DOCK7 (dedicator of cytokinesis 7) - Rat Genome Database

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Gene: DOCK7 (dedicator of cytokinesis 7) Pan paniscus
Analyze
Symbol: DOCK7
Name: dedicator of cytokinesis 7
RGD ID: 11688941
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); small GTPase binding (inferred); INVOLVED IN hematopoietic progenitor cell differentiation (ortholog); interkinetic nuclear migration (ortholog); negative regulation of cold-induced thermogenesis (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 23 (ortholog); epilepsy (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN COP9 signalosome (ortholog); neuromuscular junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dedicator of cytokinesis protein 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,713,217 - 61,946,371 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1163,528,826 - 63,760,513 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,529,227 - 63,740,970 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
DOCK7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,713,217 - 61,946,371 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1163,528,826 - 63,760,513 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,529,227 - 63,740,970 (-)Ensemblpanpan1.1panPan2
DOCK7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,454,726 - 62,688,386 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,454,298 - 62,688,386 (-)EnsemblGRCh38hg38GRCh38
GRCh37162,920,397 - 63,154,057 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,692,985 - 62,926,557 (-)NCBINCBI36Build 36hg18NCBI36
Build 34162,632,417 - 62,865,990NCBI
Celera161,209,606 - 61,442,836 (-)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef161,032,437 - 61,265,993 (-)NCBIHuRef
CHM1_1163,035,730 - 63,269,026 (-)NCBICHM1_1
T2T-CHM13v2.0162,333,313 - 62,566,591 (-)NCBIT2T-CHM13v2.0
Dock7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39498,824,669 - 99,019,190 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl498,824,908 - 99,009,152 (-)EnsemblGRCm39 Ensembl
GRCm38498,936,659 - 99,130,953 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl498,936,671 - 99,120,915 (-)EnsemblGRCm38mm10GRCm38
MGSCv37498,603,356 - 98,787,606 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36498,428,693 - 98,612,878 (-)NCBIMGSCv36mm8
Celera497,303,728 - 97,492,465 (-)NCBICelera
Cytogenetic Map4C6NCBI
cM Map445.6NCBI
Dock7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85118,714,863 - 118,898,362 (-)NCBIGRCr8
mRatBN7.25113,599,371 - 113,782,871 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5113,600,198 - 113,782,813 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5116,173,874 - 116,331,721 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05117,899,210 - 118,057,047 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05117,961,741 - 118,119,584 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05117,595,194 - 117,780,844 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5117,596,136 - 117,780,777 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05121,536,701 - 121,718,634 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45119,377,149 - 119,535,973 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5112,163,983 - 112,318,639 (-)NCBICelera
Cytogenetic Map5q33NCBI
Dock7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542327,044,341 - 27,233,710 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542327,043,621 - 27,233,710 (+)NCBIChiLan1.0ChiLan1.0
DOCK7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1547,435,209 - 47,653,312 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl547,462,224 - 47,653,163 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha547,495,341 - 47,714,450 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0547,618,819 - 47,837,750 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl547,618,797 - 47,837,603 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1547,574,121 - 47,792,708 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0547,519,806 - 47,739,083 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0547,782,016 - 48,001,146 (+)NCBIUU_Cfam_GSD_1.0
Dock7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505875,846,153 - 76,038,630 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936692162,390 - 353,721 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936692161,979 - 354,028 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DOCK7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6149,748,036 - 149,972,168 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16149,745,375 - 149,971,853 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26138,013,920 - 138,172,803 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DOCK7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12070,371,775 - 70,599,311 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2070,372,534 - 70,598,614 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603346,854,700 - 47,083,061 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dock7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474231,189,852 - 31,390,478 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474231,189,890 - 31,390,284 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000018594   ⟹   ENSPPAP00000004000
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl163,529,227 - 63,740,970 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000018603   ⟹   ENSPPAP00000004005
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl163,529,227 - 63,736,064 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000018641   ⟹   ENSPPAP00000004014
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl163,657,853 - 63,736,061 (-)Ensembl
RefSeq Acc Id: XM_034966435   ⟹   XP_034822326
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBI
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBI
Mhudiblu_PPA_v0161,713,505 - 61,946,370 (-)NCBI
RefSeq Acc Id: XM_034966442   ⟹   XP_034822333
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBI
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBI
Mhudiblu_PPA_v0161,713,505 - 61,946,352 (-)NCBI
RefSeq Acc Id: XM_034966450   ⟹   XP_034822341
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBI
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBI
Mhudiblu_PPA_v0161,713,217 - 61,946,352 (-)NCBI
RefSeq Acc Id: XM_034966452   ⟹   XP_034822343
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBI
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBI
Mhudiblu_PPA_v0161,713,217 - 61,946,352 (-)NCBI
RefSeq Acc Id: XM_034966456   ⟹   XP_034822347
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBI
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBI
Mhudiblu_PPA_v0161,713,505 - 61,946,343 (-)NCBI
RefSeq Acc Id: XM_034966459   ⟹   XP_034822350
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBI
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBI
Mhudiblu_PPA_v0161,713,217 - 61,946,352 (-)NCBI
RefSeq Acc Id: XM_034966461   ⟹   XP_034822352
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBI
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBI
Mhudiblu_PPA_v0161,713,217 - 61,946,352 (-)NCBI
RefSeq Acc Id: XM_034966462   ⟹   XP_034822353
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,267,938 (+)NCBI
NHGRI_mPanPan11163,313,398 - 163,417,278 (+)NCBI
Mhudiblu_PPA_v0161,842,478 - 61,946,371 (-)NCBI
RefSeq Acc Id: XM_034966463   ⟹   XP_034822354
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBI
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBI
Mhudiblu_PPA_v0161,713,505 - 61,946,343 (-)NCBI
RefSeq Acc Id: XM_055091843   ⟹   XP_054947818
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBI
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBI
RefSeq Acc Id: XM_055091862   ⟹   XP_054947837
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBI
NHGRI_mPanPan11163,313,398 - 163,546,558 (+)NCBI
RefSeq Acc Id: XM_063600783   ⟹   XP_063456853
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,163,998 - 164,396,907 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034822352   ⟸   XM_034966461
- Peptide Label: isoform X10
- UniProtKB: A0A2R8ZG82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034822350   ⟸   XM_034966459
- Peptide Label: isoform X9
- UniProtKB: A0A2R8ZG82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034822343   ⟸   XM_034966452
- Peptide Label: isoform X7
- UniProtKB: A0A2R8ZG82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034822341   ⟸   XM_034966450
- Peptide Label: isoform X5
- UniProtKB: A0A2R8ZG82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034822326   ⟸   XM_034966435
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZG82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034822333   ⟸   XM_034966442
- Peptide Label: isoform X4
- UniProtKB: A0A2R8ZG82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034822347   ⟸   XM_034966456
- Peptide Label: isoform X8
- UniProtKB: A0A2R8ZG82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034822354   ⟸   XM_034966463
- Peptide Label: isoform X12
- UniProtKB: A0A2R8ZG82 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034822353   ⟸   XM_034966462
- Peptide Label: isoform X11
- UniProtKB: A0A2R8ZG88 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000004000   ⟸   ENSPPAT00000018594
RefSeq Acc Id: ENSPPAP00000004005   ⟸   ENSPPAT00000018603
RefSeq Acc Id: ENSPPAP00000004014   ⟸   ENSPPAT00000018641
RefSeq Acc Id: XP_054947818   ⟸   XM_055091843
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054947837   ⟸   XM_055091862
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063456853   ⟸   XM_063600783
- Peptide Label: isoform X2
Protein Domains
C2 DOCK-type   DOCKER


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000016435 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000018594.1 UniProtKB/TrEMBL
  ENSPPAT00000018603.1 UniProtKB/TrEMBL
  ENSPPAT00000018641.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.740 UniProtKB/TrEMBL
  1.25.40.410 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_Dock-C UniProtKB/TrEMBL
  C2_DOCK-type_domain UniProtKB/TrEMBL
  C2_DOCKER_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  DOCK UniProtKB/TrEMBL
  DOCK_C/D_N UniProtKB/TrEMBL
  DOCK_C_lobe_A UniProtKB/TrEMBL
  DOCK_C_lobe_C UniProtKB/TrEMBL
  DOCKER_Lobe_A UniProtKB/TrEMBL
  DOCKER_Lobe_B UniProtKB/TrEMBL
  DOCKER_Lobe_C UniProtKB/TrEMBL
NCBI Gene DOCK7 ENTREZGENE
PANTHER DEDICATOR OF CYTOKINESIS PROTEIN 7 UniProtKB/TrEMBL
  PTHR23317 UniProtKB/TrEMBL
Pfam DHR-2 UniProtKB/TrEMBL
  DHR-2_Lobe_B UniProtKB/TrEMBL
  DHR-2_Lobe_C UniProtKB/TrEMBL
  DOCK-C2 UniProtKB/TrEMBL
  DUF3398 UniProtKB/TrEMBL
PROSITE C2_DOCK UniProtKB/TrEMBL
  DOCKER UniProtKB/TrEMBL
UniProt A0A2R8ZG76_PANPA UniProtKB/TrEMBL
  A0A2R8ZG82 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZG88 ENTREZGENE, UniProtKB/TrEMBL