ITIH3 (inter-alpha-trypsin inhibitor heavy chain 3) - Rat Genome Database

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Gene: ITIH3 (inter-alpha-trypsin inhibitor heavy chain 3) Pan paniscus
Analyze
Symbol: ITIH3
Name: inter-alpha-trypsin inhibitor heavy chain 3
RGD ID: 11867565
Description: ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN hyaluronan metabolic process (inferred); ASSOCIATED WITH congenital disorder of glycosylation In (ortholog); hepatocellular carcinoma (ortholog); FOUND IN extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inter-alpha-trypsin inhibitor heavy chain H3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2252,786,787 - 52,803,297 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1352,791,574 - 52,807,958 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0352,733,966 - 52,750,198 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1353,961,476 - 53,976,065 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,961,451 - 53,976,065 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ITIH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2252,786,787 - 52,803,297 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1352,791,574 - 52,807,958 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0352,733,966 - 52,750,198 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1353,961,476 - 53,976,065 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,961,451 - 53,976,065 (+)Ensemblpanpan1.1panPan2
ITIH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,794,796 - 52,808,797 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl352,794,768 - 52,808,799 (+)EnsemblGRCh38hg38GRCh38
GRCh37352,828,812 - 52,842,813 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,803,824 - 52,818,065 (+)NCBINCBI36Build 36hg18NCBI36
Build 34352,803,853 - 52,817,854NCBI
Celera352,807,505 - 52,821,742 (+)NCBICelera
Cytogenetic Map3p21.1NCBI
HuRef352,890,445 - 52,904,683 (+)NCBIHuRef
CHM1_1352,780,986 - 52,795,224 (+)NCBICHM1_1
T2T-CHM13v2.0352,827,705 - 52,841,707 (+)NCBIT2T-CHM13v2.0
Itih3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,630,529 - 30,645,748 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1430,630,529 - 30,645,717 (-)EnsemblGRCm39 Ensembl
GRCm381430,908,572 - 30,923,787 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1430,908,572 - 30,923,760 (-)EnsemblGRCm38mm10GRCm38
MGSCv371431,721,758 - 31,736,773 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361429,737,582 - 29,752,553 (-)NCBIMGSCv36mm8
Celera1427,165,744 - 27,180,756 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.09NCBI
Itih3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8166,108,378 - 6,123,609 (-)NCBIGRCr8
mRatBN7.2166,101,922 - 6,117,154 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl166,101,930 - 6,116,924 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx166,113,241 - 6,128,042 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,258,702 - 7,273,506 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0166,120,667 - 6,135,331 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0166,983,779 - 7,007,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl166,992,062 - 7,007,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0166,910,530 - 6,933,416 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,341,043 - 6,358,767 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1166,341,044 - 6,358,765 (-)NCBI
Celera169,072,721 - 9,087,644 (+)NCBICelera
Cytogenetic Map16p16NCBI
Itih3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,753,996 - 2,767,324 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,753,974 - 2,767,436 (+)NCBIChiLan1.0ChiLan1.0
ITIH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,032,485 - 37,035,941 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,003,374 - 37,017,395 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02037,372,140 - 37,386,102 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,372,141 - 37,386,063 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.02037,144,184 - 37,158,164 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02037,421,715 - 37,435,675 (-)NCBIUU_Cfam_GSD_1.0
Itih3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,414,614 - 170,430,165 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364733,553,210 - 3,568,636 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364733,553,210 - 3,568,636 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITIH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,906,538 - 34,933,706 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,911,104 - 34,924,881 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21338,106,334 - 38,120,182 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITIH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12214,176,656 - 14,191,256 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2214,177,334 - 14,191,353 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041152,706,611 - 152,721,211 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itih3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248224,416,074 - 4,429,623 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248224,415,962 - 4,429,660 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000034434   ⟹   ENSPPAP00000011773
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl353,961,451 - 53,976,065 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000034447   ⟹   ENSPPAP00000011786
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl353,962,119 - 53,975,947 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000034453   ⟹   ENSPPAP00000011792
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl353,962,119 - 53,975,947 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000034457   ⟹   ENSPPAP00000011796
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl353,962,119 - 53,975,947 (+)Ensembl
RefSeq Acc Id: XM_008972098   ⟹   XP_008970346
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2252,786,787 - 52,803,297 (+)NCBI
NHGRI_mPanPan1352,791,574 - 52,807,958 (+)NCBI
Mhudiblu_PPA_v0352,733,966 - 52,750,198 (+)NCBI
PanPan1.1353,961,476 - 53,976,065 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055110050   ⟹   XP_054966025
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2252,786,787 - 52,803,297 (+)NCBI
NHGRI_mPanPan1352,791,574 - 52,807,958 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008970346 (Get FASTA)   NCBI Sequence Viewer  
  XP_054966025 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000011773.1
  ENSPPAP00000011786.1
  ENSPPAP00000011792.1
  ENSPPAP00000011796.1
Reference Protein Sequences
RefSeq Acc Id: XP_008970346   ⟸   XM_008972098
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A8Q1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000011773   ⟸   ENSPPAT00000034434
RefSeq Acc Id: ENSPPAP00000011796   ⟸   ENSPPAT00000034457
RefSeq Acc Id: ENSPPAP00000011792   ⟸   ENSPPAT00000034453
RefSeq Acc Id: ENSPPAP00000011786   ⟸   ENSPPAT00000034447
RefSeq Acc Id: XP_054966025   ⟸   XM_055110050
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A8Q1 (UniProtKB/TrEMBL)
Protein Domains
VIT   VWFA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029064 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000034434.1 UniProtKB/TrEMBL
  ENSPPAT00000034447.1 UniProtKB/TrEMBL
  ENSPPAT00000034453.1 UniProtKB/TrEMBL
  ENSPPAT00000034457.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
InterPro ITI_HC_C UniProtKB/TrEMBL
  VIT UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100977578 UniProtKB/TrEMBL
NCBI Gene ITIH3 ENTREZGENE
PANTHER INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN FAMILY MEMBER UniProtKB/TrEMBL
  INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H3 UniProtKB/TrEMBL
Pfam ITI_HC_C UniProtKB/TrEMBL
  VIT UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
PROSITE VIT UniProtKB/TrEMBL
  VWFA UniProtKB/TrEMBL
SMART VIT UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
Superfamily-SCOP SSF53300 UniProtKB/TrEMBL
UniProt A0A2R9A3A7_PANPA UniProtKB/TrEMBL
  A0A2R9A3B5_PANPA UniProtKB/TrEMBL
  A0A2R9A8Q1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A8R1_PANPA UniProtKB/TrEMBL