CMTM3 (CKLF like MARVEL transmembrane domain containing 3) - Rat Genome Database

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Gene: CMTM3 (CKLF like MARVEL transmembrane domain containing 3) Pan paniscus
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Symbol: CMTM3
Name: CKLF like MARVEL transmembrane domain containing 3
RGD ID: 11672588
Description: INVOLVED IN blastocyst hatching (ortholog); positive regulation of B cell receptor signaling pathway (ortholog); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); cataract 5 multiple types (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CKLF-like MARVEL transmembrane domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21876,104,957 - 76,114,452 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11682,016,178 - 82,026,869 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01646,920,341 - 46,930,047 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11666,022,704 - 66,031,525 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1666,022,698 - 66,031,525 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
cytoplasmic vesicle  (IEA,ISO)
cytosol  (IEA,ISO)
membrane  (IEA)
nuclear membrane  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CMTM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21876,104,957 - 76,114,452 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11682,016,178 - 82,026,869 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01646,920,341 - 46,930,047 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11666,022,704 - 66,031,525 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1666,022,698 - 66,031,525 (+)Ensemblpanpan1.1panPan2
CMTM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381666,603,996 - 66,613,892 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1666,603,874 - 66,613,892 (+)EnsemblGRCh38hg38GRCh38
GRCh371666,637,899 - 66,647,795 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,195,703 - 65,205,296 (+)NCBINCBI36Build 36hg18NCBI36
Build 341665,195,713 - 65,205,294NCBI
Celera1651,144,695 - 51,154,288 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1652,513,869 - 52,523,565 (+)NCBIHuRef
CHM1_11668,045,115 - 68,054,938 (+)NCBICHM1_1
T2T-CHM13v2.01672,397,883 - 72,408,187 (+)NCBIT2T-CHM13v2.0
Cmtm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398105,065,993 - 105,074,304 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8105,066,042 - 105,074,304 (+)EnsemblGRCm39 Ensembl
GRCm388104,339,383 - 104,347,672 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8104,339,410 - 104,347,672 (+)EnsemblGRCm38mm10GRCm38
MGSCv378106,864,494 - 106,871,572 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368107,229,723 - 107,236,801 (+)NCBIMGSCv36mm8
Celera8108,574,852 - 108,578,767 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Cmtm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr819629,000 - 637,152 (-)NCBIGRCr8
mRatBN7.219622,563 - 630,721 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl19604,458 - 629,790 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx19618,378 - 625,233 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,385,179 - 1,392,034 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.019660,393 - 667,248 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.019830,874 - 838,528 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl19830,877 - 838,099 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.019829,210 - 836,752 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.419579,430 - 586,297 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.119579,428 - 586,653 (-)NCBI
Celera19618,503 - 625,370 (-)NCBICelera
Cytogenetic Map19p14NCBI
Cmtm3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543323,178,061 - 23,185,666 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543323,178,062 - 23,185,666 (+)NCBIChiLan1.0ChiLan1.0
CMTM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1582,660,995 - 82,667,360 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl582,661,256 - 82,667,372 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha582,649,435 - 82,655,885 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0583,097,745 - 83,104,133 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1582,920,762 - 82,927,149 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0582,607,803 - 82,614,213 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0583,246,277 - 83,252,668 (-)NCBIUU_Cfam_GSD_1.0
Cmtm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934942,652,485 - 42,662,194 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647516,929,628 - 16,931,385 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647516,929,726 - 16,935,403 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CMTM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl627,308,141 - 27,317,308 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1627,308,146 - 27,320,449 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CMTM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1552,302,606 - 52,312,277 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl552,303,288 - 52,311,165 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604723,602,277 - 23,611,446 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cmtm3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474619,830,839 - 19,839,430 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474619,830,839 - 19,840,350 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000053979   ⟹   ENSPPAP00000031115
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1666,022,698 - 66,031,525 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000053980   ⟹   ENSPPAP00000031116
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1666,022,698 - 66,030,281 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000053981   ⟹   ENSPPAP00000031117
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1666,022,698 - 66,027,500 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000053982   ⟹   ENSPPAP00000031118
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1666,022,707 - 66,030,761 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000053984   ⟹   ENSPPAP00000031120
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1666,026,063 - 66,028,521 (+)Ensembl
RefSeq Acc Id: XM_034940366   ⟹   XP_034796257
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21876,104,957 - 76,114,452 (+)NCBI
NHGRI_mPanPan11682,016,178 - 82,026,869 (+)NCBI
Mhudiblu_PPA_v01646,920,341 - 46,930,047 (+)NCBI
RefSeq Acc Id: XM_034940367   ⟹   XP_034796258
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21876,104,957 - 76,114,452 (+)NCBI
NHGRI_mPanPan11682,016,178 - 82,026,869 (+)NCBI
Mhudiblu_PPA_v01646,920,341 - 46,930,047 (+)NCBI
RefSeq Acc Id: XM_063597627   ⟹   XP_063453697
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21876,104,957 - 76,114,452 (+)NCBI
RefSeq Acc Id: XM_063597628   ⟹   XP_063453698
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21876,106,627 - 76,114,452 (+)NCBI
RefSeq Acc Id: XM_063597629   ⟹   XP_063453699
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21876,105,914 - 76,114,452 (+)NCBI
RefSeq Acc Id: XP_034796257   ⟸   XM_034940366
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BN62 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034796258   ⟸   XM_034940367
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BN62 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000031118   ⟸   ENSPPAT00000053982
RefSeq Acc Id: ENSPPAP00000031120   ⟸   ENSPPAT00000053984
RefSeq Acc Id: ENSPPAP00000031116   ⟸   ENSPPAT00000053980
RefSeq Acc Id: ENSPPAP00000031117   ⟸   ENSPPAT00000053981
RefSeq Acc Id: ENSPPAP00000031115   ⟸   ENSPPAT00000053979
RefSeq Acc Id: XP_063453697   ⟸   XM_063597627
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063453699   ⟸   XM_063597629
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063453698   ⟸   XM_063597628
- Peptide Label: isoform X2
Protein Domains
MARVEL


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038495 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000053979.1 UniProtKB/TrEMBL
  ENSPPAT00000053980.1 UniProtKB/TrEMBL
  ENSPPAT00000053981.1 UniProtKB/TrEMBL
  ENSPPAT00000053982.1 UniProtKB/TrEMBL
  ENSPPAT00000053984.1 UniProtKB/TrEMBL
InterPro Marvel UniProtKB/TrEMBL
NCBI Gene CMTM3 ENTREZGENE
PANTHER CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
  MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN UniProtKB/TrEMBL
Pfam MARVEL UniProtKB/TrEMBL
PROSITE MARVEL UniProtKB/TrEMBL
UniProt A0A2R9BN62 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BN67_PANPA UniProtKB/TrEMBL
  A0A2R9BN86_PANPA UniProtKB/TrEMBL
  A0A2R9BRR4_PANPA UniProtKB/TrEMBL
  A0A2R9BX86_PANPA UniProtKB/TrEMBL