SMAD6 (SMAD family member 6) - Rat Genome Database

Name: SMAD6
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: SMAD6 (SMAD family member 6) Pan paniscus

Analyze

Symbol:

SMAD6

Name:

SMAD family member 6

RGD ID:

11806596

Description:

ENCODES a protein that exhibits chromatin binding (inferred); co-SMAD binding (inferred); I-SMAD binding (inferred); INVOLVED IN aorta development (ortholog); coronary vasculature development (ortholog); heart valve development (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; ASSOCIATED WITH aortic valve disease 1 (ortholog); aortic valve disease 2 (ortholog); bicuspid aortic valve disease (ortholog); FOUND IN cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

mothers against decapentaplegic homolog 6

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SMAD6 (SMAD family member 6)	NCBI	Ortholog
Mus musculus (house mouse):	Smad6 (SMAD family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Smad6 (SMAD family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Smad6 (SMAD family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SMAD6 (SMAD family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Smad6 (SMAD family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SMAD6 (SMAD family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SMAD6 (SMAD family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Smad6 (SMAD family member 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	55,954,503 - 56,034,004 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	60,126,630 - 60,206,563 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	45,648,709 - 45,728,821 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	63,923,356 - 64,001,607 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	63,923,379 - 64,001,154 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

aortic valve disease 1 (ISO)

aortic valve disease 2 (ISO)

bicuspid aortic valve disease (ISO)

Bloom syndrome (ISO)

Bone Fractures (ISO)

colorectal cancer (ISO)

craniosynostosis (ISO)

craniosynostosis 7 (ISO)

Diabetic Nephropathies (ISO)

genetic disease (ISO)

idiopathic pulmonary fibrosis (ISO)

Joubert syndrome 9 (ISO)

Loeys-Dietz syndrome 3 (ISO)

nephritis (ISO)

neuronal ceroid lipofuscinosis (ISO)

Ovarian Neoplasms (ISO)

polydactyly (ISO)

pulmonary hypertension (ISO)

radioulnar synostosis (ISO)

thoracic aortic aneurysm (ISO)

Tracheoesophageal Fistula (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anatomical structure morphogenesis (IEA)

aorta development (IEA,ISO)

aortic valve morphogenesis (IEA)

BMP signaling pathway (IEA)

cell differentiation (IEA)

cell-substrate adhesion (IEA)

coronary vasculature development (IEA,ISO)

fat cell differentiation (IEA)

heart valve development (IEA,ISO)

immune response (IEA)

mitral valve morphogenesis (IEA)

negative regulation of activin receptor signaling pathway (IEA)

negative regulation of apoptotic process (IEA)

negative regulation of BMP signaling pathway (IEA)

negative regulation of cell population proliferation (IEA)

negative regulation of ossification (IEA)

negative regulation of osteoblast differentiation (IEA)

negative regulation of SMAD protein signal transduction (IEA)

negative regulation of transforming growth factor beta receptor signaling pathway (IEA)

outflow tract septum morphogenesis (IEA)

positive regulation of miRNA transcription (IEA)

pulmonary valve morphogenesis (IEA)

regulation of DNA-templated transcription (IEA)

regulation of gene expression (IEA)

regulation of transcription by RNA polymerase II (IEA)

response to estrogen (ISO)

response to laminar fluid shear stress (IEA)

response to lipopolysaccharide (IEA)

SMAD protein signal transduction (IEA)

transforming growth factor beta receptor signaling pathway (IEA)

ureteric bud development (IEA)

ventricular septum development (IEA,ISO)

zygotic specification of dorsal/ventral axis (IEA)

Cellular Component

cytoplasm (IEA,ISO)

cytosol (IEA)

Golgi apparatus (IEA)

heteromeric SMAD protein complex (IEA)

nuclear body (IEA)

nucleoplasm (IEA)

nucleus (IEA)

protein-containing complex (IEA)

transcription regulator complex (IEA)

Molecular Function

chromatin binding (IEA)

co-SMAD binding (IEA)

I-SMAD binding (IEA)

identical protein binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

protein sequestering activity (IEA)

R-SMAD binding (IEA)

transcription cis-regulatory region binding (IEA)

transcription regulator inhibitor activity (IEA)

type I activin receptor binding (IEA)

type I transforming growth factor beta receptor binding (IEA)

ubiquitin protein ligase binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Bone morphogenetic proteins signaling pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

SMAD6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	55,954,503 - 56,034,004 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	60,126,630 - 60,206,563 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	45,648,709 - 45,728,821 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	63,923,356 - 64,001,607 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	63,923,379 - 64,001,154 (+)	Ensembl	panpan1.1		panPan2

SMAD6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	66,702,236 - 66,782,849 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	66,702,236 - 66,782,849 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	66,994,574 - 67,075,187 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	64,781,688 - 64,861,380 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	64,781,723 - 64,861,380	NCBI
Celera	15	43,882,942 - 43,962,620 (+)	NCBI		Celera
Cytogenetic Map	15	q22.31	NCBI
HuRef	15	43,830,247 - 43,909,482 (+)	NCBI		HuRef
CHM1_1	15	67,112,770 - 67,192,414 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	64,524,017 - 64,604,653 (+)	NCBI		T2T-CHM13v2.0

Smad6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	63,860,358 - 63,929,374 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	63,860,358 - 63,929,341 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	63,953,076 - 64,022,085 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	63,953,076 - 64,022,059 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	63,800,883 - 63,869,866 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	63,751,143 - 63,819,327 (-)	NCBI		MGSCv36	mm8
Celera	9	61,176,785 - 61,248,052 (-)	NCBI		Celera
Cytogenetic Map	9	C	NCBI
cM Map	9	34.4	NCBI

Smad6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	73,345,457 - 73,414,985 (-)	NCBI		GRCr8
mRatBN7.2	8	64,450,114 - 64,519,673 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	64,450,114 - 64,519,763 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	69,964,906 - 70,033,580 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	68,237,362 - 68,306,026 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	66,107,492 - 66,176,160 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	68,897,746 - 68,967,221 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	68,898,296 - 68,966,108 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	68,608,372 - 68,677,705 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	68,144,395 - 68,214,652 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	68,163,448 - 68,232,779 (-)	NCBI
Celera	8	63,858,003 - 63,926,291 (-)	NCBI		Celera
Cytogenetic Map	8	q24	NCBI

Smad6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955450	9,005,332 - 9,070,790 (-)	NCBI	ChiLan1.0	ChiLan1.0

SMAD6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	30,938,908 - 31,014,259 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	30,937,849 - 31,014,583 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	30,868,681 - 30,945,004 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	31,135,483 - 31,212,132 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	31,133,955 - 31,211,274 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	31,064,510 - 31,140,721 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	31,124,002 - 31,200,323 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	31,365,990 - 31,442,355 (+)	NCBI		UU_Cfam_GSD_1.0

Smad6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	108,933,410 - 109,008,484 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	26,781,549 - 26,856,571 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	26,781,420 - 26,856,556 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SMAD6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	164,656,887 - 164,735,704 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	164,652,602 - 164,735,084 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	182,396,037 - 182,478,849 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SMAD6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	16,760,117 - 16,841,286 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	16,759,260 - 16,840,240 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	124,628,125 - 124,709,889 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Smad6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624781	6,042,904 - 6,107,860 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624781	6,043,183 - 6,108,959 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003828002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000031632 ⟹ ENSPPAP00000008992

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	63,923,379 - 64,001,154 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000031633 ⟹ ENSPPAP00000008993

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	63,923,379 - 64,001,154 (+)	Ensembl

RefSeq Acc Id:

XM_003828002 ⟹ XP_003828050

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	55,954,503 - 56,034,004 (+)	NCBI
NHGRI_mPanPan1	15	60,126,630 - 60,206,563 (+)	NCBI
Mhudiblu_PPA_v0	15	45,648,709 - 45,728,821 (+)	NCBI
PanPan1.1	15	63,923,356 - 64,001,607 (+)	NCBI

Sequence:

show sequence

CCCCTGGCGCCAAAGGATATCGTATGTTCAGGTCCAAACGCTCGGGGCTGGTGCGGCGACTTTG
GCGAAGTCGTGTGGTCCCCGACCGGGAGGAAGGCGGCAGCGGCGGCGGCGGTGGCGGCGACGAG
GATGGGAGCTTGGGCAGCCGAGCTGAGCCGGCCCCGCGGGCAAGAGAGGGCGGAGGCTGCGGCC
GCTCCGAAGTCCGCCCGGTAGCCCCGCGGCGGCCCCGGGACGCAGTGGGACAGCGAGGCGCCCA
GGGTGCGGGGAGGCGCCGGCGCGCGACGGGGGCCCCCCGACGGCCCATGTCGGAGCCAGGGGCC
GGCGCTGGGAGCTCCCTGCTGGACGTGGCGGAGCCGGGAGGCCCGGGCTGGCTGCCCGAGAGTG
ATTGCGAGACGGTGACCTGCTGTCTCTTTTCGGAGCGGGACGCCGCCGGCGCGCCCCGGGACGC
CAGCGACCCCCTGGCCGGGGCGGCCCTGGAGCCGGCGGGCGGCGGGCGGAGTCGCGAAGCGCGC
TCGCGGCTGCTGCTGCTGGAGCAGGAACTCAAAACGGTCACGTACTCGCTGCTGAAGCGGCTCA
AGGAGCGCTCGCTGGACACGCTGCTGGAGGCGGTGGAGTCCCGCGGCGGCGTGCCGGGCGGCTG
CGTGCTGGTGCCGCGCGCCGACCTCCGCCTGGGCGGCCAGCCCGCGCCGCCGCAGCTGCTGCTC
GGCCGCCTCTTTCGCTGGCCCGACCTGCAGCACGCAGTGGAGCTGAAGCCCCTGTGCGGCTGCC
ACAGCTTCGCCGCCGCCGCCGACGGCCCTACCGTGTGCTGCNAACCCTACCACTTCAGCCGGCT
TTGCGGGCCAGAATCTCCGCCACCTCCCTACTCTCGGCTGTCTCCTCGTGACGAGTACAAGCCA
CTGGATCTGTCCGATTCCACATTGTCTTACACTGAAACGGAGGCTACCAACTCCCTCATCACTG
CTCCGGGTGAATTCTCAGACGCCAGCATGTCTCCGGACGCCACCAAGCCGAGCCACTGGTGCAG
CGTGGCGTACTGGGAGCACCGGACGCGCGTGGGCCGCCTCTATGCGGTGTACGACCAGGCCGTC
AGCATCTTCTACGACCTACCTCAGGGCAGCGGCTTCTGCCTGGGCCAGCTCAACCTGGAGCAGC
GCAGCGAGTCGGTGCGGCGAACGCGCAGCAAGATCGGCTTCGGCATCCTGCTCAGCAAGGAGCC
CGACGGCGTGTGGGCCTACAACCGCGGCGAGCACCCCATCTTCGTCAACTCCCCGACGCTGGAC
GCGCCCGGCGGCCGCGCCCTGGTCGTGCGCAAGGTGCCCCCCGGCTACTCCATCAAGGTGTTCG
ACTTCGAGCGCTCGGGCCTGCAGCACGCGCCCGAGCCCGACGCCGCCGACGGCCCCTACGACCC
CAACAGCGTCCGCATCAGCTTCGCCAAGGGCTGGGGGCCCTGCTACTCCCGGCAGTTCATCACC
TCCTGCCCCTGCTGGCTGGAGATCCTCCTCAACAACCCCAGATAGTGGCGGCCCCGGCGGGAGG
GGCGGGTGGGAGGCCGCGGCCACCGCCACCTGCCGGCCTCGAGAGGGGCCGATGCCCAGAGACA
CAGCCCCCACGGACAAAACCCCCCAGATATCATCTACCTAGATTTAATATAAAGTTTTATATAT
TATATGGAAATATATATTATACTTGTAATTATGGAGTCATTTTTACAATGTAATTATTTATGTA
TGGTGCAATGTGTGTATATGGACAAAACAAGAAAGATGCACTTTGGCTTATAATTCTTTCAATA
CAGATATATTTTCTTTCTCTTCCTCCTTCCTCTTCCTTACTTTTTATATATATATATAAAGAAA
ATGATACAGCAGAGCTAGGTGGAAAAGCCTGGGTTTGGTGTATGGTTTTTGAGATATTAATGCC
CAGACAAAAAGCTAATACCAGTCACTCGATAATAAAGTATTCGCATTATA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003828050	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000008992.1
	ENSPPAP00000008993.1

RefSeq Acc Id:

XP_003828050 ⟸ XM_003828002

- UniProtKB:

A0A2R8ZZ54 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFRSKRSGLVRRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVA
PRRPRDAVGQRGAQGAGRRRRATGAPRRPMSEPGAGAGSSLLDVAEPGGPGWLPESDCETVTCC
LFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTL
LEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAAD
GPTVCCXPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDA
SMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRT
RSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLQ
HAPEPDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNPR

hide sequence

RefSeq Acc Id:

ENSPPAP00000008993 ⟸ ENSPPAT00000031633

RefSeq Acc Id:

ENSPPAP00000008992 ⟸ ENSPPAT00000031632

Protein Domains

MH1 MH2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000027722	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000031632.1	UniProtKB/TrEMBL
	ENSPPAT00000031633.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.200.10	UniProtKB/TrEMBL
	3.90.520.10	UniProtKB/TrEMBL
InterPro	Dwarfin	UniProtKB/TrEMBL
	MAD_homology1_Dwarfin-type	UniProtKB/TrEMBL
	MAD_homology_MH1	UniProtKB/TrEMBL
	SMAD-like_dom_sf	UniProtKB/TrEMBL
	SMAD_dom_Dwarfin-type	UniProtKB/TrEMBL
	SMAD_FHA_dom_sf	UniProtKB/TrEMBL
	SMAD_MH1_sf	UniProtKB/TrEMBL
NCBI Gene	SMAD6	ENTREZGENE
PANTHER	MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 6	UniProtKB/TrEMBL
	PTHR13703	UniProtKB/TrEMBL
Pfam	MH1	UniProtKB/TrEMBL
	MH2	UniProtKB/TrEMBL
PROSITE	MH1	UniProtKB/TrEMBL
	MH2	UniProtKB/TrEMBL
SMART	DWA	UniProtKB/TrEMBL
	DWB	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49879	UniProtKB/TrEMBL
	SSF56366	UniProtKB/TrEMBL
UniProt	A0A2R8ZZ54	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9A176_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)