GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ar | multiple interactions | EXP | | 6480464 | CTD | 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Metribolone binds to AR protein] | PMID:16005038 | Ar | affects expression | ISO | Ar (Mus musculus) | 6480464 | CTD | 2,2',4,4'-tetrabromodiphenyl ether affects the expression of AR mRNA | PMID:30294300 | Ar | multiple interactions | ISO | AR (Homo sapiens) | 6480464 | CTD | 2,2',4,4'-tetrabromodiphenyl ether analog binds to and results in decreased activity of AR protein; 2,2',4,4'-tetrabromodiphenyl ether binds to and results in decreased activity of AR protein; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] | PMID:16005038 PMID:16601080 PMID:19672399 PMID:23398518 | |
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