ANO1 (anoctamin 1) - Rat Genome Database

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Gene: ANO1 (anoctamin 1) Pan paniscus
Analyze
Symbol: ANO1
Name: anoctamin 1
RGD ID: 11783893
Description: ENCODES a protein that exhibits intracellularly calcium-gated chloride channel activity (ortholog); phospholipid scramblase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cellular response to heat (ortholog); cellular response to peptide (ortholog); chloride transmembrane transport (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); intellectual disability (ortholog); Moyamoya Disease 7 (ortholog); FOUND IN external side of plasma membrane (ortholog); glutamatergic synapse (ortholog); presynaptic membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: anoctamin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2970,953,323 - 71,156,782 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11171,996,720 - 72,200,997 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01165,064,415 - 65,287,160 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11168,475,833 - 68,576,451 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1168,473,555 - 68,576,451 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ANO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2970,953,323 - 71,156,782 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11171,996,720 - 72,200,997 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01165,064,415 - 65,287,160 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11168,475,833 - 68,576,451 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1168,473,555 - 68,576,451 (+)Ensemblpanpan1.1panPan2
ANO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381169,965,997 - 70,189,530 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1169,985,907 - 70,189,530 (+)EnsemblGRCh38hg38GRCh38
GRCh371169,832,013 - 70,035,636 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361169,602,294 - 69,713,282 (+)NCBINCBI36Build 36hg18NCBI36
Build 341169,602,293 - 69,713,281NCBI
Celera1167,191,110 - 67,302,276 (+)NCBICelera
Cytogenetic Map11q13.3NCBI
HuRef1166,184,385 - 66,295,481 (+)NCBIHuRef
CHM1_11169,807,423 - 69,918,650 (+)NCBICHM1_1
T2T-CHM13v2.01169,983,135 - 70,204,739 (+)NCBIT2T-CHM13v2.0
Ano1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397144,142,286 - 144,305,762 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7144,142,286 - 144,305,711 (-)EnsemblGRCm39 Ensembl
GRCm387144,588,549 - 144,752,026 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7144,588,549 - 144,751,974 (-)EnsemblGRCm38mm10GRCm38
MGSCv377151,774,550 - 151,924,383 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367144,398,033 - 144,547,933 (-)NCBIMGSCv36mm8
Celera7144,352,484 - 144,502,805 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.85NCBI
Ano1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81209,180,755 - 209,329,413 (-)NCBIGRCr8
mRatBN7.21199,751,439 - 199,900,099 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1199,751,439 - 199,900,069 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1208,134,731 - 208,283,554 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01215,218,908 - 215,367,493 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01207,893,103 - 208,041,684 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01217,754,349 - 217,902,540 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1217,754,336 - 217,902,473 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,612,597 - 224,760,421 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41205,018,529 - 205,166,049 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11205,173,453 - 205,319,650 (-)NCBI
Celera1197,310,791 - 197,458,719 (-)NCBICelera
Cytogenetic Map1q42NCBI
Ano1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542216,064,475 - 16,214,360 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542216,064,526 - 16,213,614 (-)NCBIChiLan1.0ChiLan1.0
ANO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11848,108,310 - 48,249,021 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1848,108,806 - 48,189,471 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1846,718,498 - 46,799,937 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01848,785,861 - 48,867,273 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1848,786,000 - 48,928,399 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11848,232,943 - 48,314,303 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01847,818,706 - 47,900,075 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01848,564,796 - 48,646,239 (-)NCBIUU_Cfam_GSD_1.0
Ano1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049474,204,855 - 4,284,022 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936599648,659 - 719,310 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936599647,230 - 726,371 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl23,202,166 - 3,373,411 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.123,202,269 - 3,373,409 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.221,575,589 - 1,606,417 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANO1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114,373,256 - 4,581,914 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl14,373,252 - 4,490,557 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038101,658,017 - 101,859,087 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ano1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476717,072,515 - 17,174,970 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476717,070,989 - 17,246,822 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000019844   ⟹   ENSPPAP00000004291
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1168,473,555 - 68,575,059 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000019869   ⟹   ENSPPAP00000004302
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1168,475,828 - 68,574,923 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000019884   ⟹   ENSPPAP00000004303
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1168,475,833 - 68,576,451 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000019897   ⟹   ENSPPAP00000004308
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1168,499,545 - 68,574,923 (+)Ensembl
RefSeq Acc Id: XM_055093698   ⟹   XP_054949673
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2970,953,323 - 71,156,781 (+)NCBI
NHGRI_mPanPan11171,996,720 - 72,200,996 (+)NCBI
RefSeq Acc Id: XM_055093699   ⟹   XP_054949674
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2970,953,323 - 71,156,773 (+)NCBI
NHGRI_mPanPan11171,996,720 - 72,200,988 (+)NCBI
RefSeq Acc Id: XM_055093700   ⟹   XP_054949675
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2970,953,324 - 71,156,782 (+)NCBI
NHGRI_mPanPan11171,996,722 - 72,200,997 (+)NCBI
RefSeq Acc Id: XM_055093701   ⟹   XP_054949676
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2971,052,796 - 71,156,773 (+)NCBI
NHGRI_mPanPan11172,096,155 - 72,200,988 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000004291   ⟸   ENSPPAT00000019844
RefSeq Acc Id: ENSPPAP00000004303   ⟸   ENSPPAT00000019884
RefSeq Acc Id: ENSPPAP00000004302   ⟸   ENSPPAT00000019869
RefSeq Acc Id: ENSPPAP00000004308   ⟸   ENSPPAT00000019897
RefSeq Acc Id: XP_054949673   ⟸   XM_055093698
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054949674   ⟸   XM_055093699
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054949675   ⟸   XM_055093700
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054949676   ⟸   XM_055093701
- Peptide Label: isoform X4
Protein Domains
Anoctamin dimerisation   Anoctamin transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000018068 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000019844.1 UniProtKB/TrEMBL
  ENSPPAT00000019869.1 UniProtKB/TrEMBL
  ENSPPAT00000019884.1 UniProtKB/TrEMBL
  ENSPPAT00000019897.1 UniProtKB/TrEMBL
InterPro Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
  Anoctamin_TM UniProtKB/TrEMBL
NCBI Gene ANO1 ENTREZGENE
PANTHER PTHR12308 UniProtKB/TrEMBL
  PTHR12308:SF13 UniProtKB/TrEMBL
Pfam Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
UniProt A0A2R8ZHR6_PANPA UniProtKB/TrEMBL
  A0A2R8ZKA7_PANPA UniProtKB/TrEMBL
  A0A2R8ZND9_PANPA UniProtKB/TrEMBL
  A0A2R8ZNE5_PANPA UniProtKB/TrEMBL