EIF2B4 (eukaryotic translation initiation factor 2B subunit delta) - Rat Genome Database

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Gene: EIF2B4 (eukaryotic translation initiation factor 2B subunit delta) Pan paniscus
Analyze
Symbol: EIF2B4
Name: eukaryotic translation initiation factor 2B subunit delta
RGD ID: 11859614
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); translation initiation factor activity (ortholog); translation initiation factor binding (ortholog); INVOLVED IN hippocampus development (ortholog); negative regulation of guanyl-nucleotide exchange factor activity (ortholog); response to glucose (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH genetic disease (ortholog); Leukoencephalopathies (ortholog); leukoencephalopathy with vanishing white matter (ortholog); FOUND IN eukaryotic translation initiation factor 2B complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: translation initiation factor eIF-2B subunit delta; translation initiation factor eIF2B subunit delta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21299,140,159 - 99,146,332 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A99,144,139 - 99,150,300 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A27,368,189 - 27,374,265 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A27,456,571 - 27,462,706 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A27,456,457 - 27,462,706 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
EIF2B4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21299,140,159 - 99,146,332 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A99,144,139 - 99,150,300 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A27,368,189 - 27,374,265 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A27,456,571 - 27,462,706 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A27,456,457 - 27,462,706 (-)Ensemblpanpan1.1panPan2
EIF2B4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38227,364,352 - 27,370,338 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl227,364,352 - 27,370,338 (-)EnsemblGRCh38hg38GRCh38
GRCh37227,587,219 - 27,593,205 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36227,440,723 - 27,446,828 (-)NCBINCBI36Build 36hg18NCBI36
Build 34227,498,880 - 27,504,570NCBI
Celera227,433,890 - 27,439,990 (-)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef227,329,223 - 27,335,327 (-)NCBIHuRef
CHM1_1227,517,164 - 27,523,272 (-)NCBICHM1_1
T2T-CHM13v2.0227,406,760 - 27,412,735 (-)NCBIT2T-CHM13v2.0
Eif2b4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39531,344,902 - 31,350,483 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl531,344,902 - 31,350,774 (-)EnsemblGRCm39 Ensembl
GRCm38531,187,558 - 31,193,139 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl531,187,558 - 31,193,430 (-)EnsemblGRCm38mm10GRCm38
MGSCv37531,489,931 - 31,495,512 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36531,464,149 - 31,469,674 (-)NCBIMGSCv36mm8
Celera528,666,608 - 28,672,190 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map517.24NCBI
Eif2b4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8630,903,148 - 30,908,803 (+)NCBIGRCr8
mRatBN7.2625,183,177 - 25,188,832 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,183,186 - 25,188,829 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx625,484,104 - 25,489,668 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0625,799,997 - 25,805,561 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0625,279,071 - 25,284,628 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0626,546,917 - 26,552,474 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl626,546,924 - 26,552,430 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0636,364,317 - 36,369,311 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,159,823 - 25,165,561 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1625,162,775 - 25,168,512 (+)NCBI
Celera624,674,570 - 24,680,134 (+)NCBICelera
Cytogenetic Map6q14NCBI
Eif2b4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554699,328,943 - 9,334,315 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554699,328,900 - 9,334,463 (-)NCBIChiLan1.0ChiLan1.0
EIF2B4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11721,321,329 - 21,326,357 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1721,321,349 - 21,326,244 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1721,213,087 - 21,218,104 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01721,642,644 - 21,647,661 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1721,642,644 - 21,647,572 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11721,329,308 - 21,334,325 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01721,338,998 - 21,344,015 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01721,387,006 - 21,392,025 (-)NCBIUU_Cfam_GSD_1.0
Eif2b4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629265,621,895 - 65,631,786 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364935,213,055 - 5,217,664 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364935,213,036 - 5,217,670 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF2B4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3111,781,648 - 111,786,372 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13111,781,661 - 111,786,377 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23118,691,182 - 118,692,456 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EIF2B4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11480,240,874 - 80,247,555 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1480,240,449 - 80,249,521 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604531,905,087 - 31,911,385 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif2b4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247389,437,554 - 9,443,747 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247389,438,484 - 9,443,931 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000030055   ⟹   ENSPPAP00000007576
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A27,456,457 - 27,462,130 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000030068   ⟹   ENSPPAP00000007582
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A27,456,571 - 27,462,706 (-)Ensembl
RefSeq Acc Id: XM_003827099   ⟹   XP_003827147
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21299,140,159 - 99,146,332 (+)NCBI
NHGRI_mPanPan12A99,144,139 - 99,150,300 (+)NCBI
Mhudiblu_PPA_v02A27,368,189 - 27,374,265 (-)NCBI
PanPan1.12A27,456,571 - 27,462,677 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952475   ⟹   XP_008950723
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21299,140,679 - 99,146,332 (+)NCBI
NHGRI_mPanPan12A99,144,647 - 99,150,300 (+)NCBI
Mhudiblu_PPA_v02A27,368,189 - 27,373,841 (-)NCBI
PanPan1.12A27,456,571 - 27,462,253 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952476   ⟹   XP_008950724
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21299,140,159 - 99,146,332 (+)NCBI
NHGRI_mPanPan12A99,144,139 - 99,150,300 (+)NCBI
Mhudiblu_PPA_v02A27,368,189 - 27,374,231 (-)NCBI
PanPan1.12A27,456,571 - 27,462,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952477   ⟹   XP_008950725
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21299,140,503 - 99,146,332 (+)NCBI
NHGRI_mPanPan12A99,144,430 - 99,150,300 (+)NCBI
Mhudiblu_PPA_v02A27,368,189 - 27,374,142 (-)NCBI
PanPan1.12A27,456,571 - 27,462,549 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952480   ⟹   XP_008950728
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21299,140,159 - 99,146,332 (+)NCBI
NHGRI_mPanPan12A99,144,139 - 99,150,300 (+)NCBI
Mhudiblu_PPA_v02A27,368,189 - 27,374,239 (-)NCBI
PanPan1.12A27,456,575 - 27,462,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024927707   ⟹   XP_024783475
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21299,140,679 - 99,146,332 (+)NCBI
NHGRI_mPanPan12A99,144,647 - 99,150,300 (+)NCBI
Mhudiblu_PPA_v02A27,368,189 - 27,373,841 (-)NCBI
PanPan1.12A27,456,571 - 27,462,253 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034952838   ⟹   XP_034808729
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21299,142,044 - 99,146,332 (+)NCBI
NHGRI_mPanPan12A99,146,010 - 99,150,300 (+)NCBI
Mhudiblu_PPA_v02A27,368,189 - 27,374,265 (-)NCBI
RefSeq Acc Id: XM_063595022   ⟹   XP_063451092
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21299,140,179 - 99,146,332 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008950724   ⟸   XM_008952476
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZRJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003827147   ⟸   XM_003827099
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008950725   ⟸   XM_008952477
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008950723   ⟸   XM_008952475
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008950728   ⟸   XM_008952480
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_024783475   ⟸   XM_024927707
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034808729   ⟸   XM_034952838
- Peptide Label: isoform X8
RefSeq Acc Id: ENSPPAP00000007582   ⟸   ENSPPAT00000030068
RefSeq Acc Id: ENSPPAP00000007576   ⟸   ENSPPAT00000030055
RefSeq Acc Id: XP_063451092   ⟸   XM_063595022
- Peptide Label: isoform X7


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000026873 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000030055.1 UniProtKB/TrEMBL
  ENSPPAT00000030068.1 UniProtKB/TrEMBL
InterPro IF-2B-related UniProtKB/TrEMBL
  IF_2B-like_C UniProtKB/TrEMBL
  NagB/RpiA_transferase-like UniProtKB/TrEMBL
NCBI Gene EIF2B4 ENTREZGENE
PANTHER TRANSLATION INITIATION FACTOR EIF-2B UniProtKB/TrEMBL
  TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA UniProtKB/TrEMBL
Pfam IF-2B UniProtKB/TrEMBL
Superfamily-SCOP SSF100950 UniProtKB/TrEMBL
UniProt A0A2R8ZRI9_PANPA UniProtKB/TrEMBL
  A0A2R8ZRJ0 ENTREZGENE, UniProtKB/TrEMBL