Spem3 (SPEM family member 3) - Rat Genome Database

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Gene: Spem3 (SPEM family member 3) Mus musculus
Analyze
Symbol: Spem3
Name: SPEM family member 3
RGD ID: 10010246
MGI Page MGI
Description: Predicted to be involved in flagellated sperm motility and sperm individualization. Predicted to be active in cytoplasm. Orthologous to human SPEM3 (SPEM family member 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: flocculation protein FLO11; Gm39566; uncharacterized protein LOC105243794; uncharacterized protein SPEM3
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,701,718 - 69,706,170 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,701,791 - 69,706,124 (-)EnsemblGRCm39 Ensembl
GRCm381169,810,892 - 69,815,344 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,810,965 - 69,815,298 (-)EnsemblGRCm38mm10GRCm38
Cytogenetic Map11B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

References
Additional References at PubMed
PMID:21873635  


Genomics

Comparative Map Data
Spem3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,701,718 - 69,706,170 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,701,791 - 69,706,124 (-)EnsemblGRCm39 Ensembl
GRCm381169,810,892 - 69,815,344 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,810,965 - 69,815,298 (-)EnsemblGRCm38mm10GRCm38
Cytogenetic Map11B3NCBI
SPEM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,428,857 - 7,432,820 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,428,857 - 7,432,820 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,332,176 - 7,336,139 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map17p13.1NCBI
CHM1_1177,341,228 - 7,345,233 (+)NCBICHM1_1
T2T-CHM13v2.0177,332,911 - 7,336,874 (+)NCBIT2T-CHM13v2.0
Spem3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,030,807 - 55,035,042 (-)NCBIGRCr8
mRatBN7.21054,532,083 - 54,536,318 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,532,099 - 54,536,460 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,194,592 - 59,198,827 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,683,158 - 58,687,393 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,190,809 - 54,195,044 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,418,881 - 56,423,317 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,163,964 - 56,168,441 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1053,686,144 - 53,690,580 (-)NCBICelera
Cytogenetic Map10q24NCBI
SPEM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21915,025,393 - 15,029,850 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11716,990,094 - 16,995,650 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,462,304 - 7,466,931 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,449,056 - 7,453,099 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,449,092 - 7,453,041 (+)Ensemblpanpan1.1panPan2
SPEM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,359,703 - 32,363,779 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,497,807 - 32,501,833 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,465,379 - 32,469,405 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1532,430,613 - 32,434,639 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,389,345 - 32,393,371 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,566,613 - 32,570,639 (+)NCBIUU_Cfam_GSD_1.0
Spem3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,237,480 - 47,241,845 (+)NCBIHiC_Itri_2
SPEM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366605914,599,083 - 14,603,493 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Spem3
193 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116899082672490826Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116899082672490826Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116899082672490826Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116899082672490826Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116899082672490826Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116899082672490826Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116899082672490826Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116899082672490826Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116899082672490826Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001378260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL603707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000210714   ⟹   ENSMUSP00000148194
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,701,791 - 69,706,124 (-)Ensembl
GRCm38.p6 Ensembl1169,810,965 - 69,815,298 (-)Ensembl
RefSeq Acc Id: NM_001378260   ⟹   NP_001365189
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,701,718 - 69,706,170 (-)NCBI
GRCm381169,810,892 - 69,815,344 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001365189 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000148194
  ENSMUSP00000148194.2
Reference Protein Sequences
RefSeq Acc Id: NP_001365189   ⟸   NM_001378260
- UniProtKB: A0A1B0GT45 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000148194   ⟸   ENSMUST00000210714
Protein Domains
Spermatid maturation protein 1 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A1B0GT45-F1-model_v2 AlphaFold A0A1B0GT45 1-1251 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:5622451 AgrOrtholog
Ensembl Genes ENSMUSG00000109737 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000210714 ENTREZGENE
  ENSMUST00000210714.2 UniProtKB/TrEMBL
InterPro SPEM1_N UniProtKB/TrEMBL
MGD MGI:5622451 ENTREZGENE
NCBI Gene Gm39566 ENTREZGENE
PANTHER GENE, 39566-RELATED UniProtKB/TrEMBL
  SPERMATID MATURATION PROTEIN 1 UniProtKB/TrEMBL
Pfam Spem1 UniProtKB/TrEMBL
PhenoGen Spem3 PhenoGen
UniProt A0A1B0GT45 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-08-23 Spem3  SPEM family member 3  Gm39566  predicted gene, 39566  Symbol and/or name updated 27372883 PROVISIONAL