Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732442
Species: Mus musculus
RGD Object: Gene
Symbol: Txn1
Name: thioredoxin 1
Acc ID: CHEBI:9086
Term: (-)-selegiline
Definition: A selegiline that has formula C13H17N.
Chemical ID: MESH:D012642
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Txn1affects response to substanceEXP 6480464CTDTXN protein affects the susceptibility to SelegilinePMID:16099847
Txn1increases expressionEXP 6480464CTDSelegiline results in increased expression of TXN proteinPMID:16099847
Txn1affects response to substanceISOTXN (Homo sapiens)6480464CTDTXN protein affects the susceptibility to SelegilinePMID:16099847
Txn1increases expressionISOTXN (Homo sapiens)6480464CTDSelegiline results in increased expression of TXN proteinPMID:16099847
Txn1multiple interactionsISOTXN (Homo sapiens)6480464CTDDinitrochlorobenzene inhibits the reaction [Selegiline results in increased expression of TXN]; Dinitrochlorobenzene inhibits the reaction [TXN protein affects the susceptibility to Selegiline]; MYC protein affects the reaction [Selegiline results in increased expression of TXN]PMID:16099847
Go Back to source page   Continue to Ontology report