UniProtKB/TrEMBL
Gene3D-CATH Carboxypeptidase-like, regulatory domain UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro CarboxyPept-like_regulatory UniProtKB/TrEMBL
  FA58C UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
KEGG Report pps:100989466 UniProtKB/TrEMBL
NCBI Gene CPXM2 ENTREZGENE
PANTHER INACTIVE CARBOXYPEPTIDASE-LIKE PROTEIN X2 UniProtKB/TrEMBL
  PROTEASE M14 CARBOXYPEPTIDASE UniProtKB/TrEMBL
Pfam CarboxypepD_reg UniProtKB/TrEMBL
  F5_F8_type_C UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
PRINTS CRBOXYPTASEA UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_ZN_1 UniProtKB/TrEMBL
  FA58C_1 UniProtKB/TrEMBL
  FA58C_2 UniProtKB/TrEMBL
  FA58C_3 UniProtKB/TrEMBL
SMART FA58C UniProtKB/TrEMBL
  Zn_pept UniProtKB/TrEMBL
Superfamily-SCOP SSF49464 UniProtKB/TrEMBL
  SSF49785 UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A2R9BN00 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BT97 ENTREZGENE, UniProtKB/TrEMBL